Slc39a8 (solute carrier family 39 member 8)

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Gene: Slc39a8 (solute carrier family 39 member 8) Rattus norvegicus

Analyze

Symbol:

Slc39a8

Name:

solute carrier family 39 member 8

RGD ID:

1308236

Description:

Predicted to enable solute:monoatomic cation symporter activity and transition metal ion transmembrane transporter activity. Involved in monoatomic cation transmembrane transport. Located in plasma membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIn. Orthologous to human SLC39A8 (solute carrier family 39 member 8); PARTICIPATES IN iron uptake pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC108350117; LOC295455; metal cation symporter ZIP8; MGC108852; solute carrier family 39 (metal ion transporter), member 8; solute carrier family 39 (zinc transporter), member 8; uncharacterized LOC108350117; zinc transporter ZIP8; ZIP-8; zrt- and Irt-like protein 8

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	2	224,171,787 - 224,319,326 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	224,256,654 - 224,319,129 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	231,982,580 - 232,044,754 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	2	229,882,319 - 229,944,486 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	2	224,746,913 - 224,809,087 (+)	NCBI	Rnor_WKY
Rnor_6.0	2	241,028,851 - 241,092,584 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	241,029,693 - 241,092,582 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	259,584,747 - 259,648,098 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	233,340,397 - 233,403,461 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	233,327,136 - 233,390,197 (+)	NCBI
Celera	2	216,458,405 - 216,522,357 (+)	NCBI		Celera
Cytogenetic Map	2	q43	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

beta-mannosidosis (ISO)

congenital disorder of glycosylation type IIn (ISO)

Experimental Liver Cirrhosis (ISO)

left ventricular noncompaction (ISS)

Manganese Poisoning (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (EXP)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP,ISO)

17beta-estradiol 3-benzoate (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

2-butoxyethanol (ISO)

3,3',4,4',5-pentachlorobiphenyl (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-diaminodiphenylmethane (EXP)

5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole (EXP)

6-propyl-2-thiouracil (EXP)

8-Br-cAMP (ISO)

acetamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amiodarone (EXP)

amphetamine (EXP)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

benzbromarone (EXP)

benzo[a]pyrene (ISO)

benzoates (ISO)

beta-naphthoflavone (ISO)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

C60 fullerene (EXP)

cadmium atom (EXP,ISO)

cadmium dichloride (EXP,ISO)

calcitriol (ISO)

carbon nanotube (ISO)

chloroprene (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

clofibrate (EXP)

cobalt atom (EXP)

copper atom (EXP)

copper(0) (EXP)

copper(II) sulfate (ISO)

coumestrol (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

dextran sulfate (ISO)

diethylstilbestrol (ISO)

diuron (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

Enterolactone (ISO)

flutamide (EXP)

genistein (ISO)

gentamycin (EXP)

glafenine (EXP)

hydrogencarbonate (ISO)

iron atom (EXP,ISO)

iron(0) (EXP,ISO)

isotretinoin (ISO)

L-ethionine (EXP)

lead diacetate (EXP,ISO)

manganese atom (EXP,ISO)

manganese(0) (EXP,ISO)

manganese(II) chloride (EXP)

mercury atom (ISO)

mercury dibromide (ISO)

mercury(0) (ISO)

methapyrilene (EXP)

methotrexate (ISO)

methylmercury chloride (ISO)

N-methylformamide (ISO)

N-nitrosodimethylamine (EXP)

nefazodone (EXP)

nickel atom (ISO)

nimesulide (EXP)

nitrofen (EXP)

omeprazole (EXP)

panobinostat (ISO)

paracetamol (EXP)

phenobarbital (ISO)

phenylmercury acetate (ISO)

pirinixic acid (EXP,ISO)

potassium cyanide (ISO)

progesterone (ISO)

propanal (ISO)

quercitrin (ISO)

resveratrol (ISO)

rimonabant (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

sodium hydrogencarbonate (EXP)

Soman (EXP)

sunitinib (ISO)

testosterone (EXP,ISO)

tetrachloromethane (EXP,ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

toluene (EXP)

topotecan (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

triclosan (ISO)

triptonide (ISO)

valproic acid (ISO)

vancomycin (ISO)

vorinostat (ISO)

zinc atom (EXP,ISO)

zinc dichloride (EXP)

zinc(0) (EXP,ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

arginine metabolic process (ISO,ISS)

bicarbonate transport (ISO,ISS)

cadmium ion transmembrane transport (IDA,ISO)

cartilage homeostasis (ISO,ISS)

cobalt ion transport (IDA)

DNA-templated transcription (ISO)

extracellular matrix organization (ISO,ISS)

inorganic anion transport (IEA)

intracellular manganese ion homeostasis (ISO,ISS)

intracellular zinc ion homeostasis (IBA,ISO,ISS)

iron ion import across plasma membrane (IDA,ISO)

leukocyte adhesion to arterial endothelial cell (ISO,ISS)

manganese ion transmembrane transport (IDA,ISO)

mercury ion transport (ISO)

mitochondrial manganese ion transmembrane transport (ISO,ISS)

negative regulation of I-kappaB kinase/NF-kappaB signaling (ISO)

negative regulation of inflammatory response (ISO)

obsolete intracellular cadmium ion homeostasis (ISO,ISS)

plasma membrane selenite transport (ISO)

protein N-linked glycosylation (ISO,ISS)

regulation of DNA-templated transcription (ISO,ISS)

regulation of membrane potential (ISO,ISS)

zinc ion import across plasma membrane (IBA,IDA,ISO)

zinc ion transmembrane transport (ISO)

zinc ion transport (ISO,ISS)

Cellular Component

apical plasma membrane (ISO,ISS)

basolateral plasma membrane (ISO,ISS)

lysosomal membrane (ISO,ISS)

organelle membrane (ISO,ISS)

plasma membrane (IBA,IDA,ISO)

Molecular Function

bicarbonate transmembrane transporter activity (ISO)

cadmium ion transmembrane transporter activity (ISO)

iron ion transmembrane transporter activity (ISO)

manganese ion transmembrane transporter activity (ISO)

monoatomic anion:monoatomic cation symporter activity (ISO)

monoatomic cation:bicarbonate symporter activity (IC,ISO,ISS)

selenite:proton symporter activity (ISO)

zinc ion transmembrane transporter activity (IBA,ISO)

zinc:bicarbonate symporter activity (IC,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

iron uptake pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Regulators of Iron Homeostasis: New Players in Metabolism, Cell Death, and Disease.	Bogdan AR, etal., Trends Biochem Sci. 2016 Mar;41(3):274-86. doi: 10.1016/j.tibs.2015.11.012. Epub 2015 Dec 23.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Cellular iron uptake, trafficking and metabolism: Key molecules and mechanisms and their roles in disease.	Lane DJ, etal., Biochim Biophys Acta. 2015 May;1853(5):1130-44. doi: 10.1016/j.bbamcr.2015.01.021. Epub 2015 Feb 4.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
6.	GOA pipeline	RGD automated data pipeline
7.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
9.	ZIP8 is an iron and zinc transporter whose cell-surface expression is up-regulated by cellular iron loading.	Wang CY, etal., J Biol Chem. 2012 Oct 5;287(41):34032-43. doi: 10.1074/jbc.M112.367284. Epub 2012 Aug 16.

