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Gene: Gpsm2 (G-protein signaling modulator 2) Rattus norvegicus
Symbol: Gpsm2
Name: G-protein signaling modulator 2
RGD ID: 1560967
Description: Predicted to have several functions, including G-protein alpha-subunit binding activity; dynein complex binding activity; and protein C-terminus binding activity. Predicted to be involved in several processes, including maintenance of centrosome location; microtubule cytoskeleton organization involved in mitosis; and regulation of spindle organization. Predicted to colocalize with cell cortex. Human ortholog(s) of this gene implicated in sensorineural hearing loss. Orthologous to human GPSM2 (G protein signaling modulator 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; 6-propyl-2-thiouracil.
Type: protein-coding
Also known as: G-protein signaling modulator 2 (AGS3-like, C. elegans); G-protein signalling modulator 2 (AGS3-like, C. elegans); G-protein-signaling modulator 2; LOC362021; RGD1560967; similar to Pins
Homo sapiens (human) : GPSM2 (G protein signaling modulator 2)  HGNC  Alliance
Mus musculus (house mouse) : Gpsm2 (G-protein signalling modulator 2 (AGS3-like, C. elegans))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gpsm2 (G protein signaling modulator 2)
Pan paniscus (bonobo/pygmy chimpanzee) : GPSM2 (G protein signaling modulator 2)
Canis lupus familiaris (dog) : GPSM2 (G protein signaling modulator 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gpsm2 (G protein signaling modulator 2)
Sus scrofa (pig) : GPSM2 (G protein signaling modulator 2)
Chlorocebus sabaeus (African green monkey) : GPSM2 (G protein signaling modulator 2)
Heterocephalus glaber (naked mole-rat) : Gpsm2 (G protein signaling modulator 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02211,480,120 - 211,528,096 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2211,480,400 - 211,527,919 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02230,953,071 - 230,992,673 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42204,278,765 - 204,319,522 (-)NCBIRGSC3.4rn4RGSC3.4
Celera2188,970,456 - 189,014,462 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Gpsm2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1560967
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.