Foxp3 (forkhead box P3) - Rat Genome Database

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Gene: Foxp3 (forkhead box P3) Rattus norvegicus
Analyze
Symbol: Foxp3
Name: forkhead box P3
RGD ID: 1562112
Description: Predicted to enable several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; NFAT protein binding activity; and enzyme binding activity. Involved in several processes, including establishment of endothelial blood-brain barrier; negative regulation of defense response to virus; and response to rapamycin. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be active in nucleus. Used to study intrahepatic cholangiocarcinoma. Biomarker of Korean hemorrhagic fever; asthma; bronchiolitis obliterans; hypertension; and hypothyroidism. Human ortholog(s) of this gene implicated in Human papillomavirus infectious disease; colorectal cancer; immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome; pulmonary tuberculosis; and type 1 diabetes mellitus. Orthologous to human FOXP3 (forkhead box P3); INTERACTS WITH 1-naphthyl isothiocyanate; amphetamine; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: forkhead box protein P3; LOC317382; RGD1562112; similar to scurfin
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X14,908,494 - 14,924,994 (-)NCBImRatBN7.2
mRatBN7.2 EnsemblX14,908,494 - 14,923,838 (-)Ensembl
Rnor_6.0X15,753,175 - 15,768,648 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX15,753,175 - 15,768,522 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X16,544,710 - 16,565,562 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X26,950,006 - 26,965,329 (-)NCBIRGSC3.4rn4RGSC3.4
CeleraX14,991,861 - 15,007,179 (-)NCBICelera
Cytogenetic MapXq12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute-On-Chronic Liver Failure  (ISO)
adult T-cell leukemia  (ISO)
Airway Remodeling  (ISO)
allergic disease  (ISO)
anemia  (ISO)
Animal Toxoplasmosis  (ISO)
anogenital venereal wart  (ISO)
asthma  (IEP,ISO)
autistic disorder  (ISO)
bacterial pneumonia  (ISO)
Breast Neoplasms  (ISO)
bronchiolitis obliterans  (IEP)
cervical squamous cell carcinoma  (ISO)
chlamydia  (ISO)
Chronic Hepatitis B  (ISO)
Chronic Hepatitis C  (ISO)
colorectal cancer  (ISO)
congenital disorder of glycosylation type IIm  (ISO)
cutaneous leishmaniasis  (ISO)
dermatitis  (ISO)
diabetes mellitus  (ISO)
Dysbiosis  (IEP)
endometriosis  (ISO)
Endotoxemia  (IEP)
Epstein-Barr Virus Infections  (ISO)
Experimental Arthritis  (IEP)
Experimental Autoimmune Myocarditis  (IEP)
Experimental Autoimmune Neuritis  (IEP)
Experimental Colitis  (IDA,ISO)
Experimental Diabetes Mellitus  (IEP)
genetic disease  (ISO)
Graft vs Host Disease  (IEP)
hepatitis B  (ISO)
hepatitis C  (ISO)
hepatocellular carcinoma  (ISO)
Hydranencephaly with Renal Aplasia-Dysplasia  (ISO)
Hydrops Fetalis  (ISO)
hypertension  (IEP)
hypothyroidism  (IEP)
immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome  (ISO)
infectious mononucleosis  (ISO)
intrahepatic cholangiocarcinoma  (IDA)
Korean hemorrhagic fever  (IEP)
Lung Injury  (ISO)
malaria  (ISO)
multidrug-resistant tuberculosis  (ISO)
Neuralgia  (IEP,ISO)
neurodegeneration with brain iron accumulation 5  (ISO)
occupational dermatitis  (ISO)
papillomavirus infectious disease  (ISO)
pleural tuberculosis  (ISO)
polycystic ovary syndrome  (ISO)
primary biliary cholangitis  (ISO)
pulmonary tuberculosis  (ISO)
Recurrent Respiratory Papillomatosis  (ISO)
rheumatoid arthritis  (ISO)
Sepsis  (ISO)
spermatogenic failure 3  (ISO)
Spinal Cord Injuries  (IEP)
Squamous Intraepithelial Lesions of the Cervix  (ISO)
syndromic X-linked intellectual disability Lubs type  (ISO)
syphilis  (ISO)
Transplant Rejection  (ISO)
tropical spastic paraparesis  (ISO)
type 1 diabetes mellitus  (ISO)
vaccinia  (ISO)
Wiskott-Aldrich syndrome  (ISS)
Wound Infection  (IEP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(+)-Tetrandrine  (ISO)
(R)-mevalonic acid  (ISO)
(S)-nicotine  (ISO)
1-Hydroxypyrene  (ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-azacytidine  (ISO)
aflatoxin B1  (ISO)
alloxan  (ISO)
alpha-naphthoflavone  (ISO)
amiodarone  (ISO)
