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Gene: Tlr7 (toll-like receptor 7) Rattus norvegicus
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Symbol: Tlr7
Name: toll-like receptor 7
Description: Exhibits drug binding activity. Involved in microglial cell activation and toll-like receptor signaling pathway. Predicted to localize to several cellular components, including the cytoplasmic vesicle; endoplasmic reticulum; and lysosome. Biomarker of perinatal necrotizing enterocolitis. Orthologous to human TLR7 (toll like receptor 7); PARTICIPATES IN Toll-like receptor signaling pathway; influenza A pathway; measles pathway; INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC317468; RGD1563357; similar to toll-like receptor 7
Orthologs:
Homo sapiens (human) : TLR7 (toll like receptor 7)  HGNC  Alliance
Mus musculus (house mouse) : Tlr7 (toll-like receptor 7)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tlr7 (toll like receptor 7)
Pan paniscus (bonobo/pygmy chimpanzee) : TLR7 (toll like receptor 7)
Canis lupus familiaris (dog) : TLR7 (toll like receptor 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tlr7 (toll like receptor 7)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X28,486,836 - 28,513,004 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX28,486,869 - 28,512,957 (+)Ensembl
Rnor_5.0X28,882,968 - 28,908,584 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X47,330,737 - 47,356,841 (+)NCBIRGSC3.4rn4RGSC3.4
CeleraX27,439,445 - 27,465,491 (+)NCBICelera
Cytogenetic MapXq13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Tlr7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1563357
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.