EBP (EBP cholestenol delta-isomerase) - Rat Genome Database

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Gene: EBP (EBP cholestenol delta-isomerase) Pan paniscus
Analyze
Symbol: EBP
Name: EBP cholestenol delta-isomerase
RGD ID: 11964038
Description: ENCODES a protein that exhibits C-8 sterol isomerase activity (ortholog); identical protein binding (ortholog); INVOLVED IN cholesterol biosynthetic process (ortholog); cholesterol metabolic process (ortholog); hemopoiesis (ortholog); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; ASSOCIATED WITH autistic disorder (ortholog); chondrodysplasia punctata (ortholog); congenital disorder of glycosylation type IIm (ortholog); FOUND IN nuclear envelope (ortholog); nuclear membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase; EBP, cholestenol delta-isomerase; emopamil binding protein (sterol isomerase)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X50,010,179 - 50,017,556 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X50,014,011 - 50,020,928 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X40,820,042 - 40,826,957 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X48,683,531 - 48,690,829 (+)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
EBP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X50,010,179 - 50,017,556 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X50,014,011 - 50,020,928 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X40,820,042 - 40,826,957 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X48,683,531 - 48,690,829 (+)NCBIpanpan1.1PanPan1.1panPan2
EBP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X48,521,808 - 48,528,716 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX48,521,799 - 48,528,716 (+)EnsemblGRCh38hg38GRCh38
GRCh37X48,380,196 - 48,387,104 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X48,265,201 - 48,272,048 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X48,136,510 - 48,143,356NCBI
CeleraX53,278,627 - 53,285,567 (-)NCBICelera
Cytogenetic MapXp11.23NCBI
HuRefX46,043,290 - 46,050,391 (+)NCBIHuRef
CHM1_1X48,411,425 - 48,418,366 (+)NCBICHM1_1
T2T-CHM13v2.0X47,930,820 - 47,937,730 (+)NCBIT2T-CHM13v2.0
Ebp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X8,051,568 - 8,059,751 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX8,051,568 - 8,059,751 (-)EnsemblGRCm39 Ensembl
GRCm38X8,185,329 - 8,193,512 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX8,185,329 - 8,193,512 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X7,762,457 - 7,770,638 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X7,342,290 - 7,350,471 (-)NCBIMGSCv36mm8
CeleraX3,276,541 - 3,284,699 (+)NCBICelera
Cytogenetic MapXA1.1NCBI
cM MapX3.7NCBI
Ebp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X16,971,372 - 16,977,782 (+)NCBIGRCr8
mRatBN7.2X14,299,427 - 14,305,826 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX14,299,448 - 14,305,826 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX19,112,990 - 19,119,361 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X20,963,718 - 20,970,092 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X17,228,913 - 17,235,289 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X15,049,394 - 15,055,782 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX15,049,462 - 15,055,781 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X15,832,710 - 15,839,093 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X26,331,199 - 26,337,542 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X26,384,667 - 26,391,010 (+)NCBI
CeleraX14,384,941 - 14,391,269 (+)NCBICelera
Cytogenetic MapXq12NCBI
Ebp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495554392,122 - 98,370 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495554392,553 - 98,370 (+)NCBIChiLan1.0ChiLan1.0
PORCN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X41,774,857 - 41,779,474 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX41,762,692 - 41,779,476 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX16,151,069 - 16,155,685 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X42,014,717 - 42,019,084 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX42,014,187 - 42,019,315 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X41,897,937 - 41,902,543 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X41,886,230 - 41,890,855 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X41,979,795 - 41,984,410 (+)NCBIUU_Cfam_GSD_1.0
Ebp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X34,268,094 - 34,275,579 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936721509,374 - 515,918 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936721508,716 - 515,968 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EBP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX42,670,633 - 42,678,570 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X42,670,592 - 42,678,571 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X47,619,482 - 47,627,465 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EBP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X45,652,398 - 45,660,551 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX45,653,356 - 45,660,291 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607611,104,334 - 11,112,368 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ebp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624893341,129 - 347,717 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624893340,843 - 346,560 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_034949531   ⟹   XP_034805422
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X50,010,639 - 50,017,556 (+)NCBI
NHGRI_mPanPan1X50,014,011 - 50,020,928 (+)NCBI
Mhudiblu_PPA_v0X40,820,042 - 40,826,957 (+)NCBI
RefSeq Acc Id: XM_034949533   ⟹   XP_034805424
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X50,010,654 - 50,017,556 (+)NCBI
NHGRI_mPanPan1X50,014,028 - 50,020,928 (+)NCBI
Mhudiblu_PPA_v0X40,820,054 - 40,826,957 (+)NCBI
RefSeq Acc Id: XM_055106608   ⟹   XP_054962583
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X50,010,179 - 50,017,556 (+)NCBI
NHGRI_mPanPan1X50,014,061 - 50,020,928 (+)NCBI
RefSeq Acc Id: XM_063601622   ⟹   XP_063457692
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X50,010,664 - 50,017,556 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034805422 (Get FASTA)   NCBI Sequence Viewer  
  XP_034805424 (Get FASTA)   NCBI Sequence Viewer  
  XP_054962583 (Get FASTA)   NCBI Sequence Viewer  
  XP_063457692 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000037892.1
Reference Protein Sequences
RefSeq Acc Id: XP_034805422   ⟸   XM_034949531
- UniProtKB: A0A2R9CI46 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034805424   ⟸   XM_034949533
- UniProtKB: A0A2R9CI46 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054962583   ⟸   XM_055106608
- UniProtKB: A0A2R9CI46 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063457692   ⟸   XM_063601622
Protein Domains
EXPERA


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000041670 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000060794.1 UniProtKB/TrEMBL
InterPro EBP UniProtKB/TrEMBL
  EXPERA UniProtKB/TrEMBL
NCBI Gene EBP ENTREZGENE
PANTHER 3-BETA-HYDROXYSTEROID-DELTA(8),DELTA(7)-ISOMERASE UniProtKB/TrEMBL
  STEROL ISOMERASE UniProtKB/TrEMBL
Pfam EBP UniProtKB/TrEMBL
UniProt A0A2R9CI46 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-29 EBP  EBP cholestenol delta-isomerase    EBP, cholestenol delta-isomerase  Symbol and/or name change 5135510 APPROVED
2018-05-15 EBP  EBP, cholestenol delta-isomerase    emopamil binding protein (sterol isomerase)  Symbol and/or name change 5135510 APPROVED