Frmpd4 (FERM and PDZ domain containing 4) - Rat Genome Database

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Gene: Frmpd4 (FERM and PDZ domain containing 4) Rattus norvegicus
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Symbol: Frmpd4
Name: FERM and PDZ domain containing 4
RGD ID: 1566031
Description: Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity. Involved in postsynaptic actin cytoskeleton organization. Is active in glutamatergic synapse and postsynaptic density. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 104. Orthologous to human FRMPD4 (FERM and PDZ domain containing 4); INTERACTS WITH 17alpha-ethynylestradiol; 3,4-methylenedioxymethamphetamine; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: FERM and PDZ domain-containing protein 4; LOC302656; RGD1566031; similar to KIAA0316 protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X29,739,834 - 30,386,917 (+)NCBIGRCr8
mRatBN7.2X25,853,849 - 26,814,642 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX25,853,934 - 26,814,637 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX27,701,139 - 27,831,285 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X31,119,411 - 31,249,752 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X27,342,396 - 27,472,510 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X27,231,648 - 28,206,890 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX28,072,826 - 28,204,260 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X27,955,922 - 28,600,017 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X47,683,734 - 47,814,085 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX27,055,940 - 27,185,801 (+)NCBICelera
Cytogenetic MapXq13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Preso, a novel PSD-95-interacting FERM and PDZ domain protein that regulates dendritic spine morphogenesis. Lee HW, etal., J Neurosci. 2008 Dec 31;28(53):14546-56. doi: 10.1523/JNEUROSCI.3112-08.2008.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:22074847   PMID:22561452   PMID:37442439  


Genomics

Comparative Map Data
Frmpd4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X29,739,834 - 30,386,917 (+)NCBIGRCr8
mRatBN7.2X25,853,849 - 26,814,642 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX25,853,934 - 26,814,637 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX27,701,139 - 27,831,285 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X31,119,411 - 31,249,752 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X27,342,396 - 27,472,510 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X27,231,648 - 28,206,890 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX28,072,826 - 28,204,260 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X27,955,922 - 28,600,017 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X47,683,734 - 47,814,085 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX27,055,940 - 27,185,801 (+)NCBICelera
Cytogenetic MapXq13NCBI
FRMPD4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X11,822,439 - 12,724,523 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX11,822,423 - 12,724,523 (+)EnsemblGRCh38hg38GRCh38
GRCh37X11,840,558 - 12,742,642 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X12,066,506 - 12,650,450 (+)NCBINCBI36Build 36hg18NCBI36
CeleraX16,274,012 - 16,856,608 (+)NCBICelera
Cytogenetic MapXp22.2NCBI
HuRefX9,927,416 - 10,509,157 (+)NCBIHuRef
CHM1_1X12,187,174 - 12,773,028 (+)NCBICHM1_1
T2T-CHM13v2.0X11,404,988 - 12,305,982 (+)NCBIT2T-CHM13v2.0
Frmpd4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X166,254,297 - 167,360,230 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX166,254,305 - 167,360,227 (-)EnsemblGRCm39 Ensembl
GRCm38X167,471,306 - 168,577,241 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX167,471,309 - 168,577,231 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X163,909,241 - 165,015,165 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X162,815,414 - 163,921,338 (-)NCBIMGSCv36mm8
CeleraX150,648,006 - 151,744,590 (-)NCBICelera
Cytogenetic MapXF5NCBI
cM MapX78.36NCBI
Frmpd4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955544584,686 - 1,151,938 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955544586,991 - 1,152,195 (-)NCBIChiLan1.0ChiLan1.0
FRMPD4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X13,926,325 - 14,508,937 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X13,929,974 - 14,512,604 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X4,450,486 - 5,336,784 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X12,399,567 - 12,624,370 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX12,399,479 - 12,622,978 (+)Ensemblpanpan1.1panPan2
FRMPD4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X8,663,015 - 9,229,269 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX8,664,739 - 9,226,025 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX8,619,305 - 9,185,368 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X8,616,367 - 9,181,282 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX8,371,923 - 9,180,672 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X8,599,446 - 9,165,435 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X8,635,573 - 9,205,459 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X8,631,669 - 9,197,726 (+)NCBIUU_Cfam_GSD_1.0
Frmpd4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X1,690,540 - 2,469,067 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364701,923,835 - 2,470,564 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364701,923,328 - 2,469,067 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FRMPD4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX8,542,382 - 9,438,821 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X8,625,039 - 9,451,433 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X10,224,041 - 10,300,128 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FRMPD4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X10,364,458 - 11,213,356 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX10,996,515 - 11,214,725 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605612,408,452 - 13,006,309 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Frmpd4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248821,552,801 - 2,150,894 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248821,554,597 - 2,152,481 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Frmpd4
4599 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:29
Count of miRNA genes:22
Interacting mature miRNAs:28
Transcripts:ENSRNOT00000039796
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X143491017Rat
70165Bp64Blood pressure QTL 645.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X144812931706553Rat
1298071Edpm12Estrogen-dependent pituitary mass QTL 123.2pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)X292789847927898Rat
10755455Coatc13Coat color QTL 130coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7440600049406000Rat
631666Iddm5Insulin dependent diabetes mellitus QTL 5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X449454949494549Rat
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
71116Niddm16Non-insulin dependent diabetes mellitus QTL 167.81blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X1529780260297802Rat
1598873Memor2Memory QTL 22.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)X2099094741052531Rat
2290375Gluco34Glucose level QTL 342.75blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)X2099094741203591Rat

