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Gene: Chst7 (carbohydrate sulfotransferase 7) Rattus norvegicus

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Symbol:

Chst7

Name:

carbohydrate sulfotransferase 7

RGD ID:

1303028

Description:

Predicted to enable N-acetylglucosamine 6-O-sulfotransferase activity and chondroitin 6-sulfotransferase activity. Predicted to be involved in N-acetylglucosamine metabolic process and chondroitin sulfate biosynthetic process. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. Orthologous to human CHST7 (carbohydrate sulfotransferase 7); PARTICIPATES IN chondroitin sulfate biosynthetic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

C6ST-2; carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7; chondroitin 6-sulfotransferase 2; chondroitin 6-sulfotransferase 7; galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 5; glcNAc6ST-4; Gn6st-4; GST-5; MGC124926; N-acetylglucosamine 6-O-sulfotransferase 1; N-acetylglucosamine 6-O-sulfotransferase 4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CHST7 (carbohydrate sulfotransferase 7)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Chst7 (carbohydrate sulfotransferase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Chst7 (carbohydrate sulfotransferase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CHST7 (carbohydrate sulfotransferase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CHST7 (carbohydrate sulfotransferase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Chst7 (carbohydrate sulfotransferase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CHST7 (carbohydrate sulfotransferase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CHST7 (carbohydrate sulfotransferase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Chst7 (carbohydrate sulfotransferase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	CHST7 (carbohydrate sulfotransferase 7)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Chst7 (carbohydrate sulfotransferase 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	chst7 (carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG31637	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG9550	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	chst7	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	4,949,810 - 4,986,372 (-)	NCBI		GRCr8
mRatBN7.2	X	2,396,260 - 2,432,828 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	2,393,874 - 2,432,840 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	2,429,449 - 2,466,021 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	5,905,200 - 5,941,769 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	2,215,569 - 2,252,135 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	2,623,018 - 2,657,155 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	2,623,024 - 2,657,155 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	3,413,400 - 3,449,646 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	13,817,186 - 13,853,694 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	X	13,857,681 - 13,859,139 (-)	NCBI
Celera	X	2,920,778 - 2,957,095 (-)	NCBI		Celera
Cytogenetic Map	X	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Kabuki Syndrome 2 (ISO)

Neurodevelopmental Disorders (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,6-dinitrotoluene (EXP)

5-fluorouracil (ISO)

acrylamide (ISO)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

benzene (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

butan-1-ol (ISO)

calcitriol (ISO)

carbon nanotube (ISO)

cefaloridine (EXP)

CGP 52608 (ISO)

DDE (ISO)

dicrotophos (ISO)

dioxygen (ISO)

ethyl methanesulfonate (ISO)

formaldehyde (ISO)

furan (EXP)

gentamycin (EXP)

hydrogen cyanide (ISO)

lipopolysaccharide (ISO)

menadione (ISO)

methotrexate (ISO)

paracetamol (EXP,ISO)

parathion (ISO)

perfluorohexanesulfonic acid (ISO)

potassium cyanide (ISO)

progesterone (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

sodium arsenite (ISO)

temozolomide (ISO)

tetrachloromethane (EXP)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

trovafloxacin (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

carbohydrate metabolic process (IEA)

chondroitin sulfate biosynthetic process (IBA,ISO)

N-acetylglucosamine metabolic process (IBA,ISO)

sulfur compound metabolic process (ISO)

Cellular Component

Golgi apparatus (ISO)

Golgi membrane (IEA)

Molecular Function

chondroitin 6-sulfotransferase activity (IBA,ISO)

N-acetylglucosamine 6-O-sulfotransferase activity (IBA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

chondroitin sulfate biosynthetic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	An integrated, functionally annotated gene map of the DXS8026-ELK1 interval on human Xp11.3-Xp11.23: potential hotspot for neurogenetic disorders.	Thiselton DL, etal., Genomics 2002 Apr;79(4):560-72.

