Bak1 (BCL2-antagonist/killer 1) - Rat Genome Database

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Gene: Bak1 (BCL2-antagonist/killer 1) Rattus norvegicus
Analyze
Symbol: Bak1
Name: BCL2-antagonist/killer 1
RGD ID: 621635
Description: Exhibits several functions, including chaperone binding activity; heat shock protein binding activity; and identical protein binding activity. Involved in several processes, including animal organ development; positive regulation of release of cytochrome c from mitochondria; and release of cytochrome c from mitochondria. Localizes to cytosol; membrane; and mitochondrion. Biomarker of intermittent claudication. Human ortholog(s) of this gene implicated in ataxia telangiectasia and cervix carcinoma. Orthologous to human BAK1 (BCL2 antagonist/killer 1); PARTICIPATES IN intrinsic apoptotic pathway; Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 1,3-dinitrobenzene; 17alpha-ethynylestradiol; 1H-pyrazole.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Bak; bcl-2 homologous antagonist/killer; MGC108627
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2205,100,480 - 5,109,669 (-)NCBI
Rnor_6.0 Ensembl205,609,625 - 5,618,260 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0205,609,620 - 5,618,899 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0207,675,062 - 7,683,731 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4205,255,954 - 5,264,593 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1205,256,180 - 5,264,820 (-)NCBI
Celera206,681,267 - 6,689,805 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (ISO)
(+)-Tetrandrine  (ISO)
(-)-citrinin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(S)-(-)-perillyl alcohol  (ISO)
(S)-amphetamine  (ISO)
(S)-naringenin  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1,3-dinitrobenzene  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
1H-pyrazole  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-azacytidine  (EXP)
5-fluorouracil  (ISO)
acetamide  (EXP)
acetochlor  (ISO)
acetylsalicylic acid  (ISO)
actinomycin D  (EXP,ISO)
aflatoxin B1  (ISO)
alantolactone  (ISO)
aldehydo-D-glucose  (EXP)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
anthocyanin  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
antirheumatic drug  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (EXP,ISO)
atorvastatin calcium  (ISO)
auranofin  (ISO)
benzo[a]pyrene  (ISO)
betulinic acid  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bortezomib  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium sulfide  (ISO)
camptothecin  (ISO)
capsaicin  (ISO)
carbon nanotube  (ISO)
carvedilol  (EXP)
casticin  (ISO)
cefaloridine  (EXP)
celecoxib  (EXP,ISO)
chrysophanol  (ISO)
cisplatin  (ISO)
coenzyme Q10  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
coumarin  (ISO)
curcumin  (ISO)
cylindrospermopsin  (ISO)
D-glucose  (EXP)
DDE  (EXP)
Deguelin  (ISO)
delphinidin  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (EXP,ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (EXP,ISO)
diazinon  (EXP)
diclofenac  (ISO)
dieldrin  (EXP)
diepoxybutane  (ISO)
dioscin  (ISO)
dioxygen  (EXP,ISO)
disodium selenite  (ISO)
disulfiram  (ISO)
doxorubicin  (EXP,ISO)
entinostat  (EXP,ISO)
epichlorohydrin  (ISO)
esculetin  (ISO)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
etoposide  (ISO)
farnesol  (ISO)
fisetin  (ISO)
flavonoids  (ISO)
flufenamic acid  (ISO)
folic acid  (ISO)
fonofos  (ISO)
furan  (EXP)
furosemide  (EXP)
geraniol  (ISO)
glucose  (EXP)
gold atom  (ISO)
gold(0)  (ISO)
hydrogen peroxide  (EXP,ISO)
hyperforin  (ISO)
indometacin  (EXP,ISO)
iohexol  (ISO)
iopamidol  (ISO)
isoflurane  (EXP)
isoprenaline  (ISO)
L-ascorbic acid  (ISO)
levamisole  (ISO)
LGK974  (ISO)
linalool  (ISO)
lithocholic acid  (ISO)
losartan  (EXP)
maneb  (ISO)
mechlorethamine  (ISO)
melatonin  (EXP,ISO)
melphalan  (ISO)
menadione  (ISO)
methamphetamine  (ISO)
methotrexate  (ISO)
methoxyacetic acid  (EXP)
methyl methanesulfonate  (ISO)
