Dgat2 (diacylglycerol O-acyltransferase 2)

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Gene: Dgat2 (diacylglycerol O-acyltransferase 2) Rattus norvegicus

Analyze

Symbol:

Dgat2

Name:

diacylglycerol O-acyltransferase 2

RGD ID:

620329

Description:

Enables diacylglycerol O-acyltransferase activity. Involved in several processes, including bile acid signaling pathway; positive regulation of gluconeogenesis; and regulation of lipid metabolic process. Located in intracellular membrane-bounded organelle. Used to study fatty liver disease. Biomarker of chronic kidney disease; non-alcoholic fatty liver disease; and premature menopause. Human ortholog(s) of this gene implicated in non-alcoholic fatty liver disease. Orthologous to human DGAT2 (diacylglycerol O-acyltransferase 2); PARTICIPATES IN bile acid signaling pathway; glycerolipid metabolic pathway; INTERACTS WITH (+)-schisandrin B; (R)-lipoic acid; 2,2',4,4'-Tetrabromodiphenyl ether.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

acyl-CoA retinol O-fatty-acyltransferase; ARAT; diacylglycerol O-acyltransferase homolog 2 (mouse); diglyceride acyltransferase 2; MGC108863; retinol O-fatty-acyltransferase

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DGAT2 (diacylglycerol O-acyltransferase 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Dgat2 (diacylglycerol O-acyltransferase 2)	HGNC	Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Dgat2 (diacylglycerol O-acyltransferase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	DGAT2 (diacylglycerol O-acyltransferase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	DGAT2 (diacylglycerol O-acyltransferase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Dgat2 (diacylglycerol O-acyltransferase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	DGAT2 (diacylglycerol O-acyltransferase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	DGAT2 (diacylglycerol O-acyltransferase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Dgat2 (diacylglycerol O-acyltransferase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	DGAT2 (diacylglycerol O-acyltransferase 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Mus musculus (house mouse):	Dgat2 (diacylglycerol O-acyltransferase 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Danio rerio (zebrafish):	dgat2 (diacylglycerol O-acyltransferase 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Drosophila melanogaster (fruit fly):	CG1941	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Saccharomyces cerevisiae (baker's yeast):	DGA1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	K07B1.4	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|TreeFam)
Caenorhabditis elegans (roundworm):	dgtr-1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|TreeFam)
Drosophila melanogaster (fruit fly):	CG1946	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Drosophila melanogaster (fruit fly):	Dgat2	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	153,454,078 - 153,484,432 (-)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	1	153,454,080 - 153,484,428 (-)	Ensembl
Rnor_6.0	1	164,113,459 - 164,143,818 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	164,113,459 - 164,143,818 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	170,316,041 - 170,346,352 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	156,447,588 - 156,478,740 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	1	156,529,080 - 156,531,888 (-)	NCBI
Celera	1	151,539,454 - 151,569,146 (-)	NCBI		Celera
Cytogenetic Map	1	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Chemical and Drug Induced Liver Injury (ISO)

cholestasis (ISO)

chronic kidney disease (IEP)

fatty liver disease (IMP)

intellectual disability (ISO)

Knee Osteoarthritis (ISO)

non-alcoholic fatty liver disease (IEP,ISO)

premature menopause (IEP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(R)-lipoic acid (EXP)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

3,3',4,4',5-pentachlorobiphenyl (EXP,ISO)

3,3',4,4'-tetrachlorobiphenyl (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

5-(2-chloroethyl)-4-methylthiazole (ISO)

8-Br-cAMP (ISO)

acetamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amiodarone (ISO)

ammonium chloride (EXP)

aristolochic acid (ISO)

atrazine (ISO)

avobenzone (ISO)

benzene (ISO)

benzene-1,2,4-triol (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

benzylpenicillin (ISO)

beta-naphthoflavone (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

calcitriol (ISO)

carbendazim (ISO)

carbon nanotube (ISO)

chlorothalonil (ISO)

chlorpyrifos (EXP)

cholesterol (ISO)

choline (ISO)

chrysene (ISO)

clofibrate (EXP,ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

dexamethasone (EXP,ISO)

Diallyl sulfide (ISO)

dieldrin (ISO)

dioscin (EXP,ISO)

diuron (EXP)

dorsomorphin (EXP)

endosulfan (EXP,ISO)

erythromycin A (ISO)

ethanol (EXP,ISO)

farnesol (ISO)

flutamide (EXP)

fructose (ISO)

genistein (ISO)

gentamycin (EXP)

graphite (ISO)

GW 4064 (ISO)

GW 7647 (ISO)

hydrogen cyanide (ISO)

hydrogen peroxide (ISO)

Indeno[1,2,3-cd]pyrene (ISO)

indometacin (ISO)

ketamine (EXP)

L-methionine (ISO)

lipoic acid (EXP)

mangiferin (EXP)

menadione (ISO)

methotrexate (ISO)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

N-acetyl-L-cysteine (ISO)

N-methyl-4-phenylpyridinium (ISO)

nickel atom (ISO)

nicotinic acid (ISO)

nimesulide (EXP)

nitrofen (EXP)

O-methyleugenol (ISO)

obeticholic acid (ISO)

oleic acid (ISO)

oxaliplatin (EXP)

paracetamol (EXP,ISO)

perfluorohexanesulfonic acid (ISO)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

pioglitazone (ISO)

pirinixic acid (ISO)

potassium cyanide (ISO)

potassium dichromate (ISO)

procymidone (ISO)

propamocarb (ISO)

propiconazole (ISO)

quercetin (ISO)

rebaudioside A (ISO)

rifaximin (ISO)

