Gpr143 (G protein-coupled receptor 143)

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Gene: Gpr143 (G protein-coupled receptor 143) Rattus norvegicus

Analyze

Symbol:

Gpr143

Name:

G protein-coupled receptor 143

RGD ID:

1565799

Description:

Predicted to enable L-DOPA receptor activity; amino acid binding activity; and dopamine binding activity. Predicted to be involved in several processes, including intracellular signal transduction; melanosome organization; and melanosome transport. Predicted to be located in several cellular components, including apical plasma membrane; lysosomal membrane; and melanosome. Predicted to be active in melanosome membrane and plasma membrane. Human ortholog(s) of this gene implicated in congenital nystagmus 6. Orthologous to human GPR143 (G protein-coupled receptor 143); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; copper atom.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

G-protein coupled receptor 143; LOC302619; RGD1565799; similar to Oa1

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GPR143 (G protein-coupled receptor 143)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Gpr143 (G protein-coupled receptor 143)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gpr143 (G protein-coupled receptor 143)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GPR143 (G protein-coupled receptor 143)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GPR143 (G protein-coupled receptor 143)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gpr143 (G protein-coupled receptor 143)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GPR143 (G protein-coupled receptor 143)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GPR143 (G protein-coupled receptor 143)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gpr143 (G protein-coupled receptor 143)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	GPR143 (G protein-coupled receptor 143)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Gpr143 (G protein-coupled receptor 143)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	gpr143 (G protein-coupled receptor 143)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	gpr143	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	X	22,002,914 - 22,027,720 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	22,002,914 - 22,027,715 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	22,908,314 - 22,933,122 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	X	26,329,287 - 26,354,095 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	X	22,584,854 - 22,609,647 (+)	NCBI	Rnor_WKY
Rnor_6.0	X	23,668,363 - 23,693,162 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	23,668,363 - 23,693,162 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	24,084,931 - 24,109,730 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	42,481,440 - 42,506,239 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	22,403,114 - 22,427,887 (+)	NCBI		Celera
Cytogenetic Map	X	q13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Albinism (ISO)

autistic disorder (ISO)

congenital nystagmus 6 (ISO)

genetic disease (ISO)

Neurodevelopmental Disorders (ISO)

ocular albinism (ISS)

Ocular Albinism Type 1 (ISO)

pathologic nystagmus (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

arsenite(3-) (ISO)

belinostat (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

calcitriol (ISO)

copper atom (EXP)

copper(0) (EXP)

Cuprizon (EXP)

dorsomorphin (ISO)

entinostat (ISO)

isotretinoin (ISO)

pentanal (ISO)

propanal (ISO)

resveratrol (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sunitinib (ISO)

testosterone (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

calcium-mediated signaling using intracellular calcium source (ISO)

G protein-coupled receptor signaling pathway (IBA,ISO)

melanosome localization (ISO)

melanosome organization (IBA,ISO)

melanosome transport (ISO)

neuropeptide signaling pathway (IEA)

phosphatidylinositol-mediated signaling (ISO)

regulation of calcium-mediated signaling (IBA,ISO)

regulation of melanosome organization (ISO)

regulation of melanosome transport (ISO)

Cellular Component

apical plasma membrane (ISO)

Golgi apparatus (ISO)

lysosomal membrane (ISO)

melanosome (ISO)

melanosome membrane (IBA,ISO)

plasma membrane (IBA,ISO)

Molecular Function

dopamine binding (IBA,ISO)

G protein-coupled receptor activity (ISO)

L-DOPA binding (IBA,ISO)

L-DOPA receptor activity (IBA,ISO)

protein binding (ISO)

tyrosine binding (IBA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:10471510	PMID:16524428	PMID:16621890	PMID:18697795	PMID:18828673	PMID:19717472	PMID:24117106	PMID:25108060	PMID:35063136