minocycline  (EXP)
Mitotane  (EXP)
MK-2206  (ISO)
morphine  (ISO)
mycophenolic acid  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodiethylamine  (EXP)
navitoclax  (ISO)
nickel atom  (ISO)
nickel dichloride  (EXP)
nickel sulfate  (EXP)
niclosamide  (ISO)
nimesulide  (EXP,ISO)
Nutlin-3  (ISO)
ochratoxin A  (EXP,ISO)
okadaic acid  (ISO)
osthole  (ISO)
oxybenzone  (EXP)
p-menthan-3-ol  (ISO)
paclitaxel  (ISO)
paracetamol  (ISO)
paraquat  (EXP,ISO)
parathion  (ISO)
parthenolide  (ISO)
PD 0325901  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
perifosine  (ISO)
perillyl alcohol  (ISO)
phenobarbital  (EXP,ISO)
phorbol 13-acetate 12-myristate  (ISO)
platycodin D  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
promethazine  (ISO)
propylparaben  (ISO)
prostaglandin E2  (ISO)
pterostilbene  (ISO)
pyrrolidine dithiocarbamate  (EXP)
quercetin  (EXP,ISO)
raloxifene  (ISO)
resveratrol  (ISO)
ritonavir  (ISO)
romidepsin  (ISO)
rottlerin  (ISO)
SB 203580  (ISO)
Se-methyl-L-selenocysteine  (ISO)
Se-methylselenocysteine  (ISO)
sodium arsenite  (ISO)
sorafenib  (ISO)
streptozocin  (EXP)
succimer  (ISO)
sulindac  (ISO)
sulindac sulfide  (EXP)
sulindac sulfone  (EXP)
tamibarotene  (ISO)
TEMPO  (EXP)
terbufos  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
Thiotepa  (ISO)
trichostatin A  (EXP,ISO)
trimellitic anhydride  (ISO)
Triptolide  (EXP,ISO)
tunicamycin  (ISO)
urethane  (ISO)
ursolic acid  (ISO)
valproic acid  (ISO)
veliparib  (ISO)
vincristine  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of cysteine-type endopeptidase activity  (ISO)
activation of cysteine-type endopeptidase activity involved in apoptotic process  (ISO)
activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c  (ISO)
aging  (IEP)
animal organ regeneration  (IEP)
apoptotic process  (IMP,ISO)
apoptotic process involved in blood vessel morphogenesis  (ISO)
apoptotic signaling pathway  (ISO)
B cell apoptotic process  (ISO)
B cell homeostasis  (ISO)
B cell negative selection  (ISO)
blood vessel remodeling  (ISO)
brain development  (IEP)
cell population proliferation  (ISO)
cellular response to mechanical stimulus  (ISO)
cellular response to UV  (ISO)
endocrine pancreas development  (IEP)
establishment or maintenance of transmembrane electrochemical gradient  (ISO,ISS)
extrinsic apoptotic signaling pathway in absence of ligand  (IBA,ISO)
fibroblast apoptotic process  (ISO)
homeostasis of number of cells  (ISO)
intrinsic apoptotic signaling pathway in response to DNA damage  (IBA,ISO)
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress  (ISO)
leukocyte homeostasis  (ISO)
limb morphogenesis  (ISO)
mitochondrial fusion  (ISO)
myeloid cell homeostasis  (ISO)
negative regulation of cell population proliferation  (IMP)
negative regulation of endoplasmic reticulum calcium ion concentration  (ISO)
negative regulation of gene expression  (IMP)
negative regulation of peptidyl-serine phosphorylation  (ISO)
positive regulation of apoptotic process  (ISO)
positive regulation of calcium ion transport into cytosol  (ISO)
positive regulation of endoplasmic reticulum unfolded protein response  (ISO)
positive regulation of protein-containing complex assembly  (ISO)
positive regulation of proteolysis  (ISO)
positive regulation of release of cytochrome c from mitochondria  (IMP)
post-embryonic camera-type eye morphogenesis  (ISO)
regulation of cell cycle  (ISO)
regulation of mitochondrial membrane permeability  (ISO,ISS)
regulation of mitochondrial membrane potential  (ISO,ISS)
release of cytochrome c from mitochondria  (IMP,ISO,ISS)
response to drug  (IEP)
response to ethanol  (IEP)
response to fungus  (ISO)
response to gamma radiation  (ISO)
response to hydrogen peroxide  (IEP)
response to mycotoxin  (ISO)
response to organic cyclic compound  (IEP)
response to UV-C  (IEP)
thymocyte apoptotic process  (ISO)
vagina development  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. Adams JM and Cory S, Oncogene. 2007 Feb 26;26(9):1324-37.
