PVR (PVR cell adhesion molecule) - Rat Genome Database

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Gene: PVR (PVR cell adhesion molecule) Homo sapiens
Analyze
Symbol: PVR
Name: PVR cell adhesion molecule
RGD ID: 736513
HGNC Page HGNC:9705
Description: Enables cell adhesion molecule binding activity and receptor ligand activity. Involved in natural killer cell mediated cytotoxicity and regulation of leukocyte mediated cytotoxicity. Located in cell surface and membrane. Is active in plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: CD155; FLJ25946; HVED; Necl-5; NECL5; nectin-like 5; nectin-like protein 5; poliovirus receptor; PVS; TAGE4; tumor-associated antigen 1
RGD Orthologs
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381944,643,910 - 44,666,162 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1944,643,798 - 44,666,162 (+)EnsemblGRCh38hg38GRCh38
GRCh371945,147,210 - 45,169,430 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361949,839,066 - 49,858,690 (+)NCBINCBI36Build 36hg18NCBI36
Build 341949,839,065 - 49,858,689NCBI
Celera1941,951,144 - 41,973,471 (+)NCBICelera
Cytogenetic Map19q13.31NCBI
HuRef1941,579,341 - 41,601,754 (+)NCBIHuRef
CHM1_11945,149,748 - 45,172,111 (+)NCBICHM1_1
T2T-CHM13v2.01947,468,632 - 47,490,944 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-diaminotoluene  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP)
bisphenol A  (EXP,ISO)
Bisphenol B  (EXP)
bromobenzene  (ISO)
cadmium dichloride  (EXP,ISO)
carbofuran  (ISO)
carbon nanotube  (ISO)
cefaloridine  (ISO)
chloroform  (ISO)
cisplatin  (EXP)
Cuprizon  (ISO)
cyclosporin A  (EXP,ISO)
cyproconazole  (ISO)
D-glucose  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (EXP)
dioxygen  (ISO)
doxorubicin  (EXP,ISO)
endosulfan  (ISO)
fluoranthene  (ISO)
folic acid  (EXP,ISO)
formaldehyde  (ISO)
furan  (ISO)
gentamycin  (ISO)
glucose  (ISO)
glycidol  (ISO)
gold atom  (EXP)
gold(0)  (EXP)
graphite  (ISO)
indole-3-methanol  (ISO)
isoprenaline  (ISO)
ivermectin  (EXP)
lead(0)  (EXP)
leflunomide  (EXP)
lidocaine  (ISO)
lipopolysaccharide  (EXP,ISO)
manganese atom  (EXP)
manganese(0)  (EXP)
manganese(II) chloride  (EXP)
mercury dichloride  (ISO)
methamphetamine  (ISO)
methapyrilene  (ISO)
methimazole  (ISO)
methoxychlor  (ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
nickel atom  (EXP)
nickel dichloride  (ISO)
orphenadrine  (ISO)
oxaliplatin  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
paraquat  (ISO)
PCB138  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (ISO)
phenylephrine  (ISO)
pirinixic acid  (ISO)
propiconazole  (ISO)
ranitidine  (ISO)
rotenone  (EXP,ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (EXP)
silicon dioxide  (ISO)
Soman  (ISO)
sulfadimethoxine  (ISO)
tert-butyl hydroperoxide  (EXP)
tetrachloromethane  (ISO)
tetracycline  (ISO)
thioacetamide  (ISO)
topotecan  (ISO)
torcetrapib  (EXP)
triadimefon  (ISO)
trichloroethene  (ISO)
triptonide  (ISO)
valproic acid  (EXP)
vancomycin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. RGD HPO Phenotype Annotation Pipeline RGD automated import pipeline for human HPO-to-gene-to-disease annotations
Additional References at PubMed
PMID:1331527   PMID:1701111   PMID:1851992   PMID:2170108   PMID:2538245   PMID:7914388   PMID:10618374   PMID:10737800   PMID:10841575   PMID:11437656   PMID:11573956   PMID:11751937  
PMID:11983699   PMID:12011057   PMID:12195344   PMID:12477932   PMID:12663789   PMID:12759359   PMID:12913096   PMID:12943679   PMID:14652024   PMID:14702039   PMID:15034010   PMID:15039383  
PMID:15057824   PMID:15076773   PMID:15136589   PMID:15194502   PMID:15194795   PMID:15279713   PMID:15471548   PMID:15489334   PMID:15536144   PMID:15607800   PMID:15640804   PMID:16216929  
PMID:16304049   PMID:16335952   PMID:16344560   PMID:16831868   PMID:17446174   PMID:17507470   PMID:17534374   PMID:17717529   PMID:17893876   PMID:18029348   PMID:19011098   PMID:19011627  
