Gene: Ace2 (angiotensin I converting enzyme 2) Rattus norvegicus
Symbol: Ace2
Name: angiotensin I converting enzyme 2
Description: ENCODES a protein that exhibits carboxypeptidase activity; endopeptidase activity (ortholog); metallocarboxypeptidase activity (ortholog); INVOLVED IN maternal process involved in female pregnancy; negative regulation of ERK1 and ERK2 cascade; negative regulation of smooth muscle cell proliferation; PARTICIPATES IN renin-angiotensin cascade pathway; ASSOCIATED WITH Cardiac Fibrosis; diabetes mellitus, experimental; Diabetic Cardiomyopathies; FOUND IN extracellular space; membrane; cell surface (ortholog); INTERACTS WITH 3-chloropropane-1,2-diol; 4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile; aflatoxin B1
Type: protein-coding
Also known as: ACE-related carboxypeptidase; angiotensin I converting enzyme (peptidyl-dipeptidase A) 2; angiotensin-converting enzyme 2; anigotensin-converting enzyme-related carboxypeptidase; renal angiotensin-converting enzyme 2
Homo sapiens (human) : ACE2 (angiotensin I converting enzyme 2)  HGNC  Alliance
Mus musculus (house mouse) : Ace2 (angiotensin I converting enzyme (peptidyl-dipeptidase A) 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ace2 (angiotensin I converting enzyme 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ACE2 (angiotensin I converting enzyme 2)
Canis lupus familiaris (dog) : ACE2 (angiotensin I converting enzyme 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ace2 (angiotensin I converting enzyme 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0X32,050,734 - 32,095,860 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X32,422,286 - 32,469,137 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X51,051,758 - 51,096,036 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X51,105,228 - 51,149,505 (-)NCBI
CeleraX30,638,123 - 30,683,403 (-)NCBICelera
Cytogenetic MapXq14NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Protein Structures

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Ace2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 728890
Created: 2003-11-21
Species: Rattus norvegicus
Last Modified: 2018-03-20
Status: ACTIVE