Additional References at PubMed

PMID:10781596	PMID:10913333	PMID:12477932

Genomics

Comparative Map Data

Chst7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	4,949,810 - 4,986,372 (-)	NCBI		GRCr8
mRatBN7.2	X	2,396,260 - 2,432,828 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	2,393,874 - 2,432,840 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	2,429,449 - 2,466,021 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	5,905,200 - 5,941,769 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	2,215,569 - 2,252,135 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	2,623,018 - 2,657,155 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	2,623,024 - 2,657,155 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	3,413,400 - 3,449,646 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	13,817,186 - 13,853,694 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	X	13,857,681 - 13,859,139 (-)	NCBI
Celera	X	2,920,778 - 2,957,095 (-)	NCBI		Celera
Cytogenetic Map	X	q11	NCBI

CHST7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	46,573,765 - 46,598,496 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	46,573,765 - 46,598,496 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	46,433,200 - 46,457,931 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	46,318,136 - 46,342,782 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	46,189,445 - 46,214,091	NCBI
Celera	X	50,625,034 - 50,649,680 (+)	NCBI		Celera
Cytogenetic Map	X	p11.3	NCBI
HuRef	X	44,144,475 - 44,169,440 (+)	NCBI		HuRef
CHM1_1	X	46,465,351 - 46,489,979 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	45,980,734 - 46,005,466 (+)	NCBI		T2T-CHM13v2.0

Chst7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	19,925,202 - 19,965,361 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	19,925,799 - 19,963,760 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	20,058,963 - 20,099,991 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	20,059,560 - 20,097,521 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	19,636,696 - 19,674,647 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	19,216,529 - 19,254,480 (+)	NCBI		MGSCv36	mm8
Celera	X	18,187,572 - 18,226,625 (+)	NCBI		Celera
Cytogenetic Map	X	A1.3	NCBI
cM Map	X	15.5	NCBI

Chst7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955516	1,461,789 - 1,466,249 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955516	1,435,972 - 1,466,249 (-)	NCBI	ChiLan1.0	ChiLan1.0

CHST7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	48,202,066 - 48,227,010 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	48,205,739 - 48,230,385 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	39,012,011 - 39,036,655 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	46,873,703 - 46,898,117 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	46,873,942 - 46,875,436 (+)	Ensembl	panpan1.1		panPan2

CHST7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	40,209,884 - 40,239,077 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	40,210,096 - 40,211,556 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	14,585,620 - 14,614,974 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	40,343,653 - 40,372,792 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	40,344,040 - 40,345,500 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	40,332,857 - 40,362,003 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	40,319,916 - 40,349,073 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	40,412,644 - 40,442,007 (+)	NCBI		UU_Cfam_GSD_1.0

Chst7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	32,586,021 - 32,605,063 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936502	12,426,851 - 12,445,741 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936502	12,426,821 - 12,446,127 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CHST7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	41,193,025 - 41,233,330 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	41,192,993 - 41,234,654 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	46,035,663 - 46,075,254 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CHST7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	43,780,459 - 43,904,770 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	43,781,196 - 43,782,656 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666076	9,027,115 - 9,053,119 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Chst7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624887	3,381,011 - 3,402,855 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624887	3,381,152 - 3,402,855 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Chst7
112 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	192
Count of miRNA genes:	139
Interacting mature miRNAs:	164
Transcripts:	ENSRNOT00000005630
Prediction methods:	Miranda, Pita, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
70165	Bp64	Blood pressure QTL 64	5.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	X	1448129	31706553	Rat
731181	Uae27	Urinary albumin excretion QTL 27	2.7	0.0059	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	X	1	43491017	Rat
70166	Bp65	Blood pressure QTL 65	5.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	X	1447972	11374346	Rat
634325	Bw13	Body weight QTL 13	0		body mass (VT:0001259)	body weight (CMO:0000012)	X	1447972	20991088	Rat
631204	Gluco15	Glucose level QTL 15		0.001	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	X	1623715	22646544	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	56	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_207600	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AY216524	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC111079	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000005630 ⟹ ENSRNOP00000005630

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	2,393,874 - 2,432,840 (-)	Ensembl
Rnor_6.0 Ensembl	X	2,623,024 - 2,657,155 (-)	Ensembl

RefSeq Acc Id:

NM_207600 ⟹ NP_997483

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	4,949,810 - 4,986,372 (-)	NCBI
mRatBN7.2	X	2,396,260 - 2,432,828 (-)	NCBI
Rnor_6.0	X	2,623,018 - 2,657,155 (-)	NCBI
Rnor_5.0	X	3,413,400 - 3,449,646 (-)	NCBI
RGSC_v3.4	X	13,817,186 - 13,853,694 (-)	RGD
Celera	X	2,920,778 - 2,957,095 (-)	RGD

