 Gene-Chemical Interaction AnnotationsTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-alpha-tocopherol | multiple interactions | ISO | RGD:731412 | 6480464 | [Tretinoin co-treated with alpha-Tocopherol] results in increased expression of CRABP2 mRNA, [Tretinoin co-treated with alpha-Tocopherol] results in increased expression of CRABP2 protein | CTD | PMID:15225641 | (S)-nicotine | decreases expression | ISO | RGD:731412 | 6480464 | Nicotine results in decreased expression of CRABP2 mRNA | CTD | PMID:16949557 | 17alpha-ethynylestradiol | increases expression | ISO | RGD:62362 | 6480464 | Ethinyl Estradiol results in increased expression of CRABP2 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | multiple interactions | ISO | RGD:62362 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CRABP2 mRNA | CTD | PMID:17942748 | 17beta-estradiol | multiple interactions | ISO | RGD:731412 | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of CRABP2 mRNA, [Progesterone co-treated with Estradiol] results in decreased expression of CRABP2 mRNA | CTD | PMID:17404688, PMID:30165855 | 17beta-estradiol | decreases expression | ISO | RGD:731412 | 6480464 | Estradiol results in decreased expression of CRABP2 mRNA | CTD | PMID:23019147 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:62362 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CRABP2 mRNA, Tetrachlorodibenzodioxin inhibits the reaction [Tretinoin results in increased expression of CRABP2 mRNA] | CTD | PMID:17942748, PMID:7864861 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:62362 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CRABP2 mRNA | CTD | PMID:17035482 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | RGD:62362 | 6480464 | tetrabromobisphenol A results in decreased expression of CRABP2 mRNA | CTD | PMID:25172293 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | RGD:731412 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of CRABP2 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | decreases expression | ISO | RGD:731412 | 6480464 | bis(4-hydroxyphenyl)sulfone results in decreased expression of CRABP2 mRNA | CTD | PMID:25912373 | 4-tert-Octylphenol | increases expression | EXP | | 6480464 | 4-tert-octylphenol results in increased expression of CRABP2 mRNA | CTD | PMID:17011747 | 5-fluorouracil | affects expression | ISO | RGD:62362 | 6480464 | Fluorouracil affects the expression of CRABP2 protein | CTD | PMID:21296659 | 7,12-dimethyltetraphene | increases expression | ISO | RGD:731412 | 6480464 | 9 more ... | CTD | PMID:21527772 | 8'-apo-beta,psi-caroten-8'-al | decreases expression | ISO | RGD:731412 | 6480464 | apocarotenal results in decreased expression of CRABP2 mRNA | CTD | PMID:17034753 | acetic acid | increases expression | ISO | RGD:62362 | 6480464 | Acetic Acid results in increased expression of CRABP2 protein | CTD | PMID:21296659 | actinomycin D | increases expression | ISO | RGD:731412 | 6480464 | Dactinomycin results in increased expression of CRABP2 mRNA | CTD | PMID:21527772 | adapalene | increases expression | ISO | RGD:731412 | 6480464 | Adapalene results in increased expression of CRABP2 mRNA | CTD | PMID:8396608, PMID:9990415 | aflatoxin B1 | decreases expression | EXP | | 6480464 | Aflatoxin B1 results in decreased expression of CRABP2 mRNA | CTD | PMID:23630614 | aflatoxin B1 | increases expression | ISO | RGD:731412 | 6480464 | Aflatoxin B1 results in increased expression of CRABP2 mRNA | CTD | PMID:21527772, PMID:22100608 | alachlor | increases expression | EXP | | 6480464 | alachlor results in increased expression of CRABP2 mRNA | CTD | PMID:12419858 | all-trans-4-oxoretinoic acid | increases expression | ISO | RGD:731412 | 6480464 | 4-oxoretinoic acid results in increased expression of CRABP2 mRNA | CTD | PMID:17034753 | all-trans-4-oxoretinol | increases expression | ISO | RGD:731412 | 6480464 | 4-oxoretinol results in increased expression of CRABP2 mRNA | CTD | PMID:17034753 | all-trans-retinoic acid | affects expression | EXP | | 6480464 | Tretinoin affects the expression of CRABP2 mRNA | CTD | PMID:22262565 | all-trans-retinoic acid | increases expression | ISO | RGD:731412 | 6480464 | Tretinoin results in increased expression of CRABP2 mRNA | CTD | PMID:11214822 more ... | all-trans-retinoic