Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Phf8 (PHD finger protein 8) Rattus norvegicus
Analyze
Symbol: Phf8
Name: PHD finger protein 8
RGD ID: 1561065
Description: Predicted to have several functions, including histone demethylase activity; methylated histone binding activity; and transition metal ion binding activity. Predicted to be involved in G1/S transition of mitotic cell cycle; histone lysine demethylation; and positive regulation of transcription, DNA-templated. Predicted to localize to nuclear membrane; nucleolus; and nucleoplasm. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Siderius type. Orthologous to human PHF8 (PHD finger protein 8); PARTICIPATES IN histone modification pathway; INTERACTS WITH acrylamide; atrazine; thioacetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: histone lysine demethylase PHF8; hypothetical protein LOC317425; LOC317425; RGD1561065; similar to mKIAA1111 protein; uncharacterized protein LOC317425
Orthologs:
Homo sapiens (human) : PHF8 (PHD finger protein 8)  HGNC  Alliance
Mus musculus (house mouse) : Phf8 (PHD finger protein 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Phf8 (PHD finger protein 8)
Pan paniscus (bonobo/pygmy chimpanzee) : PHF8 (PHD finger protein 8)
Canis lupus familiaris (dog) : PHF8 (PHD finger protein 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Phf8 (PHD finger protein 8)
Sus scrofa (pig) : PHF8 (PHD finger protein 8)
Chlorocebus sabaeus (African green monkey) : PHF8 (PHD finger protein 8)
Heterocephalus glaber (naked mole-rat) : Phf8 (PHD finger protein 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X21,063,487 - 21,168,750 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX21,063,562 - 21,168,750 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X22,281,640 - 22,387,057 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X40,869,942 - 40,970,244 (+)NCBIRGSC3.4rn4RGSC3.4
CeleraX20,777,198 - 20,875,387 (+)NCBICelera
Cytogenetic MapXq12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Phf8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1561065
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.