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Gene: Il6 (interleukin 6) Rattus norvegicus
Symbol: Il6
Name: interleukin 6
RGD ID: 2901
Description: Exhibits cytokine activity and interleukin-6 receptor binding activity. Involved in several processes, including cellular response to lipid; positive regulation of cell communication; and response to peptide hormone. Localizes to cytoplasm and extracellular space. Used to study several diseases, including congestive heart failure; disseminated intravascular coagulation; fatty liver disease; hypertension (multiple); and impotence. Biomarker of several diseases, including artery disease (multiple); auditory system disease (multiple); iron deficiency anemia; lung disease (multiple); and middle cerebral artery infarction. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); gastrointestinal system cancer (multiple); glucose metabolism disease (multiple); and periodontal disease (multiple). Orthologous to human IL6 (interleukin 6); PARTICIPATES IN interleukin-6 signaling pathway; pro-inflammatory cytokine mediated pathway; interleukin-23 signaling pathway; INTERACTS WITH (+)-alpha-tocopherol; (+)-pilocarpine; (+)-sesamin.
Type: protein-coding
Also known as: Ifnb2; IL-6; ILg6; Interleukin 6 (interferon beta 2); Interleukin 6 (interferon, beta 2); interleukin-6
Homo sapiens (human) : IL6 (interleukin 6)  HGNC  Alliance
Mus musculus (house mouse) : Il6 (interleukin 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il6 (interleukin 6)
Pan paniscus (bonobo/pygmy chimpanzee) : IL6 (interleukin 6)
Canis lupus familiaris (dog) : IL6 (interleukin 6)
Sus scrofa (pig) : IL6 (interleukin 6)
Chlorocebus sabaeus (African green monkey) : IL6 (interleukin 6)
Heterocephalus glaber (naked mole-rat) : Il6 (interleukin 6)
more info ...
Is Marker For: Strains:   SHR.BN-(Il6-Npy)   BN.SHR-(Il6-Cd36)/Cub  
QTLs:   Bp33   Scl23   Bp79   Plsm1   Stl2   Bp330  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.043,043,231 - 3,047,807 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl43,043,231 - 3,047,807 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.043,095,536 - 3,100,112 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44456,799 - 461,376 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14456,798 - 461,376 (-)NCBI
Celera45,093,593 - 5,098,169 (+)NCBICelera
Cytogenetic Map4q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)