Ppp1r3f (protein phosphatase 1, regulatory subunit 3F) - Rat Genome Database

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Gene: Ppp1r3f (protein phosphatase 1, regulatory subunit 3F) Rattus norvegicus
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Symbol: Ppp1r3f
Name: protein phosphatase 1, regulatory subunit 3F
RGD ID: 1566398
Description: Predicted to enable glycogen binding activity and protein phosphatase binding activity. Predicted to act upstream of or within regulation of glycogen biosynthetic process. Predicted to be located in membrane; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine (ortholog); 3-isobutyl-1-methyl-7H-xanthine (ortholog); 4,4'-diaminodiphenylmethane (ortholog).
Type: protein-coding
RefSeq Status: INFERRED
Previously known as: LOC363453; protein phosphatase 1, regulatory (inhibitor) subunit 3F; RGD1566398; similar to DXImx48e protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X17,581,467 - 17,617,087 (+)NCBIGRCr8
mRatBN7.2X14,915,740 - 14,945,249 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX14,929,323 - 14,945,193 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0X15,774,091 - 15,784,711 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X16,571,568 - 16,574,909 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X26,960,930 - 26,982,406 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX15,013,524 - 15,028,435 (+)NCBICelera
Cytogenetic MapXq12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Ppp1r3f
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X17,581,467 - 17,617,087 (+)NCBIGRCr8
mRatBN7.2X14,915,740 - 14,945,249 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX14,929,323 - 14,945,193 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0X15,774,091 - 15,784,711 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X16,571,568 - 16,574,909 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X26,960,930 - 26,982,406 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX15,013,524 - 15,028,435 (+)NCBICelera
Cytogenetic MapXq12NCBI
PPP1R3F
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X49,269,793 - 49,301,469 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX49,269,793 - 49,301,461 (+)EnsemblGRCh38hg38GRCh38
GRCh37X49,126,256 - 49,144,552 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X49,013,261 - 49,031,021 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X48,882,687 - 48,900,448NCBI
CeleraX52,519,831 - 52,538,087 (-)NCBICelera
Cytogenetic MapXp11.23NCBI
HuRefX46,782,559 - 46,800,422 (+)NCBIHuRef
CHM1_1X49,158,606 - 49,176,873 (+)NCBICHM1_1
T2T-CHM13v2.0X48,681,633 - 48,713,324 (+)NCBIT2T-CHM13v2.0
Ppp1r3f
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X7,424,815 - 7,440,541 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX7,423,535 - 7,440,522 (-)EnsemblGRCm39 Ensembl
GRCm38X7,558,562 - 7,574,281 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX7,557,296 - 7,574,283 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X7,135,688 - 7,151,246 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X6,715,911 - 6,731,079 (-)NCBIMGSCv36mm8
CeleraX3,897,649 - 3,913,217 (+)NCBICelera
Cytogenetic MapXA1.1NCBI
cM MapX3.4NCBI
Ppp1r3f
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955543750,323 - 766,797 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955543750,094 - 767,894 (+)NCBIChiLan1.0ChiLan1.0
PPP1R3F
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X50,761,710 - 50,779,415 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X50,765,089 - 50,782,793 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X41,569,825 - 41,587,523 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X49,423,409 - 49,441,030 (+)NCBIpanpan1.1PanPan1.1panPan2
PPP1R3F
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X42,362,335 - 42,378,480 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX42,362,370 - 42,378,012 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX16,741,035 - 16,757,531 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X42,504,009 - 42,520,511 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX42,504,000 - 42,520,117 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X42,487,950 - 42,504,446 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X42,475,407 - 42,491,905 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X42,570,374 - 42,586,874 (+)NCBIUU_Cfam_GSD_1.0
Ppp1r3f
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X34,897,570 - 34,912,854 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367211,137,916 - 1,156,151 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367211,137,998 - 1,153,243 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP1R3F
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX43,328,274 - 43,344,013 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X43,328,199 - 43,344,503 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X48,176,169 - 48,192,444 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PPP1R3F
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X46,369,087 - 46,387,335 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX46,369,190 - 46,387,401 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607611,930,508 - 11,948,717 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppp1r3f
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248931,013,509 - 1,030,441 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248931,012,976 - 1,030,380 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ppp1r3f
98 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70165Bp64Blood pressure QTL 645.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X144812931706553Rat
1298071Edpm12Estrogen-dependent pituitary mass QTL 123.2pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)X292789847927898Rat
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X143491017Rat
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
10755455Coatc13Coat color QTL 130coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7440600049406000Rat
631666Iddm5Insulin dependent diabetes mellitus QTL 5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X449454949494549Rat
634325Bw13Body weight QTL 130body mass (VT:0001259)body weight (CMO:0000012)X144797220991088Rat
631204Gluco15Glucose level QTL 150.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)X162371522646544Rat