S-butyl-DL-homocysteine (S,R)-sulfoximine (EXP)

silicon dioxide (ISO)

sodium arsenite (ISO)

steviol (ISO)

stevioside (ISO)

sucrose (ISO)

sulforaphane (ISO)

tamoxifen (ISO)

tectoridin (ISO)

tert-butyl hydroperoxide (ISO)

testosterone (EXP,ISO)

tetrachloromethane (EXP)

tetracycline (ISO)

tetraphene (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

topotecan (EXP)

tributyl phosphate (ISO)

tributylstannane (ISO)

trichloroethene (ISO)

trichostatin A (ISO)

triclosan (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

Tris(2,3-dibromopropyl) phosphate (ISO)

tris(2-butoxyethyl) phosphate (ISO)

trovafloxacin (EXP)

urethane (ISO)

valdecoxib (EXP)

valproic acid (ISO)

vancomycin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

bile acid signaling pathway (IEP)

cellular lipid metabolic process (IEA)

cellular response to oleic acid (ISO)

cellular triglyceride homeostasis (ISO)

cholesterol homeostasis (ISO)

diacylglycerol biosynthetic process (ISO,ISS)

diacylglycerol metabolic process (IBA,IMP,ISO)

fat pad development (ISO)

fatty acid homeostasis (ISO)

glycerol metabolic process (IEA)

lipid metabolic process (IBA)

lipid storage (ISO)

long-chain fatty-acyl-CoA metabolic process (ISO)

low-density lipoprotein particle clearance (ISO)

monoacylglycerol biosynthetic process (ISO,ISS)

negative regulation of fatty acid oxidation (IMP)

positive regulation of gluconeogenesis (IMP)

positive regulation of triglyceride biosynthetic process (IMP)

regulation of cholesterol metabolic process (IMP)

regulation of lipoprotein metabolic process (IMP)

regulation of plasma lipoprotein particle levels (ISO)

retinol metabolic process (IEA)

triglyceride biosynthetic process (IBA,IEA,ISO,ISS)

Cellular Component

cytosol (IEA,ISO)

endoplasmic reticulum (ISO)

endoplasmic reticulum membrane (IBA,IEA,ISO,ISS)

integral component of endoplasmic reticulum membrane (ISO)

integral component of membrane (IEA,ISO)

intracellular membrane-bounded organelle (IDA,ISO)

lipid droplet (ISO,ISS)

membrane (ISO)

mitochondrion (ISO)

perinuclear endoplasmic reticulum membrane (ISO,ISS)

perinuclear region of cytoplasm (ISO)

Molecular Function

2-acylglycerol O-acyltransferase activity (ISO)

diacylglycerol O-acyltransferase activity (IDA,ISO)

O-acyltransferase activity (IEA)

protein binding (ISO)

protein homodimerization activity (ISO)

retinol O-fatty-acyltransferase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

bile acid signaling pathway (IEP)

glycerolipid metabolic pathway (IEA)

References

References - curated


1.	Choi CS, etal., J Biol Chem. 2007 Aug 3;282(31):22678-88. Epub 2007 May 27.
2.	Côté I, etal., Br J Nutr. 2014 Nov 28;112(10):1592-600. doi: 10.1017/S0007114514002517. Epub 2014 Sep 29.
3.	Gandhi R, etal., J Rheumatol. 2011 Sep;38(9):1966-72. Epub 2011 Jul 15.
4.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5.	GOA data from the GO Consortium
6.	Jin K, etal., Nephrol Dial Transplant. 2013 Feb;28(2):313-20. doi: 10.1093/ndt/gfs350. Epub 2012 Oct 8.
7.	MGD data from the GO Consortium
8.	Monetti M, etal., Cell Metab. 2007 Jul;6(1):69-78.
9.	NCBI rat LocusLink and RefSeq merged data July 26, 2002
10.	Pipeline to import KEGG annotations from KEGG into RGD
11.	RGD automated data pipeline
12.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13.	RGD automated import pipeline for gene-chemical interactions
14.	Seo M, etal., Dig Dis Sci. 2013 Dec;58(12):3534-44. doi: 10.1007/s10620-013-2879-3. Epub 2013 Oct 29.
15.	Waterman IJ, etal., J Lipid Res 2002 Sep;43(9):1555-62.

Additional References at PubMed

PMID:11481335	PMID:12077311	PMID:12477932	PMID:14521909	PMID:14668353	PMID:15489334	PMID:18175806	PMID:18252207	PMID:18696335	PMID:19049983	PMID:21317108	PMID:21680734
PMID:24953780	PMID:25164810	PMID:27184406	PMID:28420705

Genomics

Comparative Map Data

Dgat2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	153,454,078 - 153,484,432 (-)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	1	153,454,080 - 153,484,428 (-)	Ensembl
Rnor_6.0	1	164,113,459 - 164,143,818 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	164,113,459 - 164,143,818 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	170,316,041 - 170,346,352 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	156,447,588 - 156,478,740 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	1	156,529,080 - 156,531,888 (-)	NCBI
Celera	1	151,539,454 - 151,569,146 (-)	NCBI		Celera
Cytogenetic Map	1	q32	NCBI

DGAT2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	75,768,778 - 75,801,534 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	11	75,759,512 - 75,801,535 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	75,479,823 - 75,512,579 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	75,157,456 - 75,190,225 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	11	75,157,455 - 75,190,225	NCBI
Celera	11	72,787,576 - 72,820,377 (+)	NCBI
Cytogenetic Map	11	q13.5	NCBI
HuRef	11	71,776,445 - 71,809,321 (+)	NCBI		HuRef
CHM1_1	11	75,363,395 - 75,396,193 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	75,698,501 - 75,731,257 (+)	NCBI

Dgat2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	98,802,870 - 98,831,920 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	7	98,802,865 - 98,831,926 (-)	Ensembl
GRCm38	7	99,153,663 - 99,182,713 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	99,153,658 - 99,182,719 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	106,302,173 - 106,331,223 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	7	99,028,855 - 99,057,905 (-)	NCBI			mm8
Celera	7	99,478,097 - 99,506,939 (-)	NCBI		Celera
Cytogenetic Map	7	E1	NCBI

