Tfe3 (transcription factor binding to IGHM enhancer 3) - Rat Genome Database

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Gene: Tfe3 (transcription factor binding to IGHM enhancer 3) Rattus norvegicus
Analyze
Symbol: Tfe3
Name: transcription factor binding to IGHM enhancer 3
RGD ID: 1559642
Description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; E-box binding activity; and protein heterodimerization activity. Predicted to be involved in several processes, including negative regulation of cold-induced thermogenesis; positive regulation of brown fat cell differentiation; and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within positive regulation of DNA-templated transcription and regulation of osteoclast differentiation. Predicted to be located in cytosol; lysosomal membrane; and nucleoplasm. Human ortholog(s) of this gene implicated in renal cell carcinoma. Orthologous to human TFE3 (transcription factor binding to IGHM enhancer 3); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC317376; RGD1559642; similar to Tcfe3 protein; Tcfe3; transcription factor E3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X14,729,547 - 14,742,830 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX14,729,550 - 14,742,571 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX19,543,279 - 19,556,535 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X20,526,577 - 20,539,833 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X16,791,746 - 16,805,003 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X15,574,579 - 15,587,826 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX15,575,934 - 15,587,419 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X16,355,812 - 16,369,002 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X26,768,875 - 26,781,006 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX14,814,215 - 14,827,305 (-)NCBICelera
Cytogenetic MapXq12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
5-azacytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetylsalicylic acid  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
azathioprine  (ISO)
Benoxacor  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (ISO)
bisphenol F  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
chloroacetaldehyde  (ISO)
cisplatin  (ISO)
clodronic acid  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
cyclosporin A  (EXP,ISO)
cylindrospermopsin  (ISO)
cytarabine  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
fenofibrate  (EXP,ISO)
fenvalerate  (EXP)
fingolimod hydrochloride  (ISO)
flutamide  (EXP)
fonofos  (ISO)
gentamycin  (EXP)
glycochenodeoxycholic acid  (ISO)
ibuprofen  (EXP,ISO)
indometacin  (ISO)
ketamine  (EXP)
menadione  (ISO)
mercury dibromide  (ISO)
metformin  (EXP)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N-acetyl-L-cysteine  (ISO)
N-acetylsphingosine  (ISO)
nefazodone  (EXP)
nickel sulfate  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP,ISO)
parathion  (ISO)
pirinixic acid  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
T-2 toxin  (ISO)
temozolomide  (ISO)
terbufos  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
torin 1  (ISO)
trichloroethene  (EXP)
triptonide  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zebularine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO,ISS)
cytosol  (ISO)
lysosomal membrane  (ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,ISO,ISS)

References

References - curated
# Reference Title Reference Citation
1. A novel CLTC-TFE3 gene fusion in pediatric renal adenocarcinoma with t(X;17)(p11.2;q23). Argani P, etal., Oncogene. 2003 Aug 14;22(34):5374-8.
2. TFE3 controls lipid metabolism in adipose tissue of male mice by suppressing lipolysis and thermogenesis. Fujimoto Y, etal., Endocrinology. 2013 Oct;154(10):3577-88. doi: 10.1210/en.2013-1203. Epub 2013 Jul 24.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:11930005   PMID:15994295   PMID:16936731   PMID:21209915   PMID:22692423   PMID:26352760   PMID:27913603   PMID:29146937   PMID:32716134  


