Ap1s2 (adaptor related protein complex 1 subunit sigma 2)

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Gene: Ap1s2 (adaptor related protein complex 1 subunit sigma 2) Rattus norvegicus

Analyze

Symbol:

Ap1s2

Name:

adaptor related protein complex 1 subunit sigma 2

RGD ID:

1561862

Description:

Predicted to enable clathrin adaptor activity. Predicted to be involved in synaptic vesicle budding from endosome. Predicted to act upstream of or within several processes, including adipose tissue development; fat cell differentiation; and visual learning. Predicted to be located in Golgi apparatus and synapse. Predicted to be part of AP-1 adaptor complex. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability 5. Orthologous to human AP1S2 (adaptor related protein complex 1 subunit sigma 2); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

adaptor-related protein complex 1, sigma 2 subunit; AP-1 complex subunit sigma-2; LOC302671; RGD1561862; similar to Adapter-related protein complex 1 sigma 1B subunit (Sigma-adaptin 1B) (Adaptor protein complex AP-1 sigma-1B subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Clathrin assembly protein complex 1 sigma-1B small chain) (Sigma 1B s...; similar to Adapter-related protein complex 1 sigma 2 subunit (Sigma-adaptin 1B)

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	X	30,572,746 - 30,598,961 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	30,572,751 - 30,597,262 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	31,605,829 - 31,631,914 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	35,042,629 - 35,068,714 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	31,230,051 - 31,256,138 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	32,329,883 - 32,376,301 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	32,329,598 - 32,355,307 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	32,691,539 - 32,717,224 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	51,329,574 - 51,356,406 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	30,915,890 - 30,941,975 (-)	NCBI		Celera
Cytogenetic Map	X	q14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Experimental Liver Cirrhosis (ISO)

Fanconi anemia (ISO)

genetic disease (ISO)

multiple congenital anomalies-hypotonia-seizures syndrome 2 (ISO)

Neurodevelopmental Disorders (ISO)

syndromic X-linked intellectual disability 5 (ISO,ISS)

syndromic X-linked intellectual disability Lubs type (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(-)-demecolcine (ISO)

(1->4)-beta-D-glucan (ISO)

1,1-dichloroethene (ISO)

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (EXP,ISO)

17beta-estradiol 3-benzoate (EXP)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2-methylcholine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-diaminodiphenylmethane (EXP,ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amitrole (EXP)

antirheumatic drug (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

butanal (ISO)

carmustine (ISO)

CGP 52608 (ISO)

choline (ISO)

cisplatin (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

cylindrospermopsin (ISO)

dexamethasone (ISO)

dibutyl phthalate (ISO)

diuron (EXP)

dorsomorphin (ISO)

endosulfan (EXP)

ethanol (ISO)

folic acid (ISO)

formaldehyde (ISO)

furan (EXP)

genistein (ISO)

indometacin (ISO)

isobutanol (ISO)

L-methionine (ISO)

methapyrilene (EXP)

methimazole (EXP)

methyl methanesulfonate (ISO)

methylparaben (ISO)

N-nitrosodimethylamine (EXP)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

phenylmercury acetate (ISO)

pioglitazone (ISO)

pirinixic acid (ISO)

quercetin (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium fluoride (EXP)

tamibarotene (ISO)

temozolomide (ISO)

testosterone (EXP)

tetrachloromethane (EXP,ISO)

thioacetamide (EXP)

trichostatin A (ISO)

tris(2-butoxyethyl) phosphate (ISO)

valproic acid (ISO)

vincristine (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adipose tissue development (ISO)

biological_process (ND)

establishment of localization in cell (ISO)

fat cell differentiation (ISO)

intracellular protein transport (IEA)

neuromuscular process controlling balance (ISO)

synaptic vesicle budding from endosome (ISO)

synaptic vesicle recycling (ISO)

vesicle-mediated transport (IBA,ISO)

visual learning (ISO)

Cellular Component

AP-1 adaptor complex (IEA)

clathrin-coated pit (IEA)