Genomics

Comparative Map Data

Gpr143
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	X	22,002,914 - 22,027,720 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	22,002,914 - 22,027,715 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	22,908,314 - 22,933,122 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	X	26,329,287 - 26,354,095 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	X	22,584,854 - 22,609,647 (+)	NCBI	Rnor_WKY
Rnor_6.0	X	23,668,363 - 23,693,162 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	23,668,363 - 23,693,162 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	24,084,931 - 24,109,730 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	42,481,440 - 42,506,239 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	22,403,114 - 22,427,887 (+)	NCBI		Celera
Cytogenetic Map	X	q13	NCBI

GPR143
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	9,725,346 - 9,778,602 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	X	9,725,346 - 9,786,297 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	9,693,386 - 9,733,887 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	9,653,454 - 9,693,917 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	9,503,189 - 9,543,653	NCBI
Celera	X	13,865,374 - 13,905,925 (-)	NCBI		Celera
Cytogenetic Map	X	p22.2	NCBI
HuRef	X	7,525,733 - 7,566,160 (-)	NCBI		HuRef
CHM1_1	X	9,723,929 - 9,764,313 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	X	9,307,982 - 9,361,208 (-)	NCBI		T2T-CHM13v2.0

Gpr143
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	151,564,917 - 151,591,647 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	151,564,917 - 151,591,642 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	152,781,921 - 152,808,651 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	152,781,921 - 152,808,646 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	149,216,464 - 149,243,189 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	148,122,702 - 148,149,362 (+)	NCBI		MGSCv36	mm8
Celera	X	136,442,756 - 136,469,491 (-)	NCBI		Celera
Cytogenetic Map	X	F3	NCBI
cM Map	X	68.46	NCBI

Gpr143
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955499	7,909,019 - 7,928,431 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955499	7,900,276 - 7,953,847 (-)	NCBI	ChiLan1.0	ChiLan1.0

GPR143
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	X	11,532,585 - 11,573,122 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	2,357,835 - 2,398,389 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	9,609,597 - 9,650,069 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	9,609,598 - 9,650,075 (-)	Ensembl	panpan1.1		panPan2

GPR143
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	6,438,068 - 6,479,731 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	6,437,660 - 6,474,447 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	6,385,711 - 6,433,423 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	6,374,640 - 6,424,234 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	X	6,367,596 - 6,415,264 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	6,402,457 - 6,450,986 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	6,395,377 - 6,440,848 (-)	NCBI		UU_Cfam_GSD_1.0

Gpr143
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404953	4,141,453 - 4,180,471 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936644	196,263 - 235,305 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936644	196,344 - 236,659 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GPR143
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	X	6,242,296 - 6,276,654 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa11.1	Y	4,669,764 - 4,704,304 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	6,541,506 - 6,575,924 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GPR143
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	8,178,818 - 8,223,291 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	8,179,154 - 8,222,603 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666056	9,855,363 - 9,896,337 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gpr143
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624834	7,295,069 - 7,308,920 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624834	7,281,962 - 7,329,484 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Gpr143
46 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	53
Count of miRNA genes:	53
Interacting mature miRNAs:	53
Transcripts:	ENSRNOT00000004758
Prediction methods:	Miranda, Pita, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
731181	Uae27	Urinary albumin excretion QTL 27	2.7	0.0059	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	X	1	43491017	Rat
70165	Bp64	Blood pressure QTL 64	5.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	X	1448129	31706553	Rat
631204	Gluco15	Glucose level QTL 15		0.001	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	X	1623715	22646544	Rat
1298071	Edpm12	Estrogen-dependent pituitary mass QTL 12	3.2		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	X	2927898	47927898	Rat
10755455	Coatc13	Coat color QTL 13		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	4406000	49406000	Rat
631666	Iddm5	Insulin dependent diabetes mellitus QTL 5			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	X	4494549	49494549	Rat
61430	Cia18	Collagen induced arthritis QTL 18	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	14843113	120568734	Rat
71116	Niddm16	Non-insulin dependent diabetes mellitus QTL 16	7.81		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	X	15297802	60297802	Rat
1598873	Memor2	Memory QTL 2	2.5		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	X	20990947	41052531	Rat
2290375	Gluco34	Glucose level QTL 34	2.75		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	X	20990947	41203591	Rat