PMID:19056733   PMID:19319949   PMID:19322201   PMID:19801517   PMID:19815499   PMID:20331633   PMID:20634891   PMID:21330602   PMID:21383766   PMID:21423176   PMID:21833088   PMID:21873635  
PMID:21982860   PMID:21988832   PMID:21998457   PMID:22169283   PMID:22301152   PMID:22363471   PMID:22692919   PMID:22929570   PMID:22939629   PMID:23154388   PMID:23276719   PMID:23333754  
PMID:23376485   PMID:23980210   PMID:24045107   PMID:24598754   PMID:24755620   PMID:24817116   PMID:24828608   PMID:25113908   PMID:25209846   PMID:25320021   PMID:25416956   PMID:25609078  
PMID:25631086   PMID:25862891   PMID:25972481   PMID:26186194   PMID:26656785   PMID:26842126   PMID:27049654   PMID:27296670   PMID:27733551   PMID:27834324   PMID:28084312   PMID:28395975  
PMID:28514442   PMID:28515320   PMID:28611215   PMID:28730595   PMID:28816021   PMID:28870470   PMID:28883004   PMID:29117863   PMID:29180619   PMID:29381645   PMID:29431243   PMID:29568061  
PMID:29878245   PMID:30024968   PMID:30039180   PMID:30528596   PMID:30591568   PMID:30880756   PMID:31035013   PMID:31036057   PMID:31073040   PMID:31253644   PMID:31280863   PMID:31372841  
PMID:31377744   PMID:31383549   PMID:31387897   PMID:31485637   PMID:31515488   PMID:31830330   PMID:31883911   PMID:31954274   PMID:31995728   PMID:32040157   PMID:32296183   PMID:32321756  
PMID:32345648   PMID:32353859   PMID:32409323   PMID:32411795   PMID:32446718   PMID:32554931   PMID:32727790   PMID:32804915   PMID:32807901   PMID:32902876   PMID:32917981   PMID:33053330  
PMID:33060197   PMID:33185939   PMID:33399495   PMID:33504618   PMID:33545068   PMID:33576304   PMID:33616718   PMID:33845483   PMID:33855917   PMID:33879814   PMID:33961781   PMID:34030043  
PMID:34115802   PMID:34353426   PMID:34504191   PMID:34514998   PMID:34608548   PMID:34709727   PMID:35262683   PMID:35324958   PMID:35337019   PMID:35384245   PMID:35384345   PMID:35696571  
PMID:35729552   PMID:35858240   PMID:35870689   PMID:35947095   PMID:36215168   PMID:36630913   PMID:37075705   PMID:37383234   PMID:37491355   PMID:37499664   PMID:37522595   PMID:37565582  
PMID:37629138   PMID:37660884   PMID:37995180   PMID:38176170   PMID:38216949   PMID:38289706   PMID:38291470   PMID:38592213   PMID:38604326   PMID:38945485  


Genomics

Comparative Map Data
PVR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381944,643,910 - 44,666,162 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1944,643,798 - 44,666,162 (+)EnsemblGRCh38hg38GRCh38
GRCh371945,147,210 - 45,169,430 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361949,839,066 - 49,858,690 (+)NCBINCBI36Build 36hg18NCBI36
Build 341949,839,065 - 49,858,689NCBI
Celera1941,951,144 - 41,973,471 (+)NCBICelera
Cytogenetic Map19q13.31NCBI
HuRef1941,579,341 - 41,601,754 (+)NCBIHuRef
CHM1_11945,149,748 - 45,172,111 (+)NCBICHM1_1
T2T-CHM13v2.01947,468,632 - 47,490,944 (+)NCBIT2T-CHM13v2.0
Pvr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39719,637,503 - 19,655,068 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl719,637,503 - 19,655,085 (-)EnsemblGRCm39 Ensembl
GRCm38719,903,578 - 19,921,143 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl719,903,578 - 19,921,160 (-)EnsemblGRCm38mm10GRCm38
MGSCv37720,488,927 - 20,506,492 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36719,062,100 - 19,079,613 (-)NCBIMGSCv36mm8
Celera717,310,717 - 17,327,912 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.95NCBI
Pvr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8188,689,235 - 88,704,641 (-)NCBIGRCr8
mRatBN7.2179,561,294 - 79,576,700 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl179,546,879 - 79,576,715 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx184,955,696 - 84,971,120 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0193,505,836 - 93,521,203 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0186,710,813 - 86,726,237 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0180,820,306 - 80,835,712 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl180,820,050 - 80,835,701 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0182,085,555 - 82,100,961 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4179,213,654 - 79,229,063 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1179,291,499 - 79,307,163 (-)NCBI
