1,2-dichloroethane decreases expression ISO RGD:732282 6480464 ethylene dichloride results in decreased expression of ALAS2 mRNA CTD PMID:28189721 , PMID:28960355 17alpha-ethynylestradiol multiple interactions ISO RGD:732282 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ALAS2 mRNA CTD PMID:17942748 17beta-estradiol increases expression ISO RGD:732282 6480464 Estradiol results in increased expression of ALAS2 mRNA CTD PMID:16684588 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:732282 6480464 2 more ... CTD PMID:32352317 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of ALAS2 mRNA CTD PMID:16054898 , PMID:16466705 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:732282 6480464 Tetrachlorodibenzodioxin results in decreased expression of ALAS2 mRNA CTD PMID:28213091 , PMID:29673856 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:732282 6480464 Tetrachlorodibenzodioxin affects the expression of ALAS2 mRNA CTD PMID:28922406 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of ALAS2 mRNA CTD PMID:21215274 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:732282 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ALAS2 mRNA CTD PMID:17942748 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of ALAS2 mRNA CTD PMID:21346803 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3 more ... CTD PMID:20959002 3H-1,2-dithiole-3-thione decreases expression ISO RGD:732282 6480464 1, 2-dithiol-3-thione results in decreased expression of ALAS2 mRNA CTD PMID:15302862 3H-1,2-dithiole-3-thione decreases expression EXP 6480464 1, 2-dithiol-3-thione results in decreased expression of ALAS2 mRNA CTD PMID:19162173 4,4'-sulfonyldiphenol increases expression ISO RGD:732282 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of ALAS2 mRNA CTD PMID:30951980 4-hydroxyphenyl retinamide decreases expression ISO RGD:732282 6480464 Fenretinide results in decreased expression of ALAS2 mRNA CTD PMID:28973697 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of ALAS2 mRNA CTD PMID:24780913 , PMID:25825206 7,12-dimethyltetraphene increases expression EXP 6480464 9 more ... CTD PMID:19480007 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of ALAS2 mRNA CTD PMID:31881176 aflatoxin B1 decreases methylation ISO RGD:736755 6480464 Aflatoxin B1 results in decreased methylation of ALAS2 gene CTD PMID:27153756 amiodarone decreases expression ISO RGD:732282 6480464 Amiodarone results in decreased expression of ALAS2 mRNA CTD PMID:24535564 antirheumatic drug decreases expression ISO RGD:736755 6480464 Antirheumatic Agents results in decreased expression of ALAS2 mRNA CTD PMID:24449571 arsenous acid increases expression ISO RGD:736755 6480464 Arsenic Trioxide results in increased expression of ALAS2 mRNA CTD PMID:20458559 astemizole increases expression EXP 6480464 Astemizole results in increased expression of ALAS2 mRNA CTD PMID:20221588 benzene decreases expression ISO RGD:732282 6480464 Benzene results in decreased expression of ALAS2 mRNA CTD PMID:15120971 , PMID:15122651 benzene affects expression EXP 6480464 Benzene affects the expression of ALAS2 mRNA CTD PMID:15878777 benzo[a]pyrene decreases expression ISO RGD:732282 6480464 Benzo(a)pyrene results in decreased expression of ALAS2 mRNA CTD PMID:21569818 , PMID:27195522 benzo[a]pyrene decreases methylation ISO RGD:736755 6480464 Benzo(a)pyrene results in decreased methylation of ALAS2 5' UTR CTD PMID:27901495 benzo[a]pyrene increases methylation ISO RGD:736755 6480464 Benzo(a)pyrene results in increased methylation of ALAS2 promoter CTD PMID:27901495 benzo[b]fluoranthene decreases expression ISO RGD:732282 6480464 benzo(b)fluoranthene results in decreased expression of ALAS2 mRNA CTD PMID:26377693 beta-naphthoflavone multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ALAS2 mRNA CTD PMID:18164116 bisphenol A decreases expression ISO RGD:732282 6480464 bisphenol A results in decreased expression of ALAS2 mRNA CTD PMID:26063408 bisphenol A decreases