Tlr7 (toll-like receptor 7) - Rat Genome Database

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Gene: Tlr7 (toll-like receptor 7) Rattus norvegicus
Analyze
Symbol: Tlr7
Name: toll-like receptor 7
RGD ID: 1563357
Description: Predicted to enable RNA binding activity and pattern recognition receptor activity. Predicted to be involved in several processes, including intracellular signal transduction; positive regulation of macromolecule biosynthetic process; and response to virus. Predicted to act upstream of or within positive regulation of macrophage cytokine production and regulation of protein phosphorylation. Predicted to be located in cytoplasmic vesicle; endoplasmic reticulum; and lysosome. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Biomarker of perinatal necrotizing enterocolitis. Human ortholog(s) of this gene implicated in COVID-19 and X-Linked immunodeficiency 74. Orthologous to human TLR7 (toll like receptor 7); PARTICIPATES IN Toll-like receptor signaling pathway; influenza A pathway; measles pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC317468; RGD1563357; similar to toll-like receptor 7
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X30,644,324 - 30,670,796 (+)NCBIGRCr8
mRatBN7.2X27,027,380 - 27,054,309 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX27,027,425 - 27,054,754 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX28,100,702 - 28,126,815 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X31,502,172 - 31,528,275 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X27,715,343 - 27,741,455 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X28,486,836 - 28,513,004 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX28,486,869 - 28,512,957 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X28,882,968 - 28,908,584 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X47,330,737 - 47,356,841 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX27,439,445 - 27,465,491 (+)NCBICelera
Cytogenetic MapXq13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. TLR4 links podocytes with the innate immune system to mediate glomerular injury. Banas MC, etal., J Am Soc Nephrol. 2008 Apr;19(4):704-13. doi: 10.1681/ASN.2007040395. Epub 2008 Feb 6.
2. Differential regulation of Toll-like receptor mRNAs in experimental murine central nervous system infections. Bottcher T, etal., Neurosci Lett. 2003 Jun 19;344(1):17-20.
3. Association of Toll-like receptor 7 variants with life-threatening COVID-19 disease in males: findings from a nested case-control study. Fallerini C, etal., Elife. 2021 Mar 2;10. pii: 67569. doi: 10.7554/eLife.67569.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Combinations of TLR and NOD2 ligands stimulate rat microglial P2X4R expression. Guo LH, etal., Biochem Biophys Res Commun. 2006 Oct 27;349(3):1156-62. Epub 2006 Sep 1.
6. Pathogen recognition by the innate immune system. Kumar H, etal., Int Rev Immunol. 2011 Feb;30(1):16-34.
7. Changes in intestinal Toll-like receptors and cytokines precede histological injury in a rat model of necrotizing enterocolitis. Liu Y, etal., Am J Physiol Gastrointest Liver Physiol. 2009 Sep;297(3):G442-50. Epub 2009 Jul 16.
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. GOA pipeline RGD automated data pipeline
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Critical role of TLR7 in the acceleration of systemic lupus erythematosus in TLR9-deficient mice. Santiago-Raber ML, etal., J Autoimmun. 2010 Jun;34(4):339-48. doi: 10.1016/j.jaut.2009.11.001. Epub 2009 Nov 26.
12. Gene expression of nucleic acid-sensing pattern recognition receptors in children hospitalized for respiratory syncytial virus-associated acute bronchiolitis. Scagnolari C, etal., Clin Vaccine Immunol. 2009 Jun;16(6):816-23. Epub 2009 Apr 22.
13. Mechanistic investigation of immunosuppression in patients with condyloma acuminata. Shi YJ, etal., Mol Med Rep. 2013 Aug;8(2):480-6. doi: 10.3892/mmr.2013.1511. Epub 2013 Jun 6.
14. Differential expression of Toll-like receptor pathway genes in chronic rhinosinusitis with or without nasal polyps. Zhang Q, etal., Acta Otolaryngol. 2013 Feb;133(2):165-73. doi: 10.3109/00016489.2012.717713. Epub 2012 Nov 19.