Sequence:

show sequence

CAGCGTTGAGGGAGACCCGAAGAAGCCGGAGCCGCGGACTCTGGGTGGGTTTTCGGGACAGAAC
TACCAGGCACCTACTTTGCTCTGGGGGGAGGGACGATTCGGTGAACTATGAAGGGCCGGCGGCG
GCGGCGCCGAGAGTACTGCAAGTTCACGCTGCTCTTGGCGCTGTACACGCTTCTGCTACTGCTC
GTCCCCTCTGTACTGGACAGTGGCAGCGAGCAGGACAAGGGCGGCAGGGACTGCCCCGGCCTGC
AGCGCAGCTTGGGTGTGTGGAGCCTGGAGGCGGCGGCGGCCGGGGAACGTGAGCAGGGCGCAGA
GGTGCGGTTCCAGGCCGAAGGAAACCCGGATCGATCCCCTCGGCCCCAGGGCAACCTCAGCGCC
ATCCGTGAGTCCGTGACCCAGGAGAAGCAGCACATCTATGTGCATGCCACCTGGCGCACCGGCT
CGTCCTTCTTGGGTGAACTCTTTAACCAGCACCCGGACGTTTTCTACTTGTACGAGCCCATGTG
GCATCTGTGGCAGGCACTGTATCCGGGCAATGCGGAAAGCCTGCAGGGCGCGCTGAGAGACATG
CTGCGCTCCCTCTTCCGCTGTGATTTCTCTGTGCTCCGCCTGTACGCGCAGCCCGGGGACCCCG
CAGAGCGAGCACCGGACTCGGCCAACCTCACCACGGCCATGCTTTTCCGTTGGCGGACCAACAA
GGTCATCTGCTCGCCGCCTCTGTGCCCCGCCGCGCCCCGGGCGCGCGCGGACGTGGGCCTCGTC
GAGGACAAAGCCTGTGAAAGTACCTGCCCGCCCGTGCCGCTCCGCGCCCTGGAGGCCGAGTGCC
GCAAGTACCCGGTGGTGGTCATCAAGGACGTGCGGCTGCTGGACCTGGGCGTGTTGGTCCCCCT
GCTGCGTGACCCAGGCCTCAACCTGAAGGTAGTGCAGCTCTTCCGAGACCCACGGGCAGTGCAC
AACTCGCGCCTCAAGTCGAGGCACGGACTGCTGCGCGAAAGCATCCAGGTGCTGCGCACACGCC
AGAGAGGTGACCGCTTCCAGCGGGTGCTACTGGCGCACGGCGTGGGTGCCCGTCCCGGAGGCCA
GTCCCGGGCGCTGCCCTCCGCGCCACGCGCCGATTTCTTCTTAACCAGTGCGCTCGAGGTGATC
TGCGAGGCCTGGCTGCGCGATCTGCTCTTCACCCGCGGTGCGCCCACCTGGCTGAGGCGTCGCT
ACCTGCGGCTGCGTTATGAGGACTTGGTGTGGCAGCCCCAAGTCCAGCTGCGCCGCCTGCTGCG
CTTCTCCGGGCTGCGGACACTCGCCGCGCTTGATGCCTTCGCATTCAATATGACCCGCGGCTCG
GCCTATGGAGCCGATAGGCCCTTCCACTTGTCTGCGCGGGACGCCCGAGAGGCTGTGCACGCGT
GGCGCGAGCGTCTGAGCCAAGAGCAGGTGCGCCAGGTGGAGGCCGCTTGCGACCCCGCCATGCG
ACTGCTCGCCTACCCTCGCAGCGGGGATGAACGCGATGTGAAGACCGTCAGGAAAGGGGAGACA
CCACTGGAAACCAACGCCAACTGGGCCACATAGCACCCTGATCCCTGAACCCTGCCCCGGGGCA
TATCTAGGTCAGTGGTTATAAACAGGTGAGCTCGGCATGCTGCACCAACACTGAAGAGGCTGCA
CAGTGGAGGCACTCTATCTCACTGTTAGACACTGGGACTGATTTGGTACCAACTGCTGTGCAAA
TCTGCTGGTCAGGAACATTACAAGCTGTTAAGCGATGACAAACACATTGGCTGAGATGAAGTTT
CCAGAAAGGAAGTGGTGGTGCAATGTGGATATTTGTGACCATAAAATAGGAAAAGTTTTACTTC
CCAGGCTTAACTTGGCTGGGCTTAAGCCATTTCAACAAGGCATTCTCACAACAAAGAAGAGATA
TGATCTGGTTCCATTTCATATCAGCAGATGTCTGGACAAAACCATCAATGTGACTAAGGGCCAA
GTGCTACTATGTCTATCTTGATTAAGTTACTTCATATTAAATAAAAGGTCTGGCTGGTATTGTT
TCCAAAAGGCCTCATCCAGCTCTCCTTCAATTAGCAGTCTTCCTATAGAACCATTTCCTAAACA
GTTTTCCCTGGTGGGTAGGAGAGTTGTAATAAACTAAACCTTTTTTGTTTTCAAAATTTTCTAT
CTAGTTGTTTTTTAACTCTGCAGTTAAATGACTGTAGCATCATACTAATGACATGACTTTGGGG
GGAGAGGGATAAGCAGATTTTGTTAAGTGGCTCAATTGTATGAATTCAATAAAGGCAGTCTATA
TAAAAGAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_997483	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI11080	(Get FASTA)	NCBI Sequence Viewer
	AAP51034	(Get FASTA)	NCBI Sequence Viewer
	EDL97689	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000005630.4
GenBank Protein	Q6XQG8	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_997483 ⟸ NM_207600
- Peptide Label:	precursor
- UniProtKB:	Q6XQG8 (UniProtKB/Swiss-Prot), Q2TA65 (UniProtKB/Swiss-Prot), A6JZU6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKGRRRRRREYCKFTLLLALYTLLLLLVPSVLDSGSEQDKGGRDCPGLQRSLGVWSLEAAAAGE REQGAEVRFQAEGNPDRSPRPQGNLSAIRESVTQEKQHIYVHATWRTGSSFLGELFNQHPDVFY LYEPMWHLWQALYPGNAESLQGALRDMLRSLFRCDFSVLRLYAQPGDPAERAPDSANLTTAMLF RWRTNKVICSPPLCPAAPRARADVGLVEDKACESTCPPVPLRALEAECRKYPVVVIKDVRLLDL GVLVPLLRDPGLNLKVVQLFRDPRAVHNSRLKSRHGLLRESIQVLRTRQRGDRFQRVLLAHGVG ARPGGQSRALPSAPRADFFLTSALEVICEAWLRDLLFTRGAPTWLRRRYLRLRYEDLVWQPQVQ LRRLLRFSGLRTLAALDAFAFNMTRGSAYGADRPFHLSARDAREAVHAWRERLSQEQVRQVEAA CDPAMRLLAYPRSGDERDVKTVRKGETPLETNANWAT hide sequence

