Maoa (monoamine oxidase A) - Rat Genome Database

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Gene: Maoa (monoamine oxidase A) Rattus norvegicus
Analyze
Symbol: Maoa
Name: monoamine oxidase A
RGD ID: 61898
Description: Enables flavin adenine dinucleotide binding activity; oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor; and serotonin binding activity. Involved in phenylethylamine metabolic process and serotonin metabolic process. Located in mitochondrial outer membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease; Brunner Syndrome; alcohol use disorder; autism spectrum disorder; and panic disorder. Orthologous to human MAOA (monoamine oxidase A); PARTICIPATES IN alkaptonuria pathway; citalopram pharmacodynamics pathway; citalopram pharmacokinetics pathway; INTERACTS WITH (5-hydroxyindol-3-yl)acetic acid; 17beta-estradiol; 2-methoxyethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: amine oxidase [flavin-containing] A; Mao; MAO-A; monoamine oxidase; monoamine oxidase type A
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X6,032,172 - 6,098,308 (-)NCBImRatBN7.2
mRatBN7.2 EnsemblX6,030,795 - 6,099,593 (-)Ensembl
Rnor_6.0X6,554,698 - 6,620,722 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX6,554,698 - 6,620,722 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X7,373,101 - 7,439,125 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X17,678,960 - 17,745,908 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X17,731,861 - 17,799,225 (-)NCBI
CeleraX6,522,076 - 6,588,367 (-)NCBICelera
Cytogenetic MapXq11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+-)-Carnegine  (ISO)
(-)-Salsoline  (ISO)
(-)-selegiline  (ISO)
(5-hydroxyindol-3-yl)acetaldehyde  (ISO)
(5-hydroxyindol-3-yl)acetic acid  (EXP)
(R)-noradrenaline  (ISO)
(R)-Salsolinol  (ISO)
(S)-nicotine  (ISO)
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2-methoxyethanol  (EXP)
2-methylcholine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,4-Methylenedioxyamphetamine  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-Amino-1-methyl-5H-pyrido[4,3-b]indole  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-methyl-N'-(phenylmethyl)-3-isoxazolecarbohydrazide  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
almotriptan  (ISO)
alpha-methyltryptamine  (ISO)
alpha-Zearalanol  (ISO)
amitraz  (EXP)
amitriptyline  (EXP)
ammonium acetate  (EXP)
ammonium chloride  (EXP)
amphetamine  (EXP)
antimonite  (ISO)
arecoline  (ISO)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
astemizole  (EXP)
atrazine  (EXP,ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzyl benzoate  (ISO)
benzyl cinnamate  (ISO)
beta-carboline  (ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
cadmium atom  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
captan  (ISO)
carbamazepine  (ISO)
carbidopa  (ISO)
carbon nanotube  (ISO)
chlorogenic acid  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (EXP)
choline  (ISO)
chrysene  (ISO)
cis-caffeic acid  (ISO)
cisplatin  (ISO)
clorgyline  (EXP,ISO)
cobalt dichloride  (EXP)
cocaine  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
cortisol  (ISO)
curcumin  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
cypermethrin  (EXP)
dexamethasone  (EXP,ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dichlorvos  (EXP)
diclofenac  (ISO)
diethyl maleate  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
disulfiram  (ISO)
diuron  (EXP)
dizocilpine maleate  (EXP)
dopamine  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
endosulfan  (ISO)
entinostat  (ISO)
ethanol  (EXP,ISO)
fenvalerate  (EXP)
finasteride  (EXP)
flavanone  (ISO)
flavone  (ISO)
flutamide  (EXP)
folic acid  (ISO)
folpet  (ISO)
fructose  (EXP)
fucoxanthin  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
gentamycin  (EXP)
harmaline  (EXP,ISO)
harman  (ISO)
harmine  (EXP,ISO)
Heliotrine  (ISO)
hydralazine  (ISO)
indol-3-ylacetaldehyde  (ISO)
iron atom  (EXP)
iron(0)  (EXP)
isoflavones  (ISO)
kojic acid  (EXP)
kynuramine  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
lead(II) chloride  (ISO)
linezolid  (ISO)
luteolin  (ISO)
Metanephrine  (ISO)
methamphetamine  (EXP,ISO)
methapyrilene  (EXP)
methotrexate  (ISO)
mifepristone  (ISO)
mithramycin  (ISO)
moclobemide  (EXP,ISO)
monocrotophos  (EXP)
monosodium L-glutamate  (ISO)
N(gamma)-nitro-L-arginine methyl ester  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
naringin  (EXP)
nefazodone  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
nicotine  (ISO)
nitroprusside  (ISO)
ochratoxin A  (EXP)
olanzapine  (EXP)
Paeonol  (EXP)
paracetamol  (EXP,ISO)
parathion-methyl  (EXP)
Pargyline  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (ISO)
phenylephrine  (ISO)
phenylmercury acetate  (ISO)
phenylpropanolamine  (EXP,ISO)
PhIP  (EXP)
phosphamidon  (EXP)
piperine  (EXP,ISO)
pirinixic acid  (EXP,ISO)
procarbazine  (EXP)
progesterone  (ISO)
propanal  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
risperidone  (ISO)
rosmarinic acid  (ISO)
rotenone  (EXP)
sarpogrelate  (ISO)
SB 431542  (ISO)
senecionine  (ISO)
Senkirkine  (ISO)
serotonin  (EXP,ISO)
sertraline  (ISO)
simazine  (EXP,ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
sulindac  (EXP)
tamoxifen  (EXP)
temozolomide  (ISO)
testosterone  (EXP)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thapsigargin  (ISO)
thimerosal  (ISO)
titanium dioxide  (ISO)
toloxatone  (EXP)
toluene  (EXP)
trans-caffeic acid  (ISO)
trichostatin A  (ISO)
troglitazone  (ISO)
tryptamine  (ISO)
tyramine  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)
yohimbine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
1. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA data from the GO Consortium
