Maob (monoamine oxidase B) - Rat Genome Database

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Gene: Maob (monoamine oxidase B) Rattus norvegicus
Analyze
Symbol: Maob
Name: monoamine oxidase B
RGD ID: 3041
Description: Enables flavin adenine dinucleotide binding activity; identical protein binding activity; and oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor. Involved in several processes, including negative regulation of serotonin secretion; positive regulation of dopamine metabolic process; and response to corticosterone. Located in mitochondrial outer membrane. Biomarker of Parkinson's disease and cholestasis. Human ortholog(s) of this gene implicated in Alzheimer's disease and Parkinson's disease. Orthologous to human MAOB (monoamine oxidase B); PARTICIPATES IN citalopram pharmacodynamics pathway; citalopram pharmacokinetics pathway; Parkinson's disease pathway; INTERACTS WITH (+)-schisandrin B; (-)-selegiline; (3,4-dihydroxyphenyl)acetic acid.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: amine oxidase [flavin-containing] B; MAO-B; monoamine oxidase type B; monoamine oxidase-B
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X5,907,327 - 6,010,996 (+)NCBImRatBN7.2
mRatBN7.2 EnsemblX5,907,266 - 6,011,003 (+)Ensembl
Rnor_6.0X6,430,694 - 6,533,520 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX6,430,594 - 6,533,534 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X7,249,779 - 7,352,270 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X17,553,529 - 17,657,852 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X17,606,846 - 17,711,170 (+)NCBI
CeleraX6,397,919 - 6,500,914 (+)NCBICelera
Cytogenetic MapXq11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (ISO)
(+)-schisandrin B  (EXP)
(-)-selegiline  (EXP,ISO)
(3,4-dihydroxyphenyl)acetic acid  (EXP)
(R)-noradrenaline  (ISO)
(S)-amphetamine  (ISO)
1,1-dichloroethene  (ISO)
1,2,3,4-tetrahydroisoquinoline  (ISO)
1,2-dimethylhydrazine  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-phenylethylamine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,4-Methylenedioxyamphetamine  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
amitraz  (EXP)
ammonium chloride  (EXP)
amphetamine  (ISO)
Anetholtrithion  (EXP)
aripiprazole  (EXP)
baclofen  (ISO)
barbituric acid  (EXP)
benzo[a]pyrene  (ISO)
benzyl benzoate  (ISO)
benzyl cinnamate  (ISO)
beta-carboline  (ISO)
bexarotene  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
Brodifacoum  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
chloroform  (EXP)
chlorogenic acid  (ISO)
cis-caffeic acid  (ISO)
clorgyline  (ISO)
clozapine  (ISO)
cocaine  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
Cuprizon  (EXP)
cyanocob(III)alamin  (ISO)
cyclosporin A  (ISO)
dexamethasone  (EXP,ISO)
diazinon  (EXP)
dibutyl phthalate  (EXP)
dichlorvos  (EXP)
diclofenac  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (ISO)
diuron  (EXP)
dopamine  (EXP,ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
emodin  (EXP)
endosulfan  (EXP)
erythromycin estolate  (EXP)
ethanol  (ISO)
fenofibrate  (EXP)
flavonoids  (EXP)
flutamide  (EXP)
folic acid  (ISO)
fucoxanthin  (ISO)
fulvestrant  (ISO)
geraniol  (ISO)
glafenine  (EXP)
glutathione  (ISO)
Heliotrine  (ISO)
heptachlor  (EXP)
homovanillic acid  (EXP)
indol-3-ylacetaldehyde  (ISO)
indometacin  (ISO)
kojic acid  (EXP)
kynuramine  (ISO)
linezolid  (ISO)
menadione  (ISO)
methamphetamine  (ISO)
methapyrilene  (EXP)
methotrexate  (ISO)
methylene blue  (ISO)
methylmercury chloride  (ISO)
monocrotophos  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
nitroglycerin  (EXP)
nitroprusside  (ISO)
olanzapine  (EXP)
oxaliplatin  (EXP)
ozone  (EXP)
Paeonol  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP)
Pargyline  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phencyclidine  (ISO)
Phenelzine  (ISO)
phenobarbital  (ISO)
phenylephrine  (ISO)
phenylpropanolamine  (EXP,ISO)
PhIP  (EXP)
phlorizin  (ISO)
phosphamidon  (EXP)
pioglitazone  (ISO)
piperine  (EXP)
pirinixic acid  (EXP)
progesterone  (ISO)
quercetin  (ISO)
rasagiline  (ISO)
resveratrol  (EXP,ISO)
risperidone  (EXP)
rosmarinic acid  (ISO)
SB 431542  (ISO)
Senkirkine  (ISO)
serotonin  (ISO)
sertraline  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
simazine  (ISO)
sodium dichromate  (EXP)
sodium fluoride  (ISO)
sulindac  (EXP)
sunitinib  (ISO)
tamoxifen  (EXP)
Tanshinone I  (ISO)
tauroursodeoxycholic acid  (EXP)
tetrachloromethane  (EXP,ISO)
tetracycline  (EXP,ISO)
thioacetamide  (EXP)
thiouracil  (EXP)
topotecan  (EXP)
trans-caffeic acid  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
troglitazone  (ISO)
tryptamine  (ISO)
undecane  (EXP)
uranium atom  (ISO)
urethane  (ISO)
ursodeoxycholic acid  (EXP)
valproic acid  (ISO)
vorinostat  (ISO)
zonisamide  (ISO)

References