2. Bowen JM, etal., Pathology. 2005 Feb;37(1):56-62.
3. Brustovetsky N, etal., J Neurochem. 2003 Jan;84(1):196-207.
4. Chi CW, etal., Eur J Pharmacol. 2008 May 31;586(1-3):35-43. Epub 2008 Feb 29.
5. Chopra M, etal., Toxicol Sci. 2009 Sep;111(1):49-63. Epub 2009 Jun 10.
6. Dharmapuri S, etal., Hum Gene Ther. 2009 Jun;20(6):589-97.
7. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
8. Gavilan MP, etal., Aging Cell. 2009 Dec;8(6):654-65. Epub 2009 Sep 11.
9. Gillick K and Crompton M, J Cell Sci. 2008 Mar 1;121(Pt 5):618-26. Epub 2008 Feb 5.
10. Gundogan F, etal., Alcohol Clin Exp Res. 2009 Dec 17.
11. Hanke J Anat Embryol (Berl). 2000 Oct;202(4):303-12.
12. Hsu SY, etal., Proc Natl Acad Sci U S A 1997 Nov 11;94(23):12401-6.
13. Isaian A, etal., J Clin Immunol. 2010 Jan;30(1):132-7. doi: 10.1007/s10875-009-9340-6. Epub 2009 Nov 7.
14. Itoh T, etal., J Neurochem 2003 Jun;85(6):1500-12.
15. Kirchhoff SR, etal., Circulation. 2002 Jun 18;105(24):2899-904.
16. Kitamura Y, etal., Brain Res. 1998 Jan 12;780(2):260-9.
17. Liberman E, etal., Digestion. 2008;77(1):48-56. Epub 2008 Mar 18.
18. Ma B, etal., PLoS One. 2013 May 2;8(5):e56580. doi: 10.1371/journal.pone.0056580. Print 2013.
19. Maheshwari A, etal., FEBS J. 2009 Feb;276(3):870-81.
20. Majewski N, etal., Mol Cell 2004 Dec 3;16(5):819-30.
21. Masson S, etal., Apoptosis. 2000 Apr;5(2):173-9.
22. MGD data from the GO Consortium
23. Mikhailov V, etal., J Biol Chem. 2003 Feb 14;278(7):5367-76. Epub 2002 Nov 25.
24. Molina EJ, etal., Biomed Pharmacother. 2009 Dec;63(10):767-72. Epub 2008 Sep 25.
25. NCBI rat LocusLink and RefSeq merged data July 26, 2002
26. Pammer J, etal., Pathol Res Pract. 1998;194(12):837-45.
27. Pipeline to import KEGG annotations from KEGG into RGD
28. Reyes NA, etal., J Clin Invest. 2010 Oct;120(10):3673-9. doi: 10.1172/JCI42986. Epub 2010 Sep 20.
29. RGD automated data pipeline
30. RGD automated import pipeline for gene-chemical interactions
31. Shimohama S, etal., Biochem Biophys Res Commun. 1998 Nov 9;252(1):92-6.
32. Soane L, etal., J Neurosci Res. 2008 May 1;86(6):1267-76.
33. Song Y, etal., Toxicology. 2008 Nov 20;253(1-3):53-61. Epub 2008 Sep 4.
34. Wang J, etal., J Biol Chem. 2004 May 7;279(19):19948-54. Epub 2004 Mar 5.
35. Wani KM, etal., Br J Cancer. 2003 May 19;88(10):1584-6.
36. Wortham NC, etal., Fertil Steril. 2006 Oct;86(4):961-71. Epub 2006 Sep 7.
Additional References at PubMed
PMID:9111042   PMID:9176392   PMID:9843949   PMID:10579309   PMID:10837489   PMID:10950869   PMID:11146504   PMID:11163212   PMID:11836241   PMID:11850803   PMID:11980919   PMID:12142566  
PMID:12477932   PMID:12847083   PMID:15613488   PMID:15680329   PMID:15776018   PMID:15901672   PMID:15955981   PMID:15967824   PMID:16055554   PMID:16199525   PMID:16439990   PMID:16446153  
PMID:16645094   PMID:16893972   PMID:17024184   PMID:17035996   PMID:17068116   PMID:17289999   PMID:17446862   PMID:18387192   PMID:18414238   PMID:18614015   PMID:19593445   PMID:19862336  
PMID:21041309   PMID:22006182   PMID:23028632   PMID:23782464   PMID:25296756   PMID:26949185   PMID:29122578   PMID:29531808  


Genomics

Comparative Map Data
Bak1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2205,100,480 - 5,109,669 (-)NCBI
