Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References FTP Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner
Aging & Age-Related Disease Cancer Cardiovascular Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Genetic Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Entpd2 (ectonucleoside triphosphate diphosphohydrolase 2) Rattus norvegicus
Analyze
Symbol: Entpd2
Name: ectonucleoside triphosphate diphosphohydrolase 2
Description: Exhibits ATPase activity; adenosine-diphosphatase activity; and identical protein binding activity. Involved in several processes, including cellular response to cytokine stimulus; cellular response to lipopolysaccharide; and response to auditory stimulus. Localizes to the cell body; cell projection membrane; and cell surface. Biomarker of hypertension. Human ortholog(s) of this gene implicated in malignant glioma. Orthologous to human ENTPD2 (ectonucleoside triphosphate diphosphohydrolase 2); PARTICIPATES IN purine metabolic pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,4-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CD39 antigen-like 1; Cd39l1; ecto-ATP diphosphohydrolase 2; ecto-ATPase 2; ecto-ATPDase 2; NTPDase 2; NTPDase2; nucleoside triphosphate diphosphohydrolase 2; testicular ecto-ATPase
Orthologs:
Homo sapiens (human) : ENTPD2 (ectonucleoside triphosphate diphosphohydrolase 2)  HGNC  Alliance
Mus musculus (house mouse) : Entpd2 (ectonucleoside triphosphate diphosphohydrolase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Entpd2 (ectonucleoside triphosphate diphosphohydrolase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ENTPD2 (ectonucleoside triphosphate diphosphohydrolase 2)
Canis lupus familiaris (dog) : ENTPD2 (ectonucleoside triphosphate diphosphohydrolase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Entpd2 (ectonucleoside triphosphate diphosphohydrolase 2)
Sus scrofa (pig) : ENTPD2 (ectonucleoside triphosphate diphosphohydrolase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.032,617,795 - 2,623,818 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.032,599,211 - 2,605,231 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.433,564,380 - 3,569,801 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.133,564,379 - 3,569,800 (+)NCBI
Celera33,038,775 - 3,044,196 (+)NCBICelera
Cytogenetic Map3p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
  
More on Entpd2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69266
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



Contact Us |  About Us |  License CC BY 4.0 |  Legal Disclaimer |  © Medical College of Wisconsin
NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.