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Gene: Kdm5c (lysine demethylase 5C) Rattus norvegicus
Symbol: Kdm5c
Name: lysine demethylase 5C
Description: Predicted to have histone demethylase activity (H3-K4 specific) and zinc ion binding activity. Involved in response to toxic substance. Predicted to localize to the cytosol and nucleoplasm. Biomarker of schizophrenia. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Claes-Jensen type. Orthologous to human KDM5C (lysine demethylase 5C); PARTICIPATES IN histone modification pathway; renal cell carcinoma pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC102555632; LOC317432; lysine (K)-specific demethylase 5C; lysine-specific demethylase 5C; RGD1560601; similar to Jumonji/ARID domain-containing protein 1C (SmcX protein); similar to Jumonji/ARID domain-containing protein 1C (SmcX protein) (Xe169 protein); uncharacterized LOC102555632
Homo sapiens (human) : KDM5C (lysine demethylase 5C)  HGNC  Alliance
Mus musculus (house mouse) : Kdm5c (lysine (K)-specific demethylase 5C)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdm5c (lysine demethylase 5C)
Pan paniscus (bonobo/pygmy chimpanzee) : KDM5C (lysine demethylase 5C)
Canis lupus familiaris (dog) : KDM5C (lysine demethylase 5C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdm5c (lysine demethylase 5C)
Sus scrofa (pig) : KDM5C (lysine demethylase 5C)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0X22,302,664 - 22,349,298 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X64,226,119 - 64,277,476 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X41,742,803 - 41,779,479 (+)NCBIRGSC3.4rn4RGSC3.4
CeleraX21,607,558 - 21,644,634 (+)NCBICelera
Cytogenetic MapXq13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Kdm5c
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1560601
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.