Eif3a (eukaryotic translation initiation factor 3, subunit A) - Rat Genome Database

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Gene: Eif3a (eukaryotic translation initiation factor 3, subunit A) Rattus norvegicus
Analyze
Symbol: Eif3a
Name: eukaryotic translation initiation factor 3, subunit A
RGD ID: 1307269
Description: Enables receptor tyrosine kinase binding activity. Involved in negative regulation of ERK1 and ERK2 cascade. Located in microtubule. Orthologous to human EIF3A (eukaryotic translation initiation factor 3 subunit A); PARTICIPATES IN translation initiation pathway; RNA transport pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: eIF-3-theta; Eif3s10; eukaryotic translation initiation factor 3 subunit 10; eukaryotic translation initiation factor 3 subunit A; eukaryotic translation initiation factor 3, subunit 10 (theta); LOC292148; ZH12
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21259,902,767 - 259,932,976 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1259,902,680 - 259,932,976 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1268,109,376 - 268,139,913 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01274,815,401 - 274,845,939 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01267,469,710 - 267,500,251 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01282,139,809 - 282,170,017 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1282,139,823 - 282,170,017 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01289,478,360 - 289,508,568 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41267,369,497 - 267,399,705 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11267,580,496 - 267,610,974 (-)NCBI
Celera1255,543,560 - 255,573,769 (-)NCBICelera
Cytogenetic Map1q55NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-phenylprop-2-enal  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-vinylcyclohexene dioxide  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
benzene-1,2,4-triol  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium dichloride  (EXP)
caffeine  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chloroprene  (EXP)
chlorpyrifos  (EXP,ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
cocaine  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diazinon  (EXP)
diclofenac  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
ethanol  (ISO)
etoposide  (ISO)
flutamide  (EXP)
folic acid  (ISO)
gentamycin  (EXP)
glyphosate  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
L-ascorbic acid  (ISO)
methoxychlor  (EXP)
miconazole  (ISO)
naphthalene  (EXP)
ochratoxin A  (ISO)
oxaliplatin  (EXP)
paracetamol  (ISO)
paraquat  (EXP)
perfluorooctanoic acid  (ISO)
phenethyl isothiocyanate  (EXP)
phenobarbital  (ISO)
quercetin  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
tamibarotene  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
theophylline  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
tungsten  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. The scanning mechanism of eukaryotic translation initiation. Hinnebusch AG Annu Rev Biochem. 2014;83:779-812. doi: 10.1146/annurev-biochem-060713-035802. Epub 2014 Jan 29.
4. Activity-dependent interaction of the intracellular domain of rat trkA with intermediate filament proteins, the beta-6 proteasomal subunit, Ras-GRF1, and the p162 subunit of eIF3. MacDonald JI, etal., J Mol Neurosci. 1999 Aug-Oct;13(1-2):141-58.
5. The cholangiocyte marker, BD. 1, forms a stable complex with CLIP170 and shares an identity with eIF3a, a multifunctional subunit of the eIF3 initiation complex. Mills DR, etal., Exp Mol Pathol. 2012 Oct;93(2):250-60. doi: 10.1016/j.yexmp.2012.04.023. Epub 2012 May 18.
6. Synaptotagmin 11 interacts with components of the RNA-induced silencing complex RISC in clonal pancreatic beta-cells. Milochau A, etal., FEBS Lett. 2014 Jun 27;588(14):2217-22. doi: 10.1016/j.febslet.2014.05.031. Epub 2014 May 29.
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Proteomics profiling of nuclear proteins for kidney fibroblasts suggests hypoxia, meiosis, and cancer may meet in the nucleus. Shakib K, etal., Proteomics. 2005 Jul;5(11):2819-38.
11. Eukaryotic translation initiation factor 3, subunit a, regulates the extracellular signal-regulated kinase pathway. Xu TR, etal., Mol Cell Biol. 2012 Jan;32(1):88-95. doi: 10.1128/MCB.05770-11. Epub 2011 Oct 24.
Additional References at PubMed
PMID:9573242   PMID:12477932   PMID:17322308   PMID:17581632   PMID:18599441   PMID:19946888   PMID:21347434   PMID:22658674   PMID:22681889   PMID:22871113   PMID:23766293   PMID:24003236  
PMID:24357634   PMID:25211037   PMID:25849773   PMID:26612348   PMID:27453280   PMID:27462815   PMID:28322466   PMID:30053369   PMID:31505169   PMID:36921705  