acid | affects binding | ISO | RGD:731412 | 6480464 | Tretinoin binds to CRABP2 protein | CTD | PMID:15958702 | all-trans-retinoic acid | multiple interactions | ISO | RGD:731412 | 6480464 | [Tretinoin co-treated with alpha-Tocopherol] results in increased expression of CRABP2 mRNA more ... | CTD | PMID:15225641 more ... | all-trans-retinoic acid | increases response to substance | ISO | RGD:731412 | 6480464 | CRABP2 protein results in increased susceptibility to Tretinoin | CTD | PMID:16166294 | all-trans-retinoic acid | affects expression | ISO | RGD:62362 | 6480464 | Tretinoin affects the expression of CRABP2 protein | CTD | PMID:15789344 | all-trans-retinoic acid | affects binding | ISO | RGD:62362 | 6480464 | Tretinoin binds to CRABP2 protein | CTD | PMID:17387344 | all-trans-retinoic acid | increases expression | EXP | | 6480464 | Tretinoin analog results in increased expression of CRABP2 mRNA, Tretinoin results in increased expression of CRABP2 mRNA | CTD | PMID:16946489, PMID:20488242 | all-trans-retinoic acid | increases expression | ISO | RGD:62362 | 6480464 | Tretinoin results in increased expression of CRABP2, Tretinoin results in increased expression of CRABP2 mRNA | CTD | PMID:16038797 more ... | all-trans-retinoic acid | multiple interactions | ISO | RGD:62362 | 6480464 | Tetrachlorodibenzodioxin inhibits the reaction [Tretinoin results in increased expression of CRABP2 mRNA] | CTD | PMID:7864861 | all-trans-retinol | multiple interactions | ISO | RGD:731412 | 6480464 | CRABP2 protein promotes the reaction [Vitamin A results in increased expression of TOB1 mRNA] | CTD | PMID:17234770 | all-trans-retinol | increases expression | ISO | RGD:731412 | 6480464 | Vitamin A results in increased expression of CRABP2 mRNA | CTD | PMID:16793012, PMID:17034753 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of CRABP2 mRNA | CTD | PMID:16483693 | antirheumatic drug | increases expression | ISO | RGD:731412 | 6480464 | Antirheumatic Agents results in increased expression of CRABP2 mRNA | CTD | PMID:24449571 | Aroclor 1254 | increases expression | ISO | RGD:62362 | 6480464 | Chlorodiphenyl (54% Chlorine) results in increased expression of CRABP2 mRNA | CTD | PMID:23650126 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of CRABP2 mRNA | CTD | PMID:21839799 | benzo[a]pyrene | decreases expression | ISO | RGD:62362 | 6480464 | Benzo(a)pyrene results in decreased expression of CRABP2 mRNA | CTD | PMID:25908611 | Benzo[k]fluoranthene | decreases expression | ISO | RGD:62362 | 6480464 | benzo(k)fluoranthene results in decreased expression of CRABP2 mRNA | CTD | PMID:26377693 | bis(2-chloroethyl) sulfide | increases expression | ISO | RGD:62362 | 6480464 | Mustard Gas results in increased expression of CRABP2 mRNA | CTD | PMID:15674843 | bis(2-chloroethyl) sulfide | increases expression | ISO | RGD:731412 | 6480464 | Mustard Gas results in increased expression of CRABP2 mRNA | CTD | PMID:25102026 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CRABP2 mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | ISO | RGD:62362 | 6480464 | bisphenol A results in increased expression of CRABP2 mRNA | CTD | PMID:26063408 | bisphenol F | multiple interactions | ISO | RGD:731412 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of CRABP2 mRNA | CTD | PMID:28628672 | bromochloroacetic acid | increases expression | ISO | RGD:62362 | 6480464 | bromochloroacetic acid results in increased expression of CRABP2 protein | CTD | PMID:21296659 | butanal | increases expression | ISO | RGD:731412 | 6480464 | butyraldehyde results in increased expression of CRABP2 mRNA | CTD | PMID:26079696 | cisplatin | affects expression | ISO | RGD:731412 | 6480464 | Cisplatin affects the expression of CRABP2 mRNA | CTD | PMID:23300844 | copper atom | multiple interactions | ISO | RGD:731412 | 6480464 | [Disulfiram binds to Copper] which results in decreased expression of CRABP2 mRNA, [NSC 689534 binds to Copper] which results in decreased expression of CRABP2 mRNA | CTD | PMID:20971185, PMID:24690739 | copper(0) | multiple interactions | ISO | RGD:731412 | 6480464 | [Disulfiram binds to Copper] which results in decreased expression of CRABP2 mRNA, [NSC 689534 binds to Copper] which results in decreased expression of CRABP2 mRNA | CTD | PMID:20971185, PMID:24690739 | copper(2+) | multiple interactions | ISO | RGD:731412 | 6480464 | [Disulfiram binds to Copper] which results in decreased expression of CRABP2 mRNA, [NSC 689534 binds to Copper] which results in decreased expression of CRABP2 mRNA | CTD | PMID:20971185, PMID:24690739 | cyclophosphamide | increases expression | ISO | RGD:731412 | 6480464 | Cyclophosphamide results in increased expression of CRABP2 mRNA | CTD | PMID:21527772 | cyclosporin A | decreases methylation | ISO | RGD:731412 | 6480464 | Cyclosporine results in decreased methylation of CRABP2 promoter | CTD | PMID:27989131 | delta-tocopherol | multiple interactions | ISO | RGD:731412 | 6480464 | [Tretinoin co-treated with delta-tocopherol] results in increased expression of CRABP2 mRNA | CTD | PMID:15225641 | dexamethasone | decreases expression | ISO | RGD:62362 | 6480464 | Dexamethasone results in decreased expression of CRABP2 mRNA | CTD | PMID:20228061, PMID:22733784 | dexamethasone | multiple interactions | ISO | RGD:731412 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of CRABP2 mRNA | CTD | PMID:28628672 | dibenz[a,h]anthracene | decreases expression | ISO | RGD:731412 | 6480464 | 1 more ... | CTD | PMID:16269432 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of CRABP2 mRNA, Dibutyl Phthalate results in decreased expression of CRABP2 protein | CTD | PMID:17379624 more ... | diethylstilbestrol | increases expression | EXP | | 6480464 | Diethylstilbestrol results in increased expression of CRABP2 mRNA | CTD | PMID:17011747 | disulfiram | multiple interactions | ISO | RGD:731412 | 6480464 | [Disulfiram binds to Copper] which results in decreased expression of CRABP2 mRNA | CTD | PMID:24690739 | dorsomorphin | multiple interactions | ISO | RGD:731412 | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | elemental selenium | increases expression | EXP | | 6480464 | Selenium deficiency results in increased expression of CRABP2 mRNA | CTD | PMID:11444866 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of CRABP2 mRNA | CTD | PMID:29391264 | etoposide | increases expression | ISO | RGD:731412 | 6480464 | Etoposide results in increased expression of CRABP2 mRNA | CTD | PMID:21527772 | flavonoids | increases expression | EXP | | 6480464 | Flavonoids results in increased expression of CRABP2 mRNA | CTD | PMID:18035473 | flusilazole | increases expression | EXP | | 6480464 | flusilazole results in increased expression of CRABP2 mRNA | CTD | PMID:22664269 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of CRABP2 mRNA | CTD | PMID:27387713 | gamma-tocopherol | multiple interactions | ISO | RGD:731412 | 6480464 | [Tretinoin co-treated with gamma-Tocopherol] results in increased expression of CRABP2 mRNA | CTD | PMID:15225641 | indometacin | multiple interactions | ISO | RGD:731412 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of CRABP2 mRNA | CTD | PMID:28628672 | isotretinoin | increases expression | ISO | RGD:731412 | 6480464 | Isotretinoin results in increased expression of CRABP2 mRNA | CTD | PMID:17486130 | isotretinoin | multiple interactions | ISO | RGD:731412 | 6480464 | R116010 promotes the reaction [Isotretinoin results in increased expression of CRABP2 mRNA] | CTD | PMID:17486130 | methyl methanesulfonate | increases expression | ISO | RGD:731412 | 6480464 | Methyl Methanesulfonate results in increased expression of CRABP2 mRNA | CTD | PMID:21527772 | methylseleninic acid | increases expression | ISO | RGD:731412 | 6480464 | methylselenic acid results in increased expression of CRABP2 mRNA | CTD | PMID:18548127 | N-nitrosodiethylamine | increases expression | ISO | RGD:731412 | 6480464 | Diethylnitrosamine results in increased expression of CRABP2 mRNA | CTD | PMID:21527772 | nickel sulfate | decreases expression | ISO | RGD:731412 | 6480464 | nickel sulfate results in decreased expression of CRABP2 mRNA | CTD | PMID:22714537 | nicotine | decreases expression | ISO | RGD:731412 | 6480464 | Nicotine results in decreased expression of CRABP2 mRNA | CTD | PMID:16949557 | panobinostat | multiple interactions | ISO | RGD:731412 | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CRABP2 mRNA | CTD | PMID:27188386 | panobinostat | increases expression | ISO | RGD:731412 | 6480464 | panobinostat results in increased