Med14 (mediator complex subunit 14) - Rat Genome Database
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Gene: Med14 (mediator complex subunit 14) Rattus norvegicus
Analyze
Symbol: Med14
Name: mediator complex subunit 14
RGD ID: 1560170
Description: Predicted to have transcription coactivator activity. Predicted to be involved in positive regulation of transcription initiation from RNA polymerase II promoter and stem cell population maintenance. Predicted to localize to mediator complex. Orthologous to human MED14 (mediator complex subunit 14); PARTICIPATES IN cortisol signaling pathway; RNA polymerase II transcription pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; (+)-catechin (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC317343; mediator of RNA polymerase II transcription subunit 14; RGD1560170; similar to cofactor required for Sp1 transcriptional activation, subunit 2, 150kDa
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Med14-ps1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X10,036,749 - 10,127,910 (+)NCBI
Rnor_6.0 EnsemblX10,963,809 - 11,082,565 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X10,964,035 - 11,082,403 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X11,762,671 - 11,880,963 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X22,116,986 - 22,205,877 (+)NCBIRGSC3.4rn4RGSC3.4
CeleraX10,562,309 - 10,650,954 (+)NCBICelera
Cytogenetic MapXq12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:10198638   PMID:10235267   PMID:11867769   PMID:12037571   PMID:12218053   PMID:15340084   PMID:15632090   PMID:19946888   PMID:20508642   PMID:20720539  


Genomics

Comparative Map Data
Med14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X10,036,749 - 10,127,910 (+)NCBI
Rnor_6.0 EnsemblX10,963,809 - 11,082,565 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X10,964,035 - 11,082,403 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X11,762,671 - 11,880,963 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X22,116,986 - 22,205,877 (+)NCBIRGSC3.4rn4RGSC3.4
CeleraX10,562,309 - 10,650,954 (+)NCBICelera
Cytogenetic MapXq12NCBI
MED14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX40,648,305 - 40,735,858 (-)EnsemblGRCh38hg38GRCh38
GRCh38X40,648,305 - 40,736,122 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X40,507,557 - 40,594,794 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X40,393,739 - 40,479,748 (-)NCBINCBI36hg18NCBI36
Build 34X40,263,811 - 40,351,037NCBI
CeleraX44,649,421 - 44,734,350 (-)NCBI
Cytogenetic MapXp11.4NCBI
HuRefX38,238,905 - 38,324,580 (-)NCBIHuRef
CHM1_1X40,540,939 - 40,626,911 (-)NCBICHM1_1
Med14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X12,541,607 - 12,628,813 (-)NCBIGRCm39mm39
GRCm39 EnsemblX12,541,608 - 12,628,312 (-)Ensembl
GRCm38X12,675,368 - 12,762,594 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX12,675,369 - 12,762,073 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X12,252,497 - 12,339,099 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X11,836,708 - 11,919,032 (-)NCBImm8
CeleraX10,369,353 - 10,456,055 (-)NCBICelera
Cytogenetic MapXA1.1NCBI
Med14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555651,888,443 - 1,959,141 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555651,888,442 - 1,959,141 (+)NCBIChiLan1.0ChiLan1.0
MED14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X40,800,526 - 40,886,291 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX40,798,363 - 40,886,270 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X33,097,206 - 33,183,322 (-)NCBIMhudiblu_PPA_v0panPan3
MED14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 EnsemblX35,125,774 - 35,191,122 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1X35,125,270 - 35,191,260 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Med14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365027,280,606 - 7,350,750 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MED14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX36,354,061 - 36,424,715 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X36,354,057 - 36,424,837 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X40,452,288 - 40,523,049 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MED14
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X37,810,996 - 37,898,114 (-)NCBI
ChlSab1.1 EnsemblX37,810,710 - 37,897,929 (-)Ensembl
Med14
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476214,832,485 - 14,903,119 (+)NCBI

