Gene: Atp6ap2 (ATPase H+ transporting accessory protein 2) Rattus norvegicus
Analyze
Symbol:
Atp6ap2
Name:
ATPase H+ transporting accessory protein 2
RGD ID:
1561269
Description:
Predicted to have signaling receptor activity. Predicted to be involved in several processes, including angiotensin maturation; lysosomal lumen acidification; and regulation of signal transduction. Localizes to several cellular components, including apical plasma membrane; cell body; and extracellular space. Biomarker of hypertension. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type II and syndromic X-linked intellectual disability Hedera type. Orthologous to human ATP6AP2 (ATPase H+ transporting accessory protein 2); PARTICIPATES IN renin-angiotensin cascade pathway; INTERACTS WITH 2,6-dinitrotoluene; 3-chloropropane-1,2-diol; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
ATPase H(+)-transporting lysosomal-interacting protein 2; ATPase, H(+)-transporting, lysosomal-interacting protein 2; ATPase, H+ transporting, lysosomal accessory protein 2; MGC94783; renin receptor; renin/prorenin receptor
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
ATP6AP2 (ATPase H+ transporting accessory protein 2) HGNC
EggNOG, Ensembl, HomoloGene, NCBI, OMA, OrthoDB, OrthoMCL, PhylomeDB, Treefam
Mus musculus (house mouse):
Atp6ap2 (ATPase, H+ transporting, lysosomal accessory protein 2) HGNC
Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Atp6ap2 (ATPase H+ transporting accessory protein 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
ATP6AP2 (ATPase H+ transporting accessory protein 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
ATP6AP2 (ATPase H+ transporting accessory protein 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Atp6ap2 (ATPase H+ transporting accessory protein 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
ATP6AP2 (ATPase H+ transporting accessory protein 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):
ATP6AP2 (ATPase H+ transporting accessory protein 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Atp6ap2 (ATPase H+ transporting accessory protein 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
ATP6AP2 (ATPase H+ transporting accessory protein 2)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Mus musculus (house mouse):
Atp6ap2 (ATPase, H+ transporting, lysosomal accessory protein 2)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Danio rerio (zebrafish):
atp6ap2 (ATPase H+ transporting accessory protein 2)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Drosophila melanogaster (fruit fly):
ATP6AP2
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Caenorhabditis elegans (roundworm):
vha-20
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB)
Caenorhabditis elegans (roundworm):
T14B4.3
Alliance
DIOPT (Ensembl Compara|OrthoFinder|PANTHER|TreeFam)
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Rnor_6.0 X 11,137,889 - 11,164,854 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl X 11,136,939 - 11,164,915 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 X 11,936,459 - 11,963,424 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 X 22,264,078 - 22,291,988 (-) NCBI RGSC3.4 rn4 RGSC3.4 Celera X 10,708,369 - 10,735,267 (-) NCBI Celera Cytogenetic Map X q12 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Annotations - ClinVar
autistic disorder ISO RGD:1346001 8554872 ClinVar Annotator: match by term: Autistic disorder of childhood onset ClinVar PMID:21681106 , PMID:30208311 Congenital Disorder of Glycosylation Type IIr ISO RGD:1346001 8554872 ClinVar Annotator: match by term: CONGENITAL DISORDER OF GLYCOSYLATION, TYPE IIr ClinVar PMID:29127204 Neurodevelopmental Disorders ISO RGD:1346001 8554872 ClinVar Annotator: match by term: Neurodevelopmental disorder ClinVar PMID:25741868 ornithine carbamoyltransferase deficiency ISO RGD:1346001 8554872 ClinVar Annotator: match by term: Ornithine carbamoyltransferase deficiency ClinVar PMID:11793468 more ... syndromic X-linked intellectual disability Hedera type ISO RGD:1346001 8554872 ClinVar Annotator: match by term: Mental retardation, X-linked, syndromic, Hedera type ClinVar PMID:25741868 , PMID:28492532 syndromic X-linked intellectual disability Hedera type ISO RGD:1346001 8554872 ClinVar Annotator: match by term: Mental retardation, X-linked, syndromic, Hedera type ClinVar PMID:11782983 more ... syndromic X-linked intellectual disability Hedera type ISO RGD:1346001 8554872 ClinVar Annotator: match by term: Mental retardation, X-linked, syndromic, Hedera type ClinVar PMID:26467025 , PMID:28492532 syndromic X-linked intellectual disability Hedera type ISO RGD:1346001 8554872 ClinVar Annotator: match by term: Mental retardation, X-linked, syndromic, Hedera type ClinVar PMID:30985297 syndromic X-linked intellectual disability Hedera type ISO RGD:1346001 8554872 ClinVar Annotator: match by OMIM:300423 ClinVar PMID:26467484 syndromic X-linked intellectual disability Hedera type ISO RGD:1346001 8554872 ClinVar Annotator: match by term: Mental retardation, X-linked, syndromic, Hedera type ClinVar PMID:28492532 syndromic X-linked intellectual disability Lubs type ISO RGD:1346001 8554872 ClinVar Annotator: match by term: MECP2 duplication syndrome ClinVar PMID:25741868 X-linked parkinsonism-spasticity syndrome ISO RGD:1346001 8554872 ClinVar Annotator: match by OMIM:300911 ClinVar PMID:20629132 , PMID:23595882
Imported Annotations - CTD
Craniofacial Abnormalities ISO RGD:1346001 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:16759393 Fibrosis ISO RGD:1346001 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:21795644 Imported Annotations - OMIM
Congenital Disorder of Glycosylation Type IIr ISO RGD:1346001 7240710 OMIM syndromic X-linked intellectual disability Hedera type ISO RGD:1346001 7240710 OMIM X-linked parkinsonism-spasticity syndrome ISO RGD:1346001 7240710 OMIM
1,2-dimethylhydrazine multiple interactions ISO RGD:1557796 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP6AP2 mRNA CTD PMID:22206623 2,3',4,4',5-Pentachlorobiphenyl increases expression ISO RGD:1557796 6480464 2 more ... CTD PMID:31388691 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1557796 6480464 Tetrachlorodibenzodioxin affects the expression of ATP6AP2 mRNA CTD PMID:21570461 , PMID:24680724 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of ATP6AP2 mRNA CTD PMID:21346803 2-hydroxypropanoic acid decreases expression ISO RGD:1346001 6480464 Lactic Acid results in decreased expression of ATP6AP2 mRNA CTD PMID:30851411 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of ATP6AP2 mRNA CTD PMID:28522335 4,4'-diaminodiphenylmethane increases expression ISO RGD:1557796 6480464 4, 4'-diaminodiphenylmethane results in increased expression of ATP6AP2 mRNA CTD PMID:18648102 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole affects expression EXP 6480464 Omeprazole affects the expression of ATP6AP2 mRNA CTD PMID:19483382 6-propyl-2-thiouracil affects expression EXP 6480464 Propylthiouracil affects the expression of ATP6AP2 mRNA CTD PMID:19483382 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of ATP6AP2 mRNA CTD PMID:24780913 7,12-dimethyltetraphene affects expression ISO RGD:1557796 6480464 9 more ... CTD PMID:21785161 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of ATP6AP2 mRNA CTD PMID:28959563 aflatoxin B1 increases expression ISO RGD:1346001 6480464 Aflatoxin B1 results in increased expression of ATP6AP2 mRNA CTD PMID:21641981 aldehydo-D-glucose multiple interactions EXP 6480464 N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Glucose results in increased expression of ATP6AP2 mRNA], N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Glucose results in increased expression of ATP6AP2 protein] CTD PMID:19861503 aldehydo-D-glucose increases expression EXP 6480464 Glucose results in increased expression of ATP6AP2 mRNA, Glucose results in increased expression of ATP6AP2 protein CTD PMID:19861503 amiodarone affects expression EXP 6480464 Amiodarone affects the expression of ATP6AP2 mRNA CTD PMID:19483382 amphetamine increases expression EXP 6480464 Amphetamine results in increased expression of ATP6AP2 mRNA CTD PMID:30779732 arsenite(3-) increases methylation ISO RGD:1346001 6480464 arsenite results in increased methylation of ATP6AP2 promoter CTD PMID:23974009 