3. Guindalini C, etal., Psychiatr Genet. 2005 Jun;15(2):141-4.
4. Heron P, etal., Life Sci. 2001 Feb 23;68(14):1575-83.
5. Kuwahara T, etal., Agric Biol Chem 1990 Jan;54(1):253-7.
6. Ma J and Ito A, J Biochem (Tokyo). 2002 Jan;131(1):107-11.
7. Maron E, etal., Int J Neuropsychopharmacol. 2005 Jun;8(2):261-6. Epub 2005 Jan 26.
8. Marziniak M, etal., J Neural Transm. 2004 May;111(5):603-9.
9. MGD data from the GO Consortium
10. NCBI rat LocusLink and RefSeq merged data July 26, 2002
11. O'Carroll AM, etal., Neurochem Int. 1986;8(4):493-500. doi: 10.1016/0197-0186(86)90182-8.
12. OMIM Disease Annotation Pipeline
13. Park Y, etal., J Child Neurol. 2014 Dec;29(12):NP207-11. doi: 10.1177/0883073813511301. Epub 2013 Dec 18.
14. Pipeline to import KEGG annotations from KEGG into RGD
15. Pipeline to import SMPDB annotations from SMPDB into RGD
16. Pizzinat N, etal., Am J Physiol Renal Physiol 2003 Jan;284(1):F167-74.
17. RGD automated data pipeline
18. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
19. RGD automated import pipeline for gene-chemical interactions
20. Sherif F, etal., J Neural Transm Park Dis Dement Sect. 1992;4(3):227-40.
21. Son SY, etal., Proc Natl Acad Sci U S A. 2008 Apr 15;105(15):5739-44. doi: 10.1073/pnas.0710626105. Epub 2008 Apr 7.
22. Tsugeno Y and Ito A, J Biol Chem. 1997 May 30;272(22):14033-6. doi: 10.1074/jbc.272.22.14033.
Additional References at PubMed
PMID:9520487   PMID:12477932   PMID:12531732   PMID:14651853   PMID:14747710   PMID:15050826   PMID:15526171   PMID:16129825   PMID:16286591   PMID:16421512   PMID:16631124   PMID:17158340  
PMID:17561096   PMID:18092818   PMID:18614015   PMID:19456107   PMID:19883764   PMID:19909795   PMID:20833797   PMID:21341713   PMID:21700703   PMID:21819071   PMID:22225631   PMID:22738191  
PMID:22871113   PMID:23321813   PMID:23581564   PMID:23926250   PMID:25315831   PMID:26122707   PMID:26645625   PMID:26689857   PMID:27503749   PMID:28653655   PMID:28857544   PMID:28948423  
PMID:29227084   PMID:29476059   PMID:29549852   PMID:30167938   PMID:33264068   PMID:34244591  


Genomics

Comparative Map Data
Maoa
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X6,032,172 - 6,098,308 (-)NCBImRatBN7.2
mRatBN7.2 EnsemblX6,030,795 - 6,099,593 (-)Ensembl
Rnor_6.0X6,554,698 - 6,620,722 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX6,554,698 - 6,620,722 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X7,373,101 - 7,439,125 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X17,678,960 - 17,745,908 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X17,731,861 - 17,799,225 (-)NCBI
CeleraX6,522,076 - 6,588,367 (-)NCBICelera
Cytogenetic MapXq11NCBI
MAOA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X43,655,006 - 43,746,817 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 EnsemblX43,654,907 - 43,746,817 (+)EnsemblGRCh38hg38GRCh38
GRCh37X43,514,254 - 43,606,064 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X43,400,353 - 43,491,012 (+)NCBINCBI36hg18NCBI36
Build 34X43,271,662 - 43,362,321NCBI
CeleraX47,658,765 - 47,745,839 (+)NCBI
Cytogenetic MapXp11.3NCBI
HuRefX41,244,782 - 41,335,636 (+)NCBIHuRef
CHM1_1X43,547,315 - 43,639,233 (+)NCBICHM1_1
T2T-CHM13v2.0X43,061,181 - 43,153,033 (+)NCBI
Maoa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X16,485,937 - 16,554,051 (+)NCBIGRCm39mm39
GRCm39 EnsemblX16,485,937 - 16,554,057 (+)Ensembl