Dgat2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955414	16,059,781 - 16,089,727 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955414	16,059,781 - 16,089,727 (-)	NCBI	ChiLan1.0	ChiLan1.0

DGAT2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	11	74,109,523 - 74,158,854 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	74,126,169 - 74,158,854 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	11	70,824,791 - 70,857,530 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

DGAT2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	21	22,833,659 - 22,850,300 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	21	22,834,518 - 22,851,260 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	21	22,599,527 - 22,636,714 (-)	NCBI
ROS_Cfam_1.0	21	23,036,854 - 23,073,838 (-)	NCBI
ROS_Cfam_1.0 Ensembl	21	23,036,854 - 23,069,245 (-)	Ensembl
UMICH_Zoey_3.1	21	22,835,850 - 22,868,136 (-)	NCBI
UNSW_CanFamBas_1.0	21	23,032,018 - 23,064,319 (-)	NCBI
UU_Cfam_GSD_1.0	21	22,949,639 - 22,986,269 (-)	NCBI

Dgat2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	62,914,608 - 62,944,920 (+)	NCBI
SpeTri2.0	NW_004936498	4,514,212 - 4,544,523 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DGAT2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	10,032,127 - 10,068,464 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	10,032,163 - 10,066,082 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	11,160,734 - 11,176,926 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DGAT2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	66,985,413 - 67,018,058 (+)	NCBI	ChlSab1.1		chlSab2
ChlSab1.1 Ensembl	1	66,985,466 - 67,021,182 (+)	Ensembl	ChlSab1.1		chlSab2
Vero_WHO_p1.0	NW_023666043	58,785,359 - 58,818,019 (-)	NCBI	Vero_WHO_p1.0

Dgat2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624817	1,386,764 - 1,418,300 (-)	Ensembl	HetGla_female_1.0		hetGla2
HetGla 1.0	NW_004624817	1,386,876 - 1,418,129 (-)	NCBI	HetGla_female_1.0		hetGla2

Position Markers

RH134485

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	153,454,184 - 153,454,370 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	164,113,564 - 164,113,749	NCBI	Rnor6.0
Rnor_5.0	1	170,316,146 - 170,316,331	UniSTS	Rnor5.0
RGSC_v3.4	1	156,447,693 - 156,447,878	UniSTS	RGSC3.4
Celera	1	151,539,559 - 151,539,744	UniSTS
RH 3.4 Map	1	1232.7	UniSTS
Cytogenetic Map	1	q32	UniSTS

RH139205

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	153,458,492 - 153,459,149 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	164,117,900 - 164,118,556	NCBI	Rnor6.0
Rnor_5.0	1	170,320,388 - 170,321,044	UniSTS	Rnor5.0
RGSC_v3.4	1	156,452,822 - 156,453,478	UniSTS	RGSC3.4
Celera	1	151,543,235 - 151,543,891	UniSTS
RH 3.4 Map	1	1233.6	UniSTS
Cytogenetic Map	1	q32	UniSTS

G42985

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	153,454,906 - 153,455,054 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	164,114,286 - 164,114,433	NCBI	Rnor6.0
Rnor_5.0	1	170,316,868 - 170,317,015	UniSTS	Rnor5.0
RGSC_v3.4	1	156,448,415 - 156,448,562	UniSTS	RGSC3.4
Celera	1	151,540,281 - 151,540,428	UniSTS
Cytogenetic Map	1	q32	UniSTS