auramine O increases expression ISO RGD:1346001 6480464 Benzophenoneidum results in increased expression of ATP6AP2 protein CTD PMID:28722353 benzbromarone affects expression EXP 6480464 Benzbromarone affects the expression of ATP6AP2 mRNA CTD PMID:19483382 benzo[a]pyrene affects expression ISO RGD:1557796 6480464 Benzo(a)pyrene affects the expression of ATP6AP2 mRNA CTD PMID:22342234 benzo[a]pyrene affects methylation ISO RGD:1346001 6480464 Benzo(a)pyrene affects the methylation of ATP6AP2 promoter CTD PMID:27901495 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of ATP6AP2 mRNA CTD PMID:25181051 C60 fullerene affects expression EXP 6480464 fullerene C60 affects the expression of ATP6AP2 mRNA CTD PMID:19167457 cadmium dichloride increases expression ISO RGD:1557796 6480464 Cadmium Chloride results in increased expression of ATP6AP2 mRNA CTD PMID:30030080 carbon nanotube increases expression ISO RGD:1557796 6480464 Nanotubes, Carbon analog results in increased expression of ATP6AP2 mRNA CTD PMID:25554681 celecoxib affects expression ISO RGD:1557796 6480464 Celecoxib affects the expression of ATP6AP2 mRNA CTD PMID:20562220 chlordecone increases expression ISO RGD:1557796 6480464 Chlordecone results in increased expression of ATP6AP2 mRNA CTD PMID:29980752 chloropicrin affects expression ISO RGD:1346001 6480464 chloropicrin affects the expression of ATP6AP2 mRNA CTD PMID:26352163 cisplatin affects response to substance ISO RGD:1346001 6480464 ATP6AP2 mRNA affects the susceptibility to Cisplatin CTD PMID:18610736 cisplatin increases expression ISO RGD:1346001 6480464 Cisplatin results in increased expression of ATP6AP2 mRNA CTD PMID:27392435 clofibrate affects expression EXP 6480464 Clofibrate affects the expression of ATP6AP2 mRNA CTD PMID:19483382 cobalt dichloride increases expression ISO RGD:1346001 6480464 cobaltous chloride results in increased expression of ATP6AP2 mRNA CTD PMID:19376846 copper atom multiple interactions ISO RGD:1557796 6480464 MT1 affects the reaction [Copper results in increased expression of ATP6AP2 mRNA], MT2 affects the reaction [Copper results in increased expression of ATP6AP2 mRNA] CTD PMID:16629173 copper(0) multiple interactions ISO RGD:1557796 6480464 MT1 affects the reaction [Copper results in increased expression of ATP6AP2 mRNA], MT2 affects the reaction [Copper results in increased expression of ATP6AP2 mRNA] CTD PMID:16629173 D-glucose increases expression EXP 6480464 Glucose results in increased expression of ATP6AP2 mRNA, Glucose results in increased expression of ATP6AP2 protein CTD PMID:19861503 D-glucose multiple interactions EXP 6480464 N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Glucose results in increased expression of ATP6AP2 mRNA], N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Glucose results in increased expression of ATP6AP2 protein] CTD PMID:19861503 decabromodiphenyl ether decreases expression EXP 6480464 decabromobiphenyl ether results in decreased expression of ATP6AP2 mRNA CTD PMID:23914054 dexamethasone decreases expression ISO RGD:1346001 6480464 Dexamethasone results in decreased expression of ATP6AP2 mRNA CTD PMID:19853017 dicrotophos decreases expression ISO RGD:1346001 6480464 dicrotophos results in decreased expression of ATP6AP2 mRNA CTD PMID:28302478 doxorubicin increases expression ISO RGD:1346001 6480464 Doxorubicin results in increased expression of ATP6AP2 mRNA CTD PMID:29803840 ethanol affects splicing ISO RGD:1557796 6480464 Ethanol affects the splicing of ATP6AP2 mRNA CTD PMID:30319688 ethyl methanesulfonate increases expression ISO RGD:1346001 6480464 Ethyl Methanesulfonate results in increased expression of ATP6AP2 mRNA CTD PMID:23649840 finasteride increases expression EXP 6480464 Finasteride results in increased expression of ATP6AP2 mRNA CTD PMID:24136188 flutamide increases expression EXP 6480464 Flutamide results in increased expression of ATP6AP2 mRNA CTD PMID:24136188 folic acid multiple interactions ISO RGD:1557796 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATP6AP2 mRNA CTD PMID:22206623 formaldehyde increases expression ISO RGD:1346001 6480464 Formaldehyde results in increased expression