Gene: Nectin2 (nectin cell adhesion molecule 2) Rattus norvegicus
Analyze
Symbol: Nectin2
Name: nectin cell adhesion molecule 2
Description: ENCODES a protein that exhibits cell adhesion molecule binding (ortholog); identical protein binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN acrosome assembly (ortholog); adhesion of symbiont to host (ortholog); cell part morphogenesis (ortholog); PARTICIPATES IN E-cadherin signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Experimental Liver Cirrhosis (ortholog); multiple sclerosis (ortholog); FOUND IN apical junction complex (ortholog); cell surface (ortholog); cell-cell contact zone (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,3-dinitrobenzene; 1-naphthyl isothiocyanate
AGR Description: Predicted to have cell adhesion molecule binding activity and protein homodimerization activity; predicted to be involved in several processes, including gamete generation, positive regulation of immune response, and viral life cycle; predicted to localize to several cellular components, including the cell surface, cell-cell contact zone, and integral component of membrane; orthologous to human NECTIN2 (nectin cell adhesion molecule 2).
Merged Description: Predicted to have cell adhesion molecule binding activity and protein homodimerization activity; predicted to be involved in several processes, including gamete generation, positive regulation of immune response, and viral life cycle; predicted to localize to several cellular components, including the cell surface, cell-cell contact zone, and integral component of membrane; orthologous to human NECTIN2 (nectin cell adhesion molecule 2); PARTICIPATES IN E-cadherin signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,3-dinitrobenzene; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC308417; MGC94554; nectin-2; poliovirus receptor related 2; poliovirus receptor-related 2; poliovirus receptor-related 2 (herpesvirus entry mediator B); poliovirus receptor-related protein 2; Pvrl2
Orthologs:
Homo sapiens (human) : NECTIN2 (nectin cell adhesion molecule 2)  HGNC  Alliance
Mus musculus (house mouse) : Nectin2 (nectin cell adhesion molecule 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nectin2 (nectin cell adhesion molecule 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NECTIN2 (nectin cell adhesion molecule 2)
Canis lupus familiaris (dog) : NECTIN2 (nectin cell adhesion molecule 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nectin2 (nectin cell adhesion molecule 2)
Sus scrofa (pig) : NECTIN2 (nectin cell adhesion molecule 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0180,631,449 - 80,666,617 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0181,896,927 - 81,932,099 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4179,021,831 - 79,059,686 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1179,099,942 - 79,137,797 (-)NCBI
Celera173,831,315 - 73,865,827 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Nectin2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309505
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.