Gene: Ebp (EBP, cholestenol delta-isomerase) Rattus norvegicus
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Symbol: Ebp
Name: EBP, cholestenol delta-isomerase
Description: ENCODES a protein that exhibits C-8 sterol isomerase activity; steroid delta-isomerase activity (ortholog); INVOLVED IN cholesterol biosynthetic process; hemopoiesis (ortholog); sterol biosynthetic process (ortholog); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; ASSOCIATED WITH autistic disorder (ortholog); autosomal recessive congenital ichthyosis (ortholog); chondrodysplasia punctata (ortholog); FOUND IN intracellular membrane-bounded organelle; endoplasmic reticulum (ortholog); nuclear envelope (ortholog); INTERACTS WITH 1,2,4-trimethylbenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene
AGR Description: Exhibits C-8 sterol isomerase activity; involved in cholesterol biosynthetic process; localizes to the intracellular membrane-bounded organelle; orthologous to human EBP (EBP cholestenol delta-isomerase).
Merged Description: Exhibits C-8 sterol isomerase activity; involved in cholesterol biosynthetic process; localizes to the intracellular membrane-bounded organelle; orthologous to human EBP (EBP cholestenol delta-isomerase); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase; cholestenol Delta-isomerase; D8-D7 sterol isomerase; delta(8)-Delta(7) sterol isomerase; emopamil binding protein (sterol isomerase); emopamil-binding protein; phenylalkylamine Ca2+ antagonist (emopamil) binding protein; sterol 8-isomerase
Orthologs:
Homo sapiens (human) : EBP (EBP cholestenol delta-isomerase)  HGNC  Alliance
Mus musculus (house mouse) : Ebp (phenylalkylamine Ca2+ antagonist (emopamil) binding protein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ebp (EBP cholestenol delta-isomerase)
Pan paniscus (bonobo/pygmy chimpanzee) : EBP (EBP cholestenol delta-isomerase)
Canis lupus familiaris (dog) : EBP (EBP cholestenol delta-isomerase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ebp (EBP cholestenol delta-isomerase)
Sus scrofa (pig) : EBP (EBP cholestenol delta-isomerase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X15,049,394 - 15,055,782 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X15,832,710 - 15,839,093 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X26,331,199 - 26,337,542 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X26,384,667 - 26,391,010 (+)NCBI
CeleraX14,384,941 - 14,391,269 (+)NCBICelera
Cytogenetic MapXq12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ebp
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620957
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.