Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17beta-estradiol | multiple interactions | ISO | TRO (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of TRO mRNA | CTD | PMID:30165855 | 2-methylcholine | affects expression | ISO | TRO (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of TRO mRNA | CTD | PMID:21179406 | all-trans-retinoic acid | increases expression | ISO | TRO (Homo sapiens) | 6480464 | Tretinoin results in increased expression of TRO mRNA | CTD | PMID:23830798 | antirheumatic drug | increases expression | ISO | TRO (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of TRO mRNA | CTD | PMID:24449571 | arsenite(3-) | multiple interactions | ISO | Tro (Mus musculus) | 6480464 | TRP53 protein affects the reaction [arsenite results in decreased expression of TRO mRNA] | CTD | PMID:18929588 | arsenite(3-) | decreases expression | ISO | Tro (Mus musculus) | 6480464 | arsenite results in decreased expression of TRO mRNA | CTD | PMID:18929588 | benzo[a]pyrene | increases expression | ISO | Tro (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of TRO mRNA | CTD | PMID:21569818 | benzo[a]pyrene | increases methylation | ISO | TRO (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of TRO 5' UTR | CTD | PMID:27901495 | bis(2-chloroethyl) sulfide | increases expression | ISO | Tro (Mus musculus) | 6480464 | Mustard Gas results in increased expression of TRO mRNA | CTD | PMID:15674844 | bisphenol A | decreases expression | ISO | Tro (Mus musculus) | 6480464 | bisphenol A results in decreased expression of TRO mRNA and bisphenol A results in decreased expression of TRO protein | CTD | PMID:26884915 and PMID:32156529 | buta-1,3-diene | increases expression | ISO | Tro (Mus musculus) | 6480464 | 1 and 3-butadiene results in increased expression of TRO mRNA | CTD | PMID:29038090 | butanal | increases expression | ISO | TRO (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of TRO mRNA | CTD | PMID:26079696 | cadmium atom | multiple interactions | ISO | TRO (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TRO mRNA | CTD | PMID:35301059 | cadmium atom | multiple interactions | ISO | Tro (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TRO mRNA | CTD | PMID:37325564 | cadmium dichloride | multiple interactions | ISO | TRO (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TRO mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | ISO | Tro (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TRO mRNA | CTD | PMID:37325564 | choline | multiple interactions | ISO | Tro (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TRO mRNA | CTD | PMID:20938992 | copper(II) sulfate | decreases expression | ISO | TRO (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of TRO mRNA | CTD | PMID:19549813 | cyclosporin A | decreases expression | ISO | TRO (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of TRO mRNA | CTD | PMID:25562108 | dexamethasone | decreases expression | ISO | TRO (Homo sapiens) | 6480464 | Dexamethasone results in decreased expression of TRO mRNA | CTD | PMID:25047013 | diquat | decreases expression | ISO | Tro (Mus musculus) | 6480464 | Diquat results in decreased expression of TRO mRNA | CTD | PMID:36851058 | dorsomorphin | multiple interactions | ISO | TRO (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TRO mRNA | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | TRO (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of TRO mRNA | CTD | PMID:29803840 | elemental selenium | increases expression | ISO | TRO (Homo sapiens) | 6480464 | Selenium results in increased expression of TRO mRNA | CTD | PMID:19244175 | epoxiconazole | increases expression | ISO | Tro (Mus musculus) | 6480464 | epoxiconazole results in increased expression of TRO mRNA | CTD | PMID:35436446 | folic acid | multiple interactions | ISO | Tro (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TRO mRNA | CTD | PMID:20938992 | glyphosate | increases expression | ISO | Tro (Mus musculus) | 6480464 | Glyphosate results in increased expression of TRO mRNA | CTD | PMID:35897073 | hydrogen peroxide | affects expression | ISO | TRO (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of TRO mRNA | CTD | PMID:21179406 | L-methionine | multiple interactions | ISO | Tro (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TRO mRNA | CTD | PMID:20938992 | maneb | multiple interactions | ISO | Tro (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of TRO mRNA | CTD | PMID:36117858 | nickel sulfate | increases expression | ISO | TRO (Homo sapiens) | 6480464 | nickel sulfate results in increased expression of TRO mRNA | CTD | PMID:22714537 | p-chloromercuribenzoic acid | increases expression | ISO | TRO (Homo sapiens) | 6480464 | p-Chloromercuribenzoic Acid results in increased expression of TRO mRNA | CTD | PMID:26272509 | p-chloromercuribenzoic acid | multiple interactions | ISO | TRO (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TRO mRNA | CTD | PMID:27188386 | paracetamol | decreases expression | ISO | TRO (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of TRO mRNA | CTD | PMID:26690555 | paraquat | multiple interactions | ISO | Tro (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of TRO mRNA | CTD | PMID:36117858 | pentanal | increases expression | ISO | TRO (Homo sapiens) | 6480464 | pentanal results in increased expression of TRO mRNA | CTD | PMID:26079696 | propanal | increases expression | ISO | TRO (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of TRO mRNA | CTD | PMID:26079696 | rotenone | increases expression | ISO | TRO (Homo sapiens) | 6480464 | Rotenone results in increased expression of TRO mRNA | CTD | PMID:29955902 | SB 431542 | multiple interactions | ISO | TRO (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TRO mRNA | CTD | PMID:27188386 | selenium atom | increases expression | ISO | TRO (Homo sapiens) | 6480464 | Selenium results in increased expression of TRO mRNA | CTD | PMID:19244175 | silicon dioxide | decreases expression | ISO | TRO (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of TRO mRNA | CTD | PMID:25895662 | silicon dioxide | increases expression | ISO | TRO (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of TRO mRNA | CTD | PMID:23806026 | sodium arsenite | increases expression | ISO | TRO (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of TRO mRNA | CTD | PMID:22714537 | sunitinib | decreases expression | ISO | TRO (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of TRO mRNA | CTD | PMID:31533062 | titanium dioxide | decreases expression | ISO | Tro (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of TRO mRNA | CTD | PMID:29264374 | tris(2-butoxyethyl) phosphate | affects expression | ISO | TRO (Homo sapiens) | 6480464 | tris(2-butoxyethyl) phosphate affects the expression of TRO mRNA | CTD | PMID:29024780 | valproic acid | affects expression | ISO | TRO (Homo sapiens) | 6480464 | Valproic Acid affects the expression of TRO mRNA | CTD | PMID:25979313 | valproic acid | decreases expression | ISO | TRO (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of TRO mRNA | CTD | PMID:23179753 | vitamin E | increases expression | ISO | TRO (Homo sapiens) | 6480464 | Vitamin E results in increased expression of TRO mRNA | CTD | PMID:19244175 | |