Wnk3 (WNK lysine deficient protein kinase 3) - Rat Genome Database

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Gene: Wnk3 (WNK lysine deficient protein kinase 3) Rattus norvegicus
Analyze
Symbol: Wnk3
Name: WNK lysine deficient protein kinase 3
RGD ID: 1563131
Description: Predicted to enable molecular condensate scaffold activity; potassium channel inhibitor activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including negative regulation of pancreatic juice secretion; regulation of metal ion transport; and regulation of protein localization to plasma membrane. Predicted to act upstream of or within maintenance of blood-brain barrier. Predicted to be located in adherens junction and bicellular tight junction. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in Prieto syndrome. Orthologous to human WNK3 (WNK lysine deficient protein kinase 3); INTERACTS WITH 17alpha-ethynylestradiol; 2-methoxyethanol; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC317420; RGD1563131; serine/threonine-protein kinase WNK3; similar to Serine/threonine-protein kinase WNK3 (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3); similar to Serine/threonine-protein kinase WNK3 (Protein kinase, lysine-deficient 3)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X23,599,278 - 23,742,290 (+)NCBIGRCr8
mRatBN7.2X20,156,260 - 20,299,252 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX20,157,041 - 20,296,821 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX17,629,430 - 17,732,398 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X22,391,187 - 22,494,148 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X20,720,518 - 20,823,415 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X20,316,081 - 20,459,245 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX20,316,893 - 20,454,357 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X21,060,886 - 21,204,035 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X40,531,972 - 40,635,583 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX20,447,903 - 20,550,458 (+)NCBICelera
Cytogenetic MapXq12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
adherens junction  (IEA,ISO)
bicellular tight junction  (IEA,ISO)
cytoplasm  (IBA,IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15632090   PMID:16275913   PMID:16501604   PMID:17673510   PMID:17975670   PMID:18768590   PMID:21317537   PMID:21613606   PMID:23482566   PMID:27782176   PMID:32589890   PMID:34626749  


Genomics

Comparative Map Data
Wnk3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X23,599,278 - 23,742,290 (+)NCBIGRCr8
mRatBN7.2X20,156,260 - 20,299,252 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX20,157,041 - 20,296,821 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX17,629,430 - 17,732,398 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X22,391,187 - 22,494,148 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X20,720,518 - 20,823,415 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X20,316,081 - 20,459,245 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX20,316,893 - 20,454,357 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X21,060,886 - 21,204,035 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X40,531,972 - 40,635,583 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX20,447,903 - 20,550,458 (+)NCBICelera
Cytogenetic MapXq12NCBI
WNK3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X54,192,823 - 54,358,900 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX54,192,823 - 54,358,642 (-)EnsemblGRCh38hg38GRCh38
GRCh37X54,219,256 - 54,384,479 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X54,239,580 - 54,401,163 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X54,105,875 - 54,267,459NCBI
CeleraX58,050,484 - 58,215,673 (-)NCBICelera
Cytogenetic MapXp11.22NCBI
HuRefX51,270,978 - 51,435,935 (-)NCBIHuRef
CHM1_1X54,209,950 - 54,375,102 (-)NCBICHM1_1
T2T-CHM13v2.0X53,482,708 - 53,648,791 (-)NCBIT2T-CHM13v2.0
Wnk3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X149,951,774 - 150,103,190 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX149,981,074 - 150,103,148 (+)EnsemblGRCm39 Ensembl
GRCm38X151,168,777 - 151,320,194 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX151,198,078 - 151,320,152 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X147,632,683 - 147,754,695 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X146,538,856 - 146,660,908 (+)NCBIMGSCv36mm8
CeleraX133,089,421 - 133,204,703 (-)NCBICelera
Cytogenetic MapXF3NCBI
cM MapX68.46NCBI
Wnk3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554751,446,498 - 1,642,061 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554751,441,068 - 1,641,599 (-)NCBIChiLan1.0ChiLan1.0
WNK3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X55,576,274 - 55,740,603 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X55,580,716 - 55,744,194 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X46,391,870 - 46,555,232 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X54,629,583 - 54,789,185 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX54,629,583 - 54,789,185 (-)Ensemblpanpan1.1panPan2
WNK3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X45,951,049 - 46,111,643 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX45,571,840 - 46,081,994 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX37,410,899 - 37,499,944 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X46,278,707 - 46,332,213 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1X45,770,039 - 45,930,806 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X46,220,590 - 46,381,230 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X46,287,717 - 46,448,493 (-)NCBIUU_Cfam_GSD_1.0
Wnk3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X38,755,261 - 38,927,032 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367511,100,192 - 1,266,740 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367511,095,578 - 1,266,772 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WNK3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX46,930,184 - 47,096,022 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X46,923,587 - 47,096,265 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X52,773,667 - 52,939,547 (-)NCBISscrofa10.2Sscrofa10.2susScr3
WNK3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X50,320,585 - 50,452,911 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX50,320,674 - 50,452,943 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660864,266,929 - 4,437,306 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wnk3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249091,891,486 - 2,081,735 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249091,886,372 - 2,107,582 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Wnk3
379 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:158
Count of miRNA genes:121
Interacting mature miRNAs:129
Transcripts:ENSRNOT00000047444
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70165Bp64Blood pressure QTL 645.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X144812931706553Rat
1298071Edpm12Estrogen-dependent pituitary mass QTL 123.2pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)X292789847927898Rat
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X143491017Rat
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
10755455Coatc13Coat color QTL 130coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7440600049406000Rat
631666Iddm5Insulin dependent diabetes mellitus QTL 5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X449454949494549Rat
634325Bw13Body weight QTL 130body mass (VT:0001259)body weight (CMO:0000012)X144797220991088Rat
631204Gluco15Glucose level QTL 150.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)X162371522646544Rat
71116Niddm16Non-insulin dependent diabetes mellitus QTL 167.81blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X1529780260297802Rat

Markers in Region
MARC_6238-6239:992007182:3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21124,344,833 - 124,345,305 (+)MAPPERmRatBN7.2
mRatBN7.2X20,199,218 - 20,199,690 (+)MAPPERmRatBN7.2
Rnor_6.01131,793,744 - 131,794,215NCBIRnor6.0
Rnor_6.0X20,359,501 - 20,359,972NCBIRnor6.0
Rnor_5.01132,833,109 - 132,833,580UniSTSRnor5.0
Rnor_5.0X21,104,291 - 21,104,762UniSTSRnor5.0
RGSC_v3.4X40,539,926 - 40,540,397UniSTSRGSC3.4
RGSC_v3.41125,654,803 - 125,655,274UniSTSRGSC3.4
Celera1116,506,905 - 116,507,376UniSTS
CeleraX20,455,858 - 20,456,329UniSTS
Cytogenetic Map1q31UniSTS
Cytogenetic MapXq21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
7 9 44 113 67 66 35 23 35 6 182 88 93 44 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000047444   ⟹   ENSRNOP00000042493
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX20,157,149 - 20,296,821 (+)Ensembl
Rnor_6.0 EnsemblX20,351,548 - 20,454,159 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000082177   ⟹   ENSRNOP00000072423
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX20,157,041 - 20,296,821 (+)Ensembl
Rnor_6.0 EnsemblX20,316,893 - 20,454,357 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093162   ⟹   ENSRNOP00000076217
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX20,423,401 - 20,454,217 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093675   ⟹   ENSRNOP00000076151
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX20,157,149 - 20,296,821 (+)Ensembl
Rnor_6.0 EnsemblX20,351,486 - 20,422,983 (+)Ensembl
RefSeq Acc Id: NM_001163607   ⟹   NP_001157079
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X23,634,308 - 23,737,204 (+)NCBI
mRatBN7.2X20,191,265 - 20,294,166 (+)NCBI
Rnor_6.0X20,351,548 - 20,454,159 (+)NCBI
Rnor_5.0X21,060,886 - 21,204,035 (+)NCBI
RGSC_v3.4X40,531,972 - 40,635,583 (+)RGD
CeleraX20,447,903 - 20,550,458 (+)RGD
Sequence:
RefSeq Acc Id: NM_001411818   ⟹   NP_001398747
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X23,599,305 - 23,742,290 (+)NCBI
mRatBN7.2X20,156,260 - 20,299,252 (+)NCBI
RefSeq Acc Id: XM_006256783   ⟹   XP_006256845
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X23,599,798 - 23,742,290 (+)NCBI
mRatBN7.2X20,156,939 - 20,299,252 (+)NCBI
Rnor_6.0X20,316,779 - 20,459,245 (+)NCBI
Rnor_5.0X21,060,886 - 21,204,035 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008773116   ⟹   XP_008771338
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X23,599,789 - 23,742,290 (+)NCBI
mRatBN7.2X20,156,938 - 20,299,252 (+)NCBI
Rnor_6.0X20,316,779 - 20,459,245 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008773117   ⟹   XP_008771339
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X23,599,805 - 23,742,290 (+)NCBI
mRatBN7.2X20,156,940 - 20,299,252 (+)NCBI
Rnor_6.0X20,316,779 - 20,459,245 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008773118   ⟹   XP_008771340
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X23,599,800 - 23,742,290 (+)NCBI
mRatBN7.2X20,156,939 - 20,299,252 (+)NCBI
Rnor_6.0X20,316,779 - 20,459,245 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017602071   ⟹   XP_017457560
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X23,599,791 - 23,742,290 (+)NCBI
mRatBN7.2X20,156,938 - 20,299,252 (+)NCBI
Rnor_6.0X20,316,779 - 20,459,245 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039099805   ⟹   XP_038955733
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X23,599,985 - 23,742,290 (+)NCBI
mRatBN7.2X20,156,939 - 20,299,252 (+)NCBI
RefSeq Acc Id: XM_039099806   ⟹   XP_038955734
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X23,599,310 - 23,742,290 (+)NCBI
mRatBN7.2X20,156,260 - 20,299,252 (+)NCBI
RefSeq Acc Id: XM_063280058   ⟹   XP_063136128
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X23,599,278 - 23,742,290 (+)NCBI
RefSeq Acc Id: XM_063280059   ⟹   XP_063136129
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X23,599,802 - 23,742,290 (+)NCBI
RefSeq Acc Id: NP_001157079   ⟸   NM_001163607
- Peptide Label: isoform 2
- UniProtKB: D4A7Z8 (UniProtKB/TrEMBL),   A6KLA2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256845   ⟸   XM_006256783
- Peptide Label: isoform X1
- UniProtKB: A0A1W2Q671 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008771338   ⟸   XM_008773116
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008771339   ⟸   XM_008773117
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_008771340   ⟸   XM_008773118
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017457560   ⟸   XM_017602071
- Peptide Label: isoform X3
- Sequence:
Ensembl Acc Id: ENSRNOP00000072423   ⟸   ENSRNOT00000082177
Ensembl Acc Id: ENSRNOP00000042493   ⟸   ENSRNOT00000047444
Ensembl Acc Id: ENSRNOP00000076151   ⟸   ENSRNOT00000093675
Ensembl Acc Id: ENSRNOP00000076217   ⟸   ENSRNOT00000093162
RefSeq Acc Id: XP_038955734   ⟸   XM_039099806
- Peptide Label: isoform X1
- UniProtKB: A0A1W2Q671 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955733   ⟸   XM_039099805
- Peptide Label: isoform X1
- UniProtKB: A0A1W2Q671 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001398747   ⟸   NM_001411818
- Peptide Label: isoform 1
- UniProtKB: A0A1W2Q671 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136128   ⟸   XM_063280058
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063136129   ⟸   XM_063280059
- Peptide Label: isoform X6
- UniProtKB: A0A0G2K2Y2 (UniProtKB/TrEMBL)
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K2Y2-F1-model_v2 AlphaFold A0A0G2K2Y2 1-1698 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701766
Promoter ID:EPDNEW_R12289
Type:multiple initiation site
Name:Wnk3_1
Description:WNK lysine deficient protein kinase 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X20,316,814 - 20,316,874EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563131 AgrOrtholog
BioCyc Gene G2FUF-2776 BioCyc
Ensembl Genes ENSRNOG00000002537 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000047444 ENTREZGENE
  ENSRNOT00000047444.4 UniProtKB/TrEMBL
  ENSRNOT00000082177 ENTREZGENE
  ENSRNOT00000082177.2 UniProtKB/TrEMBL
  ENSRNOT00000093675 ENTREZGENE
  ENSRNOT00000093675.2 UniProtKB/TrEMBL
Gene3D-CATH Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/TrEMBL
  Phosphorylase Kinase, domain 1 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom UniProtKB/TrEMBL
  Kinase_OSR1/WNK_CCT UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
  WNK_Ser-Thr_kinase UniProtKB/TrEMBL
NCBI Gene 317420 ENTREZGENE
PANTHER SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED UniProtKB/TrEMBL
Pfam OSR1_C UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
PhenoGen Wnk3 PhenoGen
PROSITE PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
RatGTEx ENSRNOG00000002537 RatGTEx
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/TrEMBL
UniProt A0A0G2K2Y2 ENTREZGENE, UniProtKB/TrEMBL
  A0A1W2Q671 ENTREZGENE, UniProtKB/TrEMBL
  A6KLA2 ENTREZGENE, UniProtKB/TrEMBL
  D4A7Z8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-11-12 Wnk3  WNK lysine deficient protein kinase 3  RGD1563131  similar to Serine/threonine-protein kinase WNK3 (Protein kinase, lysine-deficient 3)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1563131  similar to Serine/threonine-protein kinase WNK3 (Protein kinase, lysine-deficient 3)   RGD1563131_predicted  similar to Serine/threonine-protein kinase WNK3 (Protein kinase, lysine-deficient 3) (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-10 RGD1563131_predicted  similar to Serine/threonine-protein kinase WNK3 (Protein kinase, lysine-deficient 3) (predicted)    similar to Serine/threonine-protein kinase WNK3 (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3) (predicted)  Name updated 1299863 APPROVED
2006-03-07 RGD1563131_predicted  similar to Serine/threonine-protein kinase WNK3 (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3) (predicted)  LOC317420  similar to Serine/threonine-protein kinase WNK3 (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3)  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC317420  similar to Serine/threonine-protein kinase WNK3 (Protein kinase with no lysine 3) (Protein kinase, lysine-deficient 3)      Symbol and Name status set to provisional 70820 PROVISIONAL