Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of DYNLT3 mRNA] | CTD | PMID:31150632 | (-)-alpha-phellandrene | increases expression | ISO | DYNLT3 (Homo sapiens) | 6480464 | alpha phellandrene results in increased expression of DYNLT3 mRNA | CTD | PMID:25075043 | 1,2-dimethylhydrazine | multiple interactions | ISO | Dynlt3 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DYNLT3 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | decreases expression | ISO | Dynlt3 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of DYNLT3 mRNA | CTD | PMID:22206623 | 17beta-estradiol | multiple interactions | ISO | DYNLT3 (Homo sapiens) | 6480464 | EGF protein promotes the reaction [Estradiol results in increased expression of DYNLT3 mRNA] | CTD | PMID:24758408 | 17beta-estradiol | increases expression | ISO | DYNLT3 (Homo sapiens) | 6480464 | Estradiol results in increased expression of DYNLT3 mRNA | CTD | PMID:24758408 and PMID:31614463 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of DYNLT3 mRNA | CTD | PMID:21215274 and PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Dynlt3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of DYNLT3 mRNA | CTD | PMID:15034205 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Dynlt3 (Mus musculus) | 6480464 | AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of DYNLT3 mRNA] | CTD | PMID:15034205 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Dynlt3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of DYNLT3 mRNA | CTD | PMID:21570461 | 2-hydroxypropanoic acid | affects expression | ISO | DYNLT3 (Homo sapiens) | 6480464 | Lactic Acid affects the expression of DYNLT3 mRNA | CTD | PMID:30851411 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | DYNLT3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of DYNLT3 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | DYNLT3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of DYNLT3 mRNA | CTD | PMID:28628672 | 4-hydroxynon-2-enal | affects binding | ISO | DYNLT3 (Homo sapiens) | 6480464 | DYNLT3 protein binds to 4-hydroxy-2-nonenal | CTD | PMID:20043646 | aflatoxin B1 | increases expression | ISO | Dynlt3 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of DYNLT3 mRNA | CTD | PMID:19770486 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of DYNLT3 mRNA | CTD | PMID:33354967 | alpha-phellandrene | increases expression | ISO | DYNLT3 (Homo sapiens) | 6480464 | alpha phellandrene results in increased expression of DYNLT3 mRNA | CTD | PMID:25075043 | antimycin A | decreases expression | ISO | DYNLT3 (Homo sapiens) | 6480464 | Antimycin A results in decreased expression of DYNLT3 mRNA | CTD | PMID:33512557 | Aroclor 1254 | decreases expression | ISO | Dynlt3 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of DYNLT3 mRNA | CTD | PMID:23650126 | benzo[a]pyrene | multiple interactions | ISO | Dynlt3 (Mus musculus) | 6480464 | AHR protein inhibits the reaction [Benzo(a)pyrene results in increased expression of DYNLT3 mRNA] | CTD | PMID:15034205 | benzo[a]pyrene | decreases methylation | ISO | DYNLT3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of DYNLT3 3' UTR | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | DYNLT3 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of DYNLT3 exon | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | ISO | DYNLT3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of DYNLT3 promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | Dynlt3 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of DYNLT3 mRNA | CTD | PMID:15034205 and PMID:22228805 | bis(2-ethylhexyl) phthalate | increases expression | ISO | DYNLT3 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in increased expression of DYNLT3 mRNA | CTD | PMID:31163220 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of DYNLT3 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | Dynlt3 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of DYNLT3 mRNA | CTD | PMID:33221593 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of DYNLT3 mRNA | CTD | PMID:34947998 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of DYNLT3 gene | CTD | PMID:28505145 | buspirone | decreases expression | EXP | | 6480464 | Buspirone results in decreased expression of DYNLT3 mRNA | CTD | PMID:24136188 | butanal | increases expression | ISO | DYNLT3 (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of DYNLT3 mRNA | CTD | PMID:26079696 | captan | increases expression | ISO | Dynlt3 (Mus musculus) | 6480464 | Captan results in increased expression of DYNLT3 mRNA | CTD | PMID:31558096 | carbamazepine | affects expression | ISO | DYNLT3 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of DYNLT3 mRNA | CTD | PMID:25979313 | carbon nanotube | decreases expression | ISO | Dynlt3 (Mus musculus) | 6480464 | Nanotubes and Carbon results in decreased expression of DYNLT3 mRNA | CTD | PMID:25620056 | CGP 52608 | multiple interactions | ISO | DYNLT3 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to DYNLT3 gene] | CTD | PMID:28238834 | chlormequat chloride | increases expression | EXP | | 6480464 | Chlormequat results in increased expression of DYNLT3 protein | CTD | PMID:34958886 | cisplatin | increases expression | ISO | DYNLT3 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of DYNLT3 mRNA | CTD | PMID:27594783 | copper atom | increases expression | ISO | Dynlt3 (Mus musculus) | 6480464 | Copper results in increased expression of DYNLT3 mRNA | CTD | PMID:16629173 | copper(0) | increases expression | ISO | Dynlt3 (Mus musculus) | 6480464 | Copper results in increased expression of DYNLT3 mRNA | CTD | PMID:16629173 | coumestrol | multiple interactions | ISO | DYNLT3 (Homo sapiens) | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of DYNLT3 mRNA | CTD | PMID:19167446 | dexamethasone | multiple interactions | ISO | DYNLT3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of