Ctps2 (CTP synthase 2) - Rat Genome Database

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Gene: Ctps2 (CTP synthase 2) Rattus norvegicus
Analyze
Symbol: Ctps2
Name: CTP synthase 2
RGD ID: 1563369
Description: Predicted to enable CTP synthase activity and identical protein binding activity. Predicted to be involved in CTP biosynthetic process and pyrimidine nucleobase biosynthetic process. Predicted to be located in mitochondrion. Predicted to be active in cytoophidium and cytoplasm. Orthologous to human CTPS2 (CTP synthase 2); PARTICIPATES IN de novo pyrimidine biosynthetic pathway; pyrimidine metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CTP synthase II; CTP synthetase 2; cytidine 5'-triphosphate synthase 2; cytidine triphosphate synthase II; UTP--ammonia ligase 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X35,277,658 - 35,418,505 (-)NCBIGRCr8
mRatBN7.2X31,645,873 - 31,786,733 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX31,645,873 - 31,786,733 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX32,680,414 - 32,821,042 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X36,115,648 - 36,256,507 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X32,304,820 - 32,445,434 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X33,383,087 - 33,522,852 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX33,383,087 - 33,522,836 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X33,730,550 - 33,870,224 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X52,387,522 - 52,541,409 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX31,959,615 - 32,091,064 (-)NCBICelera
Cytogenetic MapXq14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methylcholine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bucladesine  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
choline  (ISO)
ciguatoxin CTX1B  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
endosulfan  (EXP)
finasteride  (EXP)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
furan  (EXP)
indometacin  (EXP)
isoprenaline  (ISO)
ivermectin  (ISO)
L-ascorbic acid  (ISO)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
medroxyprogesterone acetate  (ISO)
methapyrilene  (ISO)
methylmercury chloride  (ISO)
N(4)-hydroxycytidine  (ISO)
N-nitrosodiethylamine  (ISO)
nickel atom  (ISO)
oxaliplatin  (EXP)
p-toluidine  (EXP)
paracetamol  (EXP,ISO)
pentachlorophenol  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (EXP,ISO)
potassium chromate  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
thapsigargin  (EXP)
topotecan  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Regulation of human cytidine triphosphate synthetase 2 by phosphorylation. Kassel KM, etal., J Biol Chem. 2010 Oct 29;285(44):33727-36. Epub 2010 Aug 25.
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
8. Low cytosine triphosphate synthase 2 expression renders resistance to 5-fluorouracil in colorectal cancer. Tan WL, etal., Cancer Biol Ther. 2011 Mar 15;11(6):599-608. Epub 2011 Mar 15.
Additional References at PubMed
PMID:10899599   PMID:15489334   PMID:16189514   PMID:18614015   PMID:25416956   PMID:31515488   PMID:31873303   PMID:34800366  


Genomics

Comparative Map Data
Ctps2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X35,277,658 - 35,418,505 (-)NCBIGRCr8
mRatBN7.2X31,645,873 - 31,786,733 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX31,645,873 - 31,786,733 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX32,680,414 - 32,821,042 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X36,115,648 - 36,256,507 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X32,304,820 - 32,445,434 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X33,383,087 - 33,522,852 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX33,383,087 - 33,522,836 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X33,730,550 - 33,870,224 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X52,387,522 - 52,541,409 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX31,959,615 - 32,091,064 (-)NCBICelera
Cytogenetic MapXq14NCBI
CTPS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X16,587,999 - 16,712,910 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX16,587,999 - 16,712,936 (-)EnsemblGRCh38hg38GRCh38
GRCh37X16,606,122 - 16,731,033 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X16,516,043 - 16,640,980 (-)NCBINCBI36Build 36hg18NCBI36
CeleraX20,724,510 - 20,849,457 (-)NCBICelera