Rnor_6.0 Ensembl205,609,625 - 5,618,260 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0205,609,620 - 5,618,899 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0207,675,062 - 7,683,731 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4205,255,954 - 5,264,593 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1205,256,180 - 5,264,820 (-)NCBI
Celera206,681,267 - 6,689,805 (-)NCBICelera
Cytogenetic Map20p12NCBI
BAK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl633,572,547 - 33,580,293 (-)EnsemblGRCh38hg38GRCh38
GRCh38633,572,552 - 33,580,296 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37633,540,329 - 33,548,053 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36633,648,301 - 33,656,048 (-)NCBINCBI36hg18NCBI36
Build 34633,648,306 - 33,655,959NCBI
Celera635,094,701 - 35,102,448 (-)NCBI
Cytogenetic Map6p21.31NCBI
HuRef633,281,784 - 33,289,531 (-)NCBIHuRef
CHM1_1633,542,641 - 33,550,388 (-)NCBICHM1_1
Bak1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391727,238,786 - 27,247,601 (-)NCBIGRCm39mm39
GRCm39 Ensembl1727,238,784 - 27,247,983 (-)Ensembl
GRCm381727,019,812 - 27,028,627 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1727,019,810 - 27,029,009 (-)EnsemblGRCm38mm10GRCm38
MGSCv371727,156,757 - 27,165,571 (-)NCBIGRCm37mm9NCBIm37
MGSCv361726,747,401 - 26,756,216 (-)NCBImm8
Celera1727,556,267 - 27,565,056 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
Bak1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554372,036,415 - 2,041,997 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554372,036,415 - 2,041,997 (-)NCBIChiLan1.0ChiLan1.0
BAK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1634,255,769 - 34,263,211 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl634,255,769 - 34,263,211 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0633,146,998 - 33,154,755 (-)NCBIMhudiblu_PPA_v0panPan3
BAK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1122,950,359 - 2,957,604 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl122,948,364 - 2,957,018 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha122,967,686 - 2,970,924 (-)NCBI
ROS_Cfam_1.0123,282,315 - 3,289,076 (-)NCBI
UMICH_Zoey_3.1122,950,651 - 2,953,887 (-)NCBI
UNSW_CanFamBas_1.0123,031,622 - 3,034,860 (-)NCBI
UU_Cfam_GSD_1.0123,129,752 - 3,132,990 (-)NCBI
Bak1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494638,605,488 - 38,612,704 (-)NCBI
SpeTri2.0NW_00493647625,347,608 - 25,354,772 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BAK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1729,808,849 - 29,815,345 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2734,279,191 - 34,286,287 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BAK1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11738,492,776 - 38,502,534 (+)NCBI
ChlSab1.1 Ensembl1738,492,858 - 38,501,281 (+)Ensembl
Bak1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475423,297,077 - 23,302,366 (+)NCBI

Position Markers
D20Ztm2  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0205,615,606 - 5,615,764NCBIRnor6.0
Rnor_5.0207,681,020 - 7,681,178UniSTSRnor5.0
RGSC_v3.4205,261,939 - 5,262,097UniSTSRGSC3.4
Celera206,687,154 - 6,687,312UniSTS
Cytogenetic Map20p12UniSTS
RH134024  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0205,609,634 - 5,609,813NCBIRnor6.0
Rnor_5.0207,675,075 - 7,675,254UniSTSRnor5.0