of ATP6AP2 mRNA CTD PMID:23649840 glucose increases expression EXP 6480464 Glucose results in increased expression of ATP6AP2 mRNA, Glucose results in increased expression of ATP6AP2 protein CTD PMID:19861503 glucose multiple interactions EXP 6480464 N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Glucose results in increased expression of ATP6AP2 mRNA], N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Glucose results in increased expression of ATP6AP2 protein] CTD PMID:19861503 L-ethionine affects expression EXP 6480464 Ethionine affects the expression of ATP6AP2 mRNA CTD PMID:19483382 lead(0) decreases expression ISO RGD:1346001 6480464 Lead results in decreased expression of ATP6AP2 mRNA CTD PMID:19921347 lead(0) affects expression ISO RGD:1346001 6480464 Lead affects the expression of ATP6AP2 mRNA CTD PMID:28903495 lead(2+) decreases expression ISO RGD:1346001 6480464 Lead results in decreased expression of ATP6AP2 mRNA CTD PMID:19921347 lead(2+) affects expression ISO RGD:1346001 6480464 Lead affects the expression of ATP6AP2 mRNA CTD PMID:28903495 leflunomide increases expression EXP 6480464 leflunomide results in increased expression of ATP6AP2 mRNA CTD PMID:24136188 methyl methanesulfonate increases expression ISO RGD:1346001 6480464 Methyl Methanesulfonate results in increased expression of ATP6AP2 mRNA CTD PMID:23649840 nefazodone increases expression EXP 6480464 nefazodone results in increased expression of ATP6AP2 mRNA CTD PMID:24136188 nimesulide increases expression EXP 6480464 nimesulide results in increased expression of ATP6AP2 mRNA CTD PMID:24136188 NS-398 multiple interactions EXP 6480464 N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Glucose results in increased expression of ATP6AP2 mRNA], N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Glucose results in increased expression of ATP6AP2 protein] CTD PMID:19861503 omeprazole affects expression EXP 6480464 Omeprazole affects the expression of ATP6AP2 mRNA CTD PMID:19483382 paracetamol increases expression ISO RGD:1346001 6480464 Acetaminophen results in increased expression of ATP6AP2 mRNA CTD PMID:22230336 perfluorooctanoic acid decreases expression ISO RGD:1346001 6480464 perfluorooctanoic acid results in decreased expression of ATP6AP2 protein CTD PMID:26879310 pirinixic acid affects expression EXP 6480464 pirinixic acid affects the expression of ATP6AP2 mRNA CTD PMID:19483382 potassium chromate decreases expression ISO RGD:1346001 6480464 potassium chromate(VI) results in decreased expression of ATP6AP2 mRNA CTD PMID:22714537 rac-lactic acid decreases expression ISO RGD:1346001 6480464 Lactic Acid results in decreased expression of ATP6AP2 mRNA CTD PMID:30851411 silicon dioxide decreases expression ISO RGD:1346001 6480464 Silicon Dioxide analog results in decreased expression of ATP6AP2 mRNA CTD PMID:25895662 silver atom decreases expression ISO RGD:1557796 6480464 Silver results in decreased expression of ATP6AP2 mRNA CTD PMID:27131904 silver(0) decreases expression ISO RGD:1557796 6480464 Silver results in decreased expression of ATP6AP2 mRNA CTD PMID:27131904 streptozocin multiple interactions EXP 6480464 (3 more ... CTD PMID:18192338 streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of ATP6AP2 mRNA, Streptozocin results in increased expression of ATP6AP2 protein CTD PMID:18192338 sunitinib increases expression ISO RGD:1346001 6480464 Sunitinib results in increased expression of ATP6AP2 mRNA CTD PMID:31533062 tetrachloromethane increases expression ISO RGD:1557796 6480464 Carbon Tetrachloride results in increased expression of ATP6AP2 mRNA CTD PMID:27339419 , PMID:31919559 thioacetamide affects expression EXP 6480464 Thioacetamide affects the expression of ATP6AP2 mRNA CTD PMID:19483382 trichostatin A affects expression ISO RGD:1346001 6480464 trichostatin A affects the expression of ATP6AP2 mRNA CTD PMID:28542535 valproic acid affects expression ISO RGD:1346001 6480464 Valproic Acid affects the expression of ATP6AP2 mRNA CTD PMID:25979313 valproic acid affects methylation ISO RGD:1346001 6480464 Valproic Acid affects the methylation of ATP6AP2 gene CTD PMID:29501571 valproic acid