amphetamine  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzalkonium chloride  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bleomycin A2  (ISO)
calcitriol  (ISO)
carbon monoxide  (ISO)
carbon nanotube  (ISO)
chloroquine  (ISO)
chlorpyrifos  (ISO)
cyclophosphamide  (ISO)
deoxynivalenol  (ISO)
dextran sulfate  (EXP,ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
dorsomorphin  (ISO)
fingolimod hydrochloride  (ISO)
fragrance  (ISO)
fulvestrant  (ISO)
fumonisin B1  (ISO)
hydralazine  (ISO)
lead diacetate  (EXP,ISO)
lead(0)  (ISO)
lead(2+)  (ISO)
leflunomide  (ISO)
levamisole  (ISO)
lipopolysaccharide  (ISO)
methimazole  (EXP)
N-acetyl-L-cysteine  (ISO)
nickel atom  (ISO)
nicotine  (ISO)
nitrogen dioxide  (ISO)
obeticholic acid  (ISO)
ozone  (ISO)
phenanthrene  (EXP)
phenytoin  (ISO)
platycodin D  (ISO)
procainamide  (ISO)
progesterone  (ISO)
quinacrine  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP,ISO)
silicon dioxide  (ISO)
simvastatin  (EXP,ISO)
sirolimus  (ISO)
sodium arsenite  (ISO)
tamibarotene  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
toluene  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
Triptolide  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
zidovudine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
B cell homeostasis  (ISO)
CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation  (ISO)
establishment of endothelial blood-brain barrier  (IEP)
gene expression  (ISO)
myeloid cell homeostasis  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of chronic inflammatory response  (ISO)
negative regulation of CREB transcription factor activity  (ISO)
negative regulation of cytokine production  (ISO)
negative regulation of defense response to virus  (IMP)
negative regulation of DNA-binding transcription factor activity  (ISO)
negative regulation of gene expression  (ISO)
negative regulation of histone acetylation  (ISO)
negative regulation of histone deacetylation  (ISO)
negative regulation of immune response  (ISO)
negative regulation of inflammatory response  (ISO)
negative regulation of interferon-gamma production  (ISO)
negative regulation of interleukin-10 production  (ISO)
negative regulation of interleukin-17 production  (ISO)
negative regulation of interleukin-2 production  (ISO)
negative regulation of interleukin-4 production  (ISO)
negative regulation of interleukin-5 production  (ISO)
negative regulation of interleukin-6 production  (ISO)
negative regulation of isotype switching to IgE isotypes  (ISO)
negative regulation of lymphocyte proliferation  (ISO)
negative regulation of NF-kappaB transcription factor activity  (ISO)
negative regulation of T cell cytokine production  (ISO)
negative regulation of T cell proliferation  (ISO)
negative regulation of T-helper 17 cell differentiation  (ISO)
negative regulation of transcription by RNA polymerase II  (IBA,ISO)
negative regulation of transcription, DNA-templated  (ISO)
negative regulation of tumor necrosis factor production  (ISO)
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of histone acetylation  (ISO)
positive regulation of immature T cell proliferation in thymus  (ISO)
positive regulation of interleukin-4 production  (ISO)
positive regulation of peripheral T cell tolerance induction  (ISO)
positive regulation of regulatory T cell differentiation  (ISO)
positive regulation of T cell anergy  (ISO)
positive regulation of T cell tolerance induction  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of transcription, DNA-templated  (ISO)
positive regulation of transforming growth factor beta1 production  (ISO)
regulation of immunoglobulin production  (ISO)
regulation of isotype switching to IgG isotypes  (ISO)
regulation of T cell anergy  (ISO)
regulation of transcription by RNA polymerase II  (IBA,ISO)
response to lipopolysaccharide  (IEP)
response to radiation  (IEP)
response to rapamycin  (IEP)
response to virus  (ISO)
T cell activation  (ISO)
T cell mediated immunity  (ISO)
T cell receptor signaling pathway  (ISO)
tolerance induction  (ISO)
tolerance induction to self antigen  (ISO)

Cellular Component
cellular_component  (ND)
cytoplasm  (ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,ISO)

References