Markers in Region
DXRat24  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0X27,696,275 - 27,696,404NCBIRnor6.0
Rnor_5.0X28,096,483 - 28,096,659UniSTSRnor5.0
CeleraX26,693,788 - 26,693,938UniSTS
RH 3.4 MapX334.9UniSTS
RH 3.4 MapX334.9RGD
RH 2.0 Map21254.9RGD
FHH x ACI MapX9.03RGD
Cytogenetic MapXq21UniSTS
DXRat143  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X26,634,871 - 26,635,013 (+)MAPPERmRatBN7.2
Rnor_6.0X28,025,522 - 28,025,663NCBIRnor6.0
Rnor_5.0X28,422,769 - 28,422,910UniSTSRnor5.0
RGSC_v3.4X47,636,734 - 47,636,876RGDRGSC3.4
RGSC_v3.4X47,636,735 - 47,636,876UniSTSRGSC3.4
RGSC_v3.1X47,690,203 - 47,690,345RGD
CeleraX27,009,007 - 27,009,155UniSTS
FHH x ACI MapX12.33UniSTS
FHH x ACI MapX12.33RGD
Cytogenetic MapXq21UniSTS
DXRat124  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X26,634,843 - 26,635,104 (+)MAPPERmRatBN7.2
Rnor_6.0X28,025,494 - 28,025,754NCBIRnor6.0
Rnor_5.0X28,422,741 - 28,423,001UniSTSRnor5.0
RGSC_v3.4X47,636,706 - 47,636,967RGDRGSC3.4
RGSC_v3.4X47,636,707 - 47,636,967UniSTSRGSC3.4
RGSC_v3.1X47,690,176 - 47,690,436RGD
CeleraX27,008,979 - 27,009,224UniSTS
RH 3.4 MapX339.1RGD
RH 3.4 MapX339.1UniSTS
RH 2.0 Map21264.1RGD
SHRSP x BN MapX7.97RGD
Cytogenetic MapXq21UniSTS
DXGot23  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X26,440,728 - 26,440,937 (+)MAPPERmRatBN7.2
Rnor_6.0X27,830,258 - 27,830,466NCBIRnor6.0
Rnor_5.0X28,227,501 - 28,227,709UniSTSRnor5.0
RGSC_v3.4X47,438,309 - 47,438,518RGDRGSC3.4
RGSC_v3.4X47,438,310 - 47,438,518UniSTSRGSC3.4
RGSC_v3.1X47,491,779 - 47,491,987RGD
CeleraX26,815,220 - 26,815,428UniSTS
RH 3.4 MapX334.8UniSTS
RH 3.4 MapX334.8RGD
RH 2.0 Map21273.8RGD
Cytogenetic MapXq21UniSTS
DXGot20  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X26,666,219 - 26,666,399 (+)MAPPERmRatBN7.2
Rnor_6.0X28,057,043 - 28,057,222NCBIRnor6.0
Rnor_5.0X28,454,290 - 28,454,469UniSTSRnor5.0
RGSC_v3.4X47,668,079 - 47,668,259RGDRGSC3.4
RGSC_v3.4X47,668,080 - 47,668,259UniSTSRGSC3.4
RGSC_v3.1X47,721,549 - 47,721,728RGD
CeleraX27,040,286 - 27,040,465UniSTS
RH 3.4 MapX310.8UniSTS
RH 3.4 MapX310.8RGD
RH 2.0 Map21275.7RGD
Cytogenetic MapXq21UniSTS
DXGot18  
Rat AssemblyChrPosition (strand)SourceJBrowse
CeleraX26,700,876 - 26,701,116UniSTS
RH 3.4 MapX335.4RGD
RH 3.4 MapX335.4UniSTS
Cytogenetic MapXq21UniSTS
RH144489  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X26,253,167 - 26,253,271 (+)MAPPERmRatBN7.2
Rnor_6.0X27,641,965 - 27,642,068NCBIRnor6.0
Rnor_5.0X28,042,033 - 28,042,136UniSTSRnor5.0
RGSC_v3.4X46,962,852 - 46,962,955UniSTSRGSC3.4
CeleraX26,639,800 - 26,639,903UniSTS
RH 3.4 MapX334.7UniSTS
Cytogenetic MapXq21UniSTS
BF399596  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X26,212,557 - 26,212,652 (+)MAPPERmRatBN7.2
Rnor_6.0X27,601,446 - 27,601,540NCBIRnor6.0
Rnor_5.0X28,001,514 - 28,001,608UniSTSRnor5.0
RGSC_v3.4X46,921,289 - 46,921,383UniSTSRGSC3.4
CeleraX26,598,978 - 26,599,072UniSTS
RH 3.4 MapX334.1UniSTS
Cytogenetic MapXq21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 33
Low 2 31 16 36 10
Below cutoff 3 3 34 19 17 19 7 8 10 4 5 1 7