increases expression ISO RGD:1346001 6480464 Valproic Acid results in increased expression of ATP6AP2 mRNA CTD PMID:23179753 more ... valsartan multiple interactions EXP 6480464 Valsartan inhibits the reaction [Streptozocin results in increased expression of ATP6AP2 mRNA], Valsartan inhibits the reaction [Streptozocin results in increased expression of ATP6AP2 protein] CTD PMID:18192338 vanadium atom increases expression ISO RGD:1346001 6480464 Vanadium results in increased expression of ATP6AP2 mRNA CTD PMID:19000753 vanadium(0) increases expression ISO RGD:1346001 6480464 Vanadium results in increased expression of ATP6AP2 mRNA CTD PMID:19000753 vitamin E decreases expression ISO RGD:1346001 6480464 Vitamin E results in decreased expression of ATP6AP2 mRNA CTD PMID:19244175
Biological Process angiotensin maturation ISO RGD:1346001 1624291 (PMID:12045255), (PMID:15746149) RGD PMID:12045255 , PMID:15746149 biological_process ND 1598407 20061210: no relevant rat data RGD central nervous system maturation ISO RGD:1346001 1624291 (PMID:30985297) RGD PMID:30985297 central nervous system maturation ISO RGD:1557796 1624291 (MGI:6467701, PMID:30985297) RGD MGI:6467701 , PMID:30985297 central nervous system maturation ISS UniProtKB:O75787 1600115 GO_REF:0000024 UniProt GO_REF:0000024 eye pigmentation ISO RGD:1346001 1624291 (PMID:20093472) RGD PMID:20093472 head morphogenesis ISO RGD:1346001 1624291 (PMID:20093472) RGD PMID:20093472 lysosomal lumen acidification ISO RGD:1346001 1624291 (PMID:32276428) RGD PMID:32276428 lysosomal lumen acidification ISS UniProtKB:O75787 1600115 GO_REF:0000024 UniProt GO_REF:0000024 positive regulation of canonical Wnt signaling pathway ISO RGD:1346001 1624291 (PMID:30374053) RGD PMID:30374053 positive regulation of canonical Wnt signaling pathway ISS UniProtKB:O75787 1600115 GO_REF:0000024 UniProt GO_REF:0000024 positive regulation of transforming growth factor beta1 production ISO RGD:1346001 1624291 (PMID:16374430) RGD PMID:16374430 positive regulation of Wnt signaling pathway ISO RGD:1346001 1624291 (PMID:20093472) RGD PMID:20093472 positive regulation of Wnt signaling pathway ISO RGD:1557796 1624291 (MGI:4421218, PMID:20093472) RGD MGI:4421218 , PMID:20093472 positive regulation of Wnt signaling pathway IBA MGI:MGI:1917745 more ... 13792537 PMID:21873635 GO_Central regulation of MAPK cascade ISO RGD:1346001 1624291 (PMID:12045255), (PMID:15746149) RGD PMID:12045255 , PMID:15746149 rostrocaudal neural tube patterning ISO RGD:1346001 1624291 (PMID:20093472) RGD PMID:20093472 Cellular Component apical plasma membrane IDA 5132599 RGD autophagosome membrane IEA UniProtKB-SubCell:SL-0022 1600115 GO_REF:0000044 UniProt GO_REF:0000044 axon IEA UniProtKB-SubCell:SL-0279 1600115 GO_REF:0000044 UniProt GO_REF:0000044 cell body IDA 5132610 RGD cytoplasmic vesicle IEA UniProtKB-KW:KW-0968 1600115 GO_REF:0000043 UniProt GO_REF:0000043 dendritic spine membrane IEA UniProtKB-SubCell:SL-0285 1600115 GO_REF:0000044 UniProt GO_REF:0000044 endoplasmic reticulum membrane ISO RGD:1346001 1624291 (PMID:29127204) RGD PMID:29127204 external side of plasma membrane IBA PANTHER:PTN001000649 , UniProtKB:O75787 13792537 PMID:21873635 GO_Central external side of plasma membrane ISO RGD:1346001 1624291 (PMID:12045255), (PMID:15746149) RGD PMID:12045255 , PMID:15746149 extracellular space IDA 5132599 RGD integral component of membrane IEA UniProtKB-KW:KW-0812 1600115 GO_REF:0000043 UniProt GO_REF:0000043 lysosomal membrane IEA UniProtKB-SubCell:SL-0157 1600115 GO_REF:0000044 UniProt GO_REF:0000044 lysosome ISO RGD:1346001 1624291 (PMID:29127204) RGD PMID:29127204 neuron projection IDA 5132610 RGD postsynaptic membrane IEA UniProtKB-KW:KW-0628 1600115 GO_REF:0000043 UniProt GO_REF:0000043 vacuolar proton-transporting V-type ATPase complex ISO RGD:1346001 1624291 (PMID:29127204) RGD PMID:29127204 Molecular Function molecular_function ND 1598407 20061210: no relevant rat data RGD protein binding ISO RGD:1346001 1624291 UniProtKB:O00526 more ... RGD PMID:12045255 more ... signaling receptor activity IEA InterPro:IPR012493 1600115 GO_REF:0000002 InterPro GO_REF:0000002
Gene-Chemical Interaction Annotations