Cytogenetic MapXp22.2NCBI
HuRefX14,360,950 - 14,485,310 (-)NCBIHuRef
CHM1_1X16,636,520 - 16,761,487 (-)NCBICHM1_1
T2T-CHM13v2.0X16,170,460 - 16,295,388 (-)NCBIT2T-CHM13v2.0
Ctps2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X161,684,264 - 161,817,537 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX161,684,234 - 161,815,504 (+)EnsemblGRCm39 Ensembl
GRCm38X162,901,268 - 163,034,541 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX162,901,238 - 163,032,508 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X159,339,492 - 159,472,473 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X158,245,710 - 158,376,424 (+)NCBIMGSCv36mm8
MGSCv36X140,027,769 - 140,160,968 (+)NCBIMGSCv36mm8
CeleraX146,125,743 - 146,259,238 (+)NCBICelera
Cytogenetic MapXF4NCBI
cM MapX75.09NCBI
Ctps2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555191,588,182 - 1,647,958 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555191,587,998 - 1,647,810 (+)NCBIChiLan1.0ChiLan1.0
CTPS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X18,384,654 - 18,507,667 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X18,389,580 - 18,511,051 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X9,209,727 - 9,332,641 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X16,579,409 - 16,699,793 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX16,579,409 - 16,693,184 (-)Ensemblpanpan1.1panPan2
CTPS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X12,759,998 - 12,867,707 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX12,760,015 - 12,865,111 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX12,611,446 - 12,718,873 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X12,720,317 - 12,828,614 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX12,720,323 - 12,828,485 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X12,791,408 - 12,898,767 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X12,777,542 - 12,885,193 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X12,909,665 - 12,951,143 (-)NCBIUU_Cfam_GSD_1.0
Ctps2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X5,888,662 - 5,988,561 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364705,888,469 - 5,988,525 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364705,889,393 - 5,988,558 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CTPS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX13,049,941 - 13,174,568 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X13,050,740 - 13,181,131 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X13,996,225 - 14,092,759 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CTPS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X15,027,539 - 15,143,812 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX15,025,876 - 15,143,615 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605616,872,972 - 16,995,868 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ctps2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248291,386,544 - 1,438,052 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248291,373,568 - 1,438,052 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ctps2
761 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:31
Count of miRNA genes:28
Interacting mature miRNAs:29
Transcripts:ENSRNOT00000059031
Prediction methods:Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598873Memor2Memory QTL 22.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)X2099094741052531Rat
70165Bp64Blood pressure QTL 645.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X144812931706553Rat
1298071Edpm12Estrogen-dependent pituitary mass QTL 123.2pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)X292789847927898Rat
2290375Gluco34Glucose level QTL 342.75blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)X2099094741203591Rat
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X143491017Rat
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
10755455Coatc13Coat color QTL 130coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7440600049406000Rat
631666Iddm5Insulin dependent diabetes mellitus QTL 5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X449454949494549Rat
71116Niddm16Non-insulin dependent diabetes mellitus QTL 167.81blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X1529780260297802Rat

Markers in Region
DXWox7  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X31,706,555 - 31,706,768 (+)MAPPERmRatBN7.2
