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Gene: Foxp3 (forkhead box P3) Rattus norvegicus
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Symbol: Foxp3
Name: forkhead box P3
RGD ID: 1562112
Description: Predicted to have several functions, including NFAT protein binding activity; enzyme binding activity; and transcription regulator activity. Involved in establishment of endothelial blood-brain barrier; response to lipopolysaccharide; and response to radiation. Predicted to localize to cytoplasm and nucleoplasm. Used to study intrahepatic cholangiocarcinoma. Biomarker of Korean hemorrhagic fever; asthma; bronchiolitis obliterans; hypertension; and hypothyroidism. Human ortholog(s) of this gene implicated in colorectal cancer; immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome; pulmonary tuberculosis; and type 1 diabetes mellitus. Orthologous to human FOXP3 (forkhead box P3); INTERACTS WITH 1-naphthyl isothiocyanate; amphetamine; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: forkhead box protein P3; LOC317382; RGD1562112; similar to scurfin
Orthologs:
Homo sapiens (human) : FOXP3 (forkhead box P3)  HGNC  Alliance
Mus musculus (house mouse) : Foxp3 (forkhead box P3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Foxp3 (forkhead box P3)
Pan paniscus (bonobo/pygmy chimpanzee) : FOXP3 (forkhead box P3)
Canis lupus familiaris (dog) : FOXP3 (forkhead box P3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Foxp3 (forkhead box P3)
Sus scrofa (pig) : FOXP3 (forkhead box P3)
Chlorocebus sabaeus (African green monkey) : FOXP3 (forkhead box P3)
Heterocephalus glaber (naked mole-rat) : Foxp3 (forkhead box P3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X15,753,175 - 15,768,648 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX15,753,175 - 15,768,522 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X16,544,710 - 16,565,562 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X26,950,006 - 26,965,329 (-)NCBIRGSC3.4rn4RGSC3.4
CeleraX14,991,861 - 15,007,179 (-)NCBICelera
Cytogenetic MapXq12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Foxp3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1562112
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-11-17
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.