Golgi apparatus (ISO)

intracellular membrane-bounded organelle (IBA,ISO)

presynapse (IEA)

synapse (ISO)

Molecular Function

clathrin adaptor activity (IEA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
3.	Gamma-synergin: an EH domain-containing protein that interacts with gamma-adaptin.	Page LJ, etal., J Cell Biol 1999 Sep 6;146(5):993-1004.
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:12477932	PMID:20203623	PMID:24928897

Genomics

Comparative Map Data

Ap1s2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	X	30,572,746 - 30,598,961 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	30,572,751 - 30,597,262 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	31,605,829 - 31,631,914 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	35,042,629 - 35,068,714 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	31,230,051 - 31,256,138 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	32,329,883 - 32,376,301 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	32,329,598 - 32,355,307 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	32,691,539 - 32,717,224 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	51,329,574 - 51,356,406 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	30,915,890 - 30,941,975 (-)	NCBI		Celera
Cytogenetic Map	X	q14	NCBI

AP1S2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	15,825,806 - 15,854,813 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	15,825,806 - 15,854,931 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	15,843,929 - 15,872,936 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	15,753,850 - 15,783,021 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	15,603,585 - 15,632,757	NCBI
Celera	X	19,961,411 - 19,990,500 (-)	NCBI		Celera
Cytogenetic Map	X	p22.2	NCBI
HuRef	X	13,597,581 - 13,626,785 (-)	NCBI		HuRef
CHM1_1	X	15,874,896 - 15,904,078 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	X	15,408,728 - 15,437,727 (-)	NCBI		T2T-CHM13v2.0

Ap1s2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	162,691,427 - 162,716,662 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	162,692,013 - 162,716,662 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	163,908,454 - 163,933,666 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	163,909,017 - 163,933,666 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	160,347,092 - 160,367,478 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	159,253,265 - 159,273,651 (+)	NCBI		MGSCv36	mm8
Celera	X	147,128,574 - 147,148,961 (+)	NCBI		Celera
Cytogenetic Map	X	F5	NCBI
cM Map	X	75.97	NCBI

Ap1s2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955519	2,351,754 - 2,370,650 (+)	NCBI	ChiLan1.0	ChiLan1.0

AP1S2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	X	17,625,917 - 17,655,154 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	8,449,885 - 8,478,932 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	15,807,475 - 15,835,938 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	15,807,476 - 15,836,172 (-)	Ensembl	panpan1.1		panPan2

AP1S2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	12,075,797 - 12,105,911 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	12,076,724 - 12,103,654 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	11,926,084 - 11,956,371 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	12,037,006 - 12,067,314 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	12,037,006 - 12,067,320 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	12,106,135 - 12,136,551 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	12,093,621 - 12,123,810 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	12,118,821 - 12,149,359 (-)	NCBI		UU_Cfam_GSD_1.0

Ap1s2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	5,251,240 - 5,289,320 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936470	5,257,542 - 5,289,469 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936470	5,260,984 - 5,301,552 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

AP1S2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	12,367,795 - 12,397,677 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	12,367,785 - 12,397,672 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	13,312,013 - 13,341,898 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

AP1S2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	14,283,175 - 14,310,453 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666056	16,136,637 - 16,164,845 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ap1s2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624829	608,065 - 634,479 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624829	608,065 - 637,096 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ap1s2
45 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	431
Count of miRNA genes:	216
Interacting mature miRNAs:	268
Transcripts:	ENSRNOT00000065075
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
731181	Uae27	Urinary albumin excretion QTL 27	2.7	0.0059	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	X	1	43491017	Rat
70165	Bp64	Blood pressure QTL 64	5.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	X	1448129	31706553	Rat
1298071	Edpm12	Estrogen-dependent pituitary mass QTL 12	3.2		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	X	2927898	47927898	Rat
10755455	Coatc13	Coat color QTL 13		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	4406000	49406000	Rat
631666	Iddm5	Insulin dependent diabetes mellitus QTL 5			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	X	4494549	49494549	Rat
61430	Cia18	Collagen induced arthritis QTL 18	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	14843113	120568734	Rat
71116	Niddm16	Non-insulin dependent diabetes mellitus QTL 16	7.81		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	X	15297802	60297802	Rat
1598873	Memor2	Memory QTL 2	2.5		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	X	20990947	41052531	Rat
2290375	Gluco34	Glucose level QTL 34	2.75		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	X	20990947	41203591	Rat