methylation ISO RGD:736755 6480464 bisphenol A results in decreased methylation of ALAS2 gene CTD PMID:31601247 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of ALAS2 mRNA CTD PMID:30816183 more ... bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of ALAS2 mRNA CTD PMID:25181051 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of ALAS2 mRNA CTD PMID:25993096 carbamazepine affects expression ISO RGD:736755 6480464 Carbamazepine affects the expression of ALAS2 mRNA CTD PMID:24752500 carbon nanotube decreases expression ISO RGD:732282 6480464 Nanotubes, Carbon results in decreased expression of ALAS2 mRNA CTD PMID:25554681 carbonyl sulfide decreases expression EXP 6480464 carbonyl sulfide results in decreased expression of ALAS2 mRNA CTD PMID:19395590 carboplatin decreases expression EXP 6480464 Carboplatin results in decreased expression of ALAS2 mRNA CTD PMID:21296123 carmustine decreases expression EXP 6480464 Carmustine results in decreased expression of ALAS2 mRNA CTD PMID:16005536 catechol increases expression ISO RGD:736755 6480464 catechol results in increased expression of ALAS2 mRNA CTD PMID:23022512 , PMID:28552822 catechol multiple interactions ISO RGD:736755 6480464 [catechol co-treated with Hemin] results in increased expression of ALAS2 mRNA more ... CTD PMID:24141029 , PMID:28552822 chloroprene decreases expression EXP 6480464 Chloroprene results in decreased expression of ALAS2 mRNA CTD PMID:23125180 cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of ALAS2 mRNA CTD PMID:21296123 clofibrate multiple interactions ISO RGD:732282 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of ALAS2 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of ALAS2 mRNA] CTD PMID:17585979 copper atom multiple interactions EXP 6480464 [Copper co-treated with Dietary Sucrose] results in increased expression of ALAS2 mRNA CTD PMID:26033743 copper atom increases expression ISO RGD:732282 6480464 Copper results in increased expression of ALAS2 mRNA CTD PMID:17205981 copper atom increases expression EXP 6480464 Copper deficiency results in increased expression of ALAS2 mRNA CTD PMID:26033743 copper(0) multiple interactions EXP 6480464 [Copper co-treated with Dietary Sucrose] results in increased expression of ALAS2 mRNA CTD PMID:26033743 copper(0) increases expression ISO RGD:732282 6480464 Copper results in increased expression of ALAS2 mRNA CTD PMID:17205981 copper(0) increases expression EXP 6480464 Copper deficiency results in increased expression of ALAS2 mRNA CTD PMID:26033743 crocidolite asbestos decreases expression ISO RGD:732282 6480464 Asbestos, Crocidolite results in decreased expression of ALAS2 mRNA CTD PMID:29279043 Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of ALAS2 mRNA CTD PMID:26577399 diarsenic trioxide increases expression ISO RGD:736755 6480464 Arsenic Trioxide results in increased expression of ALAS2 mRNA CTD PMID:20458559 dibutyl phthalate increases expression ISO RGD:732282 6480464 Dibutyl Phthalate results in increased expression of ALAS2 mRNA CTD PMID:21266533 dichloroacetic acid decreases expression ISO RGD:732282 6480464 Dichloroacetic Acid results in decreased expression of ALAS2 mRNA CTD PMID:28962523 diclofenac affects expression ISO RGD:736755 6480464 Diclofenac affects the expression of ALAS2 mRNA CTD PMID:24752500 dimethyl sulfoxide increases expression ISO RGD:732282 6480464 Dimethyl Sulfoxide results in increased expression of ALAS2 mRNA CTD PMID:21296123 dioxygen multiple interactions ISO RGD:732282 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of ALAS2 mRNA CTD PMID:30529165 doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of ALAS2 mRNA CTD PMID:19915844 doxorubicin decreases expression ISO RGD:732282 6480464 Doxorubicin results in decreased expression of ALAS2 mRNA CTD PMID:28608983 ethanol affects expression ISO RGD:732282 6480464 Ethanol affects the expression of ALAS2 mRNA CTD PMID:19167417 ferroheme b decreases expression ISO