Additional References at PubMed

PMID:12477932	PMID:12504855	PMID:15722412	PMID:16638970	PMID:17108009	PMID:18037372	PMID:18390834	PMID:19401385	PMID:21509381	PMID:23598904	PMID:24529376	PMID:25007852
PMID:27166256	PMID:27466201	PMID:28338971	PMID:28481222	PMID:29337306	PMID:29453449	PMID:30015240	PMID:31699897	PMID:33677133

Genomics

Comparative Map Data

Slc39a8
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	2	224,171,787 - 224,319,326 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	224,256,654 - 224,319,129 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	231,982,580 - 232,044,754 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	2	229,882,319 - 229,944,486 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	2	224,746,913 - 224,809,087 (+)	NCBI	Rnor_WKY
Rnor_6.0	2	241,028,851 - 241,092,584 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	241,029,693 - 241,092,582 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	259,584,747 - 259,648,098 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	233,340,397 - 233,403,461 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	233,327,136 - 233,390,197 (+)	NCBI
Celera	2	216,458,405 - 216,522,357 (+)	NCBI		Celera
Cytogenetic Map	2	q43	NCBI

SLC39A8
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	102,251,041 - 102,345,482 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	4	102,251,080 - 102,431,258 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	103,172,198 - 103,266,639 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	103,401,844 - 103,485,371 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	4	103,539,998 - 103,623,526	NCBI
Celera	4	100,470,678 - 100,565,146 (-)	NCBI		Celera
Cytogenetic Map	4	q24	NCBI
HuRef	4	98,909,550 - 99,003,934 (-)	NCBI		HuRef
CHM1_1	4	103,148,714 - 103,243,025 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	4	105,565,252 - 105,659,701 (-)	NCBI		T2T-CHM13v2.0

Slc39a8
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	135,522,644 - 135,594,333 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	135,531,040 - 135,594,333 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	135,816,882 - 135,888,572 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	135,825,279 - 135,888,572 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	135,488,455 - 135,551,536 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	135,763,475 - 135,825,778 (+)	NCBI		MGSCv36	mm8
Celera	3	142,245,991 - 142,312,950 (+)	NCBI		Celera
Cytogenetic Map	3	G3	NCBI
cM Map	3	63.04	NCBI

Slc39a8
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955496	6,040,029 - 6,109,907 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955496	6,016,727 - 6,106,965 (+)	NCBI	ChiLan1.0	ChiLan1.0

SLC39A8
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	4	105,339,488 - 105,433,813 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	105,339,488 - 105,433,568 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	4	94,675,458 - 94,770,380 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

SLC39A8
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	32	23,727,920 - 23,801,459 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	32	23,729,476 - 23,800,941 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	32	18,223,143 - 18,296,028 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	32	23,949,019 - 24,021,586 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	32	23,949,029 - 24,022,702 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	32	23,928,002 - 24,000,562 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	32	23,708,061 - 23,781,012 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	32	16,083,043 - 16,156,566 (+)	NCBI		UU_Cfam_GSD_1.0

Slc39a8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405301	17,620,065 - 17,693,363 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936520	962,756 - 1,037,274 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936520	961,376 - 1,036,801 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC39A8
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	118,605,402 - 118,678,107 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	8	118,604,852 - 118,678,115 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	127,753,647 - 127,825,292 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC39A8
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	50,355,756 - 50,451,253 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	50,367,436 - 50,451,510 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	28,867,139 - 28,956,324 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc39a8
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624830	5,514,780 - 5,574,894 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624830	5,514,595 - 5,573,250 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Slc39a8
982 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	157
Count of miRNA genes:	109
Interacting mature miRNAs:	135
Transcripts:	ENSRNOT00000033413
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354648	Bp239	Blood pressure QTL 239		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	66118463	226797303	Rat
724534	Uae6	Urinary albumin excretion QTL 6	10		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	2	78665619	249053267	Rat
1354649	Kidm17	Kidney mass QTL 17	2.9		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	2	81754530	227146641	Rat
1641891	Alcrsp17	Alcohol response QTL 17			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	149559561	249053267	Rat
8662843	Vetf9	Vascular elastic tissue fragility QTL 9	2.05		thoracic aorta molecular composition trait (VT:0010568)	aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)	2	157142078	226277316	Rat
2306901	Bp337	Blood pressure QTL 337		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	164073756	227146641	Rat
2300189	Bmd48	Bone mineral density QTL 48	5.8	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	2	179335906	224335906	Rat
61417	Cia10	Collagen induced arthritis QTL 10	3.4		joint integrity trait (VT:0010548)	experimental arthritis severity measurement (CMO:0001459)	2	179946951	224946951	Rat
8694435	Bw166	Body weight QTL 166	14.08	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	2	182171407	227171407	Rat
9589044	Scfw1	Subcutaneous fat weight QTL 1	5.8	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	2	182171407	227171407	Rat
8694383	Bw158	Body weight QTL 158	7.69	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	2	182171407	227171407	Rat
8694194	Abfw1	Abdominal fat weight QTL 1	11.7	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	2	182171407	227171407	Rat
738013	Alc15	Alcohol consumption QTL 15	4.1	0.00022	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	2	184165752	229165752	Rat
1581499	Esta2	Estrogen-induced thymic atrophy QTL 2			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	2	189599258	226936289	Rat
61366	Iddm3	Insulin dependent diabetes mellitus QTL 3	4.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	189599258	234599258	Rat
61398	Bp50	Blood pressure QTL 50	4.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	189599258	234599258	Rat
2301408	Kidm36	Kidney mass QTL 36		0.002	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	190613715	226808892	Rat
2317752	Glom23	Glomerulus QTL 23	3.6		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	2	193452645	245889826	Rat
1598813	Memor9	Memory QTL 9	2.7		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	2	199341726	234244620	Rat
1598835	Anxrr18	Anxiety related response QTL 18	2.98		body movement coordination trait (VT:0005424)	number of rearing movements in an experimental apparatus (CMO:0001752)	2	200990457	245990457	Rat
2298479	Eau5	Experimental allergic uveoretinitis QTL 5		0.0021	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	2	202446871	237938339	Rat
7207490	Bss111	Bone structure and strength QTL 111	6.4		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	2	211744537	249053267	Rat
7207482	Bss107	Bone structure and strength QTL 107	7		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	2	211744537	249053267	Rat
7207484	Bss108	Bone structure and strength QTL 108	5.3		femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	2	211744537	249053267	Rat
1298075	Scl17	Serum cholesterol level QTL 17	3.4		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	2	211744537	249053267	Rat
1549836	Bss2	Bone structure and strength QTL 2	7.5		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	2	211744537	249053267	Rat
2317885	Alcrsp28	Alcohol response QTL 28	2.1	0.63	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	212828222	249053267	Rat
1300126	Bp175	Blood pressure QTL 175	3.46		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	214226044	247136170	Rat
2313073	Bmd75	Bone mineral density QTL 75	4.1	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	2	215377404	237938339	Rat
1331767	Hrtrt12	Heart rate QTL 12	3.373		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	2	218414747	240841241	Rat
1359019	Hrtrt19	Heart rate QTL 19	2.9		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	2	219753301	226277316	Rat
2293833	Kiddil8	Kidney dilation QTL 8	2.9		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	219753301	247136170	Rat
2293844	Kiddil7	Kidney dilation QTL 7	3.5		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	219753301	247136170	Rat
9587428	Epfw6	Epididymal fat weight QTL 6	7.47	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	2	223389739	249053267	Rat
7411555	Bw132	Body weight QTL 132		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	2	223389739	249053267	Rat

