Chst7 (carbohydrate sulfotransferase 7) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Chst7 (carbohydrate sulfotransferase 7) Mus musculus
Analyze
Symbol: Chst7
Name: carbohydrate sulfotransferase 7 (Ensembl:carbohydrate (N-acetylglucosamino) sulfotransferase 7)
RGD ID: 1552383
MGI Page MGI
Description: Enables chondroitin 6-sulfotransferase activity. Predicted to be involved in N-acetylglucosamine metabolic process and chondroitin sulfate biosynthetic process. Is active in Golgi apparatus. Is expressed in several structures, including brain; endocrine gland; immune system; respiratory system; and tail unsegmented mesenchyme. Orthologous to human CHST7 (carbohydrate sulfotransferase 7).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2600013M07Rik; C6ST-; C6ST-2; carbohydrate (N-acetylglucosamino) sulfotransferase 7; chondroitin 6-sulfotransferase 2; galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 5; glcNAc6ST-4; Gn6st-4; GST; GST-5; GST5; mC6ST-2; N-acetylglucosamine 6-O-sulfotransferase 1; N-acetylglucosamine 6-O-sulfotransferase 4
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X19,925,202 - 19,965,361 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX19,925,799 - 19,963,760 (+)EnsemblGRCm39 Ensembl
GRCm38X20,058,963 - 20,099,991 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX20,059,560 - 20,097,521 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X19,636,696 - 19,674,647 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X19,216,529 - 19,254,480 (+)NCBIMGSCv36mm8
CeleraX18,187,572 - 18,226,625 (+)NCBICelera
Cytogenetic MapXA1.3NCBI
cM MapX15.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:6781479   PMID:8889548   PMID:10349636   PMID:10781596   PMID:10913333   PMID:10956661   PMID:11042159   PMID:11076861   PMID:11181564   PMID:12477932   PMID:14681479   PMID:15489334  
PMID:16141072   PMID:16141073   PMID:18079434   PMID:21873635   PMID:29555813   PMID:30867513   PMID:34169071  


Genomics

Comparative Map Data
Chst7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X19,925,202 - 19,965,361 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX19,925,799 - 19,963,760 (+)EnsemblGRCm39 Ensembl
GRCm38X20,058,963 - 20,099,991 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX20,059,560 - 20,097,521 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X19,636,696 - 19,674,647 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X19,216,529 - 19,254,480 (+)NCBIMGSCv36mm8
CeleraX18,187,572 - 18,226,625 (+)NCBICelera
Cytogenetic MapXA1.3NCBI
cM MapX15.5NCBI
CHST7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X46,573,765 - 46,598,496 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX46,573,765 - 46,598,496 (+)EnsemblGRCh38hg38GRCh38
GRCh37X46,433,200 - 46,457,931 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X46,318,136 - 46,342,782 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X46,189,445 - 46,214,091NCBI
CeleraX50,625,034 - 50,649,680 (+)NCBICelera
Cytogenetic MapXp11.3NCBI
HuRefX44,144,475 - 44,169,440 (+)NCBIHuRef
CHM1_1X46,465,351 - 46,489,979 (+)NCBICHM1_1
T2T-CHM13v2.0X45,980,734 - 46,005,466 (+)NCBIT2T-CHM13v2.0
Chst7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X4,949,810 - 4,986,372 (-)NCBIGRCr8
mRatBN7.2X2,396,260 - 2,432,828 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX2,393,874 - 2,432,840 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX2,429,449 - 2,466,021 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X5,905,200 - 5,941,769 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X2,215,569 - 2,252,135 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X2,623,018 - 2,657,155 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX2,623,024 - 2,657,155 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X3,413,400 - 3,449,646 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X13,817,186 - 13,853,694 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X13,857,681 - 13,859,139 (-)NCBI
CeleraX2,920,778 - 2,957,095 (-)NCBICelera
Cytogenetic MapXq11NCBI
Chst7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555161,461,789 - 1,466,249 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555161,435,972 - 1,466,249 (-)NCBIChiLan1.0ChiLan1.0
CHST7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X48,202,066 - 48,227,010 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X48,205,739 - 48,230,385 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X39,012,011 - 39,036,655 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X46,873,703 - 46,898,117 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX46,873,942 - 46,875,436 (+)Ensemblpanpan1.1panPan2
CHST7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X40,209,884 - 40,239,077 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX40,210,096 - 40,211,556 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX14,585,620 - 14,614,974 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X40,343,653 - 40,372,792 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX40,344,040 - 40,345,500 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X40,332,857 - 40,362,003 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X40,319,916 - 40,349,073 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X40,412,644 - 40,442,007 (+)NCBIUU_Cfam_GSD_1.0
Chst7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X32,586,021 - 32,605,063 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650212,426,851 - 12,445,741 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650212,426,821 - 12,446,127 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHST7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX41,193,025 - 41,233,330 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X41,192,993 - 41,234,654 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X46,035,663 - 46,075,254 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CHST7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X43,780,459 - 43,904,770 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX43,781,196 - 43,782,656 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660769,027,115 - 9,053,119 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Chst7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248873,381,011 - 3,402,855 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248873,381,152 - 3,402,855 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Chst7
719 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:249
Count of miRNA genes:194
Interacting mature miRNAs:219
Transcripts:ENSMUST00000044138
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302195Pbwg10_mpostnatal body weight growth 10 (mouse)Not determinedX126202173Mouse
1357433Dbts2_mdiabetes 2 (mouse)Not determinedX7226295150107038Mouse
1301551Spha1_msperm head anomaly 1 (mouse)Not determinedX1026622539921652Mouse
13208553Wght11_mweight 11 (mouse)X1186623959045360Mouse
13208557Lgth13_mbody length 13 (mouse)X1186623959045360Mouse