Celera174,018,461 - 74,033,867 (-)NCBICelera
RH 3.4 Map1819.8RGD
Cytogenetic Map1q21NCBI
PVR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22050,803,497 - 50,823,257 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11952,675,478 - 52,695,282 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01941,592,042 - 41,614,397 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11950,196,980 - 50,216,832 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1950,196,980 - 50,217,006 (+)Ensemblpanpan1.1panPan2
PVR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11110,692,906 - 110,713,209 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1110,697,911 - 110,754,296 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1110,175,812 - 110,196,115 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01111,257,096 - 111,277,399 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1111,261,295 - 111,277,390 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11110,898,742 - 110,919,041 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01110,534,429 - 110,554,736 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01111,404,145 - 111,424,445 (-)NCBIUU_Cfam_GSD_1.0
Pvr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934917,009,613 - 17,022,236 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367061,357,041 - 1,370,442 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367061,356,690 - 1,369,547 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PVR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1651,161,320 - 51,178,464 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2647,020,048 - 47,038,024 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103234825
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1638,127,864 - 38,141,612 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023667612773 - 12,781 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in PVR
51 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh37/hg19 19q13.2-13.32(chr19:43013365-47241534)x1 copy number loss See cases [RCV000240182] Chr19:43013365..47241534 [GRCh37]
Chr19:19q13.2-13.32		 pathogenic
chr19:44501518-45322744 complex variant complex Breast ductal adenocarcinoma [RCV000207162] Chr19:44501518..45322744 [GRCh37]
Chr19:19q13.31-13.32		 uncertain significance
GRCh37/hg19 19q13.31-13.32(chr19:44300416-45639540)x1 copy number loss See cases [RCV000512107] Chr19:44300416..45639540 [GRCh37]
Chr19:19q13.31-13.32		 uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888) copy number gain See cases [RCV000512296] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)x3 copy number gain See cases [RCV000511289] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic|uncertain significance
NM_006505.5(PVR):c.1168G>A (p.Ala390Thr) single nucleotide variant not specified [RCV004298751] Chr19:44661309 [GRCh38]
Chr19:45164576 [GRCh37]
Chr19:19q13.31		 uncertain significance
NM_006505.5(PVR):c.673C>G (p.His225Asp) single nucleotide variant not specified [RCV004304774] Chr19:44650054 [GRCh38]
Chr19:45153326 [GRCh37]
Chr19:19q13.31		 uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:68029-59110290)x3 copy number gain not provided [RCV000752439] Chr19:68029..59110290 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-59097160)x3 copy number gain not provided [RCV000752444] Chr19:260912..59097160 [GRCh37]
Chr19:19p13.3-q13.43		 pathogenic
GRCh37/hg19 19q11-13.33(chr19:28271106-49213832)x3 copy number gain not provided [RCV000845733] Chr19:28271106..49213832 [GRCh37]
Chr19:19q11-13.33		 pathogenic
GRCh37/hg19 19q13.31-13.42(chr19:44738088-53621561)x3 copy number gain not provided [RCV001007050] Chr19:44738088..53621561 [GRCh37]