Markers in Region

AI501854

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	224,318,762 - 224,318,968 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	241,092,021 - 241,092,226	NCBI	Rnor6.0
Rnor_5.0	2	259,647,535 - 259,647,740	UniSTS	Rnor5.0
RGSC_v3.4	2	233,403,091 - 233,403,296	UniSTS	RGSC3.4
Celera	2	216,521,987 - 216,522,192	UniSTS
RH 3.4 Map	2	1564.2	UniSTS
Cytogenetic Map	2	q43	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	12	41	41	4	41			18	35	27	11
Low		31	16		15		8	10	56		14		8
Below cutoff								1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001011952	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006233356	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006233357	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017590787	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039102102	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039102104	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC089844	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473952	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000079	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000033413 ⟹ ENSRNOP00000030977

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	224,256,654 - 224,319,129 (+)	Ensembl
Rnor_6.0 Ensembl	2	241,029,693 - 241,092,582 (+)	Ensembl

RefSeq Acc Id:

NM_001011952 ⟹ NP_001011952

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	224,256,654 - 224,319,133 (+)	NCBI
Rnor_6.0	2	241,029,669 - 241,092,391 (+)	NCBI
Rnor_5.0	2	259,584,747 - 259,648,098 (+)	NCBI
RGSC_v3.4	2	233,340,397 - 233,403,461 (+)	RGD
Celera	2	216,458,405 - 216,522,357 (+)	RGD

Sequence:

show sequence

CCTTTGTTCCTTTTATCTCAGGCTCCGCAGGAGGCCCGGAGAGGCCACACTGCCTACCGTCCTC
CTGGCTGTGGTACCTCTTCAATGCCCCGAAGGTCTGAGGCTGCAGAGGAGCGGGGGCACCGAGC
TTCTCGCTAACTGGGGCAGGCAGTGACGTGAGACCGGCGGACCTCCCACCCCCACCCTAAGGGC
ACCGACACCCGGGCACTCGCTCGGATCCCTGCATCCGCTAGCTCCGGAGCTGCGCGCTCCACGA
TGGCTCCGGGCCGGGCAGTGGCCGGGCTGCTGCTACTGGCGGCCACCGGCCTGGGACGCCCCTC
GGAGGGGCCGGAGCTCGCCTTCACTGAGGATGTGCTGAGAGTGTTCGGCGCCAACCAGAGCCTG
TCGGCCGCGCAGCTGGGGCGCCTGCTGGAGCGCCTGGGGGCTGCACCCCAGCAGGGAGCGCTGG
AGCTGGGCCAGCTCCACTTCAACCAGTGTCTGTCAGCGGAAGACATCTTTTCTCTTCATGGTTT
CTCAAACGTCACCCAGATAACCAGCTCGAACTTCACTGCCATCTGCCCTGCGATCTTACAGCAG
CTGAACTTTCATCCCTGTGAGGATCCACAGAAGCACAGCGTAAAGCCCAGTTTTTCCGAAGTCT
GGGGCTATGGATTCTTGTCAGTGACAATCATCAATTTGGCCTCTCTCCTGGGATTGATTTTAAC
CCCCTTGATAAAGAAGTCGTATTTCCCCAAGATTTTGACTTATTTTGTGGGGCTGGCTATTGGG
ACCCTTTTCTCAAATGCCATTTTCCAGCTTATTCCAGAGGCATTTGGATTTAATCCCAAAATTG
ACAATTATGTTGAAAAGGCAGTTGCTGTGTTTGGTGGATTTTACATGCTTTTCTTTGTTGAAAG
AACACTTAAGATGCTACTGAAAACGTACGGCCAGAATGACCATACTCACTTCAGGAATGATGAC
TTCGGTTCTAAAGAAAAAGCCCATCAACCCAAAACGTTGCCATTACCTCCTGTCAATGGAGTGA
CATGCTATGCCAACCCCGCTGTCACTGAGCCTAATGGACACATCCACTTCGACACTGTCAGTGT
TGTGTCCCTGCAGGATGGAAAAGCAGAGTCAAGTTCATGCACCTGTTTGAAGGGGCCCAAACTG
TCAGAAATAGGAACGATTGCTTGGATGATCACGCTCTGTGATGCCCTTCACAATTTCATTGATG
GCTTGGCGATCGGGGCATCCTATACTCTGTCTCTTCTTCAAGGACTCAGTACTTCCATAGCGAT
CCTGTGTGAGGAGTTTCCTCATGAGTTAGGGGACTTTGTGATCTTGCTCAATGCAGGGATGAGC
ACTCGGCAAGCCTTGCTGTTTAACTTCCTCTCTGCATGTTCCTGCTACGTTGGGCTTGCTTTCG
GCATTTTGGTGGGCAACAACTTTGCTCCAAATATTATATTTGCACTTGCTGGAGGCATGTTCCT
TTACATTTCTCTGGCAGATATGTTTCCAGAGATGAACGACATGCTGAGAGAAAAAGTAACTGGA
AGACAAACGGACTTCACCTTCTTCATGATCCAGAACGCAGGGATGTTAACCGGATTCACTGCCA
TCTTGCTCATCACCTTGTACGCAGGGGACATCGAATTGCAGTAGCTGGGAGTATGACGTCAGCG
CGGCAAGGCATTTAATAAACAACAACACAGAAGAAACATCTCCATAGGGAATTTTTTTAAAAAA
GTGTATCCTATTTAGTTAAAAGAGATTTTTTTTTTAAATTTTCAACTAGAGGCTAAGAAATCTA
ATGACTGGTTTCAGACACGTAGAATAGGTGAAATTTGTTGTTAAAAATTTCTTTAAAAGGTTTT
CGGTTTCAGTCTGAAATGGCTGGTGTATGGGGCCTTTGGTAAATACCTGTTTTTCAATATTTTA
TGCCTATTAGAAAATTATCATGAAGCAAACACATGCATTCAGTAGCAGACATACAGACCCAGAG
AAAAACACAATCTGAGTCATGCAAGGCTTTAGAACTTGGTTGGATTAAACACACACACACACAC
ACACACACACACACACACACACACACACACACACACACGTGTTTTCAGGGTGGTTTTCTTCCGA
TTAATGTGTTCGTCTGCTTTTAAAGGCAGGTGCTTCAAATGTGGAAGGAAATCAAAACAGTTCC
AGTGCATGCAGGAAGGATTCCAGTGCCTTAATGAACCCCAGAGAGATTGTGCACAGCGTTTGTT
CAGCTTTTTGTCTCAGTTGGCGACCTGTAGGATTGTTTTGAAAGCTATCCCAAAGTAACATGAA
TTAGGAAAGGATGAGAGTCTTGCTAGCCAGGTGAAGCTTGGGCTTAGTGCTTGGTCCCTGAGTA
TATAAGCTTGAACACACTCTGCAGAAGACCAGAATTTGCTGTGCTGTGACTTAGGTTGTGGTTC
CAGACAACAGAAATGGCCGAGGAGTAAGACTGGTCAGAACGCAGTCGTGCCGTGCTCTGGGATT
GCTTTGTAAGGGTGAAGAATGTGTTGGGTGGGAGAGAGAAATTGAATATAATTTTGAGCAATTT
ACTTTTTTAAAGGTGAGCATAATTATTTAGCAGGGAGGATTTCAATAAATGCAAAATAACAGCT
GGGCTGGGCTGTGTCAGAGACTGATGGTGGAGGAAGCGTGTGTTCATTAGGGGTGACTGACAGT
CAGAAACATCTTCTTTTATGCCCAGCATACTTTGTTCCCATATGCTATACCTTTGGATGGAAAA
CACTCAACATACTGTGCTTATTTTTCTACCTTTGGTAAAACACAGAGCTCGCTGAGTTTTTGAG
CAGGCTGTAGACAATTAGTCTGAATTGAACATCCCAATCTCAATTCACACTCCCAAGGAACCCA
AAAGAGATGATTTGACAGTGATGAGGATGATTAATAGAACACAACTTATCCCAGGATTGTGTTT
CCCTATAAGCCAAAACACATTTTCATGTAAGAACAATGCAAACTCGATAAACGTTAACATATAT
GTTTGTGTGTTTCACTCTATGACTGACAATTAAAACTTATTTGACCAGACAGTAAACGATTTTA
AAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006233356 ⟹ XP_006233418

