Bp64 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Bp64 (Blood pressure QTL 64) Rattus norvegicus

Symbol: Bp64
Name: Blood pressure QTL 64
RGD ID: 70165
Trait: arterial blood pressure trait   (VT:2000000)    
Measurement Type: systolic blood pressure   (CMO:0000004)    
LOD Score: 5.2
P Value: Not Available
Variance: 7.2
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8X4,001,493 - 44,939,387RGD_MAPPER_PIPELINE
mRatBN7.2X1,448,129 - 31,706,553RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0X1,662,609 - 33,443,848RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0X2,456,588 - 33,791,311RGDRnor5.0
RGSC_v3.4X30,326,177 - 52,447,691RGDRGSC3.4
RGSC_v3.1X30,379,696 - 52,501,160RGD
Cross Type: F2
Strains Crossed: SBH/Ygl SBN/Ygl 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp64Rathypertension  IDA 69713 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp64Ratincreased systemic arterial blood pressure  QTM 69713 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp64Ratsystolic blood pressure  IDA 697131% NaCl in waterRGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp64Ratcontrolled sodium content drinking water  IDA 697131% NaCl in waterRGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp64Rattail cuff photoplethysmography  IDA 697131% NaCl in waterRGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp64RatSBH/Ygl  IEA 69713 RGD 
Bp64RatSBN/Ygl  IEA 69713 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Bp64Ratarterial blood pressure trait  IDA 697131% NaCl in waterRGD 


#
Reference Title
Reference Citation
1. QTL Data Transfer QTL data import from the RatMap database
2. Role of chromosome X in the Sabra rat model of salt-sensitive hypertension. Yagil C, etal., Hypertension 1999 Jan;33(1 Pt 2):261-5.


1 to 20 of 384 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1303052Usp11ubiquitin specific peptidase 11X14733491489520Rat
620584Cdk16cyclin-dependent kinase 16X14928141504309Rat
1359327Uba1ubiquitin-like modifier activating enzyme 1X15087001530677Rat
631366Rbm10RNA binding motif protein 10X15403991572571Rat
1563698Ndufb11NADH:ubiquinone oxidoreductase subunit B11X15728051575063Rat
41084699LOC120099502U2 spliceosomal RNAX15765731576750Rat
41340321Foxn3-ps1forkhead box N3, pseudogene 1X15905401593962Rat
3560RgnregucalcinX16190301634456Rat
1564855Ruvbl1-ps1RuvB-like AAA ATPase 1, pseudogene 1X16401381641886Rat
1563945Jade3jade family PHD finger 3X16688731848781Rat
1565124Rp2RP2 activator of ARL3 GTPaseX18725821916704Rat
1565634Rpl7-ps28ribosomal protein L7, pseudogene 28X19754051976133Rat
1582764Slc25a39-ps2solute carrier family 25 member 39, pseudogene 2X19821191983242Rat
2325118Egln1-ps1egl-9 family hypoxia-inducible factor 1, pseudogene 1X21921432195194Rat
1561385Slc9a7solute carrier family 9 member A7X22140642395052Rat
41388570Actb-ps7actin, beta, pseudogene 7X22811102282237Rat
1303028Chst7carbohydrate sulfotransferase 7X23962602432828Rat
1582752Actb-ps8actin, beta, pseudogene 8X24804892481616Rat
7576093Rcc1-ps1regulator of chromosome condensation 1, pseudogene 1X24860512499797Rat
40998145LOC120099483small nucleolar RNA SNORA48X26886362688779Rat