Chr19:19q13.31-13.42		 pathogenic
NM_006505.5(PVR):c.717C>T (p.Thr239=) single nucleotide variant PVR-related disorder [RCV003933033]|not provided [RCV000914976] Chr19:44650098 [GRCh38]
Chr19:45153370 [GRCh37]
Chr19:19q13.31		 benign|likely benign
GRCh37/hg19 19q13.31-13.32(chr19:45074342-46133841) copy number gain not specified [RCV002052686] Chr19:45074342..46133841 [GRCh37]
Chr19:19q13.31-13.32		 uncertain significance
NC_000019.9:g.(?_44011002)_(45213778_?)dup duplication Ethylmalonic encephalopathy [RCV003116731] Chr19:44011002..45213778 [GRCh37]
Chr19:19q13.31-13.32		 uncertain significance
NM_006505.5(PVR):c.949G>A (p.Ala317Thr) single nucleotide variant not specified [RCV004234630] Chr19:44657868 [GRCh38]
Chr19:45161136 [GRCh37]
Chr19:19q13.31		 uncertain significance
NM_006505.5(PVR):c.206A>T (p.His69Leu) single nucleotide variant not specified [RCV004148088] Chr19:44647349 [GRCh38]
Chr19:45150621 [GRCh37]
Chr19:19q13.31		 uncertain significance
NM_006505.5(PVR):c.950C>T (p.Ala317Val) single nucleotide variant not specified [RCV004234631] Chr19:44657869 [GRCh38]
Chr19:45161137 [GRCh37]
Chr19:19q13.31		 uncertain significance
NM_006505.5(PVR):c.229G>T (p.Val77Phe) single nucleotide variant not specified [RCV004159732] Chr19:44647372 [GRCh38]
Chr19:45150644 [GRCh37]
Chr19:19q13.31		 uncertain significance
NM_006505.5(PVR):c.929T>C (p.Leu310Ser) single nucleotide variant not specified [RCV004115549] Chr19:44657848 [GRCh38]
Chr19:45161116 [GRCh37]
Chr19:19q13.31		 uncertain significance
NM_006505.5(PVR):c.206A>G (p.His69Arg) single nucleotide variant not specified [RCV004205890] Chr19:44647349 [GRCh38]
Chr19:45150621 [GRCh37]
Chr19:19q13.31		 uncertain significance
NM_006505.5(PVR):c.489G>A (p.Met163Ile) single nucleotide variant not specified [RCV004163246] Chr19:44649870 [GRCh38]
Chr19:45153142 [GRCh37]
Chr19:19q13.31		 uncertain significance
NM_006505.5(PVR):c.566C>T (p.Thr189Met) single nucleotide variant not specified [RCV004242889] Chr19:44649947 [GRCh38]
Chr19:45153219 [GRCh37]
Chr19:19q13.31		 uncertain significance
NM_006505.5(PVR):c.539A>G (p.His180Arg) single nucleotide variant not specified [RCV004202413] Chr19:44649920 [GRCh38]
Chr19:45153192 [GRCh37]
Chr19:19q13.31		 likely benign
NM_006505.5(PVR):c.1115G>A (p.Arg372His) single nucleotide variant not specified [RCV004212052] Chr19:44658865 [GRCh38]
Chr19:45162133 [GRCh37]
Chr19:19q13.31		 uncertain significance
NM_006505.5(PVR):c.899G>A (p.Arg300His) single nucleotide variant not specified [RCV004218389] Chr19:44657818 [GRCh38]
Chr19:45161086 [GRCh37]
Chr19:19q13.31		 likely benign
NM_006505.5(PVR):c.1005T>A (p.Ser335Arg) single nucleotide variant not specified [RCV004204854] Chr19:44658755 [GRCh38]
Chr19:45162023 [GRCh37]
Chr19:19q13.31		 uncertain significance
NM_006505.5(PVR):c.683T>C (p.Phe228Ser) single nucleotide variant not specified [RCV004150335] Chr19:44650064 [GRCh38]
Chr19:45153336 [GRCh37]
Chr19:19q13.31		 uncertain significance
NM_006505.5(PVR):c.553G>A (p.Gly185Arg) single nucleotide variant not specified [RCV004142488] Chr19:44649934 [GRCh38]
Chr19:45153206 [GRCh37]
Chr19:19q13.31		 uncertain significance
NM_006505.5(PVR):c.740C>T (p.Ser247Phe) single nucleotide variant not specified [RCV004133255] Chr19:44653915 [GRCh38]
Chr19:45157184 [GRCh37]
Chr19:19q13.31		 uncertain significance
NM_006505.5(PVR):c.479C>G (p.Pro160Arg) single nucleotide variant not specified [RCV004358868] Chr19:44649860 [GRCh38]
Chr19:45153132 [GRCh37]
Chr19:19q13.31		 uncertain significance
NM_006505.5(PVR):c.1162G>A (p.Ala388Thr) single nucleotide variant not specified [RCV004438237] Chr19:44661303 [GRCh38]
Chr19:45164570 [GRCh37]
Chr19:19q13.31		 uncertain significance
NM_006505.5(PVR):c.1204A>C (p.Ser402Arg) single nucleotide variant not specified [RCV004438239] Chr19:44661761 [GRCh38]
Chr19:45165028 [GRCh37]
Chr19:19q13.31		 uncertain significance
NM_006505.5(PVR):c.56T>C (p.Leu19Pro) single nucleotide variant not specified [RCV004438245] Chr19:44644152 [GRCh38]