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	224,256,108 - 224,319,326 (+)	NCBI
Rnor_6.0	2	241,029,188 - 241,092,584 (+)	NCBI
Rnor_5.0	2	259,584,747 - 259,648,098 (+)	NCBI

Sequence:

show sequence

GAGAGAGAGAGAGAGAGAGAGAGAGAGAGAATATTTAAACCTTAGGGACCGACCGAAGAGGCTC
CGCAGGAGGCCCGGAGAGGCCACACTGCCTACCGTCCTCCTGGCTGTGGTACCTCTTCAATGCC
CCGAAGGTCTGAGGCTGCAGAGGAGCGGGGGCACCGAGCTTCTCGCTAACTGGGGCAGGCAGTG
ACGTGAGACCGGCGGACCTCCCACCCCCACCCTAAGGGCACCGACACCCGGGCACTCGCTCGGA
TCCCTGCATCCGCTAGCTCCGGAGCTGCGCGCTCCACGATGGCTCCGGGCCGGGCAGTGGCCGG
GCTGCTGCTACTGGCGGCCACCGGCCTGGGACGCCCCTCGGAGGGGCCGGAGCTCGCCTTCACT
GAGGATGTGCTGAGAGTGTTCGGCGCCAACCAGAGCCTGTCGGCCGCGCAGCTGGGGCGCCTGC
TGGAGCGCCTGGGGGCTGCACCCCAGCAGGGAGCGCTGGAGCTGGGCCAGCTCCACTTCAACCA
GTGTCTGTCAGCGGAAGACATCTTTTCTCTTCATGGTTTCTCAAACGTCACCCAGATAACCAGC
TCGAACTTCACTGCCATCTGCCCTGCGATCTTACAGCAGCTGAACTTTCATCCCTGTGAGGATC
CACAGAAGCACAGCGTAAAGCCCAGTTTTTCCGAAGTCTGGGGCTATGGATTCTTGTCAGTGAC
AATCATCAATTTGGCCTCTCTCCTGGGATTGATTTTAACCCCCTTGATAAAGAAGTCGTATTTC
CCCAAGATTTTGACTTATTTTGTGGGGCTGGCTATTGGGACCCTTTTCTCAAATGCCATTTTCC
AGCTTATTCCAGAGGCATTTGGATTTAATCCCAAAATTGACAATTATGTTGAAAAGGCAGTTGC
TGTGTTTGGTGGATTTTACATGCTTTTCTTTGTTGAAAGAACACTTAAGATGCTACTGAAAACG
TACGGCCAGAATGACCATACTCACTTCAGGAATGATGACTTCGGTTCTAAAGAAAAAGCCCATC
AACCCAAAACGTTGCCATTACCTCCTGTCAATGGAGTGACATGCTATGCCAACCCCGCTGTCAC
TGAGCCTAATGGACACATCCACTTCGACACTGTCAGTGTTGTGTCCCTGCAGGATGGAAAAGCA
GAGTCAAGTTCATGCACCTGTTTGAAGGGGCCCAAACTGTCAGAAATAGGAACGATTGCTTGGA
TGATCACGCTCTGTGATGCCCTTCACAATTTCATTGATGGCTTGGCGATCGGGGCATCCTATAC
TCTGTCTCTTCTTCAAGGACTCAGTACTTCCATAGCGATCCTGTGTGAGGAGTTTCCTCATGAG
TTAGGGGACTTTGTGATCTTGCTCAATGCAGGGATGAGCACTCGGCAAGCCTTGCTGTTTAACT
TCCTCTCTGCATGTTCCTGCTACGTTGGGCTTGCTTTCGGCATTTTGGTGGGCAACAACTTTGC
TCCAAATATTATATTTGCACTTGCTGGAGGCATGTTCCTTTACATTTCTCTGGCAGATATGTTT
CCAGAGATGAACGACATGCTGAGAGAAAAAGTAACTGGAAGACAAACGGACTTCACCTTCTTCA
TGATCCAGAACGCAGGGATGTTAACCGGATTCACTGCCATCTTGCTCATCACCTTGTACGCAGG
GGACATCGAATTGCAGTAGCTGGGAGTATGACGTCAGCGCGGCAAGGCATTTAATAAACAACAA
CACAGAAGAAACATCTCCATAGGGAATTTTTTTAAAAAAGTGTATCCTATTTAGTTAAAAGAGA
TTTTTTTTTTAAATTTTCAACTAGAGGCTAAGAAATCTAATGACTGGTTTCAGACACGTAGAAT
AGGTGAAATTTGTTGTTAAAAATTTCTTTAAAAGGTTTTCGGTTTCAGTCTGAAATGGCTGGTG
TATGGGGCCTTTGGTAAATACCTGTTTTTCAATATTTTATGCCTATTAGAAAATTATCATGAAG
CAAACACATGCATTCAGTAGCAGACATACAGACCCAGAGAAAAACACAATCTGAGTCATGCAAG
GCTTTAGAACTTGGTTGGATTAAACACACACACACACACACACACACACACACACACACACACA
CACACACACACACGTGTTTTCAGGGTGGTTTTCTTCCGATTAATGTGTTCGTCTGCTTTTAAAG
GCAGGTGCTTCAAATGTGGAAGGAAATCAAAACAGTTCCAGTGCATGCAGGAAGGATTCCAGTG
CCTTAATGAACCCCAGAGAGATTGTGCACAGCGTTTGTTCAGCTTTTTGTCTCAGTTGGCGACC
TGTAGGATTGTTTTGAAAGCTATCCCAAAGTAACATGAATTAGGAAAGGATGAGAGTCTTGCTA
GCCAGGTGAAGCTTGGGCTTAGTGCTTGGTCCCTGAGTATATAAGCTTGAACACACTCTGCAGA
AGACCAGAATTTGCTGTGCTGTGACTTAGGTTGTGGTTCCAGACAACAGAAATGGCCGAGGAGT
AAGACTGGTCAGAACGCAGTCGTGCCGTGCTCTGGGATTGCTTTGTAAGGGTGAAGAATGTGTT
GGGTGGGAGAGAGAAATTGAATATAATTTTGAGCAATTTACTTTTTTAAAGGTGAGCATAATTA
TTTAGCAGGGAGGATTTCAATAAATGCAAAATAACAGCTGGGCTGGGCTGTGTCAGAGACTGAT
GGTGGAGGAAGCGTGTGTTCATTAGGGGTGACTGACAGTCAGAAACATCTTCTTTTATGCCCAG
CATACTTTGTTCCCATATGCTATACCTTTGGATGGAAAACACTCAACATACTGTGCTTATTTTT
CTACCTTTGGTAAAACACAGAGCTCGCTGAGTTTTTGAGCAGGCTGTAGACAATTAGTCTGAAT
TGAACATCCCAATCTCAATTCACACTCCCAAGGAACCCAAAAGAGATGATTTGACAGTGATGAG
GATGATTAATAGAACACAACTTATCCCAGGATTGTGTTTCCCTATAAGCCAAAACACATTTTCA
TGTAAGAACAATGCAAACTCGATAAACGTTAACATATATGTTTGTGTGTTTCACTCTATGACTG
ACAATTAAAACTTATTTGACCAGACAGTAAACGATTTTAAAACCGTATACTGTGTCAGTTTTAT
TATTTTTTTCTTAACATGTCTTTATGTTGAGTGACTGTTGTGTGCCTGGTGTCATGGGGAGAGA
GGCAAGTAGGAAAATGATGTTGCACTGCTGATTTCAAAAAGATCTGGCAAACAAATCCTACAAA
GACTTGTTTTTCATTTCAATAAACACAATCTATATTAGTACAA

