(+)-pilocarpine increases expression EXP 6480464 Pilocarpine results in increased expression of MRE11A mRNA CTD PMID:17971868 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:1344886 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of MRE11 mRNA CTD PMID:22079256 1,1-dichloroethene increases expression ISO RGD:735478 6480464 vinylidene chloride results in increased expression of MRE11A mRNA CTD PMID:26682919 1,2-dimethylhydrazine increases expression ISO RGD:735478 6480464 1, 2-Dimethylhydrazine results in increased expression of MRE11A mRNA CTD PMID:22206623 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:735478 6480464 Tetrachlorodibenzodioxin results in increased expression of MRE11A mRNA CTD PMID:19770486 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:735478 6480464 Tetrachlorodibenzodioxin results in decreased expression of MRE11A mRNA CTD PMID:15034205 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:735478 6480464 AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of MRE11A mRNA] CTD PMID:15034205 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:735478 6480464 Tetrachlorodibenzodioxin affects the expression of MRE11A mRNA CTD PMID:21570461 2,4,6-tribromophenol decreases expression ISO RGD:1344886 6480464 2 more ... CTD PMID:31675489 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of MRE11A mRNA CTD PMID:21346803 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of MRE11A mRNA CTD PMID:21346803 3,3',5,5'-tetrabromobisphenol A increases expression ISO RGD:1344886 6480464 tetrabromobisphenol A results in increased expression of MRE11 protein CTD PMID:31675489 3,4-methylenedioxymethamphetamine decreases expression ISO RGD:735478 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in decreased expression of MRE11A mRNA CTD PMID:26251327 4,4'-diaminodiphenylmethane increases expression ISO RGD:735478 6480464 4, 4'-diaminodiphenylmethane results in increased expression of MRE11A mRNA CTD PMID:18648102 4-hydroperoxycyclophosphamide decreases expression EXP 6480464 perfosfamide results in decreased expression of MRE11A mRNA CTD PMID:11754170 5-aza-2'-deoxycytidine affects localization ISO RGD:1344886 6480464 Decitabine affects the localization of MRE11 protein modified form CTD PMID:17991895 aflatoxin B1 increases expression ISO RGD:735478 6480464 Aflatoxin B1 results in increased expression of MRE11A mRNA CTD PMID:19770486 aflatoxin B1 decreases methylation ISO RGD:1344886 6480464 Aflatoxin B1 results in decreased methylation of MRE11 gene CTD PMID:27153756 all-trans-retinoic acid decreases expression ISO RGD:1344886 6480464 Tretinoin results in decreased expression of MRE11A mRNA CTD PMID:33167477 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of MRE11A mRNA CTD PMID:16483693 amphetamine decreases expression EXP 6480464 Amphetamine results in decreased expression of MRE11A mRNA CTD PMID:30779732 antimycin A decreases expression ISO RGD:1344886 6480464 Antimycin A results in decreased expression of MRE11 mRNA CTD PMID:33512557 aristolochic acid A decreases expression ISO RGD:1344886 6480464 aristolochic acid I results in decreased expression of MRE11 mRNA CTD PMID:33212167 azoxystrobin decreases expression ISO RGD:1344886 6480464 azoxystrobin results in decreased expression of MRE11 mRNA CTD PMID:33512557 benzo[a]pyrene increases expression ISO RGD:735478 6480464 Benzo(a)pyrene results in increased expression of MRE11A mRNA CTD PMID:22228805 benzo[a]pyrene increases expression ISO RGD:1344886 6480464 Benzo(a)pyrene results in increased expression of MRE11A mRNA CTD PMID:28461126 benzo[a]pyrene decreases expression ISO RGD:735478 6480464 Benzo(a)pyrene results in decreased expression of MRE11A mRNA CTD PMID:15034205 benzo[a]pyrene multiple interactions ISO RGD:735478 6480464 AHR protein inhibits the reaction [Benzo(a)pyrene results in decreased expression of MRE11A mRNA] CTD PMID:15034205 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of MRE11A mRNA