References - curated
1. Arai R, etal., Neuroscience 2002;114(4):825-35.
2. Birgner C, etal., Brain Res. 2008 Jul 11;1219:103-10. Epub 2008 May 17.
3. Castoldi AF, etal., Brain Res. 2006 Sep 27;1112(1):91-8. Epub 2006 Aug 10.
4. Costa P, etal., Am J Med Genet 1997 Apr 18;74(2):154-6.
5. Ekuni D, etal., Am J Pathol. 2009 Oct;175(4):1398-409. Epub 2009 Sep 24.
6. Falk EM, etal., Pharmacol Biochem Behav. 2002 Jun;72(3):617-22.
7. Finberg JP and Sader-Mazbar O, J Neural Transm. 2007;114(6):801-5. Epub 2007 Apr 10.
8. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
9. GOA data from the GO Consortium
10. Huang YH, etal., Eur J Histochem. 2008 Jan-Mar;52(1):11-8.
11. Ito A, etal., Biochem Biophys Res Commun 1988 Dec 30;157(3):970-6.
12. KEGG
13. Khudoerkov RM, etal., Bull Exp Biol Med. 2007 Jul;144(1):36-8.
14. Lindley SE, etal., Psychoneuroendocrinology. 2005 Sep;30(8):785-90.
15. MGD data from the GO Consortium
16. NCBI rat LocusLink and RefSeq merged data July 26, 2002
17. O'Carroll AM, etal., Neurochem Int. 1986;8(4):493-500. doi: 10.1016/0197-0186(86)90182-8.
18. Ou XM, etal., Biol Psychiatry. 2009 Dec 18.
19. Pipeline to import KEGG annotations from KEGG into RGD
20. Pipeline to import SMPDB annotations from SMPDB into RGD
21. RGD automated data pipeline
22. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
23. RGD automated import pipeline for gene-chemical interactions
24. Sherif F, etal., J Neural Transm Park Dis Dement Sect. 1992;4(3):227-40.
25. Tang YL, etal., Br J Nutr. 2008 Sep;100(3):660-5. Epub 2008 Feb 28.
26. Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
27. Upadhyay AK and Edmondson DE, Protein Expr Purif. 2008 Jun;59(2):349-56. Epub 2008 Mar 10.
28. Upadhyay AK, etal., Biochemistry. 2008 Feb 12;47(6):1554-66. Epub 2008 Jan 17.
29. Zhang J, etal., Saudi Med J. 2009 Jun;30(6):760-6.
30. Zimatkin SM, etal., Neurosci Behav Physiol. 2008 Oct;38(8):807-10. Epub 2008 Sep 18.
Additional References at PubMed
PMID:9162023   PMID:12477932   PMID:12865426   PMID:14697889   PMID:14986002   PMID:15489334   PMID:15526171   PMID:16098487   PMID:18092818   PMID:18614015   PMID:19909795   PMID:20204567  
PMID:20547771   PMID:20833797   PMID:21341713   PMID:21700703   PMID:22926577   PMID:23376485   PMID:27503749   PMID:34244591   PMID:34290084  


Genomics

Comparative Map Data
Maob
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X5,907,327 - 6,010,996 (+)NCBImRatBN7.2
mRatBN7.2 EnsemblX5,907,266 - 6,011,003 (+)Ensembl
Rnor_6.0X6,430,694 - 6,533,520 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX6,430,594 - 6,533,534 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X7,249,779 - 7,352,270 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X17,553,529 - 17,657,852 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X17,606,846 - 17,711,170 (+)NCBI
CeleraX6,397,919 - 6,500,914 (+)NCBICelera
Cytogenetic MapXq11NCBI
MAOB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X43,766,610 - 43,882,450 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 EnsemblX43,766,610 - 43,882,450 (-)EnsemblGRCh38hg38GRCh38
GRCh37X43,625,857 - 43,741,696 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X43,510,801 - 43,626,665 (-)NCBINCBI36hg18NCBI36
Build 34X43,382,111 - 43,497,935NCBI
CeleraX47,765,631 - 47,881,481 (-)NCBI
Cytogenetic MapXp11.3NCBI
HuRefX41,355,388 - 41,470,732 (-)NCBIHuRef
CHM1_1X43,659,020 - 43,774,882 (-)NCBICHM1_1
T2T-CHM13v2.0X43,172,827 - 43,288,647 (-)NCBI
Maob
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X16,575,520 - 16,683,605 (-)NCBIGRCm39mm39
GRCm39 EnsemblX16,575,521 - 16,683,605 (-)Ensembl
