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Gene: Bak1 (BCL2-antagonist/killer 1) Rattus norvegicus
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Symbol: Bak1
Name: BCL2-antagonist/killer 1
Description: Exhibits several functions, including chaperone binding activity; heat shock protein binding activity; and identical protein binding activity. Involved in several processes, including animal organ development; positive regulation of release of cytochrome c from mitochondria; and release of cytochrome c from mitochondria. Localizes to cytosol; membrane; and mitochondrion. Biomarker of intermittent claudication. Human ortholog(s) of this gene implicated in ataxia telangiectasia and cervix carcinoma. Orthologous to human BAK1 (BCL2 antagonist/killer 1); PARTICIPATES IN intrinsic apoptotic pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 1,3-dinitrobenzene; 17alpha-ethynylestradiol; 1H-pyrazole.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Bak; bcl-2 homologous antagonist/killer; MGC108627
Orthologs:
Homo sapiens (human) : BAK1 (BCL2 antagonist/killer 1)  HGNC  Alliance
Mus musculus (house mouse) : Bak1 (BCL2-antagonist/killer 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bak1 (BCL2 antagonist/killer 1)
Pan paniscus (bonobo/pygmy chimpanzee) : BAK1 (BCL2 antagonist/killer 1)
Canis lupus familiaris (dog) : BAK1 (BCL2 antagonist/killer 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bak1 (BCL2 antagonist/killer 1)
Sus scrofa (pig) : BAK1 (BCL2 antagonist/killer 1)
Chlorocebus sabaeus (African green monkey) : BAK1 (BCL2 antagonist/killer 1)
Heterocephalus glaber (naked mole-rat) : Bak1 (BCL2 antagonist/killer 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0205,609,620 - 5,618,899 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,609,625 - 5,618,260 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0207,675,062 - 7,683,731 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4205,255,954 - 5,264,593 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1205,256,180 - 5,264,820 (-)NCBI
Celera206,681,267 - 6,689,805 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Bak1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621635
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.