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Gene: Atp6ap2 (ATPase H+ transporting accessory protein 2) Rattus norvegicus
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Symbol: Atp6ap2
Name: ATPase H+ transporting accessory protein 2
RGD ID: 1561269
Description: Predicted to have signaling receptor activity. Predicted to be involved in several processes, including angiotensin maturation; lysosomal lumen acidification; and regulation of signal transduction. Localizes to several cellular components, including apical plasma membrane; cell body; and extracellular space. Biomarker of hypertension. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type II and syndromic X-linked intellectual disability Hedera type. Orthologous to human ATP6AP2 (ATPase H+ transporting accessory protein 2); PARTICIPATES IN renin-angiotensin cascade pathway; INTERACTS WITH 2,6-dinitrotoluene; 3-chloropropane-1,2-diol; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ATPase H(+)-transporting lysosomal-interacting protein 2; ATPase, H(+)-transporting, lysosomal-interacting protein 2; ATPase, H+ transporting, lysosomal accessory protein 2; MGC94783; renin receptor; renin/prorenin receptor
Orthologs:
Homo sapiens (human) : ATP6AP2 (ATPase H+ transporting accessory protein 2)  HGNC  Alliance
Mus musculus (house mouse) : Atp6ap2 (ATPase, H+ transporting, lysosomal accessory protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp6ap2 (ATPase H+ transporting accessory protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP6AP2 (ATPase H+ transporting accessory protein 2)
Canis lupus familiaris (dog) : ATP6AP2 (ATPase H+ transporting accessory protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp6ap2 (ATPase H+ transporting accessory protein 2)
Sus scrofa (pig) : ATP6AP2 (ATPase H+ transporting accessory protein 2)
Chlorocebus sabaeus (African green monkey) : ATP6AP2 (ATPase H+ transporting accessory protein 2)
Heterocephalus glaber (naked mole-rat) : Atp6ap2 (ATPase H+ transporting accessory protein 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X11,137,889 - 11,164,854 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX11,136,939 - 11,164,915 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X11,936,459 - 11,963,424 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X22,264,078 - 22,291,988 (-)NCBIRGSC3.4rn4RGSC3.4
CeleraX10,708,369 - 10,735,267 (-)NCBICelera
Cytogenetic MapXq12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Protein Structures
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Atp6ap2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1561269
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.