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Gene: Tfe3 (transcription factor binding to IGHM enhancer 3) Rattus norvegicus
Symbol: Tfe3
Name: transcription factor binding to IGHM enhancer 3
RGD ID: 1559642
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein heterodimerization activity. Predicted to be involved in several processes, including negative regulation of cold-induced thermogenesis; positive regulation of brown fat cell differentiation; and regulation of osteoclast differentiation. Predicted to localize to cytosol and nucleoplasm. Human ortholog(s) of this gene implicated in renal cell carcinoma. Orthologous to human TFE3 (transcription factor binding to IGHM enhancer 3); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
Also known as: LOC317376; RGD1559642; similar to Tcfe3 protein; Tcfe3; transcription factor E3
Homo sapiens (human) : TFE3 (transcription factor binding to IGHM enhancer 3)  HGNC  Alliance
Mus musculus (house mouse) : Tfe3 (transcription factor E3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tfe3 (transcription factor binding to IGHM enhancer 3)
Pan paniscus (bonobo/pygmy chimpanzee) : TFE3 (transcription factor binding to IGHM enhancer 3)
Canis lupus familiaris (dog) : TFE3 (transcription factor binding to IGHM enhancer 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tfe3 (transcription factor binding to IGHM enhancer 3)
Sus scrofa (pig) : TFE3 (transcription factor binding to IGHM enhancer 3)
Chlorocebus sabaeus (African green monkey) : TFE3 (transcription factor binding to IGHM enhancer 3)
Heterocephalus glaber (naked mole-rat) : Tfe3 (transcription factor binding to IGHM enhancer 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0X15,574,579 - 15,587,826 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX15,575,934 - 15,587,419 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X16,355,812 - 16,369,002 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X26,768,875 - 26,781,006 (-)NCBIRGSC3.4rn4RGSC3.4
CeleraX14,814,215 - 14,827,305 (-)NCBICelera
Cytogenetic MapXq12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Tfe3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1559642
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.