Chr19:45147452 [GRCh37]
Chr19:19q13.31		 uncertain significance
NM_006505.5(PVR):c.646G>A (p.Gly216Ser) single nucleotide variant not specified [RCV004438246] Chr19:44650027 [GRCh38]
Chr19:45153299 [GRCh37]
Chr19:19q13.31		 uncertain significance
NM_006505.5(PVR):c.1240G>A (p.Glu414Lys) single nucleotide variant not specified [RCV004438241] Chr19:44661797 [GRCh38]
Chr19:45165064 [GRCh37]
Chr19:19q13.31		 uncertain significance
NM_006505.5(PVR):c.1025G>A (p.Arg342His) single nucleotide variant not specified [RCV004438236] Chr19:44658775 [GRCh38]
Chr19:45162043 [GRCh37]
Chr19:19q13.31		 uncertain significance
NM_006505.5(PVR):c.1205G>C (p.Ser402Thr) single nucleotide variant not specified [RCV004438240] Chr19:44661762 [GRCh38]
Chr19:45165029 [GRCh37]
Chr19:19q13.31		 uncertain significance
NM_006505.5(PVR):c.883G>A (p.Ala295Thr) single nucleotide variant PVR-related disorder [RCV003907331] Chr19:44657802 [GRCh38]
Chr19:45161070 [GRCh37]
Chr19:19q13.31		 benign
NM_006505.5(PVR):c.676G>A (p.Glu226Lys) single nucleotide variant PVR-related disorder [RCV003903943] Chr19:44650057 [GRCh38]
Chr19:45153329 [GRCh37]
Chr19:19q13.31		 benign
NM_006505.5(PVR):c.179A>G (p.His60Arg) single nucleotide variant not specified [RCV004438242] Chr19:44647322 [GRCh38]
Chr19:45150594 [GRCh37]
Chr19:19q13.31		 uncertain significance
NM_006505.5(PVR):c.952C>T (p.Leu318=) single nucleotide variant PVR-related disorder [RCV003972282] Chr19:44657871 [GRCh38]
Chr19:45161139 [GRCh37]
Chr19:19q13.31		 benign
NM_006505.5(PVR):c.303G>A (p.Ala101=) single nucleotide variant PVR-related disorder [RCV003934630] Chr19:44647446 [GRCh38]
Chr19:45150718 [GRCh37]
Chr19:19q13.31		 likely benign
NM_006505.5(PVR):c.348G>A (p.Glu116=) single nucleotide variant PVR-related disorder [RCV003919768] Chr19:44647491 [GRCh38]
Chr19:45150763 [GRCh37]
Chr19:19q13.31		 benign
NM_006505.5(PVR):c.516C>T (p.Arg172=) single nucleotide variant PVR-related disorder [RCV003951966] Chr19:44649897 [GRCh38]
Chr19:45153169 [GRCh37]
Chr19:19q13.31		 likely benign
NM_006505.5(PVR):c.-1C>T single nucleotide variant PVR-related disorder [RCV003932194] Chr19:44644096 [GRCh38]
Chr19:45147396 [GRCh37]
Chr19:19q13.31		 benign
NM_006505.5(PVR):c.1180G>C (p.Gly394Arg) single nucleotide variant not specified [RCV004438238] Chr19:44661321 [GRCh38]
Chr19:45164588 [GRCh37]
Chr19:19q13.31		 uncertain significance
NM_006505.5(PVR):c.952C>G (p.Leu318Val) single nucleotide variant not specified [RCV004438248] Chr19:44657871 [GRCh38]
Chr19:45161139 [GRCh37]
Chr19:19q13.31		 uncertain significance
NM_006505.5(PVR):c.933C>T (p.Ile311=) single nucleotide variant PVR-related disorder [RCV003946917] Chr19:44657852 [GRCh38]
Chr19:45161120 [GRCh37]
Chr19:19q13.31		 likely benign
NM_006505.5(PVR):c.199G>A (p.Ala67Thr) single nucleotide variant PVR-related disorder [RCV003964374] Chr19:44647342 [GRCh38]
Chr19:45150614 [GRCh37]
Chr19:19q13.31		 benign
NM_006505.5(PVR):c.947A>G (p.Asn316Ser) single nucleotide variant PVR-related disorder [RCV003947007] Chr19:44657866 [GRCh38]
Chr19:45161134 [GRCh37]
Chr19:19q13.31		 likely benign
NM_006505.5(PVR):c.343G>C (p.Val115Leu) single nucleotide variant not specified [RCV004438244] Chr19:44647486 [GRCh38]
Chr19:45150758 [GRCh37]
Chr19:19q13.31		 uncertain significance
NM_006505.5(PVR):c.88G>A (p.Val30Ile) single nucleotide variant not specified [RCV004438247] Chr19:44647231 [GRCh38]
Chr19:45150503 [GRCh37]
Chr19:19q13.31		 uncertain significance
NM_006505.5(PVR):c.376G>A (p.Val126Ile) single nucleotide variant not specified [RCV004669297] Chr19:44647519 [GRCh38]
Chr19:45150791 [GRCh37]
Chr19:19q13.31		 uncertain significance
NM_006505.5(PVR):c.788C>T (p.Thr263Ile) single nucleotide variant not specified [RCV004662761] Chr19:44653963 [GRCh38]
Chr19:45157232 [GRCh37]
Chr19:19q13.31		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3979
Count of miRNA genes:902
Interacting mature miRNAs:1077
Transcripts:ENST00000187830, ENST00000344956, ENST00000403059, ENST00000406449, ENST00000425690, ENST00000587785