expression of CRABP2 mRNA | CTD | PMID:26272509 | pentane-2,3-dione | increases expression | EXP | | 6480464 | 2, 3-pentanedione results in increased expression of CRABP2 mRNA | CTD | PMID:25710175 | potassium dichromate | increases expression | ISO | RGD:731412 | 6480464 | Potassium Dichromate results in increased expression of CRABP2 protein | CTD | PMID:23718831 | progesterone | decreases expression | ISO | RGD:62362 | 6480464 | Progesterone results in decreased expression of CRABP2 mRNA | CTD | PMID:22238285 | progesterone | multiple interactions | ISO | RGD:731412 | 6480464 | [Progesterone co-treated with Estradiol] results in decreased expression of CRABP2 mRNA | CTD | PMID:17404688 | propanal | increases expression | ISO | RGD:731412 | 6480464 | propionaldehyde results in increased expression of CRABP2 mRNA | CTD | PMID:26079696 | resveratrol | increases expression | ISO | RGD:731412 | 6480464 | resveratrol results in increased expression of CRABP2 mRNA | CTD | PMID:12002526, PMID:15280659 | resveratrol | increases expression | ISO | RGD:62362 | 6480464 | resveratrol results in increased expression of CRABP2 protein | CTD | PMID:25505154 | SB 431542 | multiple interactions | ISO | RGD:731412 | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | selenium atom | increases expression | EXP | | 6480464 | Selenium deficiency results in increased expression of CRABP2 mRNA | CTD | PMID:11444866 | sodium arsenite | affects methylation | ISO | RGD:731412 | 6480464 | sodium arsenite affects the methylation of CRABP2 gene | CTD | PMID:28589171 | sodium arsenite | decreases expression | ISO | RGD:731412 | 6480464 | sodium arsenite results in decreased expression of CRABP2 mRNA | CTD | PMID:12016162 | tetrathiomolybdate(2-) | decreases expression | ISO | RGD:731412 | 6480464 | tetrathiomolybdate analog results in decreased expression of CRABP2 mRNA | CTD | PMID:19323979 | thapsigargin | decreases expression | ISO | RGD:731412 | 6480464 | Thapsigargin results in decreased expression of CRABP2 mRNA | CTD | PMID:22378314 | tributylstannane | increases expression | EXP | | 6480464 | tributyltin results in increased expression of CRABP2 mRNA | CTD | PMID:21683754 | trichostatin A | increases expression | ISO | RGD:731412 | 6480464 | trichostatin A results in increased expression of CRABP2 mRNA | CTD | PMID:24935251, PMID:26272509 | trichostatin A | multiple interactions | ISO | RGD:731412 | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CRABP2 mRNA | CTD | PMID:27188386 | triclosan | decreases expression | ISO | RGD:731412 | 6480464 | Triclosan results in decreased expression of CRABP2 mRNA | CTD | PMID:30510588 | tunicamycin | decreases expression | ISO | RGD:731412 | 6480464 | Tunicamycin results in decreased expression of CRABP2 mRNA | CTD | PMID:22378314 | valproic acid | increases expression | ISO | RGD:62362 | 6480464 | Valproic Acid results in increased expression of CRABP2 mRNA | CTD | PMID:21427059, PMID:24896083 | valproic acid | multiple interactions | ISO | RGD:731412 | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CRABP2 mRNA | CTD | PMID:27188386 | valproic acid | increases expression | ISO | RGD:731412 | 6480464 | Valproic Acid results in increased expression of CRABP2 mRNA | CTD | PMID:23179753 more ... | valproic acid | increases methylation | ISO | RGD:731412 | 6480464 | Valproic Acid results in increased methylation of CRABP2 gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | RGD:731412 | 6480464 | Valproic Acid affects the expression of CRABP2 mRNA | CTD | PMID:25979313 | vitamin E | multiple interactions | ISO | RGD:731412 | 6480464 | [Tretinoin co-treated with alpha-Tocopherol] results in increased expression of CRABP2 mRNA, [Tretinoin co-treated with alpha-Tocopherol] results in increased expression of CRABP2 protein | CTD | PMID:15225641 | vorinostat | increases expression | ISO | RGD:731412 | 6480464 | vorinostat results in increased expression of CRABP2 mRNA | CTD | PMID:26272509 | vorinostat | multiple interactions | ISO | RGD:731412 | 6480464 | [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CRABP2 mRNA | CTD | PMID:27188386 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology AnnotationsBiological Process
Cellular Component
Molecular Function
Molecular Pathway Annotations
