Huwe1 (HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1) - Rat Genome Database
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Gene: Huwe1 (HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1) Rattus norvegicus
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Symbol: Huwe1
Name: HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
RGD ID: 1561763
Description: Exhibits DNA binding activity. Predicted to be involved in several processes, including positive regulation of protein metabolic process; protein ubiquitination; and regulation of mitochondrion organization. Localizes to nucleus. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Turner type. Orthologous to human HUWE1 (HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1); PARTICIPATES IN p53 signaling pathway; INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A; flutamide.
Type: gene
RefSeq Status: MODEL
Also known as: HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase; hypothetical protein LOC501546; LOC501546
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X20,871,278 - 21,001,378 (+)NCBI
Rnor_6.0 EnsemblX21,499,934 - 21,598,876 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X21,474,627 - 21,603,348 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X23,634,031 - 23,635,008 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0X21,848,515 - 21,950,709 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X41,269,837 - 41,397,687 (+)NCBIRGSC3.4rn4RGSC3.4
CeleraX21,152,936 - 21,282,567 (+)NCBICelera
Cytogenetic MapXq13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,ISO,ISS)
cytosol  (IEA,ISO)
Golgi membrane  (IBA)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IDA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:7478539   PMID:15767685   PMID:15989957   PMID:19028597   PMID:19056867   PMID:19713937   PMID:19946888   PMID:20534529   PMID:22658674   PMID:24270810   PMID:26214738   PMID:26698301  
PMID:30217973   PMID:30221657  


Genomics

Comparative Map Data
Huwe1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X20,871,278 - 21,001,378 (+)NCBI
Rnor_6.0 EnsemblX21,499,934 - 21,598,876 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X21,474,627 - 21,603,348 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X23,634,031 - 23,635,008 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0X21,848,515 - 21,950,709 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X41,269,837 - 41,397,687 (+)NCBIRGSC3.4rn4RGSC3.4
CeleraX21,152,936 - 21,282,567 (+)NCBICelera
Cytogenetic MapXq13NCBI
HUWE1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX53,532,096 - 53,686,728 (-)EnsemblGRCh38hg38GRCh38
GRCh38X53,532,096 - 53,686,723 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X53,559,057 - 53,713,697 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh37X53,559,057 - 53,713,664 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X53,576,476 - 53,697,776 (-)NCBINCBI36hg18NCBI36
CeleraX57,390,630 - 57,545,232 (-)NCBI
Cytogenetic MapXp11.22NCBI
HuRefX50,615,901 - 50,769,910 (-)NCBIHuRef
CHM1_1X53,550,037 - 53,704,948 (-)NCBICHM1_1
Huwe1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X150,583,779 - 150,718,413 (+)NCBIGRCm39mm39
GRCm38X151,800,785 - 151,935,417 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX151,800,807 - 151,935,417 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X148,237,825 - 148,369,960 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X147,144,043 - 147,275,608 (+)NCBImm8
CeleraX132,494,924 - 132,629,529 (-)NCBICelera
Cytogenetic MapXF3NCBI
Huwe1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955475551,159 - 671,747 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955475550,643 - 671,771 (-)NCBIChiLan1.0ChiLan1.0
HUWE1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X53,855,404 - 54,005,383 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX53,855,404 - 54,005,366 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X45,746,228 - 45,897,250 (-)NCBIMhudiblu_PPA_v0panPan3
HUWE1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 EnsemblX45,234,322 - 45,410,043 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1X45,234,666 - 45,409,641 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Huwe1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936751478,978 - 622,818 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HUWE1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX46,282,415 - 46,441,623 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X46,281,958 - 46,444,315 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X51,780,471 - 51,942,782 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HUWE1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X49,661,506 - 49,814,551 (-)NCBI
ChlSab1.1 EnsemblX49,660,790 - 49,808,572 (-)Ensembl
Huwe1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624909745,141 - 891,421 (-)NCBI

Position Markers
DXRat8  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0X21,592,623 - 21,592,783NCBIRnor6.0
Rnor_5.0X21,859,080 - 21,859,240UniSTSRnor5.0
RGSC_v3.4X41,386,788 - 41,387,080RGDRGSC3.4
RGSC_v3.4X41,386,879 - 41,387,039UniSTSRGSC3.4
RGSC_v3.1X41,440,348 - 41,440,508RGD