References - curated
1. Amador CA, etal., Hypertension. 2014 Apr;63(4):797-803. doi: 10.1161/HYPERTENSIONAHA.113.02883. Epub 2014 Jan 13.
2. Asada M, etal., Exp Dermatol. 2012 Feb;21(2):118-22. doi: 10.1111/j.1600-0625.2011.01404.x. Epub 2011 Dec 6.
3. Beiranvand E, etal., BMC Infect Dis. 2017 Oct 11;17(1):673. doi: 10.1186/s12879-017-2762-5.
4. Cezar-Dos-Santos F, etal., J Cancer Res Clin Oncol. 2019 Aug;145(8):2013-2025. doi: 10.1007/s00432-019-02951-x. Epub 2019 Jun 8.
5. Chen S, etal., Reprod Biol Endocrinol. 2012 Apr 27;10:34. doi: 10.1186/1477-7827-10-34.
6. Corradi-Perini C, etal., Transplant Proc. 2017 May;49(4):902-905. doi: 10.1016/j.transproceed.2017.01.064.
7. Demirkiran A, etal., Transplantation. 2007 Mar 27;83(6):819-23. doi: 10.1097/01.tp.0000258597.97468.88.
8. Ding FM, etal., Exp Lung Res. 2015 Feb;41(1):44-55. doi: 10.3109/01902148.2014.964351. Epub 2014 Nov 14.
9. Easterbrook JD, etal., Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15502-7. Epub 2007 Sep 18.
10. Eijkelkamp N, etal., Gut. 2007 Jun;56(6):847-54. doi: 10.1136/gut.2006.107094. Epub 2007 Jan 17.
11. Finney OC, etal., Eur J Immunol. 2009 May;39(5):1288-300. doi: 10.1002/eji.200839112.
12. Freyschmidt EJ, etal., J Immunol. 2010 Jul 15;185(2):1295-302. doi: 10.4049/jimmunol.0903144. Epub 2010 Jun 14.
13. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
14. Ghezeldasht SA, etal., Appl Biochem Biotechnol. 2017 Aug;182(4):1403-1414. doi: 10.1007/s12010-017-2406-7. Epub 2017 Jan 18.