RGD:732282 6480464 Heme metabolite results in decreased expression of ALAS2 mRNA CTD PMID:19191707 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of ALAS2 mRNA CTD PMID:22061828 heme b decreases expression ISO RGD:732282 6480464 Heme metabolite results in decreased expression of ALAS2 mRNA CTD PMID:19191707 hemin multiple interactions ISO RGD:736755 6480464 [catechol co-treated with Hemin] results in increased expression of ALAS2 mRNA more ... CTD PMID:23973255 more ... hemin increases expression ISO RGD:736755 6480464 Hemin results in increased expression of ALAS2 mRNA CTD PMID:23973255 , PMID:28552822 hexachlorobenzene increases expression EXP 6480464 Hexachlorobenzene results in increased expression of ALAS2 mRNA CTD PMID:15159207 indole-3-methanol affects expression EXP 6480464 indole-3-carbinol affects the expression of ALAS2 mRNA CTD PMID:21396975 irinotecan increases expression ISO RGD:736755 6480464 Irinotecan metabolite results in increased expression of ALAS2 mRNA, Irinotecan results in increased expression of ALAS2 mRNA CTD PMID:15956246 iron atom increases expression ISO RGD:732282 6480464 Iron results in increased expression of ALAS2 mRNA CTD PMID:16424395 iron(0) increases expression ISO RGD:732282 6480464 Iron results in increased expression of ALAS2 mRNA CTD PMID:16424395 lead diacetate increases expression EXP 6480464 lead acetate results in increased expression of ALAS2 mRNA CTD PMID:22641619 linalool decreases expression EXP 6480464 linalool results in decreased expression of ALAS2 mRNA CTD PMID:20536181 linezolid decreases expression EXP 6480464 Linezolid results in decreased expression of ALAS2 mRNA CTD PMID:21296123 maneb multiple interactions ISO RGD:732282 6480464 [Paraquat co-treated with Maneb] affects the expression of ALAS2 mRNA CTD PMID:22563483 metformin decreases expression EXP 6480464 Metformin results in decreased expression of ALAS2 mRNA CTD PMID:31324951 methimazole increases expression EXP 6480464 Methimazole results in increased expression of ALAS2 mRNA CTD PMID:20144635 methotrexate decreases expression EXP 6480464 Methotrexate results in decreased expression of ALAS2 mRNA CTD PMID:16005536 , PMID:24136188 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ALAS2 mRNA CTD PMID:18164116 N-nitrosodiethylamine decreases expression ISO RGD:732282 6480464 Diethylnitrosamine results in decreased expression of ALAS2 mRNA CTD PMID:24535843 nitrofen increases expression EXP 6480464 nitrofen results in increased expression of ALAS2 mRNA CTD PMID:33484710 ozone decreases expression ISO RGD:732282 6480464 Ozone results in decreased expression of ALAS2 mRNA CTD PMID:12763052 paracetamol affects expression ISO RGD:732282 6480464 Acetaminophen affects the expression of ALAS2 mRNA CTD PMID:15606129 , PMID:17562736 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of ALAS2 mRNA CTD PMID:30723492 paracetamol decreases expression ISO RGD:732282 6480464 Acetaminophen results in decreased expression of ALAS2 mRNA CTD PMID:29246445 paracetamol multiple interactions ISO RGD:732282 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of ALAS2 mRNA more ... CTD PMID:17585979 , PMID:29246445 paraquat multiple interactions ISO RGD:732282 6480464 [Paraquat co-treated with Maneb] affects the expression of ALAS2 mRNA CTD PMID:22563483 phenacetin increases expression EXP 6480464 Phenacetin results in increased expression of ALAS2 mRNA CTD PMID:17082564 phenformin decreases expression EXP 6480464 Phenformin results in decreased expression of ALAS2 mRNA CTD PMID:31324951 phenol multiple interactions ISO RGD:736755 6480464 Phenol inhibits the reaction [Hemin results in increased expression of ALAS2 mRNA] CTD PMID:23973255 phenylhydrazine increases expression EXP 6480464 phenylhydrazine results in increased expression of ALAS2 mRNA CTD PMID:17082564 pirinixic acid multiple interactions ISO RGD:732282 6480464 [pirinixic acid co-treated with PPARA] results in decreased expression of ALAS2 mRNA, PPARA