CeleraX21,272,130 - 21,272,290UniSTS
RH 3.4 MapX186.31UniSTS
RH 3.4 MapX186.31RGD
RH 2.0 Map21223.4RGD
SHRSP x BN MapX6.8999RGD
FHH x ACI MapX7.93RGD
Cytogenetic MapXq21UniSTS
AU046935  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0X21,592,648 - 21,592,888NCBIRnor6.0
Rnor_5.0X21,858,975 - 21,859,215UniSTSRnor5.0
RGSC_v3.4X41,386,904 - 41,387,144UniSTSRGSC3.4
CeleraX21,272,155 - 21,272,395UniSTS
Cytogenetic MapXq21UniSTS
RH142513  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0X21,539,418 - 21,539,645NCBIRnor6.0
Rnor_5.0X21,910,974 - 21,911,201UniSTSRnor5.0
RGSC_v3.4X41,335,217 - 41,335,444UniSTSRGSC3.4
CeleraX21,220,268 - 21,220,495UniSTS
Cytogenetic MapXq21UniSTS
AU048657  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0X21,511,228 - 21,511,473NCBIRnor6.0
Rnor_5.0X21,939,146 - 21,939,391UniSTSRnor5.0
RGSC_v3.4X41,306,598 - 41,306,843UniSTSRGSC3.4
CeleraX21,191,983 - 21,192,228UniSTS
Cytogenetic MapXq21UniSTS
MARC_15341-15342:1017678837:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0X21,592,466 - 21,593,358NCBIRnor6.0
Rnor_5.0X21,858,505 - 21,859,397UniSTSRnor5.0
RGSC_v3.4X41,386,722 - 41,387,614UniSTSRGSC3.4
CeleraX21,271,973 - 21,272,865UniSTS
Cytogenetic MapXq21UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X144092703Rat
634325Bw13Body weight QTL 130body mass (VT:0001259)body weight (CMO:0000012)X166245321592783Rat
70165Bp64Blood pressure QTL 645.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X166260933443848Rat
631204Gluco15Glucose level QTL 150.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)X183816624331837Rat
1298071Edpm12Estrogen-dependent pituitary mass QTL 123.2pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)X428214049282140Rat
631666Iddm5Insulin dependent diabetes mellitus QTL 5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X595407850954078Rat
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X15688119127888215Rat
71116Niddm16Non-insulin dependent diabetes mellitus QTL 167.81blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X1815335263153352Rat
1598873Memor2Memory QTL 22.5exploratory behavior trait (VT:0010471)average horizontal distance in proximity to the target during voluntary locomotion in an experimental apparatus (CMO:0002674)X2159262344320739Rat
2290375Gluco34Glucose level QTL 342.75blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)X2159262344468300Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:271
Count of miRNA genes:170
Interacting mature miRNAs:206
Transcripts:ENSRNOT00000003882, ENSRNOT00000004064
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 42 55 39 19 39 8 11 74 35 40 11 8
Low 1 2 2 2 1
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_576948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005498260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC086550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000081037   ⟹   ENSRNOP00000069644
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX21,499,934 - 21,598,876 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000090890   ⟹   ENSRNOP00000071818
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX21,499,934 - 21,539,503 (+)Ensembl
RefSeq Acc Id: XR_001835014
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
CeleraX21,155,560 - 21,282,178 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001835015
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
CeleraX21,155,560 - 21,282,178 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001835016
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
CeleraX21,155,565 - 21,282,178 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001835017
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
CeleraX21,155,564 - 21,282,178 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001835018
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
CeleraX21,155,560 - 21,282,178 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001835019
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
CeleraX21,153,324 - 21,282,178 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001835020
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
CeleraX21,152,936 - 21,282,178 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001835021
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
CeleraX21,155,560 - 21,282,178 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001835022
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
CeleraX21,155,560 - 21,282,178 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001835023
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
CeleraX21,155,560 - 21,282,567 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001835024
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
CeleraX21,155,560 - 21,282,178 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001835025
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
CeleraX21,180,638 - 21,282,178 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001835026
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
CeleraX21,155,560 - 21,282,178 (+)NCBI
Sequence:
RefSeq Acc Id: XR_001842623
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X21,474,627 - 21,603,348 (+)NCBI
Sequence:
RefSeq Acc Id: XR_005498222