GRCm38X16,709,281 - 16,817,366 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX16,709,282 - 16,817,366 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X16,286,407 - 16,394,492 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X15,866,241 - 15,974,323 (-)NCBImm8
CeleraX14,324,831 - 14,433,074 (-)NCBICelera
Cytogenetic MapXA1.2NCBI
cM MapX11.88NCBI
Maob
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555164,328,476 - 4,472,593 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555164,328,286 - 4,473,419 (+)NCBIChiLan1.0ChiLan1.0
MAOB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X44,042,000 - 44,157,846 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX44,042,000 - 44,157,941 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X36,217,710 - 36,333,516 (-)NCBIMhudiblu_PPA_v0panPan3
MAOB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X37,765,810 - 37,883,955 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX37,765,813 - 37,883,955 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX24,993,868 - 25,112,008 (-)NCBI
ROS_Cfam_1.0X37,854,043 - 37,972,251 (-)NCBI
ROS_Cfam_1.0 EnsemblX37,854,043 - 37,972,306 (-)Ensembl
UMICH_Zoey_3.1X37,895,301 - 38,013,405 (-)NCBI
UNSW_CanFamBas_1.0X37,878,280 - 37,996,408 (-)NCBI
UU_Cfam_GSD_1.0X37,973,208 - 38,091,371 (-)NCBI
Maob
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X30,066,432 - 30,229,771 (-)NCBI
SpeTri2.0NW_0049365029,907,181 - 10,014,756 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAOB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX39,025,971 - 39,144,345 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X39,025,973 - 39,144,389 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X43,355,507 - 43,474,320 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MAOB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X40,936,789 - 41,054,547 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 EnsemblX40,936,711 - 41,054,641 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660766,156,035 - 6,274,102 (-)NCBIVero_WHO_p1.0
Maob
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476211,584,825 - 11,720,506 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462476211,584,925 - 11,720,273 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH129056  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X6,010,770 - 6,010,952 (+)MAPPERmRatBN7.2
Rnor_6.0X6,533,295 - 6,533,476NCBIRnor6.0
Rnor_5.0X7,352,045 - 7,352,226UniSTSRnor5.0
RGSC_v3.4X17,657,627 - 17,657,808UniSTSRGSC3.4
CeleraX6,500,689 - 6,500,870UniSTS
Cytogenetic MapXq12UniSTS
RH142419  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X6,010,684 - 6,010,885 (+)MAPPERmRatBN7.2
Rnor_6.0X6,533,209 - 6,533,409NCBIRnor6.0
Rnor_5.0X7,351,959 - 7,352,159UniSTSRnor5.0
RGSC_v3.4X17,657,541 - 17,657,741UniSTSRGSC3.4
CeleraX6,500,603 - 6,500,803UniSTS
Cytogenetic MapXq12UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X143491017Rat
70166Bp65Blood pressure QTL 655.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X144797211374346Rat
634325Bw13Body weight QTL 130body mass (VT:0001259)body weight (CMO:0000012)X144797220991088Rat
70165Bp64Blood pressure QTL 645.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X144812931706553Rat
631204Gluco15Glucose level QTL 150.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)X162371522646544Rat
1298071Edpm12Estrogen-dependent pituitary mass QTL 123.2pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)X292789847927898Rat
10755455Coatc13Coat color QTL 130coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7440600049406000Rat