Markers in Region

RH134759

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	22,027,470 - 22,027,688 (+)	MAPPER	mRatBN7.2
Rnor_6.0	X	23,692,918 - 23,693,135	NCBI	Rnor6.0
Rnor_5.0	X	24,109,486 - 24,109,703	UniSTS	Rnor5.0
RGSC_v3.4	X	42,505,995 - 42,506,212	UniSTS	RGSC3.4
Celera	X	22,427,643 - 22,427,860	UniSTS
Cytogenetic Map	X	q21	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	nervous system	renal system	reproductive system	respiratory system
High
Medium
Low		2	1				49	24	30	11
Below cutoff	1	20	29	19	7	19	25	11	9

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039099643	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000374	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000004758 ⟹ ENSRNOP00000004758

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	22,002,914 - 22,027,715 (+)	Ensembl
Rnor_6.0 Ensembl	X	23,668,363 - 23,693,162 (+)	Ensembl

RefSeq Acc Id:

NM_001106958 ⟹ NP_001100428

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	X	22,002,914 - 22,027,715 (+)	NCBI
Rnor_6.0	X	23,668,363 - 23,693,162 (+)	NCBI
Rnor_5.0	X	24,084,931 - 24,109,730 (+)	NCBI
RGSC_v3.4	X	42,481,440 - 42,506,239 (+)	RGD
Celera	X	22,403,114 - 22,427,887 (+)	RGD

Sequence:

show sequence

GCCCAGCACCTGACCAGGAAAAGCTGTGGGTTCTGCAGACCAGAGACCGGTCCGTGAGCAAGAC
CAATGGCCTCCCCGCGCCTGGGAATCTTCTGCTGCCCTTCGTGGGATGCAGCCACACAGCTGGT
GCTGACCTTCCAACCGCGGGTGTTCCATGCGCTGTGTCTGGGCAGCGGCGCCCTCCGCCTGGTG
CTTGGCCTCCTTCAGCTCCTAACAGGGCGCCGATCTGTTGGTCACAGGGCGCCTGCGACAACCC
CAGCAGCCTCAGTCCACATCCTTCGTGCTGCCACCGCCTGTGATTTGCTTGGCTGCCTGGGAAT
CGTTATCAGGTCCACAGTGTGGATAGCCTACCCAGAATTCATTGAAAACATTTCCAATATGAAT
GGAACAGACATTTGGCCTACTGCTTTCTGTGTCGGGAGTGCAATGTGGATCCAGCTGTTGTACA
GTGCCTGCTTCTGGTGGCTCTTCTGCTATGCAGTTGATGTATACTTGGTGATCAGGAGATCAGC
AGGACGGAGCACCATCCTGCTGTACCACATCATGGCCTGGGGCCTGCCTGTGCTGCTCTGTGTG
GAAGGTGCAGTCATGCTTTATTACCCTTCTGTGTCCAGGTGTGAGAGAGGCCTGGACCATGCCA
TCCCCCATTATGTCACCACATACTTGCCACTTATGCTTGTCCTTGTGGCCAACCCGATCCTGTT
TCACAAGACAGTGATTTCAGTGGCCTCTTTACTGAAAGGACGAAAAGGTGTTTATACAGAGAAT
GAGAGATTGATGGGGGCCGTGATCAAGACCCGGTTTTTCAAAATAATGCTGGTGTTAATTGCAT
GTTGGTTGTCCAATATCATCAATGAATGTCTTTTGTTCTACCTTGAAATGCAACCAGATACCCA
TGGAGGCTCTCTGAAACGCATCCAGAATGCAGCCAGGACCACATGGTTTATTATGGGAATATTG
AATCCATCTCAAGGACTTCTCTTGTCTCTGGCCTTCTATGGCTGGACAGGATGCAGCCTGGATG
TCCATGCTCCCAAGATGGTGATTCAGTGGGAAACAATGACTGCCTCGGCTGCTGAGGGCACATA
TCAGACCCCTGAGGGTTCCTGTGTGCCCCATCAAAACCCCAGGAAGGTGGTGTGTGTTGGGGGG
CACACTTCTGATGAGGTGCTGAGTATTTTGTCTGAAGGTTCGGATGCTAGCACTGTTGAAATCC
ATACTGCAACTGGGTCCCACAACATAAAGGAAGTTGACTCCATTTCCCAAGCCCAGGGGGATCT
CTGAATGGATGGGATGGGGGCCAGACATCCCTGTTTTTCAGGTTCTGTGTCTTGTTGTTTTGGA
TTGTGTTCTTGCCTTCCTTCCTATCACAGTGCTGCCATGATGTAGCATCCTTCAAATTCCACTT
TGGTCACCATAGAGGAGCTCACTGAGGATGGCCTTTATGCTGGGAGAAACAACACACCAGAACT
TGGACATGGAAAATTTCCTCTAGAACATTCAGTGTCACCTCTTGACTTTTAATTACCCCTTGGA
CTTTTACTAAGGCCAGTTGTAGTGCTTAAGTGCCAGACCCAAATTCTTGAGAAAATAGTTAAAT
AAAGTCATTGTG