15. He Y, etal., Biosci Rep. 2018 Nov 7;38(6). pii: BSR20180895. doi: 10.1042/BSR20180895. Print 2018 Dec 21.
16. Hwang JH, etal., Exp Ther Med. 2018 Jul;16(1):310-320. doi: 10.3892/etm.2018.6190. Epub 2018 May 18.
17. Jiao H and Ren H, Drug Des Devel Ther. 2018 Nov 6;12:3817-3824. doi: 10.2147/DDDT.S175331. eCollection 2018.
18. Jungraithmayr W, etal., Eur Respir J. 2010 Jun;35(6):1354-63. Epub 2009 Oct 19.
19. Karube K, etal., Mod Pathol. 2008 May;21(5):617-25. doi: 10.1038/modpathol.2008.25. Epub 2008 Feb 8.
20. Kwon TK, etal., J Otolaryngol Head Neck Surg. 2017 Mar 15;46(1):21. doi: 10.1186/s40463-017-0197-z.
21. Li J, etal., Inflammation. 2015;38(3):995-1002. doi: 10.1007/s10753-014-0063-3.
22. Li Y, etal., Mol Med Rep. 2017 Dec;16(6):8137-8145. doi: 10.3892/mmr.2017.7605. Epub 2017 Sep 25.
23. Liang CL and Wang J, Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2008 Mar;24(3):270-3.
24. Liu C, etal., World J Gastroenterol. 2009 Dec 14;15(46):5843-50. doi: 10.3748/wjg.15.5843.
25. Liu YW, etal., Benef Microbes. 2016 Jun;7(3):387-96. doi: 10.3920/BM2015.0109. Epub 2016 Mar 1.
26. Mahdavinejad L, etal., J Interferon Cytokine Res. 2018 Oct;38(10):457-462. doi: 10.1089/jir.2018.0048.
27. Miyaaki H, etal., Liver Int. 2009 May;29(5):702-7. doi: 10.1111/j.1478-3231.2008.01842.x. Epub 2008 Jul 30.
28. Nabavi NS, etal., Parasite Immunol. 2018 Jan;40(1). doi: 10.1111/pim.12507. Epub 2017 Dec 17.
29. OMIM Disease Annotation Pipeline
30. Park S, etal., Exp Mol Med. 2016 Sep 16;48(9):e259. doi: 10.1038/emm.2016.83.
31. Putilin DA, etal., J Med Life. 2020 Jan-Mar;13(1):50-55. doi: 10.25122/jml-2020-0029.
32. Ramirez E, etal., Braz J Med Biol Res. 2010 Nov;43(11):1109-15. doi: 10.1590/s0100-879x2010007500107. Epub 2010 Oct 8.
33. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
34. RGD automated import pipeline for gene-chemical interactions
35. RGD comprehensive gene curation
36. Rivas MN, etal., J Clin Invest. 2012 May;122(5):1933-47. doi: 10.1172/JCI40591. Epub 2012 Apr 2.
37. Sasaki M, etal., J Clin Pathol. 2007 Oct;60(10):1102-7. doi: 10.1136/jcp.2006.044776. Epub 2006 Dec 8.
38. Schultze FC, etal., Clin Biochem. 2014 Feb;47(3):201-5. doi: 10.1016/j.clinbiochem.2013.11.013. Epub 2013 Nov 26.
39. Shen HB, etal., Chin J Integr Med. 2018 Apr;24(4):278-283. doi: 10.1007/s11655-017-2792-2. Epub 2017 Dec 21.
40. Shi YJ, etal., Mol Med Rep. 2013 Aug;8(2):480-6. doi: 10.3892/mmr.2013.1511. Epub 2013 Jun 6.
41. Shin J, etal., Nanomedicine. 2019 Jun;18:90-100. doi: 10.1016/j.nano.2019.02.023. Epub 2019 Mar 8.
42. Sun Z, etal., J Tradit Chin Med. 2020 Feb;40(1):38-48.
43. Toossi Z, etal., Clin Exp Immunol. 2011 Mar;163(3):333-8. doi: 10.1111/j.1365-2249.2010.04269.x.
44. Walther M, etal., Immunity. 2005 Sep;23(3):287-96. doi: 10.1016/j.immuni.2005.08.006.
45. Wan L, etal., Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2013 Mar;29(3):251-5.
46. Wang C, etal., Transpl Immunol. 2011 Apr 15;24(3):149-56. doi: 10.1016/j.trim.2010.12.004. Epub 2011 Jan 1.
47. Wang Q, etal., BMC Immunol. 2011 Apr 14;12:25. doi: 10.1186/1471-2172-12-25.
48. Wang Q, etal., Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2013 Apr;21(2):469-73. doi: 10.7534/j.issn.1009-2137.2013.02.044.