RGSC_v3.4205,255,967 - 5,256,146UniSTSRGSC3.4
Celera206,681,280 - 6,681,459UniSTS
RH 3.4 Map2055.83UniSTS
Cytogenetic Map20p12UniSTS
BE102269  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0205,618,551 - 5,618,719NCBIRnor6.0
Rnor_5.0207,683,965 - 7,684,133UniSTSRnor5.0
RGSC_v3.4205,264,884 - 5,265,052UniSTSRGSC3.4
Celera206,690,096 - 6,690,264UniSTS
RH 3.4 Map2054.8UniSTS
Cytogenetic Map20p12UniSTS
AW534505  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0205,609,976 - 5,610,126NCBIRnor6.0
Rnor_5.0207,675,417 - 7,675,567UniSTSRnor5.0
RGSC_v3.4205,256,309 - 5,256,459UniSTSRGSC3.4
Celera206,681,622 - 6,681,772UniSTS
RH 3.4 Map2056.0UniSTS
Cytogenetic Map20p12UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124652101Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125653396Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20126305996Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20126305996Rat
7387283Uae44Urinary albumin excretion QTL 440.1712urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)20127357423Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20128375393Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20128375393Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20128375393Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20128375393Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20128375393Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20133300419Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20137550487Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20137550487Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20201865447018654Rat
2306850Pia40Pristane induced arthritis QTL 400.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2020187706567419Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20299970747999707Rat
61472Aia1Adjuvant induced arthritis QTL 1180.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2031518156896013Rat
61448Ciaa1CIA Autoantibody QTL 1300.001blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)2031518156896013Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20340211127968216Rat
61474Eae1Experimental allergic encephalomyelitis QTL 13nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)2040391135875448Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20403911318872273Rat
4889857Pur27Proteinuria QTL 2712.20.001total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20403911318872273Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance in proximity to the target during voluntary locomotion in an experimental apparatus (CMO:0002674)20410895649108956Rat
1300152Bp195Blood pressure QTL 1953.46arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2048554689899946Rat
1331772Cdexp2CD45RC expression in CD8 T cells QTL 25.7CD8-positive T cell quantity (VT:0008077)blood CD45RChigh CD8 T cell count to CD45RClow CD8 T cell count ratio (CMO:0001990)20485546810800530Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20485547515050565Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:345
Count of miRNA genes:188
Interacting mature miRNAs:224
Transcripts:ENSRNOT00000000576
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 35 28 20 19 20 3 64 29 37 11