Genomics

Comparative Map Data
Eif3a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21259,902,767 - 259,932,976 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1259,902,680 - 259,932,976 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1268,109,376 - 268,139,913 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01274,815,401 - 274,845,939 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01267,469,710 - 267,500,251 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01282,139,809 - 282,170,017 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1282,139,823 - 282,170,017 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01289,478,360 - 289,508,568 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41267,369,497 - 267,399,705 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11267,580,496 - 267,610,974 (-)NCBI
Celera1255,543,560 - 255,573,769 (-)NCBICelera
Cytogenetic Map1q55NCBI
EIF3A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810119,033,670 - 119,080,817 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10119,033,670 - 119,080,817 (-)EnsemblGRCh38hg38GRCh38
GRCh3710120,793,182 - 120,840,329 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610120,784,531 - 120,830,324 (-)NCBINCBI36Build 36hg18NCBI36
Build 3410120,784,546 - 120,830,291NCBI
Celera10114,525,146 - 114,570,792 (-)NCBICelera
Cytogenetic Map10q26.11NCBI
HuRef10114,423,579 - 114,469,868 (-)NCBIHuRef
CHM1_110121,078,880 - 121,124,758 (-)NCBICHM1_1
T2T-CHM13v2.010119,929,080 - 119,976,262 (-)NCBIT2T-CHM13v2.0
Eif3a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391960,749,554 - 60,779,131 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1960,749,555 - 60,779,096 (-)EnsemblGRCm39 Ensembl
GRCm381960,761,116 - 60,790,693 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1960,761,117 - 60,790,658 (-)EnsemblGRCm38mm10GRCm38
MGSCv371960,837,019 - 60,866,596 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361960,815,785 - 60,845,306 (-)NCBIMGSCv36mm8
Celera1962,970,389 - 62,999,944 (-)NCBICelera
Cytogenetic Map19D3NCBI
cM Map1956.52NCBI
Eif3a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543123,543,838 - 23,578,757 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543123,542,842 - 23,578,892 (-)NCBIChiLan1.0ChiLan1.0
EIF3A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan110130,901,834 - 130,948,616 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010115,608,394 - 115,654,586 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110119,030,884 - 119,077,603 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10119,033,253 - 119,072,889 (-)Ensemblpanpan1.1panPan2
EIF3A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12829,290,668 - 29,326,851 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2829,291,422 - 29,326,701 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2829,432,879 - 29,469,314 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02829,821,606 - 29,857,976 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2829,821,622 - 29,857,939 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12829,375,678 - 29,411,864 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02829,395,449 - 29,431,740 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02829,589,681 - 29,626,027 (-)NCBIUU_Cfam_GSD_1.0
Eif3a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721317,026,204 - 17,060,008 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364868,499,893 - 8,534,938 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364868,501,290 - 8,536,321 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EIF3A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14128,967,653 - 129,007,173 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114128,967,645 - 129,007,168 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214140,498,415 - 140,537,898 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EIF3A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19111,828,858 - 111,887,546 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9111,830,988 - 111,887,518 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604873,092,189 - 73,142,011 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eif3a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473727,691,762 - 27,733,638 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Eif3a
69 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:103
Count of miRNA genes:80
Interacting mature miRNAs:90
Transcripts:ENSRNOT00000066947
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1179567751260522016Rat
1358890Bp259Blood pressure QTL 2593.06arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1210702053260522016Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1216255568260522016Rat
2302040Pia35Pristane induced arthritis QTL 353.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1216255568260522016Rat
10053715Scort24Serum corticosterone level QTL 242.130.0088blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1221414816260522016Rat
724552Glom2Glomerulus QTL 23.30.0001kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)1222363780260522016Rat
1600392Bw123Body weight QTL 1230.001body mass (VT:0001259)body weight (CMO:0000012)1223201027260522016Rat
734767Niddm57Non-insulin dependent diabetes mellitus QTL 57body mass (VT:0001259)body weight (CMO:0000012)1224054293260122809Rat
631843Bw116Body weight QTL 1164.10.016abdominal adipose amount (VT:1000220)abdominal fat pad weight (CMO:0000088)1224054293260122809Rat
734769Niddm58Non-insulin dependent diabetes mellitus QTL 58body mass (VT:0001259)body weight (CMO:0000012)1224569538260122809Rat
631215Stl8Serum triglyceride level QTL 89.270.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1225126575260522016Rat
631536Lnnr2Liver neoplastic nodule remodeling QTL 22.90.0005liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)1233948574260522016Rat
631690Scl5Serum cholesterol level QTL 52.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1236125214260522016Rat
631836Stl31Serum triglyceride level QTL 314.640.00000487blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)1237147813260522016Rat
737975Bw122Body weight QTL 1229.110.005body mass (VT:0001259)body weight (CMO:0000012)1258843780260122809Rat
71112Bw115Body weight QTL 11560.0001body mass (VT:0001259)body weight (CMO:0000012)1259647732260522016Rat