Markers in Region
Chst7  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X20,059,791 - 20,060,317UniSTSGRCm38
MGSCv37X19,636,917 - 19,637,443UniSTSGRCm37
CeleraX18,187,793 - 18,188,319UniSTS
Cytogenetic MapXA3.1-A3.2UniSTS
cM MapX UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000044138   ⟹   ENSMUSP00000043222
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblX19,925,799 - 19,963,760 (+)Ensembl
GRCm38.p6 EnsemblX20,059,560 - 20,097,521 (+)Ensembl
RefSeq Acc Id: NM_021715   ⟹   NP_068361
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X19,925,809 - 19,963,760 (+)NCBI
GRCm38X20,059,570 - 20,097,521 (+)NCBI
MGSCv37X19,636,696 - 19,674,647 (+)RGD
CeleraX18,187,572 - 18,226,625 (+)RGD
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: XR_878032
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X19,925,202 - 19,965,361 (+)NCBI
GRCm38X20,058,963 - 20,099,991 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_068361   ⟸   NM_021715
- Peptide Label: precursor
- UniProtKB: Q99NB0 (UniProtKB/Swiss-Prot),   Q9EP78 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000043222   ⟸   ENSMUST00000044138

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9EP78-F1-model_v2 AlphaFold Q9EP78 1-484 view protein structure

Promoters
RGD ID:6845560
Promoter ID:MM_KWN:59716
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000041312
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X19,636,526 - 19,637,767 (+)MPROMDB
RGD ID:13680170
Promoter ID:EPDNEW_M24234
Type:initiation region
Name:Chst7_1
Description:Mus musculus carbohydrate (N-acetylglucosamino) sulfotransferase7 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X20,059,551 - 20,059,611EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1891767 AgrOrtholog
Ensembl Genes ENSMUSG00000037347 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000044138 ENTREZGENE
  ENSMUST00000044138.8 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot
InterPro Carbohydrate_sulfotransferase UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  Sulfotransferase_dom UniProtKB/Swiss-Prot
KEGG Report mmu:60322 UniProtKB/Swiss-Prot
MGD MGI:1891767 ENTREZGENE
NCBI Gene 60322 ENTREZGENE
PANTHER CARBOHYDRATE SULFOTRANSFERASE UniProtKB/Swiss-Prot
  CARBOHYDRATE SULFOTRANSFERASE 7 UniProtKB/Swiss-Prot
Pfam Sulfotransfer_1 UniProtKB/Swiss-Prot
PhenoGen Chst7 PhenoGen
PIRSF Carbohydrate_sulfotransferase UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt CHST7_MOUSE UniProtKB/Swiss-Prot
  Q99NB0 ENTREZGENE
  Q9EP78 ENTREZGENE
UniProt Secondary Q99NB0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-07-04 Chst7  carbohydrate sulfotransferase 7  Chst7  carbohydrate (N-acetylglucosamino) sulfotransferase 7  Symbol and/or name change 5135510 APPROVED