Sequence


RefSeq Acc Id: ENSRNOT00000039796   ⟹   ENSRNOP00000035028
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX25,853,934 - 26,811,971 (+)Ensembl
Rnor_6.0 EnsemblX28,072,826 - 28,204,260 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000096626   ⟹   ENSRNOP00000094044
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX26,169,141 - 26,811,971 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000104697   ⟹   ENSRNOP00000093782
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX26,392,393 - 26,811,971 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000112961   ⟹   ENSRNOP00000089628
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX26,167,996 - 26,814,637 (+)Ensembl
RefSeq Acc Id: NM_001106960   ⟹   NP_001100430
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X30,254,161 - 30,384,243 (+)NCBI
mRatBN7.2X26,681,876 - 26,811,971 (+)NCBI
Rnor_6.0X28,072,821 - 28,204,260 (+)NCBI
Rnor_5.0X27,955,922 - 28,600,017 (+)NCBI
RGSC_v3.4X47,683,734 - 47,814,085 (+)RGD
CeleraX27,055,940 - 27,185,801 (+)RGD
Sequence:
RefSeq Acc Id: XM_017601998   ⟹   XP_017457487
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X29,740,716 - 30,386,917 (+)NCBI
mRatBN7.2X26,168,372 - 26,814,642 (+)NCBI
Rnor_6.0X27,555,025 - 28,206,890 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017601999   ⟹   XP_017457488
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X29,739,834 - 30,386,917 (+)NCBI
mRatBN7.2X26,167,507 - 26,814,642 (+)NCBI
Rnor_6.0X27,554,661 - 28,206,890 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017602000   ⟹   XP_017457489
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X29,740,716 - 30,386,917 (+)NCBI
mRatBN7.2X26,168,372 - 26,814,642 (+)NCBI
Rnor_6.0X27,555,025 - 28,206,890 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039099649   ⟹   XP_038955577
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X29,740,648 - 30,386,917 (+)NCBI
mRatBN7.2X26,167,507 - 26,814,642 (+)NCBI
RefSeq Acc Id: XM_063279930   ⟹   XP_063136000
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X29,740,715 - 30,386,917 (+)NCBI
RefSeq Acc Id: XM_063279931   ⟹   XP_063136001
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X29,740,717 - 30,386,917 (+)NCBI
RefSeq Acc Id: XM_063279932   ⟹   XP_063136002
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X29,739,837 - 30,386,917 (+)NCBI
RefSeq Acc Id: NP_001100430   ⟸   NM_001106960
- UniProtKB: A0A8I6GKT4 (UniProtKB/TrEMBL),   A6K2F7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017457488   ⟸   XM_017601999
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017457489   ⟸   XM_017602000
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017457487   ⟸   XM_017601998
- Peptide Label: isoform X1
- UniProtKB: A0A8I6ALA6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000035028   ⟸   ENSRNOT00000039796
RefSeq Acc Id: XP_038955577   ⟸   XM_039099649
- Peptide Label: isoform X4
RefSeq Acc Id: ENSRNOP00000094044   ⟸   ENSRNOT00000096626
RefSeq Acc Id: ENSRNOP00000093782   ⟸   ENSRNOT00000104697
RefSeq Acc Id: ENSRNOP00000089628   ⟸   ENSRNOT00000112961
RefSeq Acc Id: XP_063136002   ⟸   XM_063279932
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063136000   ⟸   XM_063279930
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063136001   ⟸   XM_063279931
- Peptide Label: isoform X5
Protein Domains
FERM   PDZ   WW