GRCm38X16,619,698 - 16,687,812 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX16,619,698 - 16,687,818 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X16,196,824 - 16,264,938 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X15,776,657 - 15,844,677 (+)NCBImm8
CeleraX14,235,521 - 14,303,664 (+)NCBICelera
Cytogenetic MapXA1.2NCBI
cM MapX11.78NCBI
Maoa
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555164,493,946 - 4,576,317 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555164,494,133 - 4,576,317 (-)NCBIChiLan1.0ChiLan1.0
MAOA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X43,931,198 - 44,022,199 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX43,931,044 - 44,022,199 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X36,106,680 - 36,197,907 (+)NCBIMhudiblu_PPA_v0panPan3
MAOA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X37,678,933 - 37,744,757 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX37,677,493 - 37,744,757 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX24,906,697 - 24,972,819 (+)NCBI
ROS_Cfam_1.0X37,766,823 - 37,832,990 (+)NCBI
ROS_Cfam_1.0 EnsemblX37,765,383 - 37,835,465 (+)Ensembl
UMICH_Zoey_3.1X37,808,131 - 37,874,259 (+)NCBI
UNSW_CanFamBas_1.0X37,790,918 - 37,857,220 (+)NCBI
UU_Cfam_GSD_1.0X37,886,004 - 37,952,154 (+)NCBI
Maoa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X29,974,871 - 30,047,257 (+)NCBI
SpeTri2.0NW_0049365029,816,443 - 9,888,002 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAOA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1X38,930,452 - 39,006,220 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X43,132,736 - 43,208,694 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MAOA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X40,834,158 - 40,920,404 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 EnsemblX40,834,159 - 40,920,444 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660766,054,881 - 6,139,601 (+)NCBIVero_WHO_p1.0
Maoa
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476211,743,712 - 11,822,377 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462476211,743,833 - 11,820,529 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
DXGot196  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X6,091,260 - 6,091,463 (+)MAPPERmRatBN7.2
Rnor_6.0X6,613,673 - 6,613,875NCBIRnor6.0
Rnor_5.0X7,432,076 - 7,432,278UniSTSRnor5.0
RGSC_v3.4X17,738,859 - 17,739,061UniSTSRGSC3.4
CeleraX6,580,720 - 6,580,922UniSTS
Cytogenetic MapXq12UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X143491017Rat
70166Bp65Blood pressure QTL 655.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X144797211374346Rat
634325Bw13Body weight QTL 130body mass (VT:0001259)body weight (CMO:0000012)X144797220991088Rat
70165Bp64Blood pressure QTL 645.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X144812931706553Rat
631204Gluco15Glucose level QTL 150.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)X162371522646544Rat
1298071Edpm12Estrogen-dependent pituitary mass QTL 123.2pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)X292789847927898Rat
10755455Coatc13Coat color QTL 130coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7440600049406000Rat
631666Iddm5Insulin dependent diabetes mellitus QTL 5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X449454949494549Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:150
Count of miRNA genes:132
Interacting mature miRNAs:139
Transcripts:ENSRNOT00000066674
Prediction methods:Microtar, Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 51 41 13 41 8 10 74 35 38 11 8