631666Iddm5Insulin dependent diabetes mellitus QTL 5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X449454949494549Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:207
Count of miRNA genes:158
Interacting mature miRNAs:179
Transcripts:ENSRNOT00000044009
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 39 39 39 33 17 11
Low 3 43 17 2 18 2 8 11 41 35 24 8
Below cutoff 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000044009   ⟹   ENSRNOP00000043466
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX5,907,266 - 6,011,003 (+)Ensembl
Rnor_6.0 EnsemblX6,430,594 - 6,533,534 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000106616   ⟹   ENSRNOP00000087850
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX5,949,728 - 6,011,003 (+)Ensembl
RefSeq Acc Id: NM_013198   ⟹   NP_037330
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X5,907,327 - 6,010,996 (+)NCBI
Rnor_6.0X6,430,694 - 6,533,520 (+)NCBI
Rnor_5.0X7,249,779 - 7,352,270 (+)NCBI
RGSC_v3.4X17,553,529 - 17,657,852 (+)RGD
CeleraX6,397,919 - 6,500,914 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_037330 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA41566 (Get FASTA)   NCBI Sequence Viewer  
  AAH89814 (Get FASTA)   NCBI Sequence Viewer  
  AAK14225 (Get FASTA)   NCBI Sequence Viewer  
  EDL97664 (Get FASTA)   NCBI Sequence Viewer  
  P19643 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_037330   ⟸   NM_013198
- UniProtKB: P19643 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000043466   ⟸   ENSRNOT00000044009
RefSeq Acc Id: ENSRNOP00000087850   ⟸   ENSRNOT00000106616
Protein Domains
Amino_oxidase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P19643-F1-model_v2 AlphaFold P19643 1-520 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701704
Promoter ID:EPDNEW_R12227
Type:initiation region
Name:Maob_1
Description:monoamine oxidase B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X6,430,684 - 6,430,744EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3041 AgrOrtholog
BioCyc Gene G2FUF-3113 BioCyc
BioCyc Pathway PWY-0 [putrescine degradation III] BioCyc
  PWY-6307 [L-tryptophan degradation X (mammalian, via tryptamine)] BioCyc
  PWY-6313 [serotonin degradation] BioCyc
  PWY-6318 [L-phenylalanine degradation IV (mammalian, via side chain)] BioCyc
  PWY-6342 [noradrenaline and adrenaline degradation] BioCyc
  PWY-6399 [melatonin degradation II] BioCyc
  PWY6666-2 [dopamine degradation] BioCyc
Ensembl Genes ENSRNOG00000029778 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000043466 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000044009 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.50.50.60 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7122068 IMAGE-MGC_LOAD
  IMAGE:7323595 IMAGE-MGC_LOAD
InterPro Amino_oxidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FAD/NAD-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Flavin_amine_oxidase UniProtKB/Swiss-Prot
KEGG Report rno:25750 UniProtKB/Swiss-Prot
MGC_CLONE MGC:108745 IMAGE-MGC_LOAD
  MGC:93583 IMAGE-MGC_LOAD
NCBI Gene 25750 ENTREZGENE
Pfam Amino_oxidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB MAOB RGD
PhenoGen Maob PhenoGen
PRINTS AMINEOXDASEF UniProtKB/Swiss-Prot
Superfamily-SCOP SSF51905 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC228489
UniProt AOFB_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q99PC8_RAT UniProtKB/TrEMBL
UniProt Secondary Q5EBB5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Maob  Monoamine oxidase B      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression abundant in serotonergic neurons and astrocytes 633242