(S)-nicotine multiple interactions ISO RGD:1352469 6480464 Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of NR1H2 mRNA], Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of NR1H2 protein] CTD PMID:30036686 (S)-nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of NR1H2 mRNA, Nicotine results in decreased expression of NR1H2 protein CTD PMID:30036686 (S)-nicotine decreases expression ISO RGD:1352469 6480464 Nicotine results in decreased expression of NR1H2 mRNA, Nicotine results in decreased expression of NR1H2 protein CTD PMID:30036686 1,2-dimethylhydrazine multiple interactions ISO RGD:62199 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of NR1H2 mRNA CTD PMID:22206623 17beta-estradiol decreases expression ISO RGD:1352469 6480464 Estradiol results in decreased expression of NR1H2 mRNA CTD PMID:15223131 , PMID:16029874 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:62199 6480464 [Tetrachlorodibenzodioxin co-treated with bisphenol A co-treated with 2 more ... CTD PMID:23756648 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:62199 6480464 Tetrachlorodibenzodioxin affects the expression of NR1H2 mRNA CTD PMID:21570461 , PMID:24058054 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:62199 6480464 [Tetrachlorodibenzodioxin co-treated with bisphenol A co-treated with 2 more ... CTD PMID:23756648 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1352469 6480464 Tetrachlorodibenzodioxin results in decreased expression of NR1H2 mRNA CTD PMID:19684285 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of NR1H2 mRNA CTD PMID:21346803 2,6-di-tert-butyl-4-methylphenol multiple interactions ISO RGD:1352469 6480464 Butylated Hydroxytoluene inhibits the reaction [ironII-ascorbic acid complex results in decreased expression of NR1H2 mRNA] CTD PMID:17070507 2-hydroxypropanoic acid decreases expression ISO RGD:1352469 6480464 Lactic Acid results in decreased expression of NR1H2 mRNA CTD PMID:30851411 22-Hydroxycholesterol multiple interactions ISO RGD:1352469 6480464 [Alitretinoin co-treated with 22-hydroxycholesterol] affects the localization of NR1H2 protein CTD PMID:16888799 8-(4-chlorophenylthio)-cAMP multiple interactions ISO RGD:62199 6480464 NR1H2 gene mutant form inhibits the reaction [pitavastatin inhibits the reaction [8-4-chlorophenylthiocyclic-3', 5'-AMP results in increased export of Cholesterol]] CTD PMID:16415093 8-Br-cAMP decreases expression ISO RGD:1352469 6480464 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of NR1H2 mRNA CTD PMID:22079614 9-cis-retinoic acid multiple interactions ISO RGD:1352469 6480464 [Alitretinoin co-treated with 22-hydroxycholesterol] affects the localization of NR1H2 protein CTD PMID:16888799 acrylamide decreases expression ISO RGD:1352469 6480464 Acrylamide results in decreased expression of NR1H2 mRNA CTD PMID:32763439 aflatoxin B1 decreases methylation ISO RGD:1352469 6480464 Aflatoxin B1 results in decreased methylation of NR1H2 intron CTD PMID:30157460 alpha-linolenic acid multiple interactions ISO RGD:62199 6480464 alpha-Linolenic Acid binds to and results in increased activity of NR1H2 protein CTD PMID:16731579 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of NR1H2 mRNA CTD PMID:16483693 arsane increases methylation ISO RGD:1352469 6480464 Arsenic results in increased methylation of NR1H2 promoter CTD PMID:21291286 arsenic atom increases methylation ISO RGD:1352469 6480464 Arsenic results in increased methylation of NR1H2 promoter CTD PMID:21291286 arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of NR1H2 protein CTD PMID:21851829 arsenous acid decreases expression ISO RGD:1352469 6480464 Arsenic Trioxide results in decreased expression of NR1H2 mRNA, Arsenic Trioxide results in decreased expression of NR1H2 protein CTD PMID:27622732 arsenous acid increases expression ISO RGD:62199 6480464 Arsenic Trioxide results in increased expression of NR1H2 mRNA CTD PMID:15073043 arsenous acid multiple interactions EXP 6480464 Cholesterol, Dietary promotes the reaction [Arsenic Trioxide results in decreased expression of NR1H2 protein] CTD PMID:21851829 benzo[a]pyrene decreases methylation ISO RGD:1352469 6480464 Benzoapyrene results in decreased methylation of NR1H2 3' UTR CTD PMID:27901495 benzo[a]pyrene increases methylation ISO RGD:1352469 6480464 Benzoapyrene results in increased methylation of NR1H2 promoter CTD PMID:27901495 beta-naphthoflavone multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of NR1H2 mRNA CTD PMID:18164116 bezafibrate increases expression ISO RGD:1352469 6480464 Bezafibrate results in increased expression of NR1H2 mRNA CTD PMID:19201410 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:62199 6480464 [Tetrachlorodibenzodioxin co-treated with bisphenol A co-treated with 2 more ... CTD PMID:23756648 bisphenol A decreases expression ISO