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32356093	162846471	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32737458	199368955	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	49393172	159356837	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	49393289	199050459	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	81591954	219808434	Rat
724521	Uae1	Urinary albumin excretion QTL 1	3.8	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	90508614	173018436	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	90508614	180359386	Rat
1331793	Bp200	Blood pressure QTL 200	3.71601		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	94494440	172949803	Rat
1331751	Bp199	Blood pressure QTL 199	3.60022		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	94494440	181830018	Rat
1331749	Hrtrt11	Heart rate QTL 11	2.973		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	94494440	198211706	Rat
70209	Niddm23	Non-insulin dependent diabetes mellitus QTL 23	2.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	94494440	198324465	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	94642722	214537671	Rat
8655649	Arrd1	Age-related retinal degeneration QTL 1	4.89		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	100357752	183970443	Rat
1354591	Cm36	Cardiac mass QTL 36	4.1		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	102813953	201278233	Rat
1354615	Cm32	Cardiac mass QTL 32	5.2		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	102813953	201278233	Rat
1354606	Bp246	Blood pressure QTL 246	3.6		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	102813953	218753816	Rat
1300158	Bp173	Blood pressure QTL 173	3.48		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	1	115540693	185145286	Rat
7794788	Mcs32	Mammary carcinoma susceptibility QTL 32	2.61		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	1	115540693	238914717	Rat
631199	Cm23	Cardiac mass QTL 23	4.6	0.0004	heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	115585465	172949803	Rat
7421630	Bp362	Blood pressure QTL 362		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	118608292	241799120	Rat
2313060	Bss71	Bone structure and strength QTL 71	2.6	0.0001	long bone metaphysis morphology trait (VT:0000133)	tibia midshaft total cross-sectional area (CMO:0001715)	1	118944747	163944747	Rat
631205	Bp196	Blood pressure QTL 196	4	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	118944897	199050459	Rat
1598850	Bp297	Blood pressure QTL 297	2.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	121006655	166006655	Rat
1598866	Bp287	Blood pressure QTL 287	5.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	121006655	166006655	Rat
61442	Strs1	Sensitivity to stroke QTL 1	7.4		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	1	121767634	166767634	Rat
2293140	Bp313	Blood pressure QTL 313			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	121833674	166833674	Rat
631544	Bp84	Blood pressure QTL 84	5.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	123350408	181759564	Rat
1358189	Cstrr1	Cold stress response QTL 1		0.0001	catecholamine amount (VT:0010543)	urine norepinephrine level (CMO:0001629)	1	123350408	182418476	Rat
1641895	Bp298	Blood pressure QTL 298			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	123350408	182418476	Rat
1578770	Stresp23	Stress response QTL 23			kidney sympathetic nerve activity (VT:0004050)	stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)	1	123350408	182418476	Rat
631549	Bp89	Blood pressure QTL 89	5.7		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	123350581	201284552	Rat
634348	Bp138	Blood pressure QTL 138			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	125611501	168883176	Rat
9685799	Bp375	Blood pressure QTL 375			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	125611501	170611501	Rat
631654	Bp107	Blood pressure QTL 107			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	125611501	170611501	Rat
9685802	Bp376	Blood pressure QTL 376			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	126540680	171540680	Rat
738006	Anxrr14	Anxiety related response QTL 14	4	0.00035	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	130636910	175636910	Rat
738028	Anxrr12	Anxiety related response QTL 12	4.9	0.00001	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	130636910	175636910	Rat
631202	Gluco13	Glucose level QTL 13		0.0001	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	131763437	159756369	Rat
6893347	Bw98	Body weight QTL 98	0.2	0.53	body mass (VT:0001259)	body weight (CMO:0000012)	1	133680936	178680936	Rat
6893361	Bw104	Body weight QTL 104	0.59	0.27	body mass (VT:0001259)	body weight (CMO:0000012)	1	133680936	178680936	Rat
1558645	Bw55	Body weight QTL 55	3.2	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	1	133680936	178680936	Rat
631206	Niddm40	Non-insulin dependent diabetes mellitus QTL 40			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	136745990	163747690	Rat
71118	Thym1	Thymus enlargement QTL 1	10.17	0.001	thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	1	136829932	181829932	Rat
724550	Thym3	Thymus enlargement QTL 3	7.82	0.001	thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	1	136829932	181829932	Rat
631519	Pia11	Pristane induced arthritis QTL 11	5.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	136830018	181830018	Rat
1598853	Memor3	Memory QTL 3	4.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	1	143506580	212458660	Rat
61348	Bp30	Blood pressure QTL 30	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	144017057	197814409	Rat
70160	Bw18	Body weight QTL 18	5.7		body mass (VT:0001259)	body weight (CMO:0000012)	1	144267353	196383635	Rat
737828	Hcas3	Hepatocarcinoma susceptibility QTL 3	4.9		liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	1	144267353	222987745	Rat
2302378	Insul11	Insulin level QTL 11	3.25		blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	1	144267353	251128347	Rat
634315	Niddm45	Non-insulin dependent diabetes mellitus QTL 45	7.16		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	144267916	172949660	Rat
61379	Bp44	Blood pressure QTL 44	19.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	144267916	174133260	Rat
7771612	Cm80	Cardiac mass QTL 80	8.4		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	1	149448574	221264292	Rat
724531	Uae5	Urinary albumin excretion QTL 5	4		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	1	150700142	252085212	Rat
1578759	Uae30	Urinary albumin excretion QTL 30	3.3	0.003	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	150700247	252085048	Rat
1578778	Pur4	Proteinuria QTL 4	3.3	0.003	total urine protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	1	150700247	252085048	Rat
1354602	Bw35	Body weight QTL 35	12.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	201278233	Rat
1354620	Kidm19	Kidney mass QTL 19	4		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	151162512	201278233	Rat
1354634	Kidm12	Kidney mass QTL 12	3.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	1	151162512	201278233	Rat
1354636	Lmblg1	Limb length QTL 1	6.4		tibia length (VT:0004357)	tibia length (CMO:0000450)	1	151162512	201278233	Rat
1354610	Bw34	Body weight QTL 34	4.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	256448636	Rat
1354646	Kidm18	Kidney mass QTL 18	5.7		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	151162512	256448636	Rat
1354661	Bw33	Body weight QTL 33	5.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	256448636	Rat
1358886	Bp260	Blood pressure QTL 260	3.67		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	151162766	225824951	Rat
61343	Bp28	Blood pressure QTL 28			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	151646613	196646613	Rat
1549837	Hcar15	Hepatocarcinoma resistance QTL 15		0.05	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	153136852	260522016	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	358
Count of miRNA genes:	222
Interacting mature miRNAs:	255
Transcripts:	ENSRNOT00000022557
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	10	57	41	11	41	8	11	41	29	28	11	8
Low		33			8				33	6	13
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001012345	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006229733	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008759689	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101533	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101534	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AJ487787	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC089846	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000042	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000022557 ⟹ ENSRNOP00000022557

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	153,454,080 - 153,484,428 (-)	Ensembl
Rnor_6.0 Ensembl	1	164,113,459 - 164,143,818 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000081669 ⟹ ENSRNOP00000069294

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	153,454,080 - 153,482,804 (-)	Ensembl
Rnor_6.0 Ensembl	1	164,114,210 - 164,142,206 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000114431 ⟹ ENSRNOP00000088100

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	153,454,080 - 153,470,403 (-)	Ensembl

RefSeq Acc Id:

NM_001012345 ⟹ NP_001012345

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	153,454,080 - 153,484,412 (-)	NCBI
Rnor_6.0	1	164,113,459 - 164,143,818 (-)	NCBI
Rnor_5.0	1	170,316,041 - 170,346,352 (-)	NCBI
RGSC_v3.4	1	156,447,588 - 156,478,740 (-)	RGD
Celera	1	151,539,454 - 151,569,146 (-)	RGD