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1559110SCL22_HSerum cholesterol level QTL 22 (human)3.590.000241Lipid levelLDL cholesterol193190759457907594Human
1331657COPD9_HChronic obstructive pulmonary disease QTL 9 (human)1.94Chronic airflow obstructionpost-bronchodilator FEV1193102176057021760Human

Markers in Region
SHGC-31865  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371945,166,709 - 45,166,834UniSTSGRCh37
Build 361949,858,549 - 49,858,674RGDNCBI36
Celera1941,970,752 - 41,970,877RGD
Cytogenetic Map19q13.2UniSTS
HuRef1941,599,035 - 41,599,160UniSTS
Stanford-G3 RH Map192297.0UniSTS
GeneMap99-GB4 RH Map19250.72UniSTS
Whitehead-RH Map19332.4UniSTS
NCBI RH Map19490.6UniSTS
GeneMap99-G3 RH Map192308.0UniSTS
STS-H99988  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371945,166,582 - 45,166,827UniSTSGRCh37
Build 361949,858,422 - 49,858,667RGDNCBI36
Celera1941,970,625 - 41,970,870RGD
Cytogenetic Map19q13.2UniSTS
HuRef1941,598,908 - 41,599,153UniSTS
GeneMap99-GB4 RH Map19250.51UniSTS
NCBI RH Map19484.8UniSTS
SHGC-144216  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371945,165,793 - 45,166,094UniSTSGRCh37
Build 361949,857,633 - 49,857,934RGDNCBI36
Celera1941,969,836 - 41,970,137RGD
Cytogenetic Map19q13.2UniSTS
HuRef1941,598,119 - 41,598,420UniSTS
TNG Radiation Hybrid Map1916805.0UniSTS
RH35929  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371945,169,044 - 45,169,225UniSTSGRCh37
Build 361949,860,884 - 49,861,065RGDNCBI36
Celera1941,973,086 - 41,973,267RGD
Cytogenetic Map19q13.2UniSTS
HuRef1941,601,369 - 41,601,550UniSTS
GeneMap99-GB4 RH Map19250.82UniSTS
NCBI RH Map19484.8UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2437 2788 2245 4961 1725 2350 5 622 1883 465 2268 7235 6404 51 3723 851 1740 1615 175 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_008781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001135768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001135769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001135770 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_006505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC068948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC243964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH009286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI374885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK025949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK094177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK098812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK290946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK300349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC015542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE838104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA416069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA849917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DC400059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HH958003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M24406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M24407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X64116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X64118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X64119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X64120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X64121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X64122 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X64123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X94226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000187830   ⟹   ENSP00000187830
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1944,643,914 - 44,663,583 (+)Ensembl
Ensembl Acc Id: ENST00000344956   ⟹   ENSP00000340870
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1944,643,798 - 44,663,583 (+)Ensembl
Ensembl Acc Id: ENST00000403059   ⟹   ENSP00000385344