Markers in Region
X84651  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21259,908,603 - 259,908,802 (+)MAPPERmRatBN7.2
Rnor_6.01282,145,646 - 282,145,844NCBIRnor6.0
Rnor_5.01289,484,197 - 289,484,395UniSTSRnor5.0
RGSC_v3.41267,375,334 - 267,375,532UniSTSRGSC3.4
Celera1255,549,397 - 255,549,595UniSTS
Cytogenetic Map1q55UniSTS
RH137966  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21259,902,256 - 259,902,427 (+)MAPPERmRatBN7.2
Rnor_6.01282,139,299 - 282,139,469NCBIRnor6.0
Rnor_5.01289,477,850 - 289,478,020UniSTSRnor5.0
RGSC_v3.41267,368,987 - 267,369,157UniSTSRGSC3.4
Celera1255,543,050 - 255,543,220UniSTS
RH 3.4 Map11710.9UniSTS
Cytogenetic Map1q55UniSTS
RH141326  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21259,903,029 - 259,903,248 (+)MAPPERmRatBN7.2
Rnor_6.01282,140,072 - 282,140,290NCBIRnor6.0
Rnor_5.01289,478,623 - 289,478,841UniSTSRnor5.0
RGSC_v3.41267,369,760 - 267,369,978UniSTSRGSC3.4
Celera1255,543,823 - 255,544,041UniSTS
RH 3.4 Map11711.5UniSTS
Cytogenetic Map1q55UniSTS
UniSTS:237988  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21259,903,266 - 259,903,398 (+)MAPPERmRatBN7.2
Rnor_6.01282,140,309 - 282,140,440NCBIRnor6.0
Rnor_5.01289,478,860 - 289,478,991UniSTSRnor5.0
RGSC_v3.41267,369,997 - 267,370,128UniSTSRGSC3.4
Celera1255,544,060 - 255,544,191UniSTS
Cytogenetic Map1q55UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000066947   ⟹   ENSRNOP00000063484
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1259,902,684 - 259,932,954 (-)Ensembl
Rnor_6.0 Ensembl1282,139,823 - 282,170,017 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000095164   ⟹   ENSRNOP00000090156
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1259,902,680 - 259,926,007 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000114025   ⟹   ENSRNOP00000090615
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1259,903,375 - 259,932,976 (-)Ensembl
RefSeq Acc Id: NM_001047087   ⟹   NP_001040552
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21259,902,767 - 259,932,976 (-)NCBI
Rnor_6.01282,139,809 - 282,170,017 (-)NCBI
Rnor_5.01289,478,360 - 289,508,568 (-)NCBI
RGSC_v3.41267,369,497 - 267,399,705 (-)RGD
Celera1255,543,560 - 255,573,769 (-)RGD
Sequence:
RefSeq Acc Id: NP_001040552   ⟸   NM_001047087
- UniProtKB: Q1JU68 (UniProtKB/Swiss-Prot),   A6JIA5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000063484   ⟸   ENSRNOT00000066947
RefSeq Acc Id: ENSRNOP00000090615   ⟸   ENSRNOT00000114025
RefSeq Acc Id: ENSRNOP00000090156   ⟸   ENSRNOT00000095164
Protein Domains
PCI

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q1JU68-F1-model_v2 AlphaFold Q1JU68 1-1354 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691021
Promoter ID:EPDNEW_R1546
Type:multiple initiation site
Name:Eif3a_1
Description:eukaryotic translation initiation factor 3, subunit A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01282,169,974 - 282,170,034EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307269 AgrOrtholog
BioCyc Gene G2FUF-55225 BioCyc
Ensembl Genes ENSRNOG00000010117 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055029926 UniProtKB/Swiss-Prot
  ENSRNOG00060000037 UniProtKB/Swiss-Prot
  ENSRNOG00065005807 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000066947 ENTREZGENE
  ENSRNOT00000066947.4 UniProtKB/Swiss-Prot
  ENSRNOT00000095164.1 UniProtKB/TrEMBL
  ENSRNOT00000114025.1 UniProtKB/TrEMBL
  ENSRNOT00055051898 UniProtKB/Swiss-Prot
  ENSRNOT00060000041 UniProtKB/Swiss-Prot
  ENSRNOT00065008716 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.40.860 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UVR domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro EIF3A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PCI_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:292148 UniProtKB/Swiss-Prot
NCBI Gene 292148 ENTREZGENE
PANTHER EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR14005 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PCI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Eif3a PhenoGen
PROSITE PCI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000010117 RatGTEx
  ENSRNOG00055029926 RatGTEx
  ENSRNOG00060000037 RatGTEx
  ENSRNOG00065005807 RatGTEx
SMART PINT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6A8S5_RAT UniProtKB/TrEMBL
  A0A8I6GJ08_RAT UniProtKB/TrEMBL
  A6JIA5 ENTREZGENE, UniProtKB/TrEMBL
  EIF3A_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-04-20 Eif3a  eukaryotic translation initiation factor 3, subunit A  Eif3s10  eukaryotic translation initiation factor 3, subunit 10 (theta)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Eif3s10  eukaryotic translation initiation factor 3, subunit 10 (theta)  Eif3s10_predicted  eukaryotic translation initiation factor 3, subunit 10 (theta) (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Eif3s10_predicted  eukaryotic translation initiation factor 3, subunit 10 (theta) (predicted)      Symbol and Name status set to approved 70820 APPROVED