protein promotes the reaction [pirinixic acid results in decreased expression of ALAS2 mRNA] CTD PMID:20059764 , PMID:20813756 pirinixic acid decreases expression ISO RGD:732282 6480464 pirinixic acid results in decreased expression of ALAS2 mRNA CTD PMID:15302862 more ... pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of ALAS2 mRNA CTD PMID:19162173 potassium dichromate decreases expression ISO RGD:732282 6480464 Potassium Dichromate results in decreased expression of ALAS2 mRNA CTD PMID:23608068 progesterone affects expression ISO RGD:732282 6480464 Progesterone affects the expression of ALAS2 mRNA CTD PMID:17251523 raloxifene affects expression EXP 6480464 Raloxifene Hydrochloride affects the expression of ALAS2 mRNA CTD PMID:16079270 rotenone affects expression EXP 6480464 Rotenone affects the expression of ALAS2 mRNA CTD PMID:28374803 S-adenosyl-L-homocysteine multiple interactions ISO RGD:736755 6480464 [S-Adenosylhomocysteine co-treated with Hemin] results in increased expression of ALAS2 mRNA, catechol inhibits the reaction [[S-Adenosylhomocysteine co-treated with Hemin] results in increased expression of ALAS2 mRNA] CTD PMID:24141029 S-adenosyl-L-methioninate multiple interactions ISO RGD:736755 6480464 [S-Adenosylmethionine co-treated with Hemin] results in increased expression of ALAS2 mRNA, catechol inhibits the reaction [[S-Adenosylmethionine co-treated with Hemin] results in increased expression of ALAS2 mRNA] CTD PMID:24141029 S-adenosyl-L-methionine multiple interactions ISO RGD:736755 6480464 [S-Adenosylmethionine co-treated with Hemin] results in increased expression of ALAS2 mRNA, catechol inhibits the reaction [[S-Adenosylmethionine co-treated with Hemin] results in increased expression of ALAS2 mRNA] CTD PMID:24141029 sodium arsenate decreases expression ISO RGD:732282 6480464 sodium arsenate results in decreased expression of ALAS2 mRNA CTD PMID:21795629 sodium arsenate increases expression ISO RGD:732282 6480464 sodium arsenate results in increased expression of ALAS2 mRNA CTD PMID:30953684 sodium arsenite decreases expression ISO RGD:732282 6480464 sodium arsenite results in decreased expression of ALAS2 mRNA CTD PMID:17682005 sodium dichromate decreases expression ISO RGD:732282 6480464 sodium bichromate results in decreased expression of ALAS2 mRNA CTD PMID:22155349 testosterone increases expression ISO RGD:732282 6480464 Testosterone results in increased expression of ALAS2 mRNA CTD PMID:21669218 tetrachloromethane decreases expression ISO RGD:732282 6480464 Carbon Tetrachloride results in decreased expression of ALAS2 mRNA CTD PMID:27339419 , PMID:31919559 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of ALAS2 mRNA CTD PMID:30723492 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of ALAS2 mRNA CTD PMID:23411599 tioguanine decreases expression EXP 6480464 Thioguanine results in decreased expression of ALAS2 mRNA CTD PMID:16005536 trichloroethene decreases methylation EXP 6480464 Trichloroethylene results in decreased methylation of ALAS2 gene CTD PMID:27618143 trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of ALAS2 mRNA CTD PMID:33387578 triphenyl phosphate decreases expression EXP 6480464 triphenyl phosphate results in decreased expression of ALAS2 mRNA CTD PMID:30589522 tungsten decreases expression ISO RGD:732282 6480464 Tungsten results in decreased expression of ALAS2 mRNA CTD PMID:30912803 valproic acid affects expression ISO RGD:732282 6480464 Valproic Acid affects the expression of ALAS2 mRNA CTD PMID:17292431 valproic acid decreases expression ISO RGD:732282 6480464 Valproic Acid results in decreased expression of ALAS2 mRNA CTD PMID:24535564 valproic acid decreases methylation ISO RGD:736755 6480464 Valproic Acid results in decreased methylation of ALAS2 gene CTD PMID:29154799 vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of ALAS2 mRNA CTD PMID:19015723 vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of ALAS2 mRNA CTD PMID:23034163