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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69363
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nupr1
Name: nuclear protein 1, transcriptional regulator
Acc ID: CHEBI:582124
Term: myriocin
Definition: An amino acid-based antibiotic derived from certain thermophilic fungi; acts as a potent inhibitor of serine palmitoyltransferase, the first step in sphingosine biosynthesis. Myriocin also possesses immunosuppressant activity.
Chemical ID: MESH:C001996
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nupr1multiple interactionsEXP 6480464CTDthermozymocidin inhibits the reaction [Dronabinol results in increased expression of NUPR1 mRNA]

PMID:16616335
Nupr1multiple interactionsISORGD:7369586480464CTDthermozymocidin inhibits the reaction [Dronabinol results in increased expression of NUPR1 mRNA]

PMID:16818650
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