Sequence:

show sequence

GCCTAGGGTGGCAGCGGCTACCTACCTCGGATCTCGACCTGCTGCCACCACGGCCTGAGCGCTG
TCCCTCGGCTCCCGGAGCTCAGCGCGAAGCCCTGGCCCCGGCGGCTGGGGCATGGATCAGGGGC
GCTGCGTGAGGCGGCTTCCTGCACGGCCGTGACGTGCACCGGCTTCAGCATGAAGACCCTCATC
GCTGCCTACTCCGGGGTCCTGCGGGGTGAGCGTCGGGCCGAAGCTGCCCGCAGCGAGAACAAGA
ATAAAGGATCTGCCCTGTCACGCGAGGGGTCTGGGCGATGGGGCACTGGCTCCAGCATCCTCTC
GGCCCTCCAAGACATCTTCTCTGTCACCTGGCTCAACAGATCCAAGGTGGAAAAACACCTACAG
GTCATCTCAGTCCTACAGTGGGTCCTATCCTTCCTGGTGCTAGGAGTGGCCTGCAGTGTCATCC
TCATGTACACCTTCTGCACTGACTGCTGGCTGATAGCTGCTCTCTACTTCACCTGGCTGGCATT
TGACTGGAACACGCCCAAGAAAGGTGGCAGGAGATCACAGTGGGTGCGAAACTGGGCCGTGTGG
CGCTATTTTCGAGACTACTTTCCCATCCAGCTGGTGAAGACACACAACCTGCTGACCACCAGGA
ACTATATCTTTGGATACCATCCCCATGGCATCATGGGCCTGGGTGCCTTCTGTAACTTCAGCAC
GGAGGCCACCGAAGTTAGCAAGAAGTTCCCTGGCATAAGGCCTTATTTGGCCACATTGGCTGGC
AACTTCCGGATGCCTGTGCTTCGGGAGTACCTGATGTCTGGAGGCATCTGCCCTGTCAACAGAG
ACACCATAGACTACTTGCTTTCCAAGAATGGGAGTGGTAATGCCATTGTCATCGTGGTGGGAGG
TGCAGCTGAATCCCTGAGCTCCATGCCTGGCAAGAACGCAGTCACCCTGCGGAACCGCAAAGGC
TTTGTAAAGCTGGCCCTGCGCCATGGAGCTGATCTGGTTCCCACCTATTCCTTTGGAGAGAATG
AGGTATACAAGCAGGTGATCTTTGAGGAGGGCTCCTGGGGCCGATGGGTCCAGAAGAAGTTCCA
GAAGTATATTGGTTTCGCCCCCTGCATCTTCCATGGCCGAGGTCTCTTCTCCTCTGACACCTGG
GGGCTGGTGCCCTACTCCAAGCCCATCACCACCGTTGTGGGGGAGCCCATCACCGTCCCTAAGC
TGGAGCACCCGACCCAGAAAGACATCGACCTGTACCACACCATGTACATGGAGGCCCTGGTGAA
GCTCTTTGACAATCACAAGACCAAATTCGGCCTTCCAGAGACTGAGGTGCTGGAGGTGAACTGA
CCCAGCCCATGGGTGCCAGCTCCTGGAAGGAATGACTGCAAATCCTTTTCTACCAAGTTCTCAA
GTGCATTTTGTTCTGTAAATTTGGAAGCGTCATGGGTGTCTGTGGGTTATTTAAAAGAAATTAT
AATTTGTTAAACCATTGCAATGTTAGATCTTTTTTAAGAAGGGAAGAGTCAGTATTTTAAGCTC
ACTTCTAGTGTGTCCTGCCTAAGGTGGTGGCTGACATTTATAGGCCTTGATGGTTTCTATCCAC
CCCTTCTAGTGTTCCCCAAACAACAGACACTTGGCCCTAGTTAATTGGGGAAGGGCAGCCCTTA
GTGACTCAGCCATTTAATCCTCTTCGCTCTAGGGATTCTCAAGAGACGGAGGCCACGTTTAAAA
ACACCTCCATTCCCACCCACAACACGTGACTGCTGGTCAGGTTTTTCTTACTTAGGGGAGGATG
AGGGGGCATAGCTGGTTCCGCTTGGGGAGAGTGGTAGATAACATCTGGAATGCCCGGCTCGAGT
GTCCTCTGCTCCCCACCTACTCCTCTTCTCCAATCTGAGCCTACCCTGGCCTCCTGTACACTGT
GCTAGGGACAGGGCTGTCCCACAGGTGCCATGTTGGGTTATCTCGCTGCTGTTGGCTGGTTTTA
CTCTGGAGATTGGCATCGTGAACACAGCTCAGCGTCATTCTGGAGATGTTCTCCCAGCCACCTG
AGCTCTCCTGAGCCACACCCCAAGTCTGGTGTGAGGAGAGGCCTCTGTTCTTCACAGAGGTGCC
TGGCTTCCTGTGCAGCACACTGGGTCCAGGACAGGAGGCCACCCCCAACCAAGCCTCACCTGTG
TGCCTTTATGAGGCGTCGGGAGAAAGCCACCCTCCTGTGTATTCTGCTTTCTCCATGAGATTTT
GCCATGTCACACTTTTGTATATTCCTAGACTAATAAATGGAAACAAGAACAGCCAAAAAAAAAA
AAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006229733 ⟹ XP_006229795

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	153,454,080 - 153,466,318 (-)	NCBI
Rnor_6.0	1	164,113,459 - 164,126,055 (-)	NCBI
Rnor_5.0	1	170,316,041 - 170,346,352 (-)	NCBI