CTD PMID:25181051 , PMID:27208089 bisphenol A decreases expression ISO RGD:1344886 6480464 bisphenol A results in decreased expression of MRE11 protein CTD PMID:31675489 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of MRE11 mRNA CTD PMID:30816183 more ... bromoacetate increases expression ISO RGD:1344886 6480464 bromoacetate results in increased expression of MRE11 mRNA CTD PMID:19753638 caffeine affects phosphorylation ISO RGD:1344886 6480464 Caffeine affects the phosphorylation of MRE11 protein CTD PMID:35688186 camptothecin decreases expression ISO RGD:1344886 6480464 Camptothecin results in decreased expression of MRE11 mRNA CTD PMID:24792648 capecitabine decreases response to substance ISO RGD:1344886 6480464 MRE11 protein results in decreased susceptibility to Capecitabine CTD PMID:16734730 carbon nanotube increases expression ISO RGD:735478 6480464 Nanotubes more ... CTD PMID:25554681 CGP 52608 multiple interactions ISO RGD:1344886 6480464 CGP 52608 promotes the reaction [RORA protein binds to MRE11A gene] CTD PMID:28238834 chlordecone increases expression ISO RGD:735478 6480464 Chlordecone results in increased expression of MRE11A mRNA CTD PMID:31084621 , PMID:33711761 chlordecone decreases expression ISO RGD:735478 6480464 Chlordecone results in decreased expression of MRE11A mRNA CTD PMID:29980752 chlorpyrifos decreases expression ISO RGD:735478 6480464 Chlorpyrifos results in decreased expression of MRE11A mRNA CTD PMID:20350560 choline multiple interactions ISO RGD:735478 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of MRE11A gene CTD PMID:20938992 chromium(6+) affects expression ISO RGD:1344886 6480464 chromium hexavalent ion affects the expression of MRE11 protein CTD PMID:25173789 cisplatin increases expression ISO RGD:1344886 6480464 Cisplatin results in increased expression of MRE11 protein CTD PMID:26723870 cisplatin multiple interactions ISO RGD:1344886 6480464 [Cisplatin results in decreased susceptibility to Cisplatin] which results in increased expression of MRE11A mRNA CTD PMID:30871063 cisplatin multiple interactions ISO RGD:735478 6480464 NQO1 protein affects the reaction [Cisplatin results in increased expression of MRE11A protein] CTD PMID:26723870 cisplatin increases expression ISO RGD:735478 6480464 Cisplatin results in increased expression of MRE11A protein CTD PMID:26723870 copper atom multiple interactions ISO RGD:1344886 6480464 [Thiosemicarbazones binds to Copper] which results in increased expression of MRE11 protein CTD PMID:20931265 copper(0) multiple interactions ISO RGD:1344886 6480464 [Thiosemicarbazones binds to Copper] which results in increased expression of MRE11 protein CTD PMID:20931265 copper(II) sulfate decreases expression ISO RGD:1344886 6480464 Copper Sulfate results in decreased expression of MRE11 mRNA CTD PMID:19549813 coumarin increases phosphorylation ISO RGD:1344886 6480464 coumarin results in increased phosphorylation of MRE11 protein CTD PMID:35688186 coumestrol multiple interactions ISO RGD:1344886 6480464 [Coumestrol co-treated with 2 more ... CTD PMID:19167446 cyclosporin A decreases expression ISO RGD:1344886 6480464 Cyclosporine results in decreased expression of MRE11 mRNA CTD PMID:20106945 cylindrospermopsin decreases expression ISO RGD:1344886 6480464 cylindrospermopsin results in decreased expression of MRE11 mRNA CTD PMID:23726867 decabromodiphenyl ether increases expression ISO RGD:1344886 6480464 decabromobiphenyl ether results in increased expression of MRE11 protein CTD PMID:31675489 dibutyl phthalate decreases expression ISO RGD:735478 6480464 Dibutyl Phthalate results in decreased expression of MRE11A mRNA CTD PMID:31318015 dicrotophos decreases expression ISO RGD:1344886 6480464 dicrotophos results in decreased expression of MRE11A mRNA CTD PMID:28302478 dioxygen multiple interactions ISO RGD:735478 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of MRE11A mRNA CTD PMID:30529165 doxifluridine decreases