49. Wang S, etal., Cardiology. 2010;115(2):107-13. doi: 10.1159/000256660. Epub 2009 Nov 10.
50. Wang WH, etal., World J Gastroenterol. 2010 Nov 21;16(43):5502-9. doi: 10.3748/wjg.v16.i43.5502.
51. Wildin RS, etal., Nat Genet. 2001 Jan;27(1):18-20.
52. Wu YE, etal., Mol Med Rep. 2015 Apr;11(4):3134-42. doi: 10.3892/mmr.2014.3033. Epub 2014 Dec 3.
53. Xia X, etal., Liver Transpl. 2012 Jun;18(6):696-706. doi: 10.1002/lt.23414.
54. Yan XB, etal., Rev Neurol (Paris). 2019 Jun;175(6):396-402. doi: 10.1016/j.neurol.2018.12.006. Epub 2019 Apr 23.
55. Yang J and Xu L, Med Sci Monit. 2016 Aug 8;22:2785-92. doi: 10.12659/msm.896827.
56. Yao J, etal., Am J Surg Pathol. 2013 Sep;37(9):1407-12. doi: 10.1097/PAS.0b013e31828f2322.
57. Zhang CH, etal., Asian Pac J Trop Med. 2014 Apr;7(4):305-8. doi: 10.1016/S1995-7645(14)60044-4.
58. Zhang H, etal., Am J Reprod Immunol. 2012 Feb;67(2):112-21. doi: 10.1111/j.1600-0897.2011.01065.x. Epub 2011 Sep 19.
59. Zhang M, etal., Microb Pathog. 2017 Sep;110:426-430. doi: 10.1016/j.micpath.2017.07.029. Epub 2017 Jul 18.
60. Zhao J, etal., Exp Ther Med. 2016 Jun;11(6):2300-2304. doi: 10.3892/etm.2016.3178. Epub 2016 Mar 23.
61. Zhao M, etal., Virol J. 2017 Jan 13;14(1):5. doi: 10.1186/s12985-016-0670-8.
62. Zheng Z, etal., Immunology. 2018 Feb;153(2):246-252. doi: 10.1111/imm.12837. Epub 2017 Oct 16.
63. Ziklo N, etal., BMC Infect Dis. 2019 Mar 4;19(1):218. doi: 10.1186/s12879-019-3843-4.
Additional References at PubMed
PMID:7930593   PMID:8566060   PMID:10072494   PMID:11265635   PMID:11483607   PMID:11714795   PMID:12522256   PMID:12612578   PMID:15100250   PMID:15466453   PMID:15652505   PMID:15780990  
PMID:15790681   PMID:15809349   PMID:16203996   PMID:16227984   PMID:16230479   PMID:16275384   PMID:16301745   PMID:16532000   PMID:16652169   PMID:16769892   PMID:16873067   PMID:16920951  
PMID:16945588   PMID:17028180   PMID:17360565   PMID:17377532   PMID:18368049   PMID:18573908   PMID:18665051   PMID:18997793   PMID:19015308   PMID:19100737   PMID:19276356   PMID:19956764  
PMID:20583921   PMID:20706986   PMID:20944002   PMID:20979845   PMID:21304439   PMID:21458306   PMID:21948080   PMID:22079196   PMID:22564625   PMID:22588919   PMID:22678915   PMID:23169781  
PMID:24012345   PMID:24501220   PMID:25001933   PMID:25066760   PMID:25598450   PMID:26684623   PMID:28396406   PMID:28469165   PMID:31314754   PMID:32599120  


Genomics

Comparative Map Data
Foxp3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X14,908,494 - 14,924,994 (-)NCBImRatBN7.2
mRatBN7.2 EnsemblX14,908,494 - 14,923,838 (-)Ensembl
Rnor_6.0X15,753,175 - 15,768,648 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX15,753,175 - 15,768,522 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X16,544,710 - 16,565,562 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X26,950,006 - 26,965,329 (-)NCBIRGSC3.4rn4RGSC3.4
CeleraX14,991,861 - 15,007,179 (-)NCBICelera
Cytogenetic MapXq12NCBI
FOXP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX49,250,438 - 49,270,477 (-)EnsemblGRCh38hg38GRCh38
GRCh38X49,250,436 - 49,264,932 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X49,106,899 - 49,121,172 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X48,994,354 - 49,008,232 (-)NCBINCBI36hg18NCBI36
Build 34X48,863,780 - 48,877,659NCBI
CeleraX52,543,105 - 52,557,472 (+)NCBI
Cytogenetic MapXp11.23NCBI
HuRefX46,763,332 - 46,777,541 (-)NCBIHuRef
CHM1_1X49,139,199 - 49,153,588 (-)NCBICHM1_1
Foxp3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X7,445,915 - 7,461,482 (+)NCBIGRCm39mm39
GRCm39 EnsemblX7,439,883 - 7,461,484 (+)Ensembl
GRCm38X7,579,676 - 7,595,243 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX7,573,644 - 7,595,245 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X7,156,819 - 7,172,360 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X6,736,652 - 6,752,193 (+)NCBImm8
CeleraX3,876,537 - 3,892,077 (-)NCBICelera
Cytogenetic MapXA1.1NCBI
cM MapX3.41NCBI
