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Gene: Ect2 (epithelial cell transforming 2) Rattus norvegicus
Symbol: Ect2
Name: epithelial cell transforming 2
Description: Predicted to have GTPase activator activity; Rho guanyl-nucleotide exchange factor activity; and protein homodimerization activity. Predicted to be involved in several processes, including activation of GTPase activity; cell morphogenesis; and regulation of cell cycle process. Predicted to localize to several cellular components, including the bicellular tight junction; centralspindlin complex; and cytosol. Orthologous to human ECT2 (epithelial cell transforming 2); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ect2 oncogene; epithelial cell transforming sequence 2 oncogene; LOC361921
Homo sapiens (human) : ECT2 (epithelial cell transforming 2)  HGNC  Alliance
Mus musculus (house mouse) : Ect2 (ect2 oncogene)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ect2 (epithelial cell transforming 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ECT2 (epithelial cell transforming 2)
Canis lupus familiaris (dog) : ECT2 (epithelial cell transforming 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ect2 (epithelial cell transforming 2)
Sus scrofa (pig) : ECT2 (epithelial cell transforming 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02112,769,385 - 112,831,476 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02132,490,047 - 132,552,138 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42112,969,261 - 113,001,056 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12112,915,386 - 112,971,181 (-)NCBI
Celera2105,188,023 - 105,250,067 (-)NCBICelera
Cytogenetic Map2q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Ect2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308524
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.