Additional References at PubMed
PMID:14976261   PMID:14976262   PMID:15723075   PMID:16111635   PMID:16188996   PMID:16286015   PMID:18261938   PMID:18305481   PMID:19593445   PMID:19740627   PMID:21364926   PMID:21753151  
PMID:22765640   PMID:23382219   PMID:24091496   PMID:24740015   PMID:25384124   PMID:26363072   PMID:26434622   PMID:28665028   PMID:31647818   PMID:32682816   PMID:36674770   PMID:37596656  


Genomics

Comparative Map Data
Tlr7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X30,644,324 - 30,670,796 (+)NCBIGRCr8
mRatBN7.2X27,027,380 - 27,054,309 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX27,027,425 - 27,054,754 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX28,100,702 - 28,126,815 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X31,502,172 - 31,528,275 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X27,715,343 - 27,741,455 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X28,486,836 - 28,513,004 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX28,486,869 - 28,512,957 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X28,882,968 - 28,908,584 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X47,330,737 - 47,356,841 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX27,439,445 - 27,465,491 (+)NCBICelera
Cytogenetic MapXq13NCBI
TLR7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X12,867,072 - 12,890,361 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX12,867,072 - 12,890,361 (+)EnsemblGRCh38hg38GRCh38
GRCh37X12,885,191 - 12,908,480 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X12,795,123 - 12,818,401 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X12,644,862 - 12,666,567NCBI
CeleraX16,999,208 - 17,022,486 (+)NCBICelera
Cytogenetic MapXp22.2NCBI
HuRefX10,651,692 - 10,675,129 (+)NCBIHuRef
CHM1_1X12,915,641 - 12,938,921 (+)NCBICHM1_1
T2T-CHM13v2.0X12,448,550 - 12,471,838 (+)NCBIT2T-CHM13v2.0
Tlr7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X166,086,376 - 166,113,570 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX166,087,925 - 166,113,554 (-)EnsemblGRCm39 Ensembl
GRCm38X167,303,380 - 167,330,574 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX167,304,929 - 167,330,558 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X163,742,863 - 163,768,460 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X162,649,036 - 162,674,633 (-)NCBIMGSCv36mm8
CeleraX150,452,330 - 150,504,044 (-)NCBICelera
Cytogenetic MapXF5NCBI
cM MapX78.31NCBI
Tlr7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955544424,850 - 443,564 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955544424,897 - 443,562 (-)NCBIChiLan1.0ChiLan1.0
TLR7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X14,651,418 - 14,674,103 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X14,655,084 - 14,677,769 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X5,479,247 - 5,504,810 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X12,768,698 - 12,790,517 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX12,767,981 - 12,790,517 (+)Ensemblpanpan1.1panPan2
TLR7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X9,331,243 - 9,360,461 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX9,314,815 - 9,359,603 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX9,290,888 - 9,316,297 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X9,283,446 - 9,312,699 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX9,285,506 - 9,311,834 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X9,270,957 - 9,296,384 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X9,310,224 - 9,335,853 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X9,302,542 - 9,328,038 (+)NCBIUU_Cfam_GSD_1.0
Tlr7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X2,593,498 - 2,611,939 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364702,607,508 - 2,610,675 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364702,593,544 - 2,610,972 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TLR7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1X9,573,178 - 9,576,987 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X10,472,850 - 10,476,659 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TLR7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X11,348,520 - 11,372,132 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605613,140,418 - 13,165,724 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tlr7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248821,375,216 - 1,379,705 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tlr7
127 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:71
Count of miRNA genes:60
Interacting mature miRNAs:63
Transcripts:ENSRNOT00000005620
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598873Memor2Memory QTL 22.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)X2099094741052531Rat
70165Bp64Blood pressure QTL 645.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X144812931706553Rat
1298071Edpm12Estrogen-dependent pituitary mass QTL 123.2pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)X292789847927898Rat
2290375Gluco34Glucose level QTL 342.75blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)X2099094741203591Rat
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X143491017Rat
631666Iddm5Insulin dependent diabetes mellitus QTL 5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X449454949494549Rat
10755455Coatc13Coat color QTL 130coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7440600049406000Rat
71116Niddm16Non-insulin dependent diabetes mellitus QTL 167.81blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X1529780260297802Rat

Markers in Region
RH135007  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X27,053,516 - 27,053,729 (+)MAPPERmRatBN7.2
Rnor_6.0X28,512,137 - 28,512,349NCBIRnor6.0
Rnor_5.0X28,908,249 - 28,908,461UniSTSRnor5.0
RGSC_v3.4X47,356,777 - 47,356,989UniSTSRGSC3.4
CeleraX27,465,427 - 27,465,639UniSTS
RH 3.4 MapX345.5UniSTS
Cytogenetic MapXq21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 4 15 2 2
Low 3 31 43 31 4 31 8 8 66 35 31 9 8
Below cutoff 8 10 10 10 3 8 6