DYNLT3 mRNA | CTD | PMID:28628672 | dicrotophos | decreases expression | ISO | DYNLT3 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of DYNLT3 mRNA | CTD | PMID:28302478 | dioxygen | multiple interactions | ISO | Dynlt3 (Mus musculus) | 6480464 | [sulforaphane affects the susceptibility to Oxygen] which affects the expression of DYNLT3 mRNA | CTD | PMID:30529165 | disodium selenite | increases expression | ISO | DYNLT3 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of DYNLT3 mRNA | CTD | PMID:18175754 | dorsomorphin | multiple interactions | ISO | DYNLT3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DYNLT3 mRNA | CTD | PMID:27188386 | ethanol | affects splicing | ISO | Dynlt3 (Mus musculus) | 6480464 | Ethanol affects the splicing of DYNLT3 mRNA | CTD | PMID:30319688 | folic acid | decreases expression | ISO | Dynlt3 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of DYNLT3 mRNA | CTD | PMID:25629700 | folic acid | multiple interactions | ISO | Dynlt3 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DYNLT3 mRNA | CTD | PMID:22206623 | folpet | increases expression | ISO | Dynlt3 (Mus musculus) | 6480464 | folpet results in increased expression of DYNLT3 mRNA | CTD | PMID:31558096 | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of DYNLT3 mRNA | CTD | PMID:24136188 | indometacin | multiple interactions | ISO | DYNLT3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of DYNLT3 mRNA | CTD | PMID:28628672 | ivermectin | decreases expression | ISO | DYNLT3 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of DYNLT3 protein | CTD | PMID:32959892 | kojic acid | decreases expression | ISO | DYNLT3 (Homo sapiens) | 6480464 | kojic acid results in decreased expression of DYNLT3 mRNA | CTD | PMID:16595896 | lipopolysaccharide | multiple interactions | ISO | DYNLT3 (Homo sapiens) | 6480464 | [Lipopolysaccharides co-treated with resveratrol] results in decreased expression of DYNLT3 mRNA | CTD | PMID:26667767 | miconazole | decreases expression | ISO | Dynlt3 (Mus musculus) | 6480464 | Miconazole results in decreased expression of DYNLT3 mRNA | CTD | PMID:27462272 | monosodium L-glutamate | multiple interactions | ISO | Dynlt3 (Mus musculus) | 6480464 | [Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of DYNLT3 mRNA | CTD | PMID:22078008 | nefazodone | decreases expression | EXP | | 6480464 | nefazodone results in decreased expression of DYNLT3 mRNA | CTD | PMID:24136188 | nimesulide | decreases expression | EXP | | 6480464 | nimesulide results in decreased expression of DYNLT3 mRNA | CTD | PMID:24136188 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of DYNLT3 mRNA | CTD | PMID:33387578 | perfluorohexanesulfonic acid | increases expression | ISO | Dynlt3 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in increased expression of DYNLT3 mRNA | CTD | PMID:37995155 | phenylmercury acetate | increases expression | ISO | DYNLT3 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of DYNLT3 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | DYNLT3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DYNLT3 mRNA | CTD | PMID:27188386 | pirinixic acid | decreases expression | ISO | Dynlt3 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of DYNLT3 mRNA | CTD | PMID:18445702 | potassium chromate | decreases expression | ISO | DYNLT3 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of DYNLT3 mRNA | CTD | PMID:22714537 | propiconazole | decreases expression | ISO | Dynlt3 (Mus musculus) | 6480464 | propiconazole results in decreased expression of DYNLT3 mRNA | CTD | PMID:21278054 | quercetin | increases expression | ISO | DYNLT3 (Homo sapiens) | 6480464 | Quercetin results in increased expression of DYNLT3 mRNA | CTD | PMID:21632981 | rac-lactic acid | affects expression | ISO | DYNLT3 (Homo sapiens) | 6480464 | Lactic Acid affects the expression of DYNLT3 mRNA | CTD | PMID:30851411 | resveratrol | multiple interactions | ISO | DYNLT3 (Homo sapiens) | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of DYNLT3 mRNA and [Lipopolysaccharides co-treated with resveratrol] results in decreased expression of DYNLT3 mRNA | CTD | PMID:19167446 and PMID:26667767 | rotenone | increases expression | ISO | DYNLT3 (Homo sapiens) | 6480464 | Rotenone results in increased expression of DYNLT3 mRNA | CTD | PMID:33512557 | SB 431542 | multiple interactions | ISO | DYNLT3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DYNLT3 mRNA | CTD | PMID:27188386 | silicon dioxide | increases methylation | ISO | DYNLT3 (Homo sapiens) | 6480464 | Silicon Dioxide results in increased methylation of DYNLT3 gene | CTD | PMID:34973136 | sodium arsenate | increases expression | ISO | Dynlt3 (Mus musculus) | 6480464 | sodium arsenate results in increased expression of DYNLT3 mRNA | CTD | PMID:21795629 | sulforaphane | multiple interactions | ISO | Dynlt3 (Mus musculus) | 6480464 | [sulforaphane affects the susceptibility to Oxygen] which affects the expression of DYNLT3 mRNA | CTD | PMID:30529165 | testosterone | decreases expression | ISO | Dynlt3 (Mus musculus) | 6480464 | Testosterone results in decreased expression of DYNLT3 mRNA | CTD | PMID:21669218 | tetrachloromethane | affects expression | ISO | Dynlt3 (Mus musculus) | 6480464 | Carbon Tetrachloride affects the expression of DYNLT3 mRNA | CTD | PMID:17484886 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of DYNLT3 mRNA | CTD | PMID:31150632 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of DYNLT3 mRNA] | CTD | PMID:31150632 | tolcapone | decreases expression | EXP | | 6480464 | tolcapone results in decreased expression of DYNLT3 mRNA | CTD | PMID:24136188 | trichostatin A | affects expression | ISO | DYNLT3 (Homo sapiens) | 6480464 | trichostatin A affects the expression of DYNLT3 mRNA | CTD | PMID:28542535 | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of DYNLT3 mRNA | CTD | PMID:23869203 | |