Markers in Region
RH131071  
Rat AssemblyChrPosition (strand)SourceJBrowse
RGSC_v3.4X26,988,442 - 26,988,661UniSTSRGSC3.4
CeleraX15,028,145 - 15,028,364UniSTS
RH 3.4 MapX166.4UniSTS
Cytogenetic MapXq13UniSTS
BE115018  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X14,934,574 - 14,934,730 (+)MAPPERmRatBN7.2
Rnor_6.0X15,778,452 - 15,778,607NCBIRnor6.0
Rnor_5.0X16,569,150 - 16,569,305UniSTSRnor5.0
RGSC_v3.4X26,975,894 - 26,976,049UniSTSRGSC3.4
CeleraX15,017,862 - 15,018,017UniSTS
RH 3.4 MapX166.81UniSTS
Cytogenetic MapXq13UniSTS


Expression


Sequence


Ensembl Acc Id: ENSRNOT00000118528   ⟹   ENSRNOP00000092451
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX14,929,323 - 14,945,193 (+)Ensembl
RefSeq Acc Id: NM_001401176   ⟹   NP_001388105
RefSeq Status: INFERRED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X17,601,230 - 17,617,082 (+)NCBI
mRatBN7.2X14,929,344 - 14,945,197 (+)NCBI
RefSeq Acc Id: XM_039100560   ⟹   XP_038956488
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X17,602,304 - 17,617,087 (+)NCBI
mRatBN7.2X14,930,417 - 14,945,249 (+)NCBI
RefSeq Acc Id: XM_063280125   ⟹   XP_063136195
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X17,581,467 - 17,617,087 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001388105 (Get FASTA)   NCBI Sequence Viewer  
  XP_038956488 (Get FASTA)   NCBI Sequence Viewer  
  XP_063136195 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000092451.1
RefSeq Acc Id: XP_038956488   ⟸   XM_039100560
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000092451   ⟸   ENSRNOT00000118528
RefSeq Acc Id: NP_001388105   ⟸   NM_001401176
- UniProtKB: A0A8I6AHW4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136195   ⟸   XM_063280125
- Peptide Label: isoform X2
Protein Domains
CBM21

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-2903 BioCyc
Ensembl Genes ENSRNOG00000068767 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000118528.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.2440 UniProtKB/TrEMBL
InterPro CBM21_dom UniProtKB/TrEMBL
  CBM21_dom_sf UniProtKB/TrEMBL
  PP1_regulatory_subunit_3 UniProtKB/TrEMBL
NCBI Gene 363453 ENTREZGENE
PANTHER PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT UniProtKB/TrEMBL
  PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3F UniProtKB/TrEMBL
Pfam CBM_21 UniProtKB/TrEMBL
PhenoGen Ppp1r3f PhenoGen
PROSITE CBM21 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000068767 RatGTEx
UniProt A0A8I6AHW4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-10 Ppp1r3f  protein phosphatase 1, regulatory subunit 3F  Ppp1r3f  protein phosphatase 1, regulatory (inhibitor) subunit 3F  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 Ppp1r3f  protein phosphatase 1, regulatory (inhibitor) subunit 3F  Ppp1r3f  protein phosphatase 1, regulatory (inhibitor) subunit 3F  Gene reactivated at release of RGSC5.0 assembly 2298974 REACTIVATED
2008-04-30 Ppp1r3f  protein phosphatase 1, regulatory (inhibitor) subunit 3F   Ppp1r3f_predicted  protein phosphatase 1, regulatory (inhibitor) subunit 3F (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Ppp1r3f_predicted  protein phosphatase 1, regulatory (inhibitor) subunit 3F (predicted)  RGD1566398_predicted  similar to DXImx48e protein (predicted)  Symbol and Name updated 1299863 APPROVED
2006-03-07 RGD1566398_predicted  similar to DXImx48e protein (predicted)  LOC363453  similar to DXImx48e protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC363453  similar to DXImx48e protein      Symbol and Name status set to provisional 70820 PROVISIONAL