Sequence:

show sequence

ATTACCAACCTTGGGCTTTTCTCGCTTAGTCATGCAGAAAGGACAGGTATGAAGTGATAACCTT
CCTCCCCATGGCAACCAGCCTCCCGGCAGCAAGGGCTGTAGGATGTTTTCACTACACCCTTTCT
GAACTCTGAGTCCTGGCCCCCTTGGACTGAACTGAGCCTTCCTCTCTTTGCTTTGGACACTGCA
GAGGCTGGCGCCGGAGGAACCTTTTTCTGGGACCAAGGAAGGGGGCACGAGGCAAATTGTTGGA
ACGGTGTCGTATGTGCAGCCTAAATATAAGCAGGATTCTTCTCAGCTGCCTTAGGACCTACATT
ATCCTCAACAGGGTGTGTGGGCTGCAGACGCCTCCCACGACTCAGCGTCCTATGTGCGTGCCAC
TGCTAAACTGTCCTAAGAAACCACATGCCTGTTCTCCAGAAACTGTCGTCTGGTTTTAGTTCTC
CTGGGCTCAGGAGAGAGGGAGTGGCCTGCAGTGTCATCCTCATGTACACCTTCTGCACTGACTG
CTGGCTGATAGCTGCTCTCTACTTCACCTGGCTGGCATTTGACTGGAACACGCCCAAGAAAGGT
GGCAGGAGATCACAGTGGGTGCGAAACTGGGCCGTGTGGCGCTATTTTCGAGACTACTTTCCCA
TCCAGCTGGTGAAGACACACAACCTGCTGACCACCAGGAACTATATCTTTGGATACCATCCCCA
TGGCATCATGGGCCTGGGTGCCTTCTGTAACTTCAGCACGGAGGCCACCGAAGTTAGCAAGAAG
TTCCCTGGCATAAGGCCTTATTTGGCCACATTGGCTGGCAACTTCCGGATGCCTGTGCTTCGGG
AGTACCTGATGTCTGGAGGCATCTGCCCTGTCAACAGAGACACCATAGACTACTTGCTTTCCAA
GAATGGGAGTGGTAATGCCATTGTCATCGTGGTGGGAGGTGCAGCTGAATCCCTGAGCTCCATG
CCTGGCAAGAACGCAGTCACCCTGCGGAACCGCAAAGGCTTTGTAAAGCTGGCCCTGCGCCATG
GAGCTGATCTGGTTCCCACCTATTCCTTTGGAGAGAATGAGGTATACAAGCAGGTGATCTTTGA
GGAGGGCTCCTGGGGCCGATGGGTCCAGAAGAAGTTCCAGAAGTATATTGGTTTCGCCCCCTGC
ATCTTCCATGGCCGAGGTCTCTTCTCCTCTGACACCTGGGGGCTGGTGCCCTACTCCAAGCCCA
TCACCACCGTTGTGGGGGAGCCCATCACCGTCCCTAAGCTGGAGCACCCGACCCAGAAAGACAT
CGACCTGTACCACACCATGTACATGGAGGCCCTGGTGAAGCTCTTTGACAATCACAAGACCAAA
TTCGGCCTTCCAGAGACTGAGGTGCTGGAGGTGAACTGACCCAGCCCATGGGTGCCAGCTCCTG
GAAGGAATGACTGCAAATCCTTTTCTACCAAGTTCTCAAGTGCATTTTGTTCTGTAAATTTGGA
AGCGTCATGGGTGTCTGTGGGTTATTTAAAAGAAATTATAATTTGTTAAACCATTGCAATGTTA
GATCTTTTTTAAGAAGGGAAGAGTCAGTATTTTAAGCTCACTTCTAGTGTGTCCTGCCTAAGGT
GGTGGCTGACATTTATAGGCCTTGATGGTTTCTATCCACCCCTTCTAGTGTTCCCCAAACAACA
GACACTTGGCCCTAGTTAATTGGGGAAGGGCAGCCCTTAGTGACTCAGCCATTTAATCCTCTTC
GCTCTAGGGATTCTCAAGAGACGGAGGCCACGTTTAAAAACACCTCCATTCCCACCCACAACAC
GTGACTGCTGGTCAGGTTTTTCTTACTTAGGGGAGGATGAGGGGGCATAGCTGGTTCCGCTTGG
GGAGAGTGGTAGATAACATCTGGAATGCCCGGCTCGAGTGTCCTCTGCTCCCCACCTACTCCTC
TTCTCCAATCTGAGCCTACCCTGGCCTCCTGTACACTGTGCTAGGGACAGGGCTGTCCCACAGG
TGCCATGTTGGGTTATCTCGCTGCTGTTGGCTGGTTTTACTCTGGAGATTGGCATCGTGAACAC
AGCTCAGCGTCATTCTGGAGATGTTCTCCCAGCCACCTGAGCTCTCCTGAGCCACACCCCAAGT
CTGGTGTGAGGAGAGGCCTCTGTTCTTCACAGAGGTGCCTGGCTTCCTGTGCAGCACACTGGGT
CCAGGACAGGAGGCCACCCCCAACCAAGCCTCACCTGTGTGCCTTTATGAGGCGTCGGGAGAAA
GCCACCCTCCTGTGTATTCTGCTTTCTCCATGAGATTTTGCCATGTCACACTTTTGTATATTCC
TAGACTAATAAATGGAAACAAGAACAGCC

hide sequence

RefSeq Acc Id:

XM_008759689 ⟹ XP_008757911

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	153,454,078 - 153,484,057 (-)	NCBI
Rnor_6.0	1	164,113,459 - 164,143,508 (-)	NCBI