Rnor_6.0X33,443,850 - 33,444,060NCBIRnor6.0
Rnor_5.0X33,791,313 - 33,791,523UniSTSRnor5.0
RGSC_v3.4X52,447,480 - 52,447,693RGDRGSC3.4
RGSC_v3.4X52,447,481 - 52,447,693UniSTSRGSC3.4
RGSC_v3.1X52,500,949 - 52,501,162RGD
CeleraX32,020,450 - 32,020,652UniSTS
RH 3.4 MapX451.3UniSTS
RH 3.4 MapX451.3RGD
RH 2.0 Map21345.6RGD
Cytogenetic MapXq21UniSTS
DXMgh12  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X31,706,553 - 31,706,766 (+)MAPPERmRatBN7.2
Rnor_6.0X33,443,848 - 33,444,058NCBIRnor6.0
Rnor_5.0X33,791,311 - 33,791,521UniSTSRnor5.0
RGSC_v3.4X52,447,478 - 52,447,691RGDRGSC3.4
RGSC_v3.4X52,447,479 - 52,447,691UniSTSRGSC3.4
RGSC_v3.1X52,500,947 - 52,501,160RGD
CeleraX32,020,448 - 32,020,650UniSTS
RH 3.4 MapX443.0UniSTS
RH 3.4 MapX443.0RGD
RH 2.0 Map21334.2RGD
Cytogenetic MapXq21UniSTS
DXWox15  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X31,706,553 - 31,706,766 (+)MAPPERmRatBN7.2
Rnor_6.0X33,443,848 - 33,444,058NCBIRnor6.0
Rnor_5.0X33,791,311 - 33,791,521UniSTSRnor5.0
RGSC_v3.4X52,447,478 - 52,447,691RGDRGSC3.4
RGSC_v3.4X52,447,479 - 52,447,691UniSTSRGSC3.4
RGSC_v3.1X52,500,947 - 52,501,160RGD
CeleraX32,020,448 - 32,020,650UniSTS
RH 3.4 MapX451.3UniSTS
RH 3.4 MapX451.3RGD
RH 2.0 Map21340.6RGD
Cytogenetic MapXq21UniSTS
DXWox38  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X31,706,561 - 31,706,780 (+)MAPPERmRatBN7.2
Rnor_6.0X33,443,856 - 33,444,072NCBIRnor6.0
Rnor_5.0X33,791,319 - 33,791,535UniSTSRnor5.0
RGSC_v3.4X52,447,487 - 52,447,705UniSTSRGSC3.4
CeleraX32,020,456 - 32,020,664UniSTS
Cytogenetic MapXq21UniSTS
RH131066  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X31,647,173 - 31,648,585 (+)MAPPERmRatBN7.2
Rnor_6.0X33,384,388 - 33,385,799NCBIRnor6.0
Rnor_5.0X33,731,851 - 33,733,262UniSTSRnor5.0
RGSC_v3.4X52,387,650 - 52,389,061UniSTSRGSC3.4
CeleraX31,960,916 - 31,962,327UniSTS
RH 3.4 MapX456.6UniSTS
Cytogenetic MapXq21UniSTS
RH128976  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X31,645,929 - 31,646,139 (+)MAPPERmRatBN7.2
Rnor_6.0X33,383,144 - 33,383,353NCBIRnor6.0
Rnor_5.0X33,730,607 - 33,730,816UniSTSRnor5.0
RGSC_v3.4X52,386,406 - 52,386,615UniSTSRGSC3.4
CeleraX31,959,672 - 31,959,881UniSTS
RH 3.4 MapX456.1UniSTS
Cytogenetic MapXq21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000059031   ⟹   ENSRNOP00000055810
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX31,645,873 - 31,786,733 (-)Ensembl
Rnor_6.0 EnsemblX33,383,087 - 33,522,836 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101251   ⟹   ENSRNOP00000083758
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX31,645,873 - 31,786,733 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000102947   ⟹   ENSRNOP00000097478
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX31,647,046 - 31,780,262 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106996   ⟹   ENSRNOP00000084727
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX31,664,598 - 31,780,120 (-)Ensembl
RefSeq Acc Id: NM_001034998   ⟹   NP_001030170
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X35,277,658 - 35,418,505 (-)NCBI
mRatBN7.2X31,645,873 - 31,786,733 (-)NCBI
Rnor_6.0X33,383,087 - 33,522,836 (-)NCBI
Rnor_5.0X33,730,550 - 33,870,224 (-)NCBI
RGSC_v3.4X52,387,522 - 52,541,409 (-)RGD
CeleraX31,959,615 - 32,091,064 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006256896   ⟹   XP_006256958
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X35,277,658 - 35,412,033 (-)NCBI
mRatBN7.2X31,645,873 - 31,780,262 (-)NCBI
Rnor_6.0X33,383,087 - 33,516,372 (-)NCBI
Rnor_5.0X33,730,550 - 33,870,224 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006256897   ⟹   XP_006256959
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X35,277,658 - 35,412,028 (-)NCBI
mRatBN7.2X31,645,873 - 31,780,259 (-)NCBI
Rnor_6.0X33,383,087 - 33,516,373 (-)NCBI
Rnor_5.0X33,730,550 - 33,870,224 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006256898   ⟹   XP_006256960
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X35,277,658 - 35,412,047 (-)NCBI
mRatBN7.2X31,645,873 - 31,780,273 (-)NCBI
Rnor_6.0X33,383,087 - 33,516,373 (-)NCBI
Rnor_5.0X33,730,550 - 33,870,224 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006256899   ⟹   XP_006256961
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X35,277,658 - 35,411,313 (-)NCBI
mRatBN7.2X31,645,873 - 31,779,657 (-)NCBI
Rnor_6.0X33,383,087 - 33,515,804 (-)NCBI
Rnor_5.0X33,730,550 - 33,870,224 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006256900   ⟹   XP_006256962