hide sequence

RefSeq Acc Id:

XM_006233357 ⟹ XP_006233419

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	224,256,273 - 224,319,326 (+)	NCBI
Rnor_6.0	2	241,029,254 - 241,092,584 (+)	NCBI
Rnor_5.0	2	259,584,747 - 259,648,098 (+)	NCBI

Sequence:

show sequence

GGCTAGCAACTCCTCCATGTCAACTTGCCAAGCCCACAGCCAGTTCCGAGAGGGTCCAGCAGCG
TAGACGCGGGAACCTGGGGACCCGGAGGGAGCGTTTCTTTGCAGCTCCTTGGGGGCTGGAGGCT
ACAGTCCCAACCCTTTCCACGTTGCTGCGGCGGGAAAATAAAGCCCTCAGACAGGAAGAGGAGT
TGGGGTTGCTCAGTCAGAGAGGATTTAGTTCCCCGAAGTGTGGCGCGGTTGGGGCTTTATATCC
GGGACAAGCGAGTGTCACCTCACTGCTCCGCAGGAGGCCCGGAGAGGCCACACTGCCTACCGTC
CTCCTGGCTGTGGTACCTCTTCAATGCCCCGAAGGTCTGAGGCTGCAGAGGAGCGGGGGCACCG
AGCTTCTCGCTAACTGGGGCAGGCAGTGACGTGAGACCGGCGGACCTCCCACCCCCACCCTAAG
GGCACCGACACCCGGGCACTCGCTCGGATCCCTGCATCCGCTAGCTCCGGAGCTGCGCGCTCCA
CGATGGCTCCGGGCCGGGCAGTGGCCGGGCTGCTGCTACTGGCGGCCACCGGCCTGGGACGCCC
CTCGGAGGGGCCGGAGCTCGCCTTCACTGAGGATGTGCTGAGAGTGTTCGGCGCCAACCAGAGC
CTGTCGGCCGCGCAGCTGGGGCGCCTGCTGGAGCGCCTGGGGGCTGCACCCCAGCAGGGAGCGC
TGGAGCTGGGCCAGCTCCACTTCAACCAGTGTCTGTCAGCGGAAGACATCTTTTCTCTTCATGG
TTTCTCAAACGTCACCCAGATAACCAGCTCGAACTTCACTGCCATCTGCCCTGCGATCTTACAG
CAGCTGAACTTTCATCCCTGTGAGGATCCACAGAAGCACAGCGTAAAGCCCAGTTTTTCCGAAG
TCTGGGGCTATGGATTCTTGTCAGTGACAATCATCAATTTGGCCTCTCTCCTGGGATTGATTTT
AACCCCCTTGATAAAGAAGTCGTATTTCCCCAAGATTTTGACTTATTTTGTGGGGCTGGCTATT
GGGACCCTTTTCTCAAATGCCATTTTCCAGCTTATTCCAGAGGCATTTGGATTTAATCCCAAAA
TTGACAATTATGTTGAAAAGGCAGTTGCTGTGTTTGGTGGATTTTACATGCTTTTCTTTGTTGA
AAGAACACTTAAGATGCTACTGAAAACGTACGGCCAGAATGACCATACTCACTTCAGGAATGAT
GACTTCGGTTCTAAAGAAAAAGCCCATCAACCCAAAACGTTGCCATTACCTCCTGTCAATGGAG
TGACATGCTATGCCAACCCCGCTGTCACTGAGCCTAATGGACACATCCACTTCGACACTGTCAG
TGTTGTGTCCCTGCAGGATGGAAAAGCAGAGTCAAGTTCATGCACCTGTTTGAAGGGGCCCAAA
CTGTCAGAAATAGGAACGATTGCTTGGATGATCACGCTCTGTGATGCCCTTCACAATTTCATTG
ATGGCTTGGCGATCGGGGCATCCTATACTCTGTCTCTTCTTCAAGGACTCAGTACTTCCATAGC
GATCCTGTGTGAGGAGTTTCCTCATGAGTTAGGGGACTTTGTGATCTTGCTCAATGCAGGGATG
AGCACTCGGCAAGCCTTGCTGTTTAACTTCCTCTCTGCATGTTCCTGCTACGTTGGGCTTGCTT
TCGGCATTTTGGTGGGCAACAACTTTGCTCCAAATATTATATTTGCACTTGCTGGAGGCATGTT