Sequence:

show sequence

CATCCCTAGGGCTTTCATCCTGAGGGACAAGGACCCACAGCAAGACGACTTTCAGGGACTATGG
CCAAGGCGTGCTGCCCTGTGCTGGACGGACGGCTAGCTAGTTCAGGCACTGGCTCCAGCATCCT
CTCGGCCCTCCAAGACATCTTCTCTGTCACCTGGCTCAACAGATCCAAGGTGGAAAAACACCTA
CAGGTCATCTCAGTCCTACAGTGGGTCCTATCCTTCCTGGTGCTAGGAGTGGCCTGCAGTGTCA
TCCTCATGTACACCTTCTGCACTGACTGCTGGCTGATAGCTGCTCTCTACTTCACCTGGCTGGC
ATTTGACTGGAACACGCCCAAGAAAGGTGGCAGGAGATCACAGTGGGTGCGAAACTGGGCCGTG
TGGCGCTATTTTCGAGACTACTTTCCCATCCAGCTGGTGAAGACACACAACCTGCTGACCACCA
GGAACTATATCTTTGGATACCATCCCCATGGCATCATGGGCCTGGGTGCCTTCTGTAACTTCAG
CACGGAGGCCACCGAAGTTAGCAAGAAGTTCCCTGGCATAAGGCCTTATTTGGCCACATTGGCT
GGCAACTTCCGGATGCCTGTGCTTCGGGAGTACCTGATGTCTGGAGGCATCTGCCCTGTCAACA
GAGACACCATAGACTACTTGCTTTCCAAGAATGGGAGTGGTAATGCCATTGTCATCGTGGTGGG
AGGTGCAGCTGAATCCCTGAGCTCCATGCCTGGCAAGAACGCAGTCACCCTGCGGAACCGCAAA
GGCTTTGTAAAGCTGGCCCTGCGCCATGGAGCTGATCTGGTTCCCACCTATTCCTTTGGAGAGA
ATGAGGTATACAAGCAGGTGATCTTTGAGGAGGGCTCCTGGGGCCGATGGGTCCAGAAGAAGTT
CCAGAAGTATATTGGTTTCGCCCCCTGCATCTTCCATGGCCGAGGTCTCTTCTCCTCTGACACC
TGGGGGCTGGTGCCCTACTCCAAGCCCATCACCACCGTTGTGGGGGAGCCCATCACCGTCCCTA
AGCTGGAGCACCCGACCCAGAAAGACATCGACCTGTACCACACCATGTACATGGAGGCCCTGGT
GAAGCTCTTTGACAATCACAAGACCAAATTCGGCCTTCCAGAGACTGAGGTGCTGGAGGTGAAC
TGACCCAGCCCATGGGTGCCAGCTCCTGGAAGGAATGACTGCAAATCCTTTTCTACCAAGTTCT
CAAGTGCATTTTGTTCTGTAAATTTGGAAGCGTCATGGGTGTCTGTGGGTTATTTAAAAGAAAT
TATAATTTGTTAAACCATTGCAATGTTAGATCTTTTTTAAGAAGGGAAGAGTCAGTATTTTAAG
CTCACTTCTAGTGTGTCCTGCCTAAGGTGGTGGCTGACATTTATAGGCCTTGATGGTTTCTATC
CACCCCTTCTAGTGTTCCCCAAACAACAGACACTTGGCCCTAGTTAATTGGGGAAGGGCAGCCC
TTAGTGACTCAGCCATTTAATCCTCTTCGCTCTAGGGATTCTCAAGAGACGGAGGCCACGTTTA
AAAACACCTCCATTCCCACCCACAACACGTGACTGCTGGTCAGGTTTTTCTTACTTAGGGGAGG
ATGAGGGGGCATAGCTGGTTCCGCTTGGGGAGAGTGGTAGATAACATCTGGAATGCCCGGCTCG
AGTGTCCTCTGCTCCCCACCTACTCCTCTTCTCCAATCTGAGCCTACCCTGGCCTCCTGTACAC
TGTGCTAGGGACAGGGCTGTCCCACAGGTGCCATGTTGGGTTATCTCGCTGCTGTTGGCTGGTT
TTACTCTGGAGATTGGCATCGTGAACACAGCTCAGCGTCATTCTGGAGATGTTCTCCCAGCCAC
CTGAGCTCTCCTGAGCCACACCCCAAGTCTGGTGTGAGGAGAGGCCTCTGTTCTTCACAGAGGT
GCCTGGCTTCCTGTGCAGCACACTGGGTCCAGGACAGGAGGCCACCCCCAACCAAGCCTCACCT
GTGTGCCTTTATGAGGCGTCGGGAGAAAGCCACCCTCCTGTGTATTCTGCTTTCTCCATGAGAT
TTTGCCATGTCACACTTTTGTATATTCCTAGACTAATAAATGGAAACAAGAACAGCC

hide sequence

RefSeq Acc Id:

XM_039101533 ⟹ XP_038957461

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	153,454,080 - 153,484,432 (-)	NCBI

RefSeq Acc Id:

XM_039101534 ⟹ XP_038957462

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	153,454,078 - 153,465,143 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001012345	(Get FASTA)	NCBI Sequence Viewer
	XP_006229795	(Get FASTA)	NCBI Sequence Viewer
	XP_008757911	(Get FASTA)	NCBI Sequence Viewer
	XP_038957461	(Get FASTA)	NCBI Sequence Viewer
	XP_038957462	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH89846	(Get FASTA)	NCBI Sequence Viewer
	CAD32178	(Get FASTA)	NCBI Sequence Viewer
	Q5FVP8	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001012345 ⟸ NM_001012345

- UniProtKB:

Q5FVP8 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MKTLIAAYSGVLRGERRAEAARSENKNKGSALSREGSGRWGTGSSILSALQDIFSVTWLNRSKV
EKHLQVISVLQWVLSFLVLGVACSVILMYTFCTDCWLIAALYFTWLAFDWNTPKKGGRRSQWVR
NWAVWRYFRDYFPIQLVKTHNLLTTRNYIFGYHPHGIMGLGAFCNFSTEATEVSKKFPGIRPYL
ATLAGNFRMPVLREYLMSGGICPVNRDTIDYLLSKNGSGNAIVIVVGGAAESLSSMPGKNAVTL
RNRKGFVKLALRHGADLVPTYSFGENEVYKQVIFEEGSWGRWVQKKFQKYIGFAPCIFHGRGLF
SSDTWGLVPYSKPITTVVGEPITVPKLEHPTQKDIDLYHTMYMEALVKLFDNHKTKFGLPETEV
LEVN

hide sequence

RefSeq Acc Id:

XP_006229795 ⟸ XM_006229733

- Peptide Label:

isoform X3

- Sequence:

show sequence

MPVLQKLSSGFSSPGLRREGVACSVILMYTFCTDCWLIAALYFTWLAFDWNTPKKGGRRSQWVR
NWAVWRYFRDYFPIQLVKTHNLLTTRNYIFGYHPHGIMGLGAFCNFSTEATEVSKKFPGIRPYL
ATLAGNFRMPVLREYLMSGGICPVNRDTIDYLLSKNGSGNAIVIVVGGAAESLSSMPGKNAVTL
RNRKGFVKLALRHGADLVPTYSFGENEVYKQVIFEEGSWGRWVQKKFQKYIGFAPCIFHGRGLF
SSDTWGLVPYSKPITTVVGEPITVPKLEHPTQKDIDLYHTMYMEALVKLFDNHKTKFGLPETEV
LEVN

hide sequence

RefSeq Acc Id:

XP_008757911 ⟸ XM_008759689

- Peptide Label:

isoform X1

- Sequence:

show sequence

MAKACCPVLDGRLASSGTGSSILSALQDIFSVTWLNRSKVEKHLQVISVLQWVLSFLVLGVACS
VILMYTFCTDCWLIAALYFTWLAFDWNTPKKGGRRSQWVRNWAVWRYFRDYFPIQLVKTHNLLT
TRNYIFGYHPHGIMGLGAFCNFSTEATEVSKKFPGIRPYLATLAGNFRMPVLREYLMSGGICPV
NRDTIDYLLSKNGSGNAIVIVVGGAAESLSSMPGKNAVTLRNRKGFVKLALRHGADLVPTYSFG
ENEVYKQVIFEEGSWGRWVQKKFQKYIGFAPCIFHGRGLFSSDTWGLVPYSKPITTVVGEPITV
PKLEHPTQKDIDLYHTMYMEALVKLFDNHKTKFGLPETEVLEVN

hide sequence

RefSeq Acc Id:

ENSRNOP00000069294 ⟸ ENSRNOT00000081669

RefSeq Acc Id:

ENSRNOP00000022557 ⟸ ENSRNOT00000022557

RefSeq Acc Id:	XP_038957462 ⟸ XM_039101534
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038957461 ⟸ XM_039101533
- Peptide Label:	isoform X2

RefSeq Acc Id:

ENSRNOP00000088100 ⟸ ENSRNOT00000114431

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5FVP8-F1-model_v2	AlphaFold	Q5FVP8	1-388	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13690224

Promoter ID:

EPDNEW_R749

Type:

multiple initiation site

Name:

Dgat2_1

Description:

diacylglycerol O-acyltransferase 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	164,143,853 - 164,143,913	EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)

ACI/EurMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

ACI/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN-Lx/CubMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/NHsdMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/NHsdMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/SsN (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BUF/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BXH2/CubMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BXH3/CubMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

DA/OlaHsd (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Envigo
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/DuCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/NCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FHH/EurMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FXLE16/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FXLE18/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

GK/FarMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB10/IpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB2/IpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB20/IpcvMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB31/IpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB4/IpcvMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LE/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEW/Crl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF10A/StmMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF11/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF1A/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF1C/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF2B/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF3/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF4/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LH/MavRrrcAek (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LL/MavRrrcAek (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LN/MavRrrcAek (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

M520/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

M520/NRrrcMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

MR/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

MWF/Hsd (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

PVG/Seac (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SHR/OlalpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SHRSP/A3NCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SR/JrHsd (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Envigo
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SS/JrHsdMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WAG/RijCrl (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WKY/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WKY/NCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WN/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620329	AgrOrtholog
BioCyc Gene	G2FUF-58405	BioCyc
BioCyc Pathway	TRIGLSYN-PWY [diacylglycerol and triacylglycerol biosynthesis]	BioCyc
Ensembl Genes	ENSRNOG00000016573	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000022557	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOP00000069294	UniProtKB/TrEMBL
	ENSRNOP00000088100	ENTREZGENE
Ensembl Transcript	ENSRNOT00000022557	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOT00000081669	UniProtKB/TrEMBL
	ENSRNOT00000114431	ENTREZGENE
IMAGE_CLONE	IMAGE:7372077	IMAGE-MGC_LOAD
InterPro	DAGAT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:252900	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:108863	IMAGE-MGC_LOAD
NCBI Gene	252900	ENTREZGENE
Pfam	DAGAT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Dgat2	PhenoGen
UniProt	A0A0G2JUZ8_RAT	UniProtKB/TrEMBL
	DGAT2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary	Q8K4Y4	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2011-08-02	Dgat2	diacylglycerol O-acyltransferase 2	Dgat2	diacylglycerol O-acyltransferase homolog 2 (mouse)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-26	Dgat2	diacylglycerol O-acyltransferase homolog 2 (mouse)	Dgat2	diacylglycerol O-acyltransferase 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-19	Dgat2	diacylglycerol O-acyltransferase 2	Dgat2	diacylglycerol O-acyltransferase homolog 2 (mouse)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	Dgat2	diacylglycerol O-acyltransferase homolog 2 (mouse)			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Dgat2	diacylglycerol O-acyltransferase homolog 2 (mouse)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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Imported Annotations - KEGG (archival)