Markers in Region

RH130941

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	30,572,792 - 30,572,981 (+)	MAPPER	mRatBN7.2
Rnor_6.0	X	32,329,927 - 32,330,115	NCBI	Rnor6.0
Rnor_5.0	X	32,691,585 - 32,691,773	UniSTS	Rnor5.0
RGSC_v3.4	X	51,329,618 - 51,329,806	UniSTS	RGSC3.4
Celera	X	30,915,934 - 30,916,122	UniSTS
RH 3.4 Map	X	427.23	UniSTS
Cytogenetic Map	X	q21	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	2	39	8		19		6	8	74	2	33	11	6
Low	1	4	49	41		41	2	3		33	8		2
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001127531	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006256860	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006256862	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017602005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017602006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017602007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017602009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017602010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039099658	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039099659	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039099660	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039099661	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005497961	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC166480	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213449	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ235170	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000384	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000065075 ⟹ ENSRNOP00000063764

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	30,572,751 - 30,597,262 (-)	Ensembl
Rnor_6.0 Ensembl	X	32,329,883 - 32,355,307 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000081652 ⟹ ENSRNOP00000070442

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	30,573,222 - 30,597,262 (-)	Ensembl
Rnor_6.0 Ensembl	X	32,329,598 - 32,355,296 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000097825 ⟹ ENSRNOP00000086354

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	30,576,666 - 30,597,262 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000113986 ⟹ ENSRNOP00000082726

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	30,573,222 - 30,597,262 (-)	Ensembl

RefSeq Acc Id:

NM_001127531 ⟹ NP_001121003

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	X	30,572,749 - 30,598,832 (-)	NCBI
Rnor_6.0	X	32,329,883 - 32,355,307 (-)	NCBI
Rnor_5.0	X	32,691,539 - 32,717,224 (-)	NCBI
RGSC_v3.4	X	51,329,574 - 51,356,406 (-)	RGD
Celera	X	30,915,890 - 30,941,975 (-)	RGD

Sequence:

show sequence

CTCCCCGCGGCACCACGGCTTCCCTTCAACAGCCTGGCGACGGGGGCTTCCCCTCAGCAGCTGC
CGGCGCCTCAGTCTCCGCAGCCAGCCAAGCTCCGCCGCGTCCGCGGCCCGCAGCCGCCATGCAG
TTTATGTTGCTTTTTAGTCGTCAGGGAAAGCTTCGACTGCAGAAATGGTATGTCCCACTGTCAG
ACAAAGAGAAGAAGAAAATCACCAGAGAACTTGTGCAAACCGTTTTAGCACGGAAACCCAAGAT
GTGCAGCTTCCTTGAGTGGAGAGATCTGAAGATTGTTTATAAAAGATATGCCAGTCTATATTTT
TGCTGTGCTATTGAGGATCAGGACAATGAACTGATTACCCTGGAAATAATCCATCGTTATGTGG
AATTACTTGACAAGTATTTTGGCAGTGTGTGTGAACTTGATATCATCTTTAATTTTGAGAAGGC
CTATTTTATTTTGGATGAATTTCTTTTGGGAGGAGAAGTTCAGGAAACATCAAAGAAAAATGTC
CTTAAAGCAATTGAGCAGGCTGATCTCCTGCAGGAGGAAGCTGAAACCCCACGTAGTGTTCTTG
AAGAAATTGGACTGACATAACTGTCCTCCCTTGCTGATGACTTCTTGTGGCATTTCACACTGTA
GATGGTCACTGCCTCCCATGTCCATGTTAGCTAACGGTGTAAGATGATGTCTTGTCAGTATTAC
TGTTTTGCTAAGCTGCTTCATTCAGGCCTACCCAATTTTTTTTAAAGGGAACTTTGGTTAATCA
AATGATAAATGAAGGGACATAAATATGAATTAGGAAGATGTAGAAAAAGTAACATACCACTTCT
GGACATCTTAAAGTTTAAAGGTCAGTCTCATAATTATGTGCTTATATAAAAATATGTCTATTAC
ATGTATATCCAACAATTTGGCAAAATATATTTACAATTGTACTTCAACAAGGAAACTTAAATTA
TGTGAAACCTGGTTTAATGAAACCAAAGACTAGAGTAGCATTTCAGTATATATAAGAATGAAGG
GAATTGACATATGAATGAAAGTTTATTGAAAATTTAAGCAACCAAATTTCTACCAAAGACCCAT
ATTAGATACAACATACATTAAAACAAAAGGAATATAGATGCTTTTAGAGGACTATCTTAGAATG
ATGCTGTTTTATACTAAAATTCATTAAGTATTCTGAATGAATGGGACAAGGAACAAAGACTTTC
CTAATCTTGAGCACATAATTTTTAAGGCCAAGTAACATTTGATTCCCTGAGGTGAAGTTTTCGT
GGTCATAATCATGTAGTTGTTTTTGATGCCCCAAATAAAATAGGATGGTTAATTACCAGGTATT
CTTCATAATAGTATGTTGCTTTCCTCACAGAGTATTACATAAAGTCATTATCTAAAGCATGATG
TTCCTTCTAGGGTGCTTGTTAAAGCCAAATTTATTTTGCTTCCCTATTGCTTCCTTCCAGTTAG
AAGTGCTGCAGACTTGACAGCAGCTCCCTATCCTTTCATGTCACTGCCTAGTCGTCGGAAGTCT
TATGACAGCTTAAAAGATACCTTTCGTATAGCAAAGTGAGAGTTGACTGAAGCAAAGTGGCATT
GGTTGGCCCTATATTTTTTGAAGCTGTATAAATTCCTGGCATCACTTTTATACATCCTGACACA
TACCTGAACACATCTCCCTGATTTCTATGTTCCCTTGTAATATGCTAGGCTGGAGTAAGCTTTG
CTGTGATTGTGAACAACTTTCAAGCCACCTGAACACTGTCTTATCACATCACCAATTAATGGTA
ATAAATGTTCTGCAAACACAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006256860 ⟹ XP_006256922

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	X	30,572,746 - 30,598,953 (-)	NCBI
Rnor_6.0	X	32,329,883 - 32,355,440 (-)	NCBI
Rnor_5.0	X	32,691,539 - 32,717,224 (-)	NCBI

Sequence:

show sequence

CTTGGCGCGCGTCCTCTGGTCCGCCTCTCAGCTCACCGCAGCCTGGGCTCCTCCTTCGTCCAGC
CTCCAGGGCGGGATCTGTTGGCTCGCCCTACCCTCGCCGCCTAAGCCTGCCCTCCACCAGACGG
GTCCCCTCCCCGCGGCACCACGGCTTCCCTTCAACAGCCTGGCGACGGGGGCTTCCCCTCAGCA
GCTGCCGGCGCCTCAGTCTCCGCAGCCAGCCAAGCTCCGCCGCGTCCGCGGCCCGCAGCCGCCA
TGCAGTTTATGTTGCTTTTTAGTCGTCAGGGAAAGCTTCGACTGCAGAAATGGTATGTCCCACT
GTCAGACAAAGAGAAGAAGAAAATCACCAGAGAACTTGTGCAAACCGTTTTAGCACGGAAACCC
AAGATGTGCAGCTTCCTTGAGTGGAGAGATCTGAAGATTGTTTATAAAAGATATGCCAGTCTAT
ATTTTTGCTGTGCTATTGAGGATCAGGACAATGAACTGATTACCCTGGAAATAATCCATCGTTA
TGTGGAATTACTTGACAAGTATTTTGGCAGTGTGTGTGAACTTGATATCATCTTTAATTTTGAG
AAGGCCTATTTTATTTTGGATGAATTTCTTTTGGGAGGAGAAGTTCAGGAAACATCAAAGAAAA
ATGTCCTTAAAGCAATTGAGCAGGCTGATCTCCTGCAGGAGGATGCAAAAGAAGCTGAAACCCC
ACGTAGTGTTCTTGAAGAAATTGGACTGACATAACTGTCCTCCCTTGCTGATGACTTCTTGTGG
CATTTCACACTGTAGATGGTCACTGCCTCCCATGTCCATGTTAGCTAACGGTGTAAGATGATGT
CTTGTCAGTATTACTGTTTTGCTAAGCTGCTTCATTCAGGCCTACCCAATTTTTTTTAAAGGGA
ACTTTGGTTAATCAAATGATAAATGAAGGGACATAAATATGAATTAGGAAGATGTAGAAAAAGT
AACATACCACTTCTGGACATCTTAAAGTTTAAAGGTCAGTCTCATAATTATGTGCTTATATAAA
AATATGTCTATTACATGTATATCCAACAATTTGGCAAAATATATTTACAATTGTACTTCAACAA
GGAAACTTAAATTATGTGAAACCTGGTTTAATGAAACCAAAGACTAGAGTAGCATTTCAGTATA
TATAAGAATGAAGGGAATTGACATATGAATGAAAGTTTATTGAAAATTTAAGCAACCAAATTTC
TACCAAAGACCCATATTAGATACAACATACATTAAAACAAAAGGAATATAGATGCTTTTAGAGG
ACTATCTTAGAATGATGCTGTTTTATACTAAAATTCATTAAGTATTCTGAATGAATGGGACAAG
GAACAAAGACTTTCCTAATCTTGAGCACATAATTTTTAAGGCCAAGTAACATTTGATTCCCTGA
GGTGAAGTTTTCGTGGTCATAATCATGTAGTTGTTTTTGATGCCCCAAATAAAATAGGATGGTT
AATTACCAGGTATTCTTCATAATAGTATGTTGCTTTCCTCACAGAGTATTACATAAAGTCATTA
TCTAAAGCATGATGTTCCTTCTAGGGTGCTTGTTAAAGCCAAATTTATTTTGCTTCCCTATTGC
TTCCTTCCAGTTAGAAGTGCTGCAGACTTGACAGCAGCTCCCTATCCTTTCATGTCACTGCCTA
GTCGTCGGAAGTCTTATGACAGCTTAAAAGATACCTTTCGTATAGCAAAGTGAGAGTTGACTGA
AGCAAAGTGGCATTGGTTGGCCCTATATTTTTTGAAGCTGTATAAATTCCTGGCATCACTTTTA
TACATCCTGACACATACCTGAACACATCTCCCTGATTTCTATGTTCCCTTGTAATATGCTAGGC
TGGAGTAAGCTTTGCTGTGATTGTGAACAACTTTCAAGCCACCTGAACACTGTCTTATCACATC
ACCAATTAATGGTAATAAATGTTCTGCAAACAC

hide sequence

RefSeq Acc Id:

XM_006256862 ⟹ XP_006256924

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	X	30,576,660 - 30,598,958 (-)	NCBI
Rnor_6.0	X	32,333,795 - 32,355,441 (-)	NCBI
Rnor_5.0	X	32,691,539 - 32,717,224 (-)	NCBI