hide sequence

RefSeq Acc Id:

XM_039099643 ⟹ XP_038955571

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	X	22,003,093 - 22,027,720 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001100428	(Get FASTA)	NCBI Sequence Viewer
	XP_038955571	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL90600	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001100428 ⟸ NM_001106958

- UniProtKB:

D4A082 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MASPRLGIFCCPSWDAATQLVLTFQPRVFHALCLGSGALRLVLGLLQLLTGRRSVGHRAPATTP
AASVHILRAATACDLLGCLGIVIRSTVWIAYPEFIENISNMNGTDIWPTAFCVGSAMWIQLLYS
ACFWWLFCYAVDVYLVIRRSAGRSTILLYHIMAWGLPVLLCVEGAVMLYYPSVSRCERGLDHAI
PHYVTTYLPLMLVLVANPILFHKTVISVASLLKGRKGVYTENERLMGAVIKTRFFKIMLVLIAC
WLSNIINECLLFYLEMQPDTHGGSLKRIQNAARTTWFIMGILNPSQGLLLSLAFYGWTGCSLDV
HAPKMVIQWETMTASAAEGTYQTPEGSCVPHQNPRKVVCVGGHTSDEVLSILSEGSDASTVEIH
TATGSHNIKEVDSISQAQGDL

hide sequence

RefSeq Acc Id:

ENSRNOP00000004758 ⟸ ENSRNOT00000004758

RefSeq Acc Id:	XP_038955571 ⟸ XM_039099643
- Peptide Label:	isoform X1

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A082-F1-model_v2	AlphaFold	D4A082	1-405	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1565799	AgrOrtholog
BioCyc Gene	G2FUF-2706	BioCyc
Ensembl Genes	ENSRNOG00000003543	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000004758	ENTREZGENE
	ENSRNOP00000004758.4	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000004758	ENTREZGENE
	ENSRNOT00000004758.6	UniProtKB/TrEMBL
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/TrEMBL
InterPro	Ocular_alb1	UniProtKB/TrEMBL
KEGG Report	rno:302619	UniProtKB/TrEMBL
NCBI Gene	302619	ENTREZGENE
PANTHER	G-PROTEIN COUPLED RECEPTOR 143	UniProtKB/TrEMBL
	PTHR15177	UniProtKB/TrEMBL
Pfam	Ocular_alb	UniProtKB/TrEMBL
PhenoGen	Gpr143	PhenoGen
PRINTS	OCULARALBNSM	UniProtKB/TrEMBL
UniProt	D4A082	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Gpr143	G protein-coupled receptor 143	Gpr143_predicted	G protein-coupled receptor 143 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-30	Gpr143_predicted	G protein-coupled receptor 143 (predicted)	RGD1565799_predicted	similar to Oa1 (predicted)	Symbol and Name updated	1299863	APPROVED
2006-03-07	RGD1565799_predicted	similar to Oa1 (predicted)	LOC302619	similar to Oa1	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC302619	similar to Oa1			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

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