Low 6 6 1 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000066674   ⟹   ENSRNOP00000063784
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX6,030,795 - 6,098,317 (-)Ensembl
Rnor_6.0 EnsemblX6,554,698 - 6,620,722 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000097866   ⟹   ENSRNOP00000097595
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX6,030,795 - 6,099,593 (-)Ensembl
RefSeq Acc Id: NM_033653   ⟹   NP_387502
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X6,032,172 - 6,098,308 (-)NCBI
Rnor_6.0X6,554,698 - 6,620,722 (-)NCBI
Rnor_5.0X7,373,101 - 7,439,125 (-)NCBI
RGSC_v3.4X17,678,960 - 17,745,908 (-)RGD
CeleraX6,522,076 - 6,588,367 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_387502 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI66508 (Get FASTA)   NCBI Sequence Viewer  
  BAA00592 (Get FASTA)   NCBI Sequence Viewer  
  EDL97663 (Get FASTA)   NCBI Sequence Viewer  
  P21396 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_387502   ⟸   NM_033653
- UniProtKB: G3V9Z3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000063784   ⟸   ENSRNOT00000066674
RefSeq Acc Id: ENSRNOP00000097595   ⟸   ENSRNOT00000097866
Protein Domains
Amino_oxidase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P21396-F1-model_v2 AlphaFold P21396 1-526 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701705
Promoter ID:EPDNEW_R12228
Type:multiple initiation site
Name:Maoa_1
Description:monoamine oxidase A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X6,620,727 - 6,620,787EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
X 17680796 17680797 C G snv ACI/EurMcwi (MCW), SR/JrHsd (MCW), FHH/EurMcwi (MCW)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61898 AgrOrtholog
BioCyc Gene G2FUF-3112 BioCyc
BioCyc Pathway PWY-0 [putrescine degradation III] BioCyc
  PWY-6307 [L-tryptophan degradation X (mammalian, via tryptamine)] BioCyc
  PWY-6313 [serotonin degradation] BioCyc
  PWY-6318 [L-phenylalanine degradation IV (mammalian, via side chain)] BioCyc
  PWY-6342 [noradrenaline and adrenaline degradation] BioCyc
  PWY-6399 [melatonin degradation II] BioCyc
  PWY6666-2 [dopamine degradation] BioCyc
Ensembl Genes ENSRNOG00000002848 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000063784 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000066674 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.50.50.60 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7127176 IMAGE-MGC_LOAD
InterPro Amino_oxidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FAD/NAD-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Flavin_amine_oxidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29253 UniProtKB/TrEMBL
MGC_CLONE MGC:188076 IMAGE-MGC_LOAD
NCBI Gene 29253 ENTREZGENE
Pfam Amino_oxidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB MAOA RGD
PhenoGen Maoa PhenoGen
PRINTS AMINEOXDASEF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF51905 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt AOFA_RAT UniProtKB/Swiss-Prot
  B2GV33_RAT UniProtKB/TrEMBL
  G3V9Z3 ENTREZGENE, UniProtKB/TrEMBL
  P21396 ENTREZGENE
UniProt Secondary Q63817 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Maoa  monoamine oxidase A       Name updated 70584 APPROVED
2001-06-12 Mao  Monoamine oxidase      Symbol and Name withdrawn 62408 WITHDRAWN

RGD Curation Notes
Note Type Note Reference
gene_protein 526 amino acid residues 61656