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,001,378 (+)NCBI
RefSeq Acc Id: XR_005498223
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498224
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498225
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498226
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498227
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498228
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498229
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,871,792 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498230
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498231
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498232
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,871,278 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498233
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,871,278 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498234
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,871,576 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498236
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,871,330 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498237
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498238
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498239
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498240
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498242
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498243
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498244
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498245
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,001,378 (+)NCBI
RefSeq Acc Id: XR_005498246
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498247
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498248
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498249
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498250
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498251
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498253
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498254
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498255
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,000,989 (+)NCBI
RefSeq Acc Id: XR_005498256
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,001,378 (+)NCBI
RefSeq Acc Id: XR_005498257
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,001,378 (+)NCBI
RefSeq Acc Id: XR_005498259
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,001,378 (+)NCBI
RefSeq Acc Id: XR_005498260
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X20,873,839 - 21,001,378 (+)NCBI
RefSeq Acc Id: XR_589680
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
CeleraX21,155,560 - 21,282,178 (+)NCBI
Sequence:
RefSeq Acc Id: XR_589682
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
CeleraX21,155,560 - 21,282,178 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_576948 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH86550 (Get FASTA)   NCBI Sequence Viewer  
  P51593 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: ENSRNOP00000071818   ⟸   ENSRNOT00000090890
RefSeq Acc Id: ENSRNOP00000069644   ⟸   ENSRNOT00000081037
Protein Domains
DUF908   DUF913   HECT   UBA   WWE

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561763 AgrOrtholog
Ensembl Genes ENSRNOG00000061262 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000069644 UniProtKB/TrEMBL
  ENSRNOP00000071818 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000081037 UniProtKB/TrEMBL
  ENSRNOT00000090890 UniProtKB/TrEMBL
Gene3D-CATH 3.30.720.50 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7302447 IMAGE-MGC_LOAD
InterPro ARM-type_fold UniProtKB/TrEMBL
  DUF4414 UniProtKB/TrEMBL
  E3_Ub_ligase_DUF908 UniProtKB/TrEMBL
  E3_Ub_ligase_DUF913 UniProtKB/TrEMBL
  HECT_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hect_E3_ubiquitin_ligase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBA UniProtKB/TrEMBL
  UBA-like UniProtKB/TrEMBL
  UBA_HUWE1 UniProtKB/TrEMBL
  WWE-dom UniProtKB/TrEMBL
  WWE_dom_sf UniProtKB/TrEMBL
MGC_CLONE MGC:105964 IMAGE-MGC_LOAD
NCBI Gene Huwe1 ENTREZGENE
Pfam DUF4414 UniProtKB/TrEMBL
  DUF908 UniProtKB/TrEMBL
  DUF913 UniProtKB/TrEMBL
  HECT UniProtKB/Swiss-Prot
  UBA UniProtKB/TrEMBL
  WWE UniProtKB/TrEMBL
PhenoGen Huwe1 PhenoGen
PROSITE HECT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBA UniProtKB/TrEMBL
  WWE UniProtKB/TrEMBL
SMART HECTc UniProtKB/Swiss-Prot
  UBA UniProtKB/TrEMBL
Superfamily-SCOP SSF117839 UniProtKB/TrEMBL
  SSF46934 UniProtKB/TrEMBL
  SSF48371 UniProtKB/TrEMBL
  SSF56204 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JVW5_RAT UniProtKB/TrEMBL
  E9PSZ5_RAT UniProtKB/TrEMBL
  HUWE1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-10 Huwe1  HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1  Huwe1  HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-08-09 Huwe1  HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase  LOC501546  hypothetical protein LOC501546  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 LOC501546  hypothetical protein LOC501546      Symbol and Name status set to provisional 70820 PROVISIONAL