Ensembl Acc Id:

ENSRNOP00000005630 ⟸ ENSRNOT00000005630

Protein Domains

Sulfotransferase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6XQG8-F1-model_v2	AlphaFold	Q6XQG8	1-485	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1303028	AgrOrtholog
BioCyc Gene	G2FUF-3170	BioCyc
BioCyc Pathway	PWY-6567 [chondroitin sulfate biosynthesis]	BioCyc
BioCyc Pathway Image	PWY-6567	BioCyc
Ensembl Genes	ENSRNOG00000004258	Ensembl, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000005630.6	UniProtKB/Swiss-Prot
Gene3D-CATH	3.40.50.300	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7387313	IMAGE-MGC_LOAD
InterPro	Carbohydrate_sulfotransferase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Gal/GlcNAc/GalNAc_ST	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Sulfotransferase_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:302302	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:124926	IMAGE-MGC_LOAD
NCBI Gene	302302	ENTREZGENE
PANTHER	CARBOHYDRATE SULFOTRANSFERASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CARBOHYDRATE SULFOTRANSFERASE 7	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Sulfotransfer_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Chst7	PhenoGen
PIRSF	Carbohydrate_sulfotransferase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000004258	RatGTEx
	ENSRNOG00055016635	RatGTEx
	ENSRNOG00060022654	RatGTEx
	ENSRNOG00065020594	RatGTEx
Superfamily-SCOP	P-loop containing nucleoside triphosphate hydrolases	UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt	A6JZU6	ENTREZGENE, UniProtKB/TrEMBL
	CHST7_RAT	UniProtKB/Swiss-Prot
	Q2TA65	ENTREZGENE
	Q6XQG8	ENTREZGENE
UniProt Secondary	Q2TA65	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-03-29	Chst7	carbohydrate sulfotransferase 7	Chst7	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2009-12-15	Chst7	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7	Chst7	carbohydrate sulfotransferase 7	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2009-11-05	Chst7	carbohydrate sulfotransferase 7	Chst7	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Chst7	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7			Symbol and Name status set to approved	1299863	APPROVED
2005-02-14	Chst7	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

BioCyc Pathways

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Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

BioCyc Pathways