Sequence:

show sequence

GCTTGGCGCGCGTCCTCTGGTCCGCCTCTCAGCTCACCGCAGCCTGGGCTCCTCCTTCGTCCAG
CCTCCAGGGCGGGATCTGTTGGCTCGCCCTACCCTCGCCGCCTAAGCCTGCCCTCCACCAGACG
GGTCCCCTCCCCGCGGCACCACGGCTTCCCTTCAACAGCCTGGCGACGGGGGCTTCCCCTCAGC
AGCTGCCGGCGCCTCAGTCTCCGCAGCCAGCCAAGCTCCGCCGCGTCCGCGGCCCGCAGCCGCC
ATGCAGTTTATGTTGCTTTTTAGTCGTCAGGGAAAGCTTCGACTGCAGAAATGGTATGTCCCAC
TGTCAGACAAAGAGAAGAAGAAAATCACCAGAGAACTTGTGCAAACCGTTTTAGCACGGAAACC
CAAGATGTGCAGCTTCCTTGAGTGGAGAGATCTGAAGATTGTTTATAAAAGATATGCCAGTCTA
TATTTTTGCTGTGCTATTGAGGATCAGGACAATGAACTGATTACCCTGGAAATAATCCATCGTT
ATGTGGAATTACTTGACAAGTATTTTGGCAGTGTGTGTGAACTTGATATCATCTTTAATTTTGA
GAAGGCCTATTTTATTTTGGATGAATTTCTTTTGGGAGGAGAAGTTCAGGAAACATCAAAGAAA
AATGTCCTTAAAGCAATTGAGCAGGCTGATCTCCTGCAGGAGCCACGCCATGAATATTTTAATG
TCCCTGTGTACTAATGACTGCTCATCGACTATGCAGAATTTCACAGAGGAAATAGAGAACTGAT
ATACTTATGAAAGAAAATGTCCTCAGCTTGGTGACTAATTCTCCTGTAAAATAATATATAGCAT
CTTAGAACTAGTACCTTTATGATTGTATTTTTTTCTGTGCCTATTCTTAATTCTATTTATTTTG
TATATGATATTGACATAGTTTTTTCTGTCTACTACTGATTTCTTCTTGACAAAATATGACTTGT
GAATGTTTTGATTAATATTCTGAACACATACAAGTTATCATTAGTAAATAATCTGTGATTAATC
TTATGAGAGTATAAGTGAAAGACCGGGGACAATCACAAATGTTTACCAAAGAAAACAGTTAGGA
GCTCAGGCAAAATTAGGCATACCACAATATTTAATGTAGTTTGATCTTCCACTGTTGAAGAAAG
CCAAGCTTTATTTAGTGCTAAGATTATCTTACAGTCTGTATGAGCTAATATGTTGGACTGTATC
ACATAAAAGTGTATGTTGGAACAGTATAAGAAAAATCAATTGTATAATTCTCTAAGATCTAAGG
TTAAAACATTTCAATTTTTAAGAAATTTTGTATTGCCAATATTTATTAAGCCACATTTGTGCAG
TGTCAAAAGTCCCTTTATGAACTGTCAGAAAACTATGTCACAAAGTCTCCTGTATTGTTGCTCA
GTAACAGCCCTTGAGTCAGTAATACTGAGCCTACCCATGTGATACAAAAATTCAGATAATCATT
TTTAATATCCAAACATTTATAGTTTATTAATTAATGGCTTCCTAATTAATATATTAAGCCTTCT
TCTAAACATTCAGTGATGTGTTAACTATGCTTGTATATTTTGGAATACTAAAAACTTTTAATAT
TAATTTTATATAAATATGGTTTTAATAAGCAGCAAATTGAGACTTTAAAACCTAAGTAAATTTT
TACTAAACAATAACTTAGGAGGCATGGTAGTGCATGCCTGTCATCCTAGTACTTGGGAGGCTGA
GGCAAAAGGAAGATGAGGTACTATAGTACCTAGGGCATCCCTGTCTCAAAAGACAAAAAAGCTA
AGTATGCCAAAAAACTCTAGTAACTTCAGAAGGTACCCTTACCAGTTTCCCACTGAAAGAAGAT
CTAGGAAATGTTTTAGGAAATGCAGTGTTAGGCAGCTGTACAGCTCAGCGCTCTCCATTGCCAT
CTGCAACATCACAAAGCATTGGTCTTTCATTTCCATTTTTCCCATCCTCCCACACTACATGTTG
TTCATCTGATTTTAATGTTGCATAAATATGCATTGTCTCATGCCTGTTTGTTTTGGTTGCTGTG
TGCTGAGCTGTAAGAAAATGTTGTGCTTTTGTGGGGGGATTATCTGTATACAGCTGCTTGCTTT
AAATTAGCAGATTCTGAAATAGCTTTTTCTTGCATGTCTAAAATAAAGTATTGCATGTACTTTG

hide sequence

RefSeq Acc Id:

XM_039099658 ⟹ XP_038955586

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	X	30,576,660 - 30,598,961 (-)	NCBI

RefSeq Acc Id:

XM_039099659 ⟹ XP_038955587

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	X	30,576,660 - 30,598,961 (-)	NCBI

RefSeq Acc Id:

XM_039099660 ⟹ XP_038955588

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	X	30,576,660 - 30,598,961 (-)	NCBI

RefSeq Acc Id:

XM_039099661 ⟹ XP_038955589

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	X	30,572,746 - 30,594,447 (-)	NCBI

RefSeq Acc Id:

XR_005497961

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	X	30,572,746 - 30,598,960 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001121003	(Get FASTA)	NCBI Sequence Viewer
	XP_006256922	(Get FASTA)	NCBI Sequence Viewer
	XP_006256924	(Get FASTA)	NCBI Sequence Viewer
	XP_038955586	(Get FASTA)	NCBI Sequence Viewer
	XP_038955587	(Get FASTA)	NCBI Sequence Viewer
	XP_038955588	(Get FASTA)	NCBI Sequence Viewer
	XP_038955589	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI66480	(Get FASTA)	NCBI Sequence Viewer
	EDL90507	(Get FASTA)	NCBI Sequence Viewer
	EDL90508	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000063764
	ENSRNOP00000063764.1
	ENSRNOP00000070442.1
	ENSRNOP00000082726
	ENSRNOP00000082726.1
	ENSRNOP00000086354
	ENSRNOP00000086354.1

RefSeq Acc Id:	NP_001121003 ⟸ NM_001127531
- UniProtKB:	B2GV08 (UniProtKB/TrEMBL), A6K2M2 (UniProtKB/TrEMBL), F7F749 (UniProtKB/TrEMBL)
- Sequence:	show sequence MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASL YFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKK NVLKAIEQADLLQEEAETPRSVLEEIGLT hide sequence

RefSeq Acc Id:	XP_006256922 ⟸ XM_006256860
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5ZVG9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASL YFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKK NVLKAIEQADLLQEDAKEAETPRSVLEEIGLT hide sequence

RefSeq Acc Id:	XP_006256924 ⟸ XM_006256862
- Peptide Label:	isoform X3
- Sequence:	show sequence MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASL YFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKK NVLKAIEQADLLQEPRHEYFNVPVY hide sequence

RefSeq Acc Id:

ENSRNOP00000063764 ⟸ ENSRNOT00000065075

RefSeq Acc Id:

ENSRNOP00000070442 ⟸ ENSRNOT00000081652

RefSeq Acc Id:	XP_038955589 ⟸ XM_039099661
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038955587 ⟸ XM_039099659
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6A5U3 (UniProtKB/TrEMBL), A6K2M3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038955588 ⟸ XM_039099660
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6A5U3 (UniProtKB/TrEMBL), A6K2M3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038955586 ⟸ XM_039099658
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6A5U3 (UniProtKB/TrEMBL), A6K2M3 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000086354 ⟸ ENSRNOT00000097825

RefSeq Acc Id:

ENSRNOP00000082726 ⟸ ENSRNOT00000113986

Protein Domains

AP complex mu/sigma subunit

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B2GV08-F1-model_v2	AlphaFold	B2GV08	1-157	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701801

Promoter ID:

EPDNEW_R12325

Type:

multiple initiation site

Name:

Ap1s2_1

Description:

adaptor-related protein complex 1, sigma 2 subunit

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	X	32,355,318 - 32,355,378	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1561862	AgrOrtholog
BioCyc Gene	G2FUF-2569	BioCyc
Ensembl Genes	ENSRNOG00000038686	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000065075	ENTREZGENE
	ENSRNOT00000065075.4	UniProtKB/TrEMBL
	ENSRNOT00000081652.2	UniProtKB/TrEMBL
	ENSRNOT00000097825	ENTREZGENE
	ENSRNOT00000097825.1	UniProtKB/TrEMBL
	ENSRNOT00000113986	ENTREZGENE
	ENSRNOT00000113986.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.450.60	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:9102341	IMAGE-MGC_LOAD
InterPro	AP1_sigma	UniProtKB/TrEMBL
	AP_complex_ssu	UniProtKB/TrEMBL
	AP_mu_sigma_su	UniProtKB/TrEMBL
	Clathrin_sigma/coatomer_zeta	UniProtKB/TrEMBL
	Longin-like	UniProtKB/TrEMBL
KEGG Report	rno:302671	UniProtKB/TrEMBL
MGC_CLONE	MGC:187937	IMAGE-MGC_LOAD
NCBI Gene	302671	ENTREZGENE
PANTHER	AP-1 COMPLEX SUBUNIT SIGMA-2	UniProtKB/TrEMBL
	PTHR11753	UniProtKB/TrEMBL
Pfam	Clat_adaptor_s	UniProtKB/TrEMBL
PharmGKB	AP1S2	RGD
PhenoGen	Ap1s2	PhenoGen
PIRSF	AP_complex_sigma	UniProtKB/TrEMBL
PROSITE	CLAT_ADAPTOR_S	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000038686	RatGTEx
Superfamily-SCOP	Longin_like	UniProtKB/TrEMBL
UniProt	A0A0G2JXX9_RAT	UniProtKB/TrEMBL
	A0A8I5ZVG9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A5U3	ENTREZGENE, UniProtKB/TrEMBL
	A6K2M2	ENTREZGENE, UniProtKB/TrEMBL
	A6K2M3	ENTREZGENE, UniProtKB/TrEMBL
	B2GV08	ENTREZGENE
	F7F749	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	B2GV08	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-05-03	Ap1s2	adaptor related protein complex 1 subunit sigma 2	Ap1s2	adaptor-related protein complex 1, sigma 2 subunit	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Ap1s2	adaptor-related protein complex 1, sigma 2 subunit	Ap1s2_predicted	adaptor-related protein complex 1, sigma 2 subunit (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-30	Ap1s2_predicted	adaptor-related protein complex 1, sigma 2 subunit (predicted)	RGD1561862_predicted	similar to Adapter-related protein complex 1 sigma 2 subunit (Sigma-adaptin 1B) (predicted)	Symbol and Name updated	1299863	APPROVED
2006-03-10	RGD1561862_predicted	similar to Adapter-related protein complex 1 sigma 2 subunit (Sigma-adaptin 1B) (predicted)		similar to Adapter-related protein complex 1 sigma 1B subunit (Sigma-adaptin 1B) (Adaptor protein complex AP-1 sigma-1B subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Clathrin assembly protein complex 1 sigma-1B small chain) (Sigma 1B s... (predicted)	Name updated	1299863	APPROVED
2006-03-07	RGD1561862_predicted	similar to Adapter-related protein complex 1 sigma 1B subunit (Sigma-adaptin 1B) (Adaptor protein complex AP-1 sigma-1B subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Clathrin assembly protein complex 1 sigma-1B small chain) (Sigma 1B s... (predicted)	LOC302671	similar to Adapter-related protein complex 1 sigma 1B subunit (Sigma-adaptin 1B) (Adaptor protein complex AP-1 sigma-1B subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Clathrin assembly protein complex 1 sigma-1B small chain) (Sigma 1B s...	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC302671	similar to Adapter-related protein complex 1 sigma 1B subunit (Sigma-adaptin 1B) (Adaptor protein complex AP-1 sigma-1B subunit) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Clathrin assembly protein complex 1 sigma-1B small chain) (Sigma 1B s...			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - MGI

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