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Gene: Ftl1 (ferritin light chain 1) Rattus norvegicus
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Symbol: Ftl1
Name: ferritin light chain 1
Description: Predicted to have ferroxidase activity; identical protein binding activity; and iron ion binding activity. Involved in response to lead ion. Localizes to the cytoplasm. Human ortholog(s) of this gene implicated in basal ganglia disease; hyperferritinemia-cataract syndrome; neurodegeneration with brain iron accumulation 3; and neurodegenerative disease. Orthologous to human FTL (ferritin light chain); PARTICIPATES IN iron storage pathway; porphyrin and chlorophyll metabolic pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ferritin L subunit 1; ferritin light chain; ferritin, light polypeptide; Ftl
Orthologs:
Homo sapiens (human) : FTL (ferritin light chain)  HGNC  Alliance
Mus musculus (house mouse) : Ftl1 (ferritin light polypeptide 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ftl (ferritin light chain)
Pan paniscus (bonobo/pygmy chimpanzee) : FTL (ferritin light chain)
Canis lupus familiaris (dog) : FTL (ferritin light chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ftl (ferritin light chain)
Sus scrofa (pig) : FTL (ferritin light chain)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01101,448,190 - 101,450,034 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01102,527,136 - 102,528,980 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,929,248 - 95,931,092 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1196,007,368 - 96,009,121 (-)NCBI
Celera190,192,302 - 90,194,146 (-)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ftl1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61813
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.