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001097582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF032637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730363 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730391 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730396 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730399 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730431 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730451 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730458 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730461 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MT730468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000005620   ⟹   ENSRNOP00000005620
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX27,027,435 - 27,054,754 (+)Ensembl
Rnor_6.0 EnsemblX28,486,869 - 28,512,957 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000104011   ⟹   ENSRNOP00000089883
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX27,027,425 - 27,054,754 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000118923   ⟹   ENSRNOP00000094649
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX27,027,425 - 27,053,850 (+)Ensembl
RefSeq Acc Id: NM_001097582   ⟹   NP_001091051
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X30,644,426 - 30,670,525 (+)NCBI
mRatBN7.2X27,027,483 - 27,053,581 (+)NCBI
Rnor_6.0X28,486,929 - 28,512,201 (+)NCBI
Rnor_5.0X28,882,968 - 28,908,584 (+)NCBI
RGSC_v3.4X47,330,737 - 47,356,841 (+)RGD
CeleraX27,439,445 - 27,465,491 (+)RGD
Sequence:
RefSeq Acc Id: XM_017602079   ⟹   XP_017457568
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X30,644,324 - 30,670,796 (+)NCBI
mRatBN7.2X27,027,380 - 27,054,309 (+)NCBI
Rnor_6.0X28,486,836 - 28,513,004 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017602080   ⟹   XP_017457569
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X30,644,363 - 30,670,796 (+)NCBI
mRatBN7.2X27,027,420 - 27,054,309 (+)NCBI
Rnor_6.0X28,486,836 - 28,513,004 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039099833   ⟹   XP_038955761
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X30,644,363 - 30,670,796 (+)NCBI
mRatBN7.2X27,027,421 - 27,054,309 (+)NCBI
RefSeq Acc Id: XM_039099834   ⟹   XP_038955762
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X30,644,324 - 30,670,796 (+)NCBI
mRatBN7.2X27,027,380 - 27,054,309 (+)NCBI
RefSeq Acc Id: XM_063280082   ⟹   XP_063136152
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X30,644,363 - 30,670,796 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001091051 (Get FASTA)   NCBI Sequence Viewer  
  XP_017457568 (Get FASTA)   NCBI Sequence Viewer  
  XP_017457569 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955761 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955762 (Get FASTA)   NCBI Sequence Viewer  
  XP_063136152 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ABM92443 (Get FASTA)   NCBI Sequence Viewer  
  EDL90569 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000005620.5
  ENSRNOP00000089883.1
  ENSRNOP00000094649.1
GenBank Protein QQJ42888 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42889 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42890 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42891 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42892 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42893 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42894 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42895 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42896 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42897 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42898 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42899 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42900 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42901 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42902 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42903 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42904 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42905 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42906 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42907 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42908 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42909 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42910 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42911 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42912 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42913 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42914 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42915 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42916 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42917 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42918 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42919 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42920 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42921 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42922 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42923 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42924 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42925 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42926 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42927 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42928 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42929 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42930 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42931 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42932 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42933 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42934 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42935 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42936 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42937 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42938 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42939 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42940 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42941 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42942 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42943 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42944 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42945 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42946 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42947 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42948 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42949 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42950 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42951 