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Gene: Kdm5c (lysine demethylase 5C) Rattus norvegicus
Symbol: Kdm5c
Name: lysine demethylase 5C
RGD ID: 1560601
Description: Predicted to have histone demethylase activity (H3-K4 specific) and zinc ion binding activity. Involved in response to toxic substance. Predicted to localize to cytosol and nucleoplasm. Biomarker of schizophrenia. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Claes-Jensen type. Orthologous to human KDM5C (lysine demethylase 5C); PARTICIPATES IN histone modification pathway; renal cell carcinoma pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC102555632; LOC317432; lysine (K)-specific demethylase 5C; lysine-specific demethylase 5C; RGD1560601; similar to Jumonji/ARID domain-containing protein 1C (SmcX protein); similar to Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein); uncharacterized LOC102555632
Homo sapiens (human) : KDM5C (lysine demethylase 5C)  HGNC  Alliance
Mus musculus (house mouse) : Kdm5c (lysine (K)-specific demethylase 5C)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdm5c (lysine demethylase 5C)
Pan paniscus (bonobo/pygmy chimpanzee) : KDM5C (lysine demethylase 5C)
Canis lupus familiaris (dog) : KDM5C (lysine demethylase 5C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdm5c (lysine demethylase 5C)
Sus scrofa (pig) : KDM5C (lysine demethylase 5C)
Chlorocebus sabaeus (African green monkey) : KDM5C (lysine demethylase 5C)
Heterocephalus glaber (naked mole-rat) : Kdm5c (lysine demethylase 5C)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0X22,302,664 - 22,349,298 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX22,302,485 - 22,348,627 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X64,226,119 - 64,277,476 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X41,742,803 - 41,779,479 (+)NCBIRGSC3.4rn4RGSC3.4
CeleraX21,607,558 - 21,644,634 (+)NCBICelera
Cytogenetic MapXq13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Kdm5c
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1560601
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.