response to substance ISO RGD:1344886 6480464 MRE11 protein results in decreased susceptibility to doxifluridine CTD PMID:16734730 doxorubicin decreases expression ISO RGD:1344886 6480464 Doxorubicin results in decreased expression of MRE11 mRNA CTD PMID:29803840 doxorubicin increases phosphorylation EXP 6480464 Doxorubicin results in increased phosphorylation of MRE11 protein CTD PMID:29913208 Enterolactone multiple interactions ISO RGD:1344886 6480464 [Coumestrol co-treated with 2, 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of MRE11 mRNA CTD PMID:19167446 epoxiconazole decreases expression ISO RGD:735478 6480464 epoxiconazole results in decreased expression of MRE11A mRNA CTD PMID:35436446 fenvalerate increases expression EXP 6480464 fenvalerate results in increased expression of MRE11 mRNA CTD PMID:30307764 ferroheme b decreases expression ISO RGD:735478 6480464 Heme metabolite results in decreased expression of MRE11A mRNA CTD PMID:19191707 folic acid multiple interactions ISO RGD:735478 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of MRE11A gene CTD PMID:20938992 heme b decreases expression ISO RGD:735478 6480464 Heme metabolite results in decreased expression of MRE11A mRNA CTD PMID:19191707 hydrogen peroxide affects expression ISO RGD:1344886 6480464 Hydrogen Peroxide affects the expression of MRE11 mRNA CTD PMID:20044591 imiquimod decreases expression ISO RGD:735478 6480464 imiquimod results in decreased expression of MRE11A mRNA CTD PMID:21878529 isocyanates increases expression ISO RGD:735478 6480464 Isocyanates results in increased expression of MRE11A protein CTD PMID:20685613 ivermectin decreases expression ISO RGD:1344886 6480464 Ivermectin results in decreased expression of MRE11 protein CTD PMID:32959892 L-methionine multiple interactions ISO RGD:735478 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of MRE11A gene CTD PMID:20938992 Lasiocarpine multiple interactions ISO RGD:1344886 6480464 [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of MRE11 mRNA CTD PMID:33884520 lipopolysaccharide decreases expression ISO RGD:735478 6480464 Lipopolysaccharides results in decreased expression of MRE11A mRNA CTD PMID:12057914 methyl methanesulfonate increases expression ISO RGD:1344886 6480464 Methyl Methanesulfonate results in increased expression of MRE11 mRNA CTD PMID:23649840 methylmercury chloride decreases expression ISO RGD:1344886 6480464 methylmercuric chloride results in decreased expression of MRE11A mRNA CTD PMID:28001369 monocrotaline multiple interactions ISO RGD:1344886 6480464 [CYP3A4 protein results in increased metabolism of Monocrotaline] which results in decreased expression of MRE11 mRNA CTD PMID:33884520 myristicin decreases expression ISO RGD:1344886 6480464 myristicin results in decreased expression of MRE11 mRNA CTD PMID:24792648 N,N-dimethylformamide increases expression ISO RGD:1344886 6480464 Dimethylformamide results in increased expression of MRE11 mRNA, Dimethylformamide results in increased expression of MRE11 protein CTD PMID:26387567 N-nitrosodiethylamine increases expression ISO RGD:735478 6480464 Diethylnitrosamine results in increased expression of MRE11A mRNA, Diethylnitrosamine results in increased expression of MRE11A protein CTD PMID:17854601 N-nitrosodiethylamine multiple interactions ISO RGD:735478 6480464 RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of MRE11A mRNA], RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of MRE11A protein] CTD PMID:17854601 Nonidet P-40 increases expression ISO RGD:1344886 6480464 Nonidet P-40 results in increased expression of MRE11A mRNA CTD PMID:26552463 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of MRE11A mRNA CTD PMID:25729387 ozone multiple interactions ISO RGD:735478 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of MRE11A mRNA, [Air Pollutants results in increased abundance of Ozone] which results in increased expression of MRE11A mRNA CTD PMID:34911549 paracetamol