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Gene: Prps2 (phosphoribosyl pyrophosphate synthetase 2) Rattus norvegicus
Symbol: Prps2
Name: phosphoribosyl pyrophosphate synthetase 2
Description: Exhibits several functions, including magnesium ion binding activity; purine ribonucleotide binding activity; and ribose phosphate diphosphokinase activity. Involved in 5-phosphoribose 1-diphosphate biosynthetic process; AMP biosynthetic process; and animal organ regeneration. Localizes to the ribose phosphate diphosphokinase complex. Orthologous to human PRPS2 (phosphoribosyl pyrophosphate synthetase 2); PARTICIPATES IN de novo purine biosynthetic pathway; pentose phosphate pathway; purine metabolic pathway; INTERACTS WITH 17alpha-ethynylestradiol; ammonium chloride; amphetamine.
Type: protein-coding
Also known as: Phophoribosylpyrophosphate synthetase subunit II; Phophoribosylpyrophosphate synthetase, subunit II; phosphoribosyl pyrophosphate synthase II; phosphoribosyl pyrophosphate synthetase II; PRS-II; ribose-phosphate pyrophosphokinase 2
Homo sapiens (human) : PRPS2 (phosphoribosyl pyrophosphate synthetase 2)  HGNC  Alliance
Mus musculus (house mouse) : Prps2 (phosphoribosyl pyrophosphate synthetase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prps2 (phosphoribosyl pyrophosphate synthetase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PRPS2 (phosphoribosyl pyrophosphate synthetase 2)
Canis lupus familiaris (dog) : PRPS2 (phosphoribosyl pyrophosphate synthetase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prps2 (phosphoribosyl pyrophosphate synthetase 2)
Sus scrofa (pig) : PRPS2 (phosphoribosyl pyrophosphate synthetase 2)
Chlorocebus sabaeus (African green monkey) : PRPS2 (phosphoribosyl pyrophosphate synthetase 2)
Heterocephalus glaber (naked mole-rat) : Prps2 (phosphoribosyl pyrophosphate synthetase 2)
more info ...
Is Marker For: QTLs:   Iddm5  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0X28,435,275 - 28,472,882 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX28,435,507 - 28,472,880 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X28,831,387 - 28,868,992 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X47,274,362 - 47,315,274 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X47,327,830 - 47,368,743 (+)NCBI
CeleraX27,388,118 - 27,424,061 (+)NCBICelera
Cytogenetic MapXq13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Prps2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3415
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.