Genomics

Comparative Map Data
Tfe3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X14,729,547 - 14,742,830 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX14,729,550 - 14,742,571 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX19,543,279 - 19,556,535 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X20,526,577 - 20,539,833 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X16,791,746 - 16,805,003 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X15,574,579 - 15,587,826 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX15,575,934 - 15,587,419 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X16,355,812 - 16,369,002 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X26,768,875 - 26,781,006 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX14,814,215 - 14,827,305 (-)NCBICelera
Cytogenetic MapXq12NCBI
TFE3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X49,028,726 - 49,043,357 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX49,028,726 - 49,043,410 (-)EnsemblGRCh38hg38GRCh38
GRCh37X48,886,237 - 48,900,883 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X48,771,186 - 48,787,934 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X48,642,489 - 48,657,239NCBI
CeleraX52,763,508 - 52,778,256 (+)NCBICelera
Cytogenetic MapXp11.23NCBI
HuRefX46,544,091 - 46,558,358 (-)NCBIHuRef
CHM1_1X48,917,574 - 48,932,321 (-)NCBICHM1_1
T2T-CHM13v2.0X48,440,314 - 48,454,961 (-)NCBIT2T-CHM13v2.0
Tfe3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X7,628,769 - 7,641,441 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX7,628,799 - 7,641,441 (+)EnsemblGRCm39 Ensembl
GRCm38X7,762,530 - 7,775,202 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX7,762,560 - 7,775,202 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X7,339,787 - 7,352,328 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X6,919,676 - 6,932,158 (+)NCBIMGSCv36mm8
CeleraX3,695,480 - 3,708,004 (-)NCBICelera
Cytogenetic MapXA1.1NCBI
cM MapX3.5NCBI
Tfe3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955543547,037 - 561,073 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955543547,037 - 561,073 (-)NCBIChiLan1.0ChiLan1.0
TFE3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1X50,521,917 - 50,536,666 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X41,326,802 - 41,341,574 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X49,182,795 - 49,197,194 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX49,182,795 - 49,197,194 (-)Ensemblpanpan1.1panPan2
TFE3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X42,181,639 - 42,192,709 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX42,183,037 - 42,193,892 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX16,557,254 - 16,568,302 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X42,317,881 - 42,328,931 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX42,317,905 - 42,328,969 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X42,304,191 - 42,315,238 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X42,291,847 - 42,302,895 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X42,386,591 - 42,397,641 (-)NCBIUU_Cfam_GSD_1.0
Tfe3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X34,693,183 - 34,705,282 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936721933,404 - 945,725 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936721933,572 - 945,717 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TFE3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX43,100,032 - 43,116,227 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X43,100,375 - 43,116,377 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X47,948,307 - 47,964,209 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TFE3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X46,141,377 - 46,155,445 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX46,140,543 - 46,155,372 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607611,655,554 - 11,669,637 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tfe3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624893803,717 - 817,705 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624893803,717 - 817,700 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tfe3
57 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:140
Count of miRNA genes:74
Interacting mature miRNAs:79
Transcripts:ENSRNOT00000012829, ENSRNOT00000029776
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X143491017Rat
634325Bw13Body weight QTL 130body mass (VT:0001259)body weight (CMO:0000012)X144797220991088Rat
70165Bp64Blood pressure QTL 645.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X144812931706553Rat
631204Gluco15Glucose level QTL 150.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)X162371522646544Rat
1298071Edpm12Estrogen-dependent pituitary mass QTL 123.2pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)X292789847927898Rat
10755455Coatc13Coat color QTL 130coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7440600049406000Rat
631666Iddm5Insulin dependent diabetes mellitus QTL 5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X449454949494549Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 26 15 7 11 7 2 66 30 34 11
Low 1 17 42 34 8 34 8 9 8 5 7 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001271227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005497983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005497984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC130624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000012829   ⟹   ENSRNOP00000012830
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX14,729,552 - 14,742,571 (-)Ensembl
Rnor_6.0 EnsemblX15,575,934 - 15,587,419 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000100614   ⟹   ENSRNOP00000080433
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX14,729,550 - 14,741,456 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000104339   ⟹   ENSRNOP00000080987
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX14,729,552 - 14,742,571 (-)Ensembl
RefSeq Acc Id: NM_001271227   ⟹   NP_001258156
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X14,729,547 - 14,742,769 (-)NCBI
Rnor_6.0X15,574,579 - 15,587,698 (-)NCBI
Rnor_5.0X16,355,812 - 16,369,002 (-)NCBI
CeleraX14,814,215 - 14,827,305 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006256721   ⟹   XP_006256783
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X14,729,549 - 14,741,430 (-)NCBI
Rnor_6.0X15,574,579 - 15,586,379 (-)NCBI
Rnor_5.0X16,355,812 - 16,369,002 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006256722   ⟹   XP_006256784
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X14,729,549 - 14,742,764 (-)NCBI
Rnor_6.0X15,574,579 - 15,587,700 (-)NCBI
Rnor_5.0X16,355,812 - 16,369,002 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006256723   ⟹   XP_006256785
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X14,729,549 - 14,742,757 (-)NCBI
Rnor_6.0X15,574,579 - 15,587,699 (-)NCBI
Rnor_5.0X16,355,812 - 16,369,002 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006256727   ⟹   XP_006256789
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X14,729,549 - 14,741,641 (-)NCBI
Rnor_6.0X15,574,579 - 15,586,797 (-)NCBI
Rnor_5.0X16,355,812 - 16,369,002 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006256728   ⟹   XP_006256790
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X14,729,549 - 14,742,830 (-)NCBI
Rnor_6.0X15,574,579 - 15,587,826 (-)NCBI
Rnor_5.0X16,355,812 - 16,369,002 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006256729   ⟹   XP_006256791
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X14,729,549 - 14,742,473 (-)NCBI
Rnor_6.0X15,574,579 - 15,587,296 (-)NCBI
Rnor_5.0X16,355,812 - 16,369,002 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017602063   ⟹   XP_017457552
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X14,729,549 - 14,741,472 (-)NCBI
Rnor_6.0X15,574,579 - 15,587,150 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039099775   ⟹   XP_038955703
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X14,729,549 - 14,742,249 (-)NCBI
RefSeq Acc Id: XM_039099776   ⟹   XP_038955704
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X14,729,549 - 14,741,447 (-)NCBI
RefSeq Acc Id: XM_039099777   ⟹   XP_038955705
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X14,729,549 - 14,741,415 (-)NCBI
RefSeq Acc Id: XM_039099778   ⟹   XP_038955706
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X14,735,087 - 14,742,764 (-)NCBI
RefSeq Acc Id: XM_039099779   ⟹   XP_038955707
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X14,735,085 - 14,742,764 (-)NCBI
RefSeq Acc Id: XR_005497983
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X14,729,549 - 14,742,764 (-)NCBI
RefSeq Acc Id: XR_005497984
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X14,729,549 - 14,742,764 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001258156   ⟸   NM_001271227
- UniProtKB: D3ZAW6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256790   ⟸   XM_006256728
- Peptide Label: isoform X3
- UniProtKB: D3ZAW6 (UniProtKB/TrEMBL),   A0A8I5ZU56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256784   ⟸   XM_006256722
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZU56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256785   ⟸   XM_006256723
- Peptide Label: isoform X3
- UniProtKB: D3ZAW6 (UniProtKB/TrEMBL),   A0A8I5ZU56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256791   ⟸   XM_006256729
- Peptide Label: isoform X3
- UniProtKB: D3ZAW6 (UniProtKB/TrEMBL),   A0A8I5ZU56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256789   ⟸   XM_006256727
- Peptide Label: isoform X3
- UniProtKB: D3ZAW6 (UniProtKB/TrEMBL),   A0A8I5ZU56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256783   ⟸   XM_006256721
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZPP5 (UniProtKB/TrEMBL),   A0A8I5ZU56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017457552   ⟸   XM_017602063
- Peptide Label: isoform X3
- UniProtKB: D3ZAW6 (UniProtKB/TrEMBL),   A0A8I5ZU56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000012830   ⟸   ENSRNOT00000012829
RefSeq Acc Id: XP_038955703   ⟸   XM_039099775
- Peptide Label: isoform X3
- UniProtKB: D3ZAW6 (UniProtKB/TrEMBL),   A0A8I5ZU56 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955704   ⟸   XM_039099776
- Peptide Label: isoform X3
- UniProtKB: D3ZAW6 (UniProtKB/TrEMBL),   A0A8I5ZU56 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955705   ⟸   XM_039099777
- Peptide Label: isoform X3
- UniProtKB: D3ZAW6 (UniProtKB/TrEMBL),   A0A8I5ZU56 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955707   ⟸   XM_039099779
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038955706   ⟸   XM_039099778
- Peptide Label: isoform X4
RefSeq Acc Id: ENSRNOP00000080433   ⟸   ENSRNOT00000100614
RefSeq Acc Id: ENSRNOP00000080987   ⟸   ENSRNOT00000104339
Protein Domains
bHLH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZAW6-F1-model_v2 AlphaFold D3ZAW6 1-573 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1559642 AgrOrtholog
BioCyc Gene G2FUF-2921 BioCyc
Ensembl Genes ENSRNOG00000009605 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000012829 ENTREZGENE
  ENSRNOT00000012829.7 UniProtKB/TrEMBL
  ENSRNOT00000100614 ENTREZGENE
  ENSRNOT00000100614.1 UniProtKB/TrEMBL
  ENSRNOT00000104339.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/TrEMBL
InterPro bHLH_ZIP_TF_MiT/TFE UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/TrEMBL
  HLH_dom UniProtKB/TrEMBL
  MiT/TFE_N UniProtKB/TrEMBL
  TFE3 UniProtKB/TrEMBL
KEGG Report rno:317376 UniProtKB/TrEMBL
NCBI Gene 317376 ENTREZGENE
PANTHER MIP04163P UniProtKB/TrEMBL
  PTHR45776:SF3 UniProtKB/TrEMBL
Pfam DUF3371 UniProtKB/TrEMBL
  HLH UniProtKB/TrEMBL
  MITF_TFEB_C_3_N UniProtKB/TrEMBL
PhenoGen Tfe3 PhenoGen
PROSITE HLH UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009605 RatGTEx
SMART HLH UniProtKB/TrEMBL
Superfamily-SCOP HLH_basic UniProtKB/TrEMBL
UniProt A0A8I5ZPP5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZU56 ENTREZGENE, UniProtKB/TrEMBL
  D3ZAW6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Tcfe3  transcription factor E3   Tcfe3_predicted  transcription factor E3 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Tcfe3_predicted  transcription factor E3 (predicted)  RGD1559642_predicted  similar to Tcfe3 protein (predicted)  Symbol and Name updated 1299863 APPROVED
2006-03-07 RGD1559642_predicted  similar to Tcfe3 protein (predicted)  LOC317376  similar to Tcfe3 protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC317376  similar to Tcfe3 protein      Symbol and Name status set to provisional 70820 PROVISIONAL