affects expression ISO RGD:735478 6480464 Acetaminophen affects the expression of MRE11A mRNA CTD PMID:17562736 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of MRE11A mRNA CTD PMID:33387578 paracetamol increases expression ISO RGD:1344886 6480464 Acetaminophen results in increased expression of MRE11 mRNA CTD PMID:22230336 pentamidine decreases activity ISO RGD:1344886 6480464 Pentamidine results in decreased activity of MRE11 protein CTD PMID:20144237 picoxystrobin decreases expression ISO RGD:1344886 6480464 picoxystrobin results in decreased expression of MRE11 mRNA CTD PMID:33512557 pirinixic acid multiple interactions ISO RGD:735478 6480464 PPARA protein promotes the reaction [pirinixic acid results in increased expression of MRE11A mRNA] CTD PMID:17950772 pirinixic acid increases expression ISO RGD:735478 6480464 pirinixic acid results in increased expression of MRE11A mRNA CTD PMID:17950772 more ... potassium chromate multiple interactions ISO RGD:1344886 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of MRE11 mRNA CTD PMID:22079256 potassium chromate decreases expression ISO RGD:1344886 6480464 potassium chromate(VI) results in decreased expression of MRE11 mRNA CTD PMID:22079256 quercetin decreases expression ISO RGD:1344886 6480464 Quercetin results in decreased expression of MRE11 mRNA CTD PMID:21632981 quercetin decreases expression ISO RGD:735478 6480464 Quercetin results in decreased expression of MRE11A mRNA CTD PMID:25862958 resveratrol multiple interactions ISO RGD:1344886 6480464 [Coumestrol co-treated with Resveratrol] results in increased expression of MRE11 mRNA more ... CTD PMID:19167446 more ... resveratrol decreases expression EXP 6480464 Resveratrol results in decreased expression of MRE11 mRNA CTD PMID:33775663 resveratrol decreases expression ISO RGD:735478 6480464 resveratrol results in decreased expression of MRE11A protein CTD PMID:25505154 resveratrol decreases expression ISO RGD:1344886 6480464 resveratrol results in decreased expression of MRE11 protein CTD PMID:22644231 riddelliine multiple interactions ISO RGD:1344886 6480464 [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of MRE11 mRNA CTD PMID:33884520 rotenone increases expression ISO RGD:1344886 6480464 Rotenone results in increased expression of MRE11 mRNA CTD PMID:18191903 rotenone decreases expression ISO RGD:1344886 6480464 Rotenone results in decreased expression of MRE11 mRNA CTD PMID:33512557 sunitinib decreases expression ISO RGD:1344886 6480464 Sunitinib results in decreased expression of MRE11 mRNA CTD PMID:31533062 T-2 toxin decreases expression ISO RGD:1344886 6480464 T-2 Toxin results in decreased expression of MRE11A mRNA CTD PMID:34581912 testosterone multiple interactions ISO RGD:735478 6480464 1 more ... CTD PMID:33848595 testosterone increases expression ISO RGD:735478 6480464 Testosterone deficiency results in increased expression of MRE11A mRNA CTD PMID:33848595 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of MRE11A mRNA CTD PMID:23411599 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of MRE11A mRNA CTD PMID:25729387 trimellitic anhydride increases expression ISO RGD:735478 6480464 trimellitic anhydride results in increased expression of MRE11A mRNA CTD PMID:19042947 valproic acid decreases expression ISO RGD:735478 6480464 Valproic Acid results in decreased expression of MRE11A mRNA CTD PMID:21427059 valproic acid decreases expression ISO RGD:1344886 6480464 Valproic Acid results in decreased expression of MRE11 mRNA CTD PMID:23179753 , PMID:27188386 veliparib decreases response to substance ISO RGD:1344886 6480464 MRE11 protein results in decreased susceptibility to veliparib CTD PMID:21300766 zinc atom decreases expression ISO RGD:1344886 6480464 Zinc deficiency results in decreased expression of MRE11 mRNA CTD PMID:18356318 zinc(0) decreases expression ISO RGD:1344886 6480464 Zinc deficiency results in decreased expression of MRE11 mRNA CTD PMID:18356318