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X35,277,658 - 35,412,354 (-)NCBI
mRatBN7.2X31,645,873 - 31,780,583 (-)NCBI
Rnor_6.0X33,383,087 - 33,516,682 (-)NCBI
Rnor_5.0X33,730,550 - 33,870,224 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001030170   ⟸   NM_001034998
- UniProtKB: Q5U3X4 (UniProtKB/Swiss-Prot),   Q5U2N0 (UniProtKB/Swiss-Prot),   A0A8L2QRH2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256962   ⟸   XM_006256900
- Peptide Label: isoform X1
- UniProtKB: Q5U3X4 (UniProtKB/Swiss-Prot),   Q5U2N0 (UniProtKB/Swiss-Prot),   A0A8L2QRH2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256960   ⟸   XM_006256898
- Peptide Label: isoform X1
- UniProtKB: Q5U3X4 (UniProtKB/Swiss-Prot),   Q5U2N0 (UniProtKB/Swiss-Prot),   A0A8L2QRH2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256959   ⟸   XM_006256897
- Peptide Label: isoform X1
- UniProtKB: Q5U3X4 (UniProtKB/Swiss-Prot),   Q5U2N0 (UniProtKB/Swiss-Prot),   A0A8L2QRH2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256958   ⟸   XM_006256896
- Peptide Label: isoform X1
- UniProtKB: Q5U3X4 (UniProtKB/Swiss-Prot),   Q5U2N0 (UniProtKB/Swiss-Prot),   A0A8L2QRH2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256961   ⟸   XM_006256899
- Peptide Label: isoform X1
- UniProtKB: Q5U3X4 (UniProtKB/Swiss-Prot),   Q5U2N0 (UniProtKB/Swiss-Prot),   A0A8L2QRH2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000055810   ⟸   ENSRNOT00000059031
Ensembl Acc Id: ENSRNOP00000083758   ⟸   ENSRNOT00000101251
Ensembl Acc Id: ENSRNOP00000084727   ⟸   ENSRNOT00000106996
Ensembl Acc Id: ENSRNOP00000097478   ⟸   ENSRNOT00000102947
Protein Domains
CTP synthase N-terminal   Glutamine amidotransferase   Glutamine amidotransferase type-1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5U2N0-F1-model_v2 AlphaFold Q5U2N0 1-586 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563369 AgrOrtholog
BioCyc Gene G2FUF-2545 BioCyc
BioCyc Pathway CITRULBIO-PWY [L-citrulline biosynthesis] BioCyc
  GLUTAMINDEG-PWY [L-glutamine degradation I] BioCyc
  PWY-5921 [glutaminyl-tRNAgln biosynthesis via transamidation] BioCyc
  PWY-7176 [UTP and CTP de novo biosynthesis] BioCyc
  PWY-7185 [UTP and CTP dephosphorylation I] BioCyc
BioCyc Pathway Image CITRULBIO-PWY BioCyc
  GLUTAMINDEG-PWY BioCyc
  PWY-5921 BioCyc
  PWY-7176 BioCyc
  PWY-7185 BioCyc
Ensembl Genes ENSRNOG00000004257 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000059031.4 UniProtKB/TrEMBL
  ENSRNOT00000101251.1 UniProtKB/TrEMBL
  ENSRNOT00000102947.1 UniProtKB/TrEMBL
  ENSRNOT00000106996.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.880 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7132135 IMAGE-MGC_LOAD
  IMAGE:7300883 IMAGE-MGC_LOAD
InterPro Class_I_gatase-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CTP_synthase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CTP_synthase_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GATASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GATase1_CTP_Synthase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:619580 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105920 IMAGE-MGC_LOAD
  MGC:95203 IMAGE-MGC_LOAD
NCBI Gene 619580 ENTREZGENE
PANTHER CTP SYNTHASE 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11550 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam CTP_synth_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GATase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ctps2 PhenoGen
PROSITE GATASE_TYPE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004257 RatGTEx
Superfamily-SCOP SSF52317 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZX96_RAT UniProtKB/TrEMBL
  A0A8I6A1W6_RAT UniProtKB/TrEMBL
  A0A8I6AWE7_RAT UniProtKB/TrEMBL
  A0A8L2QRH2 ENTREZGENE, UniProtKB/TrEMBL
  A6K2N2_RAT UniProtKB/TrEMBL
  PYRG2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q5U3X4 ENTREZGENE
UniProt Secondary Q5U3X4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-07-16 Ctps2  CTP synthase 2  Ctps2  CTP synthase II  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-26 Ctps2  CTP synthase II  Ctps2  cytidine 5'-triphosphate synthase 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-03 Ctps2  cytidine 5'-triphosphate synthase 2  Ctps2  cytidine triphosphate synthase II  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 Ctps2  cytidine triphosphate synthase II      Symbol and Name status set to provisional 70820 PROVISIONAL