Position Markers
DXS7582  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0X11,078,007 - 11,078,120NCBIRnor6.0
Rnor_5.0X11,876,564 - 11,876,677UniSTSRnor5.0
RGSC_v3.4X22,203,013 - 22,203,126UniSTSRGSC3.4
CeleraX10,648,066 - 10,648,179UniSTS
Cytogenetic MapXq13UniSTS
RH127471  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0X11,082,221 - 11,082,423NCBIRnor6.0
Rnor_5.0X11,880,778 - 11,880,980UniSTSRnor5.0
RGSC_v3.4X22,207,227 - 22,207,429UniSTSRGSC3.4
CeleraX10,652,280 - 10,652,482UniSTS
RH 3.4 MapX30.4UniSTS
Cytogenetic MapXq13UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631204Gluco15Glucose level QTL 150.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)X183816624331837Rat
70165Bp64Blood pressure QTL 645.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X166260933443848Rat
70166Bp65Blood pressure QTL 655.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X166245312370298Rat
1298071Edpm12Estrogen-dependent pituitary mass QTL 123.2pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)X428214049282140Rat
631666Iddm5Insulin dependent diabetes mellitus QTL 5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X595407850954078Rat
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X144092703Rat
634325Bw13Body weight QTL 130body mass (VT:0001259)body weight (CMO:0000012)X166245321592783Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:95
Count of miRNA genes:81
Interacting mature miRNAs:82
Transcripts:ENSRNOT00000066480
Prediction methods:Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 21 36 20 19 20 2 2 74 29 34 11 2
Low 22 21 21 21 6 9 6 7 6
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000066480   ⟹   ENSRNOP00000063505
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX10,964,187 - 11,080,871 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000093176   ⟹   ENSRNOP00000076161
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX10,963,809 - 11,078,188 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000093181   ⟹   ENSRNOP00000076132
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX10,964,067 - 11,082,565 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000093346
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX10,964,056 - 11,044,319 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000093450
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX10,964,215 - 11,023,876 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000093665   ⟹   ENSRNOP00000076292
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX11,050,121 - 11,077,448 (+)Ensembl
RefSeq Acc Id: NM_001191727   ⟹   NP_001178656
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X10,036,984 - 10,126,240 (+)NCBI
Rnor_6.0X10,964,035 - 11,080,895 (+)NCBI
Rnor_5.0X11,762,671 - 11,880,963 (+)NCBI
CeleraX10,562,309 - 10,650,954 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017602059   ⟹   XP_017457548
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X10,998,493 - 11,082,403 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017602060   ⟹   XP_017457549
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X10,998,493 - 11,082,403 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039099757   ⟹   XP_038955685
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X10,036,749 - 10,127,910 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001178656 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955685 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL97637 (Get FASTA)   NCBI Sequence Viewer  
  EDL97638 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001178656   ⟸   NM_001191727
- UniProtKB: D4A020 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017457548   ⟸   XM_017602059
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017457549   ⟸   XM_017602060
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000076292   ⟸   ENSRNOT00000093665
RefSeq Acc Id: ENSRNOP00000063505   ⟸   ENSRNOT00000066480
RefSeq Acc Id: ENSRNOP00000076132   ⟸   ENSRNOT00000093181
RefSeq Acc Id: ENSRNOP00000076161   ⟸   ENSRNOT00000093176
RefSeq Acc Id: XP_038955685   ⟸   XM_039099757
- Peptide Label: isoform X1

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701719
Promoter ID:EPDNEW_R12234
Type:multiple initiation site
Name:Med14_2
Description:mediator complex subunit 14
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R12235  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X10,963,854 - 10,963,914EPDNEW
RGD ID:13701712
Promoter ID:EPDNEW_R12235
Type:initiation region
Name:Med14_1
Description:mediator complex subunit 14
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R12234  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X10,964,089 - 10,964,149EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560170 AgrOrtholog
Ensembl Genes ENSRNOG00000003792 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000063505 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000076132 UniProtKB/TrEMBL
  ENSRNOP00000076161 UniProtKB/TrEMBL
  ENSRNOP00000076292 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000066480 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000093176 UniProtKB/TrEMBL
  ENSRNOT00000093181 UniProtKB/TrEMBL
  ENSRNOT00000093665 UniProtKB/TrEMBL
InterPro Mediator_Med14 UniProtKB/TrEMBL
KEGG Report rno:317343 UniProtKB/TrEMBL
NCBI Gene 317343 ENTREZGENE
PANTHER PTHR12809 UniProtKB/TrEMBL
Pfam MED14 UniProtKB/TrEMBL
PhenoGen Med14 PhenoGen
UniProt A0A1W2Q682_RAT UniProtKB/TrEMBL
  A0A1W2Q6L0_RAT UniProtKB/TrEMBL
  D4A020 ENTREZGENE, UniProtKB/TrEMBL
  W8C3Y3_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-28 Med14  mediator complex subunit 14  RGD1560170_predicted  similar to cofactor required for Sp1 transcriptional activation, subunit 2, 150kDa (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1560170_predicted  similar to cofactor required for Sp1 transcriptional activation, subunit 2, 150kDa (predicted)  LOC317343  similar to cofactor required for Sp1 transcriptional activation, subunit 2, 150kDa  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC317343  similar to cofactor required for Sp1 transcriptional activation, subunit 2, 150kDa      Symbol and Name status set to provisional 70820 PROVISIONAL