CCTTTACATTTCTCTGGCAGATATGTTTCCAGAGATGAACGACATGCTGAGAGAAAAAGTAACT
GGAAGACAAACGGACTTCACCTTCTTCATGATCCAGAACGCAGGGATGTTAACCGGATTCACTG
CCATCTTGCTCATCACCTTGTACGCAGGGGACATCGAATTGCAGTAGCTGGGAGTATGACGTCA
GCGCGGCAAGGCATTTAATAAACAACAACACAGAAGAAACATCTCCATAGGGAATTTTTTTAAA
AAAGTGTATCCTATTTAGTTAAAAGAGATTTTTTTTTTAAATTTTCAACTAGAGGCTAAGAAAT
CTAATGACTGGTTTCAGACACGTAGAATAGGTGAAATTTGTTGTTAAAAATTTCTTTAAAAGGT
TTTCGGTTTCAGTCTGAAATGGCTGGTGTATGGGGCCTTTGGTAAATACCTGTTTTTCAATATT
TTATGCCTATTAGAAAATTATCATGAAGCAAACACATGCATTCAGTAGCAGACATACAGACCCA
GAGAAAAACACAATCTGAGTCATGCAAGGCTTTAGAACTTGGTTGGATTAAACACACACACACA
CACACACACACACACACACACACACACACACACACACACACGTGTTTTCAGGGTGGTTTTCTTC
CGATTAATGTGTTCGTCTGCTTTTAAAGGCAGGTGCTTCAAATGTGGAAGGAAATCAAAACAGT
TCCAGTGCATGCAGGAAGGATTCCAGTGCCTTAATGAACCCCAGAGAGATTGTGCACAGCGTTT
GTTCAGCTTTTTGTCTCAGTTGGCGACCTGTAGGATTGTTTTGAAAGCTATCCCAAAGTAACAT
GAATTAGGAAAGGATGAGAGTCTTGCTAGCCAGGTGAAGCTTGGGCTTAGTGCTTGGTCCCTGA
GTATATAAGCTTGAACACACTCTGCAGAAGACCAGAATTTGCTGTGCTGTGACTTAGGTTGTGG
TTCCAGACAACAGAAATGGCCGAGGAGTAAGACTGGTCAGAACGCAGTCGTGCCGTGCTCTGGG
ATTGCTTTGTAAGGGTGAAGAATGTGTTGGGTGGGAGAGAGAAATTGAATATAATTTTGAGCAA
TTTACTTTTTTAAAGGTGAGCATAATTATTTAGCAGGGAGGATTTCAATAAATGCAAAATAACA
GCTGGGCTGGGCTGTGTCAGAGACTGATGGTGGAGGAAGCGTGTGTTCATTAGGGGTGACTGAC
AGTCAGAAACATCTTCTTTTATGCCCAGCATACTTTGTTCCCATATGCTATACCTTTGGATGGA
AAACACTCAACATACTGTGCTTATTTTTCTACCTTTGGTAAAACACAGAGCTCGCTGAGTTTTT
GAGCAGGCTGTAGACAATTAGTCTGAATTGAACATCCCAATCTCAATTCACACTCCCAAGGAAC
CCAAAAGAGATGATTTGACAGTGATGAGGATGATTAATAGAACACAACTTATCCCAGGATTGTG
TTTCCCTATAAGCCAAAACACATTTTCATGTAAGAACAATGCAAACTCGATAAACGTTAACATA
TATGTTTGTGTGTTTCACTCTATGACTGACAATTAAAACTTATTTGACCAGACAGTAAACGATT
TTAAAACCGTATACTGTGTCAGTTTTATTATTTTTTTCTTAACATGTCTTTATGTTGAGTGACT
GTTGTGTGCCTGGTGTCATGGGGAGAGAGGCAAGTAGGAAAATGATGTTGCACTGCTGATTTCA
AAAAGATCTGGCAAACAAATCCTACAAAGACTTGTTTTTCATTTCAATAAACACAATCTATATT
AGTACAA

hide sequence

RefSeq Acc Id:

XM_017590787 ⟹ XP_017446276

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	224,255,837 - 224,319,326 (+)	NCBI
Rnor_6.0	2	241,028,851 - 241,092,584 (+)	NCBI

Sequence:

show sequence

GTTCATTTTTGAGACAATGCAAGGGGCTCAAGACACCGTTCCAGGAAGCTGATTCCATGGAGGT
CACCAAAAAAAGTGGGCCGGGACACCAGAAAGGGGTCTAGGGATCCCACCGTGGAGGTGGGCTT
CAGGGAGCAGGCATCACAGTGGCTGGGATGGCAGACAGAGAGGCTCCGCAGGAGGCCCGGAGAG
GCCACACTGCCTACCGTCCTCCTGGCTGTGGTACCTCTTCAATGCCCCGAAGGTCTGAGGCTGC
AGAGGAGCGGGGGCACCGAGCTTCTCGCTAACTGGGGCAGGCAGTGACGTGAGACCGGCGGACC
TCCCACCCCCACCCTAAGGGCACCGACACCCGGGCACTCGCTCGGATCCCTGCATCCGCTAGCT
CCGGAGCTGCGCGCTCCACGATGGCTCCGGGCCGGGCAGTGGCCGGGCTGCTGCTACTGGCGGC
CACCGGCCTGGGACGCCCCTCGGAGGGGCCGGAGCTCGCCTTCACTGAGGATGTGCTGAGAGTG
TTCGGCGCCAACCAGAGCCTGTCGGCCGCGCAGCTGGGGCGCCTGCTGGAGCGCCTGGGGGCTG
CACCCCAGCAGGGAGCGCTGGAGCTGGGCCAGCTCCACTTCAACCAGTGTCTGTCAGCGGAAGA
CATCTTTTCTCTTCATGGTTTCTCAAACGTCACCCAGATAACCAGCTCGAACTTCACTGCCATC
TGCCCTGCGATCTTACAGCAGCTGAACTTTCATCCCTGTGAGGATCCACAGAAGCACAGCGTAA
AGCCCAGTTTTTCCGAAGTCTGGGGCTATGGATTCTTGTCAGTGACAATCATCAATTTGGCCTC
TCTCCTGGGATTGATTTTAACCCCCTTGATAAAGAAGTCGTATTTCCCCAAGATTTTGACTTAT
TTTGTGGGGCTGGCTATTGGGACCCTTTTCTCAAATGCCATTTTCCAGCTTATTCCAGAGGCAT
TTGGATTTAATCCCAAAATTGACAATTATGTTGAAAAGGCAGTTGCTGTGTTTGGTGGATTTTA
CATGCTTTTCTTTGTTGAAAGAACACTTAAGATGCTACTGAAAACGTACGGCCAGAATGACCAT
ACTCACTTCAGGAATGATGACTTCGGTTCTAAAGAAAAAGCCCATCAACCCAAAACGTTGCCAT
TACCTCCTGTCAATGGAGTGACATGCTATGCCAACCCCGCTGTCACTGAGCCTAATGGACACAT
CCACTTCGACACTGTCAGTGTTGTGTCCCTGCAGGATGGAAAAGCAGAGTCAAGTTCATGCACC
TGTTTGAAGGGGCCCAAACTGTCAGAAATAGGAACGATTGCTTGGATGATCACGCTCTGTGATG
CCCTTCACAATTTCATTGATGGCTTGGCGATCGGGGCATCCTATACTCTGTCTCTTCTTCAAGG
ACTCAGTACTTCCATAGCGATCCTGTGTGAGGAGTTTCCTCATGAGTTAGGGGACTTTGTGATC
TTGCTCAATGCAGGGATGAGCACTCGGCAAGCCTTGCTGTTTAACTTCCTCTCTGCATGTTCCT
GCTACGTTGGGCTTGCTTTCGGCATTTTGGTGGGCAACAACTTTGCTCCAAATATTATATTTGC
ACTTGCTGGAGGCATGTTCCTTTACATTTCTCTGGCAGATATGTTTCCAGAGATGAACGACATG
CTGAGAGAAAAAGTAACTGGAAGACAAACGGACTTCACCTTCTTCATGATCCAGAACGCAGGGA
TGTTAACCGGATTCACTGCCATCTTGCTCATCACCTTGTACGCAGGGGACATCGAATTGCAGTA
GCTGGGAGTATGACGTCAGCGCGGCAAGGCATTTAATAAACAACAACACAGAAGAAACATCTCC
ATAGGGAATTTTTTTAAAAAAGTGTATCCTATTTAGTTAAAAGAGATTTTTTTTTTAAATTTTC
AACTAGAGGCTAAGAAATCTAATGACTGGTTTCAGACACGTAGAATAGGTGAAATTTGTTGTTA
AAAATTTCTTTAAAAGGTTTTCGGTTTCAGTCTGAAATGGCTGGTGTATGGGGCCTTTGGTAAA
TACCTGTTTTTCAATATTTTATGCCTATTAGAAAATTATCATGAAGCAAACACATGCATTCAGT
AGCAGACATACAGACCCAGAGAAAAACACAATCTGAGTCATGCAAGGCTTTAGAACTTGGTTGG
ATTAAACACACACACACACACACACACACACACACACACACACACACACACACACACACGTGTT
TTCAGGGTGGTTTTCTTCCGATTAATGTGTTCGTCTGCTTTTAAAGGCAGGTGCTTCAAATGTG
GAAGGAAATCAAAACAGTTCCAGTGCATGCAGGAAGGATTCCAGTGCCTTAATGAACCCCAGAG
AGATTGTGCACAGCGTTTGTTCAGCTTTTTGTCTCAGTTGGCGACCTGTAGGATTGTTTTGAAA
GCTATCCCAAAGTAACATGAATTAGGAAAGGATGAGAGTCTTGCTAGCCAGGTGAAGCTTGGGC
TTAGTGCTTGGTCCCTGAGTATATAAGCTTGAACACACTCTGCAGAAGACCAGAATTTGCTGTG
CTGTGACTTAGGTTGTGGTTCCAGACAACAGAAATGGCCGAGGAGTAAGACTGGTCAGAACGCA
GTCGTGCCGTGCTCTGGGATTGCTTTGTAAGGGTGAAGAATGTGTTGGGTGGGAGAGAGAAATT
GAATATAATTTTGAGCAATTTACTTTTTTAAAGGTGAGCATAATTATTTAGCAGGGAGGATTTC
AATAAATGCAAAATAACAGCTGGGCTGGGCTGTGTCAGAGACTGATGGTGGAGGAAGCGTGTGT
TCATTAGGGGTGACTGACAGTCAGAAACATCTTCTTTTATGCCCAGCATACTTTGTTCCCATAT
GCTATACCTTTGGATGGAAAACACTCAACATACTGTGCTTATTTTTCTACCTTTGGTAAAACAC
AGAGCTCGCTGAGTTTTTGAGCAGGCTGTAGACAATTAGTCTGAATTGAACATCCCAATCTCAA
TTCACACTCCCAAGGAACCCAAAAGAGATGATTTGACAGTGATGAGGATGATTAATAGAACACA
ACTTATCCCAGGATTGTGTTTCCCTATAAGCCAAAACACATTTTCATGTAAGAACAATGCAAAC
TCGATAAACGTTAACATATATGTTTGTGTGTTTCACTCTATGACTGACAATTAAAACTTATTTG
ACCAGACAGTAAACGATTTTAAAACCGTATACTGTGTCAGTTTTATTATTTTTTTCTTAACATG
TCTTTATGTTGAGTGACTGTTGTGTGCCTGGTGTCATGGGGAGAGAGGCAAGTAGGAAAATGAT
GTTGCACTGCTGATTTCAAAAAGATCTGGCAAACAAATCCTACAAAGACTTGTTTTTCATTTCA
ATAAACACAATCTATATTAGTACAA

hide sequence

RefSeq Acc Id:

XM_039102102 ⟹ XP_038958030

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	224,171,787 - 224,319,326 (+)	NCBI

RefSeq Acc Id:

XM_039102104 ⟹ XP_038958032

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	224,256,064 - 224,319,326 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001011952	(Get FASTA)	NCBI Sequence Viewer
	XP_006233418	(Get FASTA)	NCBI Sequence Viewer
	XP_006233419	(Get FASTA)	NCBI Sequence Viewer
	XP_017446276	(Get FASTA)	NCBI Sequence Viewer
	XP_038958030	(Get FASTA)	NCBI Sequence Viewer
	XP_038958032	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH89844	(Get FASTA)	NCBI Sequence Viewer
	EDL82275	(Get FASTA)	NCBI Sequence Viewer
	Q5FVQ0	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_001011952 ⟸ NM_001011952
- Peptide Label:	precursor
- UniProtKB:	Q5FVQ0 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MAPGRAVAGLLLLAATGLGRPSEGPELAFTEDVLRVFGANQSLSAAQLGRLLERLGAAPQQGAL ELGQLHFNQCLSAEDIFSLHGFSNVTQITSSNFTAICPAILQQLNFHPCEDPQKHSVKPSFSEV WGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTYFVGLAIGTLFSNAIFQLIPEAFGFNPKI DNYVEKAVAVFGGFYMLFFVERTLKMLLKTYGQNDHTHFRNDDFGSKEKAHQPKTLPLPPVNGV TCYANPAVTEPNGHIHFDTVSVVSLQDGKAESSSCTCLKGPKLSEIGTIAWMITLCDALHNFID GLAIGASYTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAF GILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLREKVTGRQTDFTFFMIQNAGMLTGFTA ILLITLYAGDIELQ hide sequence

RefSeq Acc Id:	XP_006233418 ⟸ XM_006233356
- Peptide Label:	isoform X1
- UniProtKB:	Q5FVQ0 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MAPGRAVAGLLLLAATGLGRPSEGPELAFTEDVLRVFGANQSLSAAQLGRLLERLGAAPQQGAL ELGQLHFNQCLSAEDIFSLHGFSNVTQITSSNFTAICPAILQQLNFHPCEDPQKHSVKPSFSEV WGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTYFVGLAIGTLFSNAIFQLIPEAFGFNPKI DNYVEKAVAVFGGFYMLFFVERTLKMLLKTYGQNDHTHFRNDDFGSKEKAHQPKTLPLPPVNGV TCYANPAVTEPNGHIHFDTVSVVSLQDGKAESSSCTCLKGPKLSEIGTIAWMITLCDALHNFID GLAIGASYTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAF GILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLREKVTGRQTDFTFFMIQNAGMLTGFTA ILLITLYAGDIELQ hide sequence

RefSeq Acc Id:	XP_006233419 ⟸ XM_006233357
- Peptide Label:	isoform X1
- UniProtKB:	Q5FVQ0 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MAPGRAVAGLLLLAATGLGRPSEGPELAFTEDVLRVFGANQSLSAAQLGRLLERLGAAPQQGAL ELGQLHFNQCLSAEDIFSLHGFSNVTQITSSNFTAICPAILQQLNFHPCEDPQKHSVKPSFSEV WGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTYFVGLAIGTLFSNAIFQLIPEAFGFNPKI DNYVEKAVAVFGGFYMLFFVERTLKMLLKTYGQNDHTHFRNDDFGSKEKAHQPKTLPLPPVNGV TCYANPAVTEPNGHIHFDTVSVVSLQDGKAESSSCTCLKGPKLSEIGTIAWMITLCDALHNFID GLAIGASYTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAF GILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLREKVTGRQTDFTFFMIQNAGMLTGFTA ILLITLYAGDIELQ hide sequence

RefSeq Acc Id:	XP_017446276 ⟸ XM_017590787
- Peptide Label:	isoform X1
- UniProtKB:	Q5FVQ0 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MAPGRAVAGLLLLAATGLGRPSEGPELAFTEDVLRVFGANQSLSAAQLGRLLERLGAAPQQGAL ELGQLHFNQCLSAEDIFSLHGFSNVTQITSSNFTAICPAILQQLNFHPCEDPQKHSVKPSFSEV WGYGFLSVTIINLASLLGLILTPLIKKSYFPKILTYFVGLAIGTLFSNAIFQLIPEAFGFNPKI DNYVEKAVAVFGGFYMLFFVERTLKMLLKTYGQNDHTHFRNDDFGSKEKAHQPKTLPLPPVNGV TCYANPAVTEPNGHIHFDTVSVVSLQDGKAESSSCTCLKGPKLSEIGTIAWMITLCDALHNFID GLAIGASYTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLSACSCYVGLAF GILVGNNFAPNIIFALAGGMFLYISLADMFPEMNDMLREKVTGRQTDFTFFMIQNAGMLTGFTA ILLITLYAGDIELQ hide sequence

RefSeq Acc Id:

ENSRNOP00000030977 ⟸ ENSRNOT00000033413

RefSeq Acc Id:	XP_038958030 ⟸ XM_039102102
- Peptide Label:	isoform X1
- UniProtKB:	Q5FVQ0 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038958032 ⟸ XM_039102104
- Peptide Label:	isoform X1
- UniProtKB:	Q5FVQ0 (UniProtKB/Swiss-Prot)

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5FVQ0-F1-model_v2	AlphaFold	Q5FVQ0	1-462	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13691772

Promoter ID:

EPDNEW_R2297

Type:

initiation region

Name:

Slc39a8_2

Description:

solute carrier family 39 member 8

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R2298

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	2	241,029,614 - 241,029,674	EPDNEW

RGD ID:

13691773

Promoter ID:

EPDNEW_R2298

Type:

initiation region

Name:

Slc39a8_1

Description:

solute carrier family 39 member 8

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R2297

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	2	241,029,883 - 241,029,943	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308236	AgrOrtholog
BioCyc Gene	G2FUF-51125	BioCyc
Ensembl Genes	ENSRNOG00000012508	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein	ENSRNOP00000030977	ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000033413	ENTREZGENE, UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7368889	IMAGE-MGC_LOAD
InterPro	ZIP	UniProtKB/Swiss-Prot
KEGG Report	rno:295455	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:108852	IMAGE-MGC_LOAD
NCBI Gene	295455	ENTREZGENE
Pfam	Zip	UniProtKB/Swiss-Prot
PhenoGen	Slc39a8	PhenoGen
UniProt	Q5FVQ0	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Slc39a8	solute carrier family 39 member 8	LOC108350117	uncharacterized LOC108350117	Data Merged	737654	PROVISIONAL
2016-08-02	LOC108350117	uncharacterized LOC108350117			Symbol and Name status set to provisional	70820	PROVISIONAL
2016-02-24	Slc39a8	solute carrier family 39 member 8	Slc39a8	solute carrier family 39 (zinc transporter), member 8	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2009-12-16	Slc39a8	solute carrier family 39 (zinc transporter), member 8	Slc39a8	solute carrier family 39 (metal ion transporter), member 8	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Slc39a8	solute carrier family 39 (metal ion transporter), member 8	Slc39a8_predicted	solute carrier family 39 (metal ion transporter), member 8 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Slc39a8_predicted	solute carrier family 39 (metal ion transporter), member 8 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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