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Gene: Sod2 (superoxide dismutase 2) Rattus norvegicus
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Symbol: Sod2
Name: superoxide dismutase 2
Description: Exhibits several functions, including manganese ion binding activity; oxygen binding activity; and superoxide dismutase activity. Involved in several processes, including cellular response to ethanol; hydrogen peroxide biosynthetic process; and removal of superoxide radicals. Localizes to mitochondrial nucleoid. Used to study esophagus adenocarcinoma; hypertension; intestinal disease; and myocardial infarction. Biomarker of several diseases, including adult respiratory distress syndrome; artery disease (multiple); bladder neck obstruction; congenital diaphragmatic hernia; and hyperhomocysteinemia. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); diabetes mellitus (multiple); lipid storage disease (multiple); optic nerve disease (multiple); and rheumatic disease (multiple). Orthologous to human SOD2 (superoxide dismutase 2); PARTICIPATES IN hypertension pathway; Huntington's disease pathway; INTERACTS WITH (+)-alpha-tocopherol; (+)-pilocarpine; (+)-schisandrin B.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: manganese superoxide dismutase; mitochondrial superoxide dismutase 2; MnSOD; Superoxide dimutase 2 mitochondrial; Superoxide dimutase 2, mitochondrial; Superoxide dismutase 2 mitochondrial; superoxide dismutase 2, mitochondrial; superoxide dismutase [Mn], mitochondrial
Orthologs:
Homo sapiens (human) : SOD2 (superoxide dismutase 2)  HGNC  Alliance
Mus musculus (house mouse) : Sod2 (superoxide dismutase 2, mitochondrial)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sod2 (superoxide dismutase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SOD2 (superoxide dismutase 2)
Canis lupus familiaris (dog) : SOD2 (superoxide dismutase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sod2 (superoxide dismutase 2)
Sus scrofa (pig) : SOD2 (superoxide dismutase 2)
Chlorocebus sabaeus (African green monkey) : SOD2 (superoxide dismutase 2)
Heterocephalus glaber (naked mole-rat) : Sod2 (superoxide dismutase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0147,914,757 - 47,921,587 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl147,914,759 - 47,921,587 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0151,827,380 - 51,834,232 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4141,862,997 - 41,870,327 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1141,865,943 - 41,873,272 (-)NCBI
Celera143,323,111 - 43,329,909 (-)NCBICelera
Cytogenetic Map1q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations