Ctps2 (CTP synthase 2) - Rat Genome Database
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Gene: Ctps2 (CTP synthase 2) Rattus norvegicus
Analyze
Symbol: Ctps2
Name: CTP synthase 2
RGD ID: 1563369
Description: Predicted to have identical protein binding activity. Predicted to be involved in 'de novo' CTP biosynthetic process and glutamine metabolic process. Orthologous to human CTPS2 (CTP synthase 2); PARTICIPATES IN de novo pyrimidine biosynthetic pathway; pyrimidine metabolic pathway; INTERACTS WITH 3,3',5,5'-tetrabromobisphenol A; acrylamide; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CTP synthase II; CTP synthetase 2; cytidine 5'-triphosphate synthase 2; cytidine triphosphate synthase II; UTP--ammonia ligase 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X31,645,873 - 31,786,733 (-)NCBI
Rnor_6.0 EnsemblX33,383,087 - 33,522,836 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X33,383,087 - 33,522,852 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X33,730,550 - 33,870,224 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X52,387,522 - 52,541,409 (-)NCBIRGSC3.4rn4RGSC3.4
CeleraX31,959,615 - 32,091,064 (-)NCBICelera
Cytogenetic MapXq14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:10899599   PMID:15489334   PMID:16189514   PMID:18614015   PMID:25416956   PMID:31515488   PMID:31873303  


Genomics

Comparative Map Data
Ctps2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X31,645,873 - 31,786,733 (-)NCBI
Rnor_6.0 EnsemblX33,383,087 - 33,522,836 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X33,383,087 - 33,522,852 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X33,730,550 - 33,870,224 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X52,387,522 - 52,541,409 (-)NCBIRGSC3.4rn4RGSC3.4
CeleraX31,959,615 - 32,091,064 (-)NCBICelera
Cytogenetic MapXq14NCBI
CTPS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX16,587,999 - 16,712,936 (-)EnsemblGRCh38hg38GRCh38
GRCh38X16,587,999 - 16,712,917 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X16,606,122 - 16,731,033 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X16,516,043 - 16,640,980 (-)NCBINCBI36hg18NCBI36
CeleraX20,724,510 - 20,849,457 (-)NCBI
Cytogenetic MapXp22.2NCBI
HuRefX14,360,950 - 14,485,310 (-)NCBIHuRef
CHM1_1X16,636,520 - 16,761,530 (-)NCBICHM1_1
Ctps2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X161,684,264 - 161,817,537 (+)NCBIGRCm39mm39
GRCm39 EnsemblX161,684,234 - 161,815,504 (+)Ensembl
GRCm38X162,901,268 - 163,034,541 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX162,901,238 - 163,032,508 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X159,339,492 - 159,472,473 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X158,245,710 - 158,376,424 (+)NCBImm8
MGSCv36X140,027,769 - 140,160,968 (+)NCBImm8
CeleraX146,125,743 - 146,259,238 (+)NCBICelera
Cytogenetic MapXF4NCBI
Ctps2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555191,588,182 - 1,647,958 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555191,587,998 - 1,647,810 (+)NCBIChiLan1.0ChiLan1.0
CTPS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X16,579,409 - 16,699,793 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX16,579,409 - 16,693,184 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X9,209,727 - 9,332,641 (-)NCBIMhudiblu_PPA_v0panPan3
CTPS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 EnsemblX12,760,015 - 12,865,111 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1X12,759,998 - 12,867,707 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Ctps2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049364705,889,393 - 5,988,558 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CTPS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX13,049,941 - 13,174,568 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X13,050,740 - 13,181,131 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X13,996,225 - 14,092,759 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CTPS2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X15,027,539 - 15,143,812 (-)NCBI
ChlSab1.1 EnsemblX15,025,876 - 15,143,615 (-)Ensembl
Ctps2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248291,373,568 - 1,438,052 (-)NCBI

Position Markers
DXWox7  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0X33,443,850 - 33,444,060NCBIRnor6.0
Rnor_5.0X33,791,313 - 33,791,523UniSTSRnor5.0
RGSC_v3.4X52,447,480 - 52,447,693RGDRGSC3.4
RGSC_v3.4X52,447,481 - 52,447,693UniSTSRGSC3.4
RGSC_v3.1X52,500,949 - 52,501,162RGD
CeleraX32,020,450 - 32,020,652UniSTS
RH 3.4 MapX451.3UniSTS
RH 3.4 MapX451.3RGD
RH 2.0 Map21345.6RGD
Cytogenetic MapXq21UniSTS
DXMgh12  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0X33,443,848 - 33,444,058NCBIRnor6.0
Rnor_5.0X33,791,311 - 33,791,521UniSTSRnor5.0
RGSC_v3.4X52,447,478 - 52,447,691RGDRGSC3.4
RGSC_v3.4X52,447,479 - 52,447,691UniSTSRGSC3.4
RGSC_v3.1X52,500,947 - 52,501,160RGD
CeleraX32,020,448 - 32,020,650UniSTS
RH 3.4 MapX443.0RGD
RH 3.4 MapX443.0UniSTS
RH 2.0 Map21334.2RGD
Cytogenetic MapXq21UniSTS
DXWox15  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0X33,443,848 - 33,444,058NCBIRnor6.0
Rnor_5.0X33,791,311 - 33,791,521UniSTSRnor5.0
RGSC_v3.4X52,447,478 - 52,447,691RGDRGSC3.4
RGSC_v3.4X52,447,479 - 52,447,691UniSTSRGSC3.4
RGSC_v3.1X52,500,947 - 52,501,160RGD
CeleraX32,020,448 - 32,020,650UniSTS
RH 3.4 MapX451.3RGD
RH 3.4 MapX451.3UniSTS
RH 2.0 Map21340.6RGD
Cytogenetic MapXq21UniSTS
DXWox38  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0X33,443,856 - 33,444,072NCBIRnor6.0
Rnor_5.0X33,791,319 - 33,791,535UniSTSRnor5.0
RGSC_v3.4X52,447,487 - 52,447,705UniSTSRGSC3.4
CeleraX32,020,456 - 32,020,664UniSTS
Cytogenetic MapXq21UniSTS
RH131066  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0X33,384,388 - 33,385,799NCBIRnor6.0
Rnor_5.0X33,731,851 - 33,733,262UniSTSRnor5.0
RGSC_v3.4X52,387,650 - 52,389,061UniSTSRGSC3.4
CeleraX31,960,916 - 31,962,327UniSTS
RH 3.4 MapX456.6UniSTS
Cytogenetic MapXq21UniSTS
RH128976  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0X33,383,144 - 33,383,353NCBIRnor6.0
Rnor_5.0X33,730,607 - 33,730,816UniSTSRnor5.0
RGSC_v3.4X52,386,406 - 52,386,615UniSTSRGSC3.4
CeleraX31,959,672 - 31,959,881UniSTS
RH 3.4 MapX456.1UniSTS
Cytogenetic MapXq21UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X144092703Rat
70165Bp64Blood pressure QTL 645.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X166260933443848Rat
1298071Edpm12Estrogen-dependent pituitary mass QTL 123.2pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)X428214049282140Rat
631666Iddm5Insulin dependent diabetes mellitus QTL 5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X595407850954078Rat
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X15688119127888215Rat
71116Niddm16Non-insulin dependent diabetes mellitus QTL 167.81blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X1815335263153352Rat
1598873Memor2Memory QTL 22.5exploratory behavior trait (VT:0010471)average horizontal distance in proximity to the target during voluntary locomotion in an experimental apparatus (CMO:0002674)X2159262344320739Rat
2290375Gluco34Glucose level QTL 342.75blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)X2159262344468300Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:31
Count of miRNA genes:28
Interacting mature miRNAs:29
Transcripts:ENSRNOT00000059031
Prediction methods:Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 22 53 37 19 37 1 1 74 35 41 11 1
Low 21 4 4 4 7 10 7
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000059031   ⟹   ENSRNOP00000055810
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX33,383,087 - 33,522,836 (-)Ensembl
RefSeq Acc Id: NM_001034998   ⟹   NP_001030170
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X31,645,873 - 31,786,733 (-)NCBI
Rnor_6.0X33,383,087 - 33,522,836 (-)NCBI
Rnor_5.0X33,730,550 - 33,870,224 (-)NCBI
RGSC_v3.4X52,387,522 - 52,541,409 (-)RGD
CeleraX31,959,615 - 32,091,064 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006256896   ⟹   XP_006256958
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X31,645,873 - 31,780,262 (-)NCBI
Rnor_6.0X33,383,087 - 33,516,372 (-)NCBI
Rnor_5.0X33,730,550 - 33,870,224 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006256897   ⟹   XP_006256959
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X31,645,873 - 31,780,259 (-)NCBI
Rnor_6.0X33,383,087 - 33,516,373 (-)NCBI
Rnor_5.0X33,730,550 - 33,870,224 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006256898   ⟹   XP_006256960
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X31,645,873 - 31,780,273 (-)NCBI
Rnor_6.0X33,383,087 - 33,516,373 (-)NCBI
Rnor_5.0X33,730,550 - 33,870,224 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006256899   ⟹   XP_006256961
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X31,645,873 - 31,779,657 (-)NCBI
Rnor_6.0X33,383,087 - 33,515,804 (-)NCBI
Rnor_5.0X33,730,550 - 33,870,224 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006256900   ⟹   XP_006256962
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X31,645,873 - 31,780,583 (-)NCBI
Rnor_6.0X33,383,087 - 33,516,682 (-)NCBI
Rnor_5.0X33,730,550 - 33,870,224 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017602145   ⟹   XP_017457634
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X33,383,087 - 33,522,852 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001030170   ⟸   NM_001034998
- UniProtKB: Q5U2N0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006256962   ⟸   XM_006256900
- Peptide Label: isoform X1
- UniProtKB: Q5U2N0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006256960   ⟸   XM_006256898
- Peptide Label: isoform X1
- UniProtKB: Q5U2N0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006256959   ⟸   XM_006256897
- Peptide Label: isoform X1
- UniProtKB: Q5U2N0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006256958   ⟸   XM_006256896
- Peptide Label: isoform X1
- UniProtKB: Q5U2N0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006256961   ⟸   XM_006256899
- Peptide Label: isoform X1
- UniProtKB: Q5U2N0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017457634   ⟸   XM_017602145
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000055810   ⟸   ENSRNOT00000059031
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563369 AgrOrtholog
Ensembl Genes ENSRNOG00000004257 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000055810 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000059031 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.880 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7132135 IMAGE-MGC_LOAD
  IMAGE:7300883 IMAGE-MGC_LOAD
InterPro Class_I_gatase-like UniProtKB/Swiss-Prot
  CTP_synthase UniProtKB/Swiss-Prot
  CTP_synthase_N UniProtKB/Swiss-Prot
  GATASE UniProtKB/Swiss-Prot
  GATase1_CTP_Synthase UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
KEGG Report rno:619580 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105920 IMAGE-MGC_LOAD
  MGC:95203 IMAGE-MGC_LOAD
NCBI Gene 619580 ENTREZGENE
PANTHER PTHR11550 UniProtKB/Swiss-Prot
Pfam CTP_synth_N UniProtKB/Swiss-Prot
  GATase UniProtKB/Swiss-Prot
PhenoGen Ctps2 PhenoGen
PROSITE GATASE_TYPE_1 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52317 UniProtKB/Swiss-Prot
  SSF52540 UniProtKB/Swiss-Prot
TIGRFAMs PyrG UniProtKB/Swiss-Prot
UniProt PYRG2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q5U3X4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-07-16 Ctps2  CTP synthase 2  Ctps2  CTP synthase II  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-26 Ctps2  CTP synthase II  Ctps2  cytidine 5'-triphosphate synthase 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-03 Ctps2  cytidine 5'-triphosphate synthase 2  Ctps2  cytidine triphosphate synthase II  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 Ctps2  cytidine triphosphate synthase II      Symbol and Name status set to provisional 70820 PROVISIONAL