Foxp3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955543731,707 - 742,606 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955543731,707 - 742,606 (-)NCBIChiLan1.0ChiLan1.0
FOXP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X49,402,652 - 49,417,029 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX49,402,652 - 49,417,029 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X41,550,462 - 41,567,492 (-)NCBIMhudiblu_PPA_v0panPan3
FOXP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X42,331,229 - 42,362,841 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX42,344,108 - 42,350,758 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX16,722,772 - 16,729,421 (-)NCBI
ROS_Cfam_1.0X42,484,818 - 42,504,672 (-)NCBI
UMICH_Zoey_3.1X42,469,693 - 42,476,343 (-)NCBI
UNSW_CanFamBas_1.0X42,457,152 - 42,463,801 (-)NCBI
UU_Cfam_GSD_1.0X42,552,106 - 42,558,755 (-)NCBI
Foxp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X34,877,987 - 34,897,169 (-)NCBI
SpeTri2.0NW_0049367211,118,376 - 1,125,282 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FOXP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX43,303,782 - 43,328,735 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X43,303,777 - 43,328,164 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X48,151,901 - 48,175,580 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FOXP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X46,349,890 - 46,365,133 (-)NCBI
Vero_WHO_p1.0NW_02366607611,912,136 - 11,927,083 (-)NCBI
Foxp3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624893995,145 - 1,008,492 (-)NCBI

Position Markers
RH136802  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X14,909,682 - 14,909,827 (+)MAPPERmRatBN7.2
Rnor_6.0X15,754,364 - 15,754,508NCBIRnor6.0
Rnor_5.0X16,545,899 - 16,546,043UniSTSRnor5.0
RGSC_v3.4X26,951,195 - 26,951,339UniSTSRGSC3.4
CeleraX14,993,050 - 14,993,194UniSTS
RH 3.4 MapX167.4UniSTS
Cytogenetic MapXq13UniSTS
BG380640  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X14,911,941 - 14,912,081 (+)MAPPERmRatBN7.2
Rnor_6.0X15,756,623 - 15,756,762NCBIRnor6.0
Rnor_5.0X16,548,158 - 16,548,297UniSTSRnor5.0
RGSC_v3.4X26,953,454 - 26,953,593UniSTSRGSC3.4
CeleraX14,995,309 - 14,995,448UniSTS
RH 3.4 MapX166.6UniSTS
Cytogenetic MapXq13UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X143491017Rat
634325Bw13Body weight QTL 130body mass (VT:0001259)body weight (CMO:0000012)X144797220991088Rat
70165Bp64Blood pressure QTL 645.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X144812931706553Rat
631204Gluco15Glucose level QTL 150.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)X162371522646544Rat
1298071Edpm12Estrogen-dependent pituitary mass QTL 123.2pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)X292789847927898Rat
10755455Coatc13Coat color QTL 130coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7440600049406000Rat
631666Iddm5Insulin dependent diabetes mellitus QTL 5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X449454949494549Rat
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:560
Count of miRNA genes:275
Interacting mature miRNAs:359
Transcripts:ENSRNOT00000015641
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 2 9 17 1 19 1 8 11 12 8 14 11 8
Below cutoff 1 24 23 23 23 62 23 23

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000015641   ⟹   ENSRNOP00000015641
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX14,908,494 - 14,917,167 (-)Ensembl
Rnor_6.0 EnsemblX15,753,175 - 15,761,932 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000077391   ⟹   ENSRNOP00000073801
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX14,910,646 - 14,923,838 (-)Ensembl
Rnor_6.0 EnsemblX15,755,327 - 15,768,522 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000091146   ⟹   ENSRNOP00000071307
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX14,910,646 - 14,917,193 (-)Ensembl
Rnor_6.0 EnsemblX15,755,327 - 15,761,932 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000098091   ⟹   ENSRNOP00000080390