1 to 20 of 384 rows
1 to 20 of 388 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10692DXWox17203X3103514431035347Ratregion
10943DXMit2277X1704117517041452Ratregion
10944DXWox5111X1704124517041356Ratregion
11080DXMgh5138X1951095319511091Ratregion
11080DXMgh5138X1951095319511180Ratregion
11081DXArb5301X1951077019511071Ratregion
11081DXArb5301X1951077019511180Ratregion
11082DXWox4135X1951095519511090Ratregion
11082DXWox4135X1951095519511180Ratregion
11167DXWox6144X2697607526976219Ratregion
11236DXWox11136X16237151623851Ratregion
34148DXMgh8122X2508866425088786Ratregion
34451DXMgh4117X2180716121807280Ratregion
34559DXMgh12199X3170655331706766Ratregion
11371DXMgh1144X1486545814865602Ratregion
11372DXWox1289X1486554514865582Ratregion
11494DXWox20202X1344236613442570Ratregion
33567DXMit1138X1115443711154575Ratregion
36079DXRat3137X1051890610519043Ratregion
36111DXRat8161X2099094720991088Ratregion
1 to 20 of 388 rows

Flank 1: (DXMgh12)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X31,706,553 - 31,706,766 (+)MAPPER
Rnor_6.0X33,443,848 - 33,444,058NCBI
Rnor_5.0X33,791,311 - 33,791,521UniSTS
RGSC_v3.4X52,447,478 - 52,447,691RGD
RGSC_v3.4X52,447,479 - 52,447,691UniSTS
RGSC_v3.1X52,500,947 - 52,501,160RGD
CeleraX32,020,448 - 32,020,650UniSTS
RH 3.4 MapX443.0UniSTS
RH 3.4 MapX443.0RGD
RH 2.0 Map21334.2RGD
Cytogenetic MapXq21UniSTS
Peak: (DXRat8)
Rat AssemblyChrPosition (strand)Source
GRCr8X24,470,360 - 24,470,521 (+)Marker Load Pipeline
mRatBN7.2X20,990,947 - 20,991,088 (+)MAPPER
Rnor_6.0X21,592,623 - 21,592,783NCBI
Rnor_5.0X21,859,080 - 21,859,240UniSTS
RGSC_v3.4X41,386,788 - 41,387,080RGD
RGSC_v3.4X41,386,879 - 41,387,039UniSTS
RGSC_v3.1X41,440,348 - 41,440,508RGD
CeleraX21,272,130 - 21,272,290UniSTS
RH 3.4 MapX186.31UniSTS
RH 3.4 MapX186.31RGD
RH 2.0 Map21223.4RGD
SHRSP x BN MapX6.8999RGD
FHH x ACI MapX7.93RGD
Cytogenetic MapXq21UniSTS
Flank 2: (DXRat2)
Rat AssemblyChrPosition (strand)Source
GRCr8X4,001,493 - 4,001,650 (+)Marker Load Pipeline
mRatBN7.2X1,447,972 - 1,448,129 (+)MAPPER
Rnor_6.0X1,662,453 - 1,662,609NCBI
Rnor_5.0X2,456,432 - 2,456,588UniSTS
SHRSP x BN MapX0.0RGD
SHRSP x BN MapX0.0UniSTS


1 to 10 of 12 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1598873Memor2Memory QTL 22.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)X2099094741052531Rat
70165Bp64Blood pressure QTL 645.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X144812931706553Rat
1298071Edpm12Estrogen-dependent pituitary mass QTL 123.2pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)X292789847927898Rat
2290375Gluco34Glucose level QTL 342.75blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)X2099094741203591Rat
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X143491017Rat
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
70166Bp65Blood pressure QTL 655.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X144797211374346Rat
10755455Coatc13Coat color QTL 130coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7440600049406000Rat
631666Iddm5Insulin dependent diabetes mellitus QTL 5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X449454949494549Rat
634325Bw13Body weight QTL 130body mass (VT:0001259)body weight (CMO:0000012)X144797220991088Rat

1 to 10 of 12 rows


Database
Acc Id
Source(s)
NCBI Gene Bp64

Note Type Note Reference
qtl_general QTL identifies a region containing a gene or genes that contribute to salt susceptibility in females but not in males 69713
qtl_general number of animals used: 707 F2 animals 69713
qtl_general software used: MAPMAKER/QTL 69713
qtl_general measurement method: basal blood pressure was measured at 6 weeks then 1%NaCl was given in drinking water; after 4 weeks systolic blood pressure was measured 69713