Low 8 29 21 21 8 8 10 6 4 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000000576   ⟹   ENSRNOP00000000576
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl205,609,625 - 5,618,260 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000092326   ⟹   ENSRNOP00000075913
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl205,615,771 - 5,618,254 (-)Ensembl
RefSeq Acc Id: NM_053812   ⟹   NP_446264
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2205,100,481 - 5,109,123 (-)NCBI
Rnor_6.0205,609,621 - 5,618,260 (-)NCBI
Rnor_5.0207,675,062 - 7,683,731 (-)NCBI
RGSC_v3.4205,255,954 - 5,264,593 (-)RGD
Celera206,681,267 - 6,689,805 (-)RGD
Sequence:
RefSeq Acc Id: XM_006256101   ⟹   XP_006256163
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2205,100,480 - 5,109,669 (-)NCBI
Rnor_6.0205,609,620 - 5,618,899 (-)NCBI
Rnor_5.0207,675,062 - 7,683,731 (-)NCBI
Sequence:
RefSeq Acc Id: XR_005497166
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2205,101,523 - 5,108,957 (-)NCBI
Protein Sequences
Protein RefSeqs NP_446264 (Get FASTA)   NCBI Sequence Viewer  
  XP_006256163 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF71760 (Get FASTA)   NCBI Sequence Viewer  
  AAH89784 (Get FASTA)   NCBI Sequence Viewer  
  EDL96871 (Get FASTA)   NCBI Sequence Viewer  
  EDL96872 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_446264   ⟸   NM_053812
- UniProtKB: Q9JK59 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256163   ⟸   XM_006256101
- Peptide Label: isoform X1
- UniProtKB: Q9JK59 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000075913   ⟸   ENSRNOT00000092326
RefSeq Acc Id: ENSRNOP00000000576   ⟸   ENSRNOT00000000576

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701426
Promoter ID:EPDNEW_R11948
Type:initiation region
Name:Bak1_1
Description:BCL2-antagonist/killer 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0205,618,261 - 5,618,321EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621635 AgrOrtholog
Ensembl Genes ENSRNOG00000000485 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000000576 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000075913 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000000576 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000092326 UniProtKB/TrEMBL
Gene3D-CATH 1.10.437.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7366192 IMAGE-MGC_LOAD
InterPro BAK UniProtKB/TrEMBL
  BCL2_apoptsis UniProtKB/TrEMBL
  Bcl2_BH1_motif_CS UniProtKB/TrEMBL
  Bcl2_BH2_motif_CS UniProtKB/TrEMBL
  Bcl2_BH3_motif_CS UniProtKB/TrEMBL
  Blc2-like_sf UniProtKB/TrEMBL
  Blc2_fam UniProtKB/TrEMBL
KEGG Report rno:116502 UniProtKB/TrEMBL
MGC_CLONE MGC:108627 IMAGE-MGC_LOAD
NCBI Gene 116502 ENTREZGENE
PANTHER PTHR11256 UniProtKB/TrEMBL
  PTHR11256:SF41 UniProtKB/TrEMBL
Pfam Bcl-2 UniProtKB/TrEMBL
PharmGKB BAK1 RGD
PhenoGen Bak1 PhenoGen
PRINTS BCL2FAMILY UniProtKB/TrEMBL
PROSITE BCL2_FAMILY UniProtKB/TrEMBL
  BH1 UniProtKB/TrEMBL
  BH2 UniProtKB/TrEMBL
  BH3 UniProtKB/TrEMBL
SMART BCL UniProtKB/TrEMBL
Superfamily-SCOP SSF56854 UniProtKB/TrEMBL
UniProt A0A0U1RS30_RAT UniProtKB/TrEMBL
  Q9JK59 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Bak1  BCL2-antagonist/killer 1      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Bak1  BCL2-antagonist/killer 1      Symbol and Name status set to provisional 70820 PROVISIONAL