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Gene: Hdac6 (histone deacetylase 6) Rattus norvegicus
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Symbol: Hdac6
Name: histone deacetylase 6
Description: Exhibits deacetylase activity. Involved in several processes, including generation of neurons; regulation of protein modification process; and response to glucocorticoid. Localizes to the axon and centrosome. Predicted to colocalize with the cytoplasmic microtubule and dynein complex. Used to study polycystic kidney disease and polycystic liver disease. Biomarker of hypertension and polycystic liver disease. Orthologous to human HDAC6 (histone deacetylase 6); PARTICIPATES IN histone modification pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: MODEL
Also known as: histone deacetylase 6-like; LOC100911205
Orthologs:
Homo sapiens (human) : HDAC6 (histone deacetylase 6)  HGNC  Alliance
Mus musculus (house mouse) : Hdac6 (histone deacetylase 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hdac6 (histone deacetylase 6)
Pan paniscus (bonobo/pygmy chimpanzee) : HDAC6 (histone deacetylase 6)
Canis lupus familiaris (dog) : HDAC6 (histone deacetylase 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hdac6 (histone deacetylase 6)
Sus scrofa (pig) : HDAC6 (histone deacetylase 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X15,295,372 - 15,316,673 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX15,295,473 - 15,316,671 (+)Ensembl
Rnor_5.0X16,075,029 - 16,096,914 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X26,585,852 - 26,606,999 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X26,658,892 - 26,659,565 (+)NCBI
CeleraX14,635,909 - 14,657,201 (+)NCBICelera
Cytogenetic MapXq12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Hdac6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619981
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.