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42952 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42953 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42954 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42955 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42956 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42957 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42958 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42959 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42960 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42961 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42962 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42963 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42964 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42965 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42966 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42967 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42968 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42969 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42970 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42971 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42972 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42973 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42974 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42975 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42976 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42977 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42978 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42979 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42980 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42981 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42982 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42983 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42984 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42985 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42986 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42987 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42988 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42989 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42990 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42991 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42992 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42993 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42994 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42995 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42996 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42997 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42998 (Get FASTA)   NCBI Sequence Viewer  
  QQJ42999 (Get FASTA)   NCBI Sequence Viewer  
  QQJ43000 (Get FASTA)   NCBI Sequence Viewer  
  QQJ43001 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001091051   ⟸   NM_001097582
- UniProtKB: A5H2Z9 (UniProtKB/TrEMBL),   U5LJA3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017457569   ⟸   XM_017602080
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AM21 (UniProtKB/TrEMBL),   U5LJA3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017457568   ⟸   XM_017602079
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AM21 (UniProtKB/TrEMBL),   U5LJA3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000005620   ⟸   ENSRNOT00000005620
RefSeq Acc Id: XP_038955762   ⟸   XM_039099834
- Peptide Label: isoform X3
- UniProtKB: A0A8I6GHR4 (UniProtKB/TrEMBL),   A6K2G1 (UniProtKB/TrEMBL),   U5LJA3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955761   ⟸   XM_039099833
- Peptide Label: isoform X2
- UniProtKB: A5H2Z9 (UniProtKB/TrEMBL),   U5LJA3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000089883   ⟸   ENSRNOT00000104011
RefSeq Acc Id: ENSRNOP00000094649   ⟸   ENSRNOT00000118923
RefSeq Acc Id: XP_063136152   ⟸   XM_063280082
- Peptide Label: isoform X3
- UniProtKB: U5LJA3 (UniProtKB/TrEMBL),   A0A8I6GHR4 (UniProtKB/TrEMBL),   A6K2G1 (UniProtKB/TrEMBL)
Protein Domains
TIR

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A5H2Z9-F1-model_v2 AlphaFold A5H2Z9 1-1050 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701784
Promoter ID:EPDNEW_R12307
Type:single initiation site
Name:Tlr7_1
Description:toll-like receptor 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X28,486,864 - 28,486,924EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563357 AgrOrtholog
BioCyc Gene G2FUF-2661 BioCyc
Ensembl Genes ENSRNOG00000004249 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000005620.7 UniProtKB/TrEMBL
  ENSRNOT00000104011.1 UniProtKB/TrEMBL
  ENSRNOT00000118923.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.10140 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
InterPro Cys-rich_flank_reg_C UniProtKB/TrEMBL
  L_dom-like UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_12 UniProtKB/TrEMBL
  Toll-Interleukin_rcpt UniProtKB/TrEMBL
  Toll_tir_struct_dom_sf UniProtKB/TrEMBL
KEGG Report rno:317468 UniProtKB/TrEMBL
NCBI Gene 317468 ENTREZGENE
PANTHER PTHR47410:SF2 UniProtKB/TrEMBL
  TOLL-LIKE RECEPTOR 7-RELATED UniProtKB/TrEMBL
Pfam LRR_1 UniProtKB/TrEMBL
  LRR_12 UniProtKB/TrEMBL
  LRR_8 UniProtKB/TrEMBL
  TIR UniProtKB/TrEMBL
PhenoGen Tlr7 PhenoGen
PRINTS INTRLKN1R1F UniProtKB/TrEMBL
  LEURICHRPT UniProtKB/TrEMBL
PROSITE LRR UniProtKB/TrEMBL
  TIR UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004249 RatGTEx
SMART LRR_SD22 UniProtKB/TrEMBL
  LRR_TYP UniProtKB/TrEMBL
  LRRCT UniProtKB/TrEMBL
  TIR UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
  RNI-like UniProtKB/TrEMBL
  TIR UniProtKB/TrEMBL
UniProt A0A8I6AM21 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GHR4 ENTREZGENE, UniProtKB/TrEMBL
  A5H2Z9 ENTREZGENE, UniProtKB/TrEMBL
  A6K2G1 ENTREZGENE, UniProtKB/TrEMBL
  U5LJA3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Tlr7  toll-like receptor 7   Tlr7_predicted  toll-like receptor 7 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Tlr7_predicted  toll-like receptor 7 (predicted)  RGD1563357_predicted  similar to toll-like receptor 7 (predicted)  Symbol and Name updated 1299863 APPROVED
2006-03-07 RGD1563357_predicted  similar to toll-like receptor 7 (predicted)  LOC317468  similar to toll-like receptor 7  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC317468  similar to toll-like receptor 7      Symbol and Name status set to provisional 70820 PROVISIONAL