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Gene: Ect2 (epithelial cell transforming 2) Rattus norvegicus
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Symbol: Ect2
Name: epithelial cell transforming 2
RGD ID: 1308524
Description: Predicted to have GTPase activator activity; Rac guanyl-nucleotide exchange factor activity; and protein homodimerization activity. Predicted to be involved in several processes, including activation of GTPase activity; bicellular tight junction assembly; and regulation of cell cycle process. Predicted to localize to several cellular components, including bicellular tight junction; centralspindlin complex; and midbody. Orthologous to human ECT2 (epithelial cell transforming 2); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ect2 oncogene; epithelial cell transforming sequence 2 oncogene; LOC361921
Orthologs:
Homo sapiens (human) : ECT2 (epithelial cell transforming 2)  HGNC  Alliance
Mus musculus (house mouse) : Ect2 (ect2 oncogene)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ect2 (epithelial cell transforming 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ECT2 (epithelial cell transforming 2)
Canis lupus familiaris (dog) : ECT2 (epithelial cell transforming 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ect2 (epithelial cell transforming 2)
Sus scrofa (pig) : ECT2 (epithelial cell transforming 2)
Chlorocebus sabaeus (African green monkey) : ECT2 (epithelial cell transforming 2)
Heterocephalus glaber (naked mole-rat) : Ect2 (epithelial cell transforming 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02112,769,385 - 112,831,476 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2112,769,385 - 112,831,476 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02132,490,047 - 132,552,138 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42112,969,261 - 113,001,056 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12112,915,386 - 112,971,181 (-)NCBI
Celera2105,188,023 - 105,250,067 (-)NCBICelera
Cytogenetic Map2q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Ect2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308524
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.