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Gene: Nupr1 (nuclear protein 1, transcriptional regulator) Rattus norvegicus
Symbol: Nupr1
Name: nuclear protein 1, transcriptional regulator
RGD ID: 69363
Description: Predicted to have DNA binding activity; chromatin binding activity; and molecular function regulator. Involved in several processes, including negative regulation of DNA-binding transcription factor activity; negative regulation of autophagy; and regulation of apoptotic process. Predicted to localize to nucleoplasm; perinuclear region of cytoplasm; and protein-DNA complex. Orthologous to human NUPR1 (nuclear protein 1, transcriptional regulator); INTERACTS WITH 1-naphthyl isothiocyanate; 1-nitropropane; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: candidate of metastasis 1; LOC100912108; nuclear protein 1; nuclear protein 1-like; nuclear protein, transcriptional regulator, 1; nuclear proten 1; nuclear transcriptional regulator protein 1; p8
Homo sapiens (human) : NUPR1 (nuclear protein 1, transcriptional regulator)  HGNC  Alliance
Mus musculus (house mouse) : Nupr1 (nuclear protein transcription regulator 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nupr1 (nuclear protein 1, transcriptional regulator)
Pan paniscus (bonobo/pygmy chimpanzee) : NUPR1 (nuclear protein 1, transcriptional regulator)
Canis lupus familiaris (dog) : NUPR1 (nuclear protein 1, transcriptional regulator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nupr1 (nuclear protein 1, transcriptional regulator)
Sus scrofa (pig) : NUPR1 (nuclear protein 1, transcriptional regulator)
Chlorocebus sabaeus (African green monkey) : NUPR1 (nuclear protein 1, transcriptional regulator)
Heterocephalus glaber (naked mole-rat) : Nupr1 (nuclear protein 1, transcriptional regulator)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Note: This single-copy gene is duplicated in the RGSC5.0 assembly; GeneID:100912108 represents the intended location for the rat Nupr1 gene while GeneID:113900 is most likely an artifact in the RGSC5.0 assembly, based on syntenic gene analysis. [17 Jun 2014]
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01194,767,484 - 194,769,519 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1194,767,474 - 194,769,524 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01205,021,877 - 205,023,912 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41185,770,310 - 185,772,313 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1178,871,291 - 178,873,326 (-)NCBICelera
Cytogenetic Map1q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Nupr1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69363
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.