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1944,643,910 - 44,663,583 (+)Ensembl
Ensembl Acc Id: ENST00000406449   ⟹   ENSP00000383907
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1944,644,097 - 44,659,094 (+)Ensembl
Ensembl Acc Id: ENST00000425690   ⟹   ENSP00000402060
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1944,643,910 - 44,666,162 (+)Ensembl
Ensembl Acc Id: ENST00000587785   ⟹   ENSP00000466447
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1944,650,041 - 44,661,880 (+)Ensembl
Ensembl Acc Id: ENST00000706603   ⟹   ENSP00000516465
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1944,643,820 - 44,663,562 (+)Ensembl
Ensembl Acc Id: ENST00000706604   ⟹   ENSP00000516466
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1944,643,833 - 44,663,562 (+)Ensembl
Ensembl Acc Id: ENST00000706605
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1944,643,858 - 44,663,562 (+)Ensembl
Ensembl Acc Id: ENST00000706606   ⟹   ENSP00000516467
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1944,643,872 - 44,655,567 (+)Ensembl
Ensembl Acc Id: ENST00000706607   ⟹   ENSP00000516468
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1944,643,872 - 44,663,568 (+)Ensembl
Ensembl Acc Id: ENST00000706608
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1944,657,559 - 44,665,409 (+)Ensembl
RefSeq Acc Id: NM_001135768   ⟹   NP_001129240
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381944,643,910 - 44,666,162 (+)NCBI
GRCh371945,147,098 - 45,169,429 (+)ENTREZGENE
HuRef1941,579,341 - 41,601,754 (+)ENTREZGENE
CHM1_11945,149,748 - 45,172,111 (+)NCBI
T2T-CHM13v2.01947,468,632 - 47,490,944 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001135769   ⟹   NP_001129241
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381944,643,910 - 44,666,162 (+)NCBI
GRCh371945,147,098 - 45,169,429 (+)ENTREZGENE
HuRef1941,579,341 - 41,601,754 (+)ENTREZGENE
CHM1_11945,149,748 - 45,172,111 (+)NCBI
T2T-CHM13v2.01947,468,632 - 47,490,944 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001135770   ⟹   NP_001129242
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381944,643,910 - 44,659,094 (+)NCBI
GRCh371945,147,098 - 45,169,429 (+)ENTREZGENE
HuRef1941,579,341 - 41,601,754 (+)ENTREZGENE
CHM1_11945,149,748 - 45,165,044 (+)NCBI
T2T-CHM13v2.01947,468,632 - 47,483,874 (+)NCBI
Sequence:
RefSeq Acc Id: NM_006505   ⟹   NP_006496
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381944,643,910 - 44,666,162 (+)NCBI
GRCh371945,147,098 - 45,169,429 (+)ENTREZGENE
Build 361949,839,066 - 49,858,690 (+)NCBI Archive
HuRef1941,579,341 - 41,601,754 (+)ENTREZGENE
CHM1_11945,149,748 - 45,172,111 (+)NCBI
T2T-CHM13v2.01947,468,632 - 47,490,944 (+)NCBI
Sequence:
RefSeq Acc Id: NP_006496   ⟸   NM_006505
- Peptide Label: isoform alpha precursor
- UniProtKB: Q96BJ1 (UniProtKB/Swiss-Prot),   Q15268 (UniProtKB/Swiss-Prot),   Q15267 (UniProtKB/Swiss-Prot),   P15152 (UniProtKB/Swiss-Prot),   B4DTS9 (UniProtKB/Swiss-Prot),   P15151 (UniProtKB/Swiss-Prot),   A0A0C4DG49 (UniProtKB/TrEMBL),   A8K4I1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001129240   ⟸   NM_001135768
- Peptide Label: isoform beta precursor
- UniProtKB: Q96BJ1 (UniProtKB/Swiss-Prot),   Q15268 (UniProtKB/Swiss-Prot),   Q15267 (UniProtKB/Swiss-Prot),   P15152 (UniProtKB/Swiss-Prot),   B4DTS9 (UniProtKB/Swiss-Prot),   P15151 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001129241   ⟸   NM_001135769
- Peptide Label: isoform gamma precursor
- UniProtKB: Q96BJ1 (UniProtKB/Swiss-Prot),   Q15268 (UniProtKB/Swiss-Prot),   Q15267 (UniProtKB/Swiss-Prot),   P15152 (UniProtKB/Swiss-Prot),   B4DTS9 (UniProtKB/Swiss-Prot),   P15151 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001129242   ⟸   NM_001135770
- Peptide Label: isoform delta precursor
- UniProtKB: Q96BJ1 (UniProtKB/Swiss-Prot),   Q15268 (UniProtKB/Swiss-Prot),   Q15267 (UniProtKB/Swiss-Prot),   P15152 (UniProtKB/Swiss-Prot),   B4DTS9 (UniProtKB/Swiss-Prot),   P15151 (UniProtKB/Swiss-Prot),   A0A0A0MSA9 (UniProtKB/TrEMBL),   A8K4I1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000402060   ⟸   ENST00000425690
Ensembl Acc Id: ENSP00000466447   ⟸   ENST00000587785
Ensembl Acc Id: ENSP00000385344   ⟸   ENST00000403059
Ensembl Acc Id: ENSP00000383907   ⟸   ENST00000406449
Ensembl Acc Id: ENSP00000340870   ⟸   ENST00000344956
Ensembl Acc Id: ENSP00000187830   ⟸   ENST00000187830
Ensembl Acc Id: ENSP00000516467   ⟸   ENST00000706606
Ensembl Acc Id: ENSP00000516468   ⟸   ENST00000706607
Ensembl Acc Id: ENSP00000516466   ⟸   ENST00000706604
Ensembl Acc Id: ENSP00000516465   ⟸   ENST00000706603
Protein Domains
Ig-like   Ig-like C2-type   Ig-like V-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P15151-F1-model_v2 AlphaFold P15151 1-417 view protein structure

Promoters
RGD ID:7240329
Promoter ID:EPDNEW_H25910
Type:initiation region
Name:PVR_1
Description:poliovirus receptor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H25911  EPDNEW_H25912  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381944,643,910 - 44,643,970EPDNEW
RGD ID:7240331
Promoter ID:EPDNEW_H25911
Type:initiation region
Name:PVR_3
Description:poliovirus receptor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H25910  EPDNEW_H25912  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381944,644,013 - 44,644,073EPDNEW
RGD ID:7240333
Promoter ID:EPDNEW_H25912
Type:initiation region
Name:PVR_2
Description:poliovirus receptor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H25910  EPDNEW_H25911  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381944,663,144 - 44,663,204EPDNEW
RGD ID:6795967
Promoter ID:HG_KWN:30225
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000406449,   NM_001135768,   NM_001135769,   NM_006505,   OTTHUMT00000323018
Position:
Human AssemblyChrPosition (strand)Source
Build 361949,838,756 - 49,839,256 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:9705 AgrOrtholog
COSMIC PVR COSMIC
Ensembl Genes ENSG00000073008 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000187830.2 UniProtKB/TrEMBL
  ENST00000344956 ENTREZGENE
  ENST00000344956.8 UniProtKB/Swiss-Prot
  ENST00000403059 ENTREZGENE
  ENST00000403059.8 UniProtKB/Swiss-Prot
  ENST00000406449 ENTREZGENE
  ENST00000406449.8 UniProtKB/TrEMBL
  ENST00000425690 ENTREZGENE
  ENST00000425690.8 UniProtKB/TrEMBL
  ENST00000587785.1 UniProtKB/TrEMBL
  ENST00000706603.1 UniProtKB/TrEMBL
  ENST00000706604.1 UniProtKB/TrEMBL
  ENST00000706606.1 UniProtKB/TrEMBL
  ENST00000706607.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000073008 GTEx
HGNC ID HGNC:9705 ENTREZGENE
Human Proteome Map PVR Human Proteome Map
InterPro CD80_C2-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nectin/PVR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:5817 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 5817 ENTREZGENE
OMIM 173850 OMIM
PANTHER NECTIN-2 UniProtKB/Swiss-Prot
  NECTIN-2 UniProtKB/Swiss-Prot
  NECTIN-2 UniProtKB/TrEMBL
  NECTIN-2 UniProtKB/TrEMBL
Pfam C2-set_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA34050 PharmGKB
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IGv UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0A0MSA9 ENTREZGENE, UniProtKB/TrEMBL
  A0A0C4DG49 ENTREZGENE, UniProtKB/TrEMBL
  A0A9L9PX39_HUMAN UniProtKB/TrEMBL
  A0A9L9PXB8_HUMAN UniProtKB/TrEMBL
  A0A9L9PXN8_HUMAN UniProtKB/TrEMBL
  A0A9L9PY64_HUMAN UniProtKB/TrEMBL
  A8K4I1 ENTREZGENE, UniProtKB/TrEMBL
  B4DTS9 ENTREZGENE
  F8W7D4_HUMAN UniProtKB/TrEMBL
  K7EMC6_HUMAN UniProtKB/TrEMBL
  P15151 ENTREZGENE
  P15152 ENTREZGENE
  PVR_HUMAN UniProtKB/Swiss-Prot
  Q15267 ENTREZGENE
  Q15268 ENTREZGENE
  Q96BJ1 ENTREZGENE
UniProt Secondary B4DTS9 UniProtKB/Swiss-Prot
  P15152 UniProtKB/Swiss-Prot
  Q15267 UniProtKB/Swiss-Prot
  Q15268 UniProtKB/Swiss-Prot
  Q96BJ1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-03-19 PVR  PVR cell adhesion molecule  PVR  poliovirus receptor  Symbol and/or name change 5135510 APPROVED