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX14,910,646 - 14,923,838 (-)Ensembl
RefSeq Acc Id: NM_001108250   ⟹   NP_001101720
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X14,908,494 - 14,923,814 (-)NCBI
Rnor_6.0X15,753,175 - 15,768,498 (-)NCBI
Rnor_5.0X16,544,710 - 16,565,562 (-)NCBI
RGSC_v3.4X26,950,006 - 26,965,329 (-)RGD
CeleraX14,991,861 - 15,007,179 (-)RGD
Sequence:
RefSeq Acc Id: XM_039099794   ⟹   XP_038955722
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X14,909,846 - 14,917,495 (-)NCBI
RefSeq Acc Id: XM_039099795   ⟹   XP_038955723
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X14,910,704 - 14,917,495 (-)NCBI
RefSeq Acc Id: XR_005497985
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X14,909,846 - 14,924,994 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001101720   ⟸   NM_001108250
- UniProtKB: D3ZKI1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000073801   ⟸   ENSRNOT00000077391
RefSeq Acc Id: ENSRNOP00000071307   ⟸   ENSRNOT00000091146
RefSeq Acc Id: ENSRNOP00000015641   ⟸   ENSRNOT00000015641
RefSeq Acc Id: XP_038955722   ⟸   XM_039099794
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038955723   ⟸   XM_039099795
- Peptide Label: isoform X2
RefSeq Acc Id: ENSRNOP00000080390   ⟸   ENSRNOT00000098091
Protein Domains
C2H2-type   Fork-head

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701753
Promoter ID:EPDNEW_R12274
Type:single initiation site
Name:Foxp3_1
Description:forkhead box P3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X15,768,517 - 15,768,577EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BUF/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
DA/OlaHsd (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
F344/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FXLE16/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/FarMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrcAek (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
M520/NRrrcMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MWF/Hsd (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/OlalpcvMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/RijCrl (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (2019)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (2020)
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Sequenced By: MCW
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562112 AgrOrtholog
Ensembl Genes ENSRNOG00000011702 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000015641 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000071307 UniProtKB/TrEMBL
  ENSRNOP00000073801 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000015641 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000077391 UniProtKB/TrEMBL
  ENSRNOT00000091146 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
InterPro FOXP-CC UniProtKB/TrEMBL
  TF_fork_head UniProtKB/TrEMBL
  TF_fork_head_CS_2 UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
  Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
KEGG Report rno:317382 UniProtKB/TrEMBL
NCBI Gene 317382 ENTREZGENE
Pfam Fork_head UniProtKB/TrEMBL
  FOXP-CC UniProtKB/TrEMBL
PhenoGen Foxp3 PhenoGen
PRINTS FORKHEAD UniProtKB/TrEMBL
PROSITE FORK_HEAD_2 UniProtKB/TrEMBL
  FORK_HEAD_3 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
SMART SM00339 UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
UniProt D3ZKI1 ENTREZGENE, UniProtKB/TrEMBL
  D4Q8I2_RAT UniProtKB/TrEMBL
  D4Q8I3_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Foxp3  forkhead box P3   Foxp3_predicted  forkhead box P3 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Foxp3_predicted  forkhead box P3 (predicted)  RGD1562112_predicted  similar to scurfin (predicted)  Symbol and Name updated 1299863 APPROVED
2006-03-07 RGD1562112_predicted  similar to scurfin (predicted)  LOC317382  similar to scurfin  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC317382  similar to scurfin      Symbol and Name status set to provisional 70820 PROVISIONAL