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A3K7-F1-model_v2 AlphaFold D4A3K7 1-1705 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1566031 AgrOrtholog
BioCyc Gene G2FUF-2670 BioCyc
Ensembl Genes ENSRNOG00000004118 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000039796.6 UniProtKB/TrEMBL
  ENSRNOT00000096626.1 UniProtKB/TrEMBL
  ENSRNOT00000104697 ENTREZGENE
  ENSRNOT00000104697.1 UniProtKB/TrEMBL
  ENSRNOT00000112961.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.80.10 UniProtKB/TrEMBL
  2.20.70.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  2.30.42.10 UniProtKB/TrEMBL
InterPro Band_41_domain UniProtKB/TrEMBL
  FAK1-like_FERM_C UniProtKB/TrEMBL
  FERM/acyl-CoA-bd_prot_3-hlx UniProtKB/TrEMBL
  FERM_2 UniProtKB/TrEMBL
  FERM_central UniProtKB/TrEMBL
  FERM_domain UniProtKB/TrEMBL
  FRMPD1/3/4_FERM_C UniProtKB/TrEMBL
  PDZ/DHR/GLGF UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
  PH_dom-like UniProtKB/TrEMBL
  Ubiquitin-rel_dom UniProtKB/TrEMBL
  WW_dom UniProtKB/TrEMBL
  WW_dom_sf UniProtKB/TrEMBL
KEGG Report rno:302656 UniProtKB/TrEMBL
NCBI Gene 302656 ENTREZGENE
PANTHER FERM AND PDZ DOMAIN-CONTAINING PROTEIN 4 UniProtKB/TrEMBL
  FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER UniProtKB/TrEMBL
Pfam FERM_C_FAK1 UniProtKB/TrEMBL
  FERM_M UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
PhenoGen Frmpd4 PhenoGen
PROSITE FERM_3 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  WW_DOMAIN_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004118 RatGTEx
SMART B41 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
Superfamily-SCOP FERM_3-hlx UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  PH domain-like UniProtKB/TrEMBL
  SSF51045 UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
UniProt A0A8I6ALA6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ALF4_RAT UniProtKB/TrEMBL
  A0A8I6GKT4 ENTREZGENE, UniProtKB/TrEMBL
  A6K2F7 ENTREZGENE, UniProtKB/TrEMBL
  D4A3K7_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-07 Frmpd4  FERM and PDZ domain containing 4  RGD1566031_predicted  similar to KIAA0316 protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1566031_predicted  similar to KIAA0316 protein (predicted)  LOC302656  similar to KIAA0316 protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC302656  similar to KIAA0316 protein      Symbol and Name status set to provisional 70820 PROVISIONAL