RGD:1352469 6480464 bisphenol A results in decreased expression of NR1H2 mRNA CTD PMID:15223131 bisphenol A affects methylation ISO RGD:62199 6480464 bisphenol A affects the methylation of NR1H2 promoter CTD PMID:27334623 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of NR1H2 gene CTD PMID:28505145 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of NR1H2 mRNA CTD PMID:25181051 bisphenol A multiple interactions ISO RGD:62199 6480464 [Tetrachlorodibenzodioxin co-treated with bisphenol A co-treated with 2 more ... CTD PMID:23756648 bosentan decreases expression ISO RGD:1352469 6480464 Bosentan results in decreased expression of NR1H2 mRNA CTD PMID:29761207 bucladesine multiple interactions ISO RGD:62199 6480464 NR1H2 protein affects the reaction [Bucladesine results in increased phosphorylation of LIPE protein] more ... CTD PMID:23362264 cholesterol increases activity ISO RGD:1352469 6480464 Cholesterol results in increased activity of NR1H2 protein CTD PMID:21543282 cholesterol multiple interactions ISO RGD:62199 6480464 [RXRB protein binds to NR1H2 protein] which affects the metabolism of Cholesterol more ... CTD PMID:14993927 , PMID:16415093 choline multiple interactions ISO RGD:62199 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of NR1H2 gene CTD PMID:20938992 clofibrate decreases expression ISO RGD:62199 6480464 Clofibrate results in decreased expression of NR1H2 mRNA CTD PMID:23811191 dexamethasone affects response to substance ISO RGD:62199 6480464 NR1H2 affects the susceptibility to Dexamethasone CTD PMID:21123945 diarsenic trioxide increases expression ISO RGD:62199 6480464 Arsenic Trioxide results in increased expression of NR1H2 mRNA CTD PMID:15073043 diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of NR1H2 protein CTD PMID:21851829 diarsenic trioxide decreases expression ISO RGD:1352469 6480464 Arsenic Trioxide results in decreased expression of NR1H2 mRNA, Arsenic Trioxide results in decreased expression of NR1H2 protein CTD PMID:27622732 diarsenic trioxide multiple interactions EXP 6480464 Cholesterol, Dietary promotes the reaction [Arsenic Trioxide results in decreased expression of NR1H2 protein] CTD PMID:21851829 etoposide affects localization ISO RGD:1352469 6480464 Etoposide affects the localization of NR1H2 protein CTD PMID:25914138 etoposide affects response to substance ISO RGD:1352469 6480464 NR1H2 protein affects the susceptibility to Etoposide CTD PMID:25914138 etoposide multiple interactions ISO RGD:1352469 6480464 Etoposide promotes the reaction [NR1H2 protein results in increased expression of CETP mRNA], NR1H2 mutant form inhibits the reaction [Etoposide results in increased expression of CETP mRNA] CTD PMID:25914138 ezetimibe decreases expression ISO RGD:1352469 6480464 Ezetimibe results in decreased expression of NR1H2 mRNA CTD PMID:16177187 fenofibrate increases expression ISO RGD:1352469 6480464 Fenofibrate results in increased expression of NR1H2 mRNA CTD PMID:19201410 fenofibrate multiple interactions ISO RGD:62199 6480464 NR1H2 gene mutant form affects the reaction [Fenofibrate results in increased expression of ACACB mRNA] more ... CTD PMID:23063693 finasteride increases expression EXP 6480464 Finasteride results in increased expression of NR1H2 mRNA CTD PMID:24136188 flutamide increases expression EXP 6480464 Flutamide results in increased expression of NR1H2 mRNA CTD PMID:24136188 folic acid multiple interactions ISO RGD:62199 6480464 [1 more ... CTD PMID:20938992 , PMID:22206623 fumonisin B1 affects response to substance ISO RGD:62199 6480464 NR1H2 protein affects the susceptibility to fumonisin B1 CTD PMID:30448865 fumonisin B1 multiple interactions ISO RGD:62199 6480464 [NR1H2 protein affects the susceptibility to fumonisin B1] which affects the expression of ABCG8 mRNA more ... CTD PMID:30448865 gemfibrozil increases expression ISO RGD:1352469 6480464 Gemfibrozil results in increased expression of NR1H2 mRNA CTD PMID:19201410 guggulsterone multiple interactions ISO RGD:62199 6480464 pregna-4 more ... CTD PMID:31421115 GW 3965 multiple interactions ISO RGD:62199 6480464 GW 3965 inhibits the reaction [Palmitic Acid results in decreased expression of NR1H2 mRNA] more ... CTD PMID:27598782 , PMID:31421115 GW 3965 multiple interactions ISO RGD:1352469 6480464 [GW 3965 co-treated with NR1H3 protein] results in decreased expression of NR1H2 mRNA more ... CTD PMID:31932555 GW 501516 increases expression ISO RGD:1352469 6480464 GW 501516 results in increased expression of NR1H2 mRNA CTD PMID:19201410 hexadecanoic acid decreases expression ISO RGD:62199 6480464 Palmitic Acid results in decreased expression of NR1H2 mRNA, Palmitic Acid results in decreased expression of NR1H2 protein CTD PMID:31421115 hexadecanoic acid multiple interactions ISO RGD:62199 6480464 acanthoic acid inhibits the reaction