Gene: Tle1 (TLE family member 1, transcriptional corepressor) Rattus norvegicus
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Symbol: Tle1
Name: TLE family member 1, transcriptional corepressor
Description: ENCODES a protein that exhibits chromatin binding (ortholog); identical protein binding (ortholog); transcription corepressor activity (ortholog); INVOLVED IN negative regulation of anoikis (ortholog); negative regulation of I-kappaB kinase/NF-kappaB signaling (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); FOUND IN beta-catenin-TCF complex (ortholog); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC362533; MGC189561; transducin like enhancer of split 1; transducin-like enhancer of split 1; transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila); transducin-like enhancer of split 1, homolog of Drosophila E(spl); transducin-like enhancer protein 1
Orthologs:
Homo sapiens (human) : TLE1 (TLE family member 1, transcriptional corepressor)  HGNC  Alliance
Mus musculus (house mouse) : Tle1 (transducin-like enhancer of split 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tle1 (TLE family member 1, transcriptional corepressor)
Pan paniscus (bonobo/pygmy chimpanzee) : TLE1 (TLE family member 1, transcriptional corepressor)
Canis lupus familiaris (dog) : TLE1 (TLE family member 1, transcriptional corepressor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tle1 (TLE family member 1, transcriptional corepressor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0588,546,607 - 88,630,277 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0592,618,609 - 92,701,908 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4589,682,837 - 89,765,682 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1589,687,191 - 89,771,601 (-)NCBI
Celera584,643,237 - 84,725,613 (-)NCBICelera
Cytogenetic Map5q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
  
More on Tle1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309237
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2018-12-18
Status: ACTIVE



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