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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69363
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nupr1
Name: nuclear protein 1, transcriptional regulator
Acc ID: CHEBI:3723
Term: citalopram
Definition: A racemate comprising equimolar amounts of (R)-citalopram and its enantiomer, escitalopram. It is used as an antidepressant, although only escitalopram is active.
Chemical ID: MESH:D015283
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nupr1increases expressionISONUPR1 (Homo sapiens)6480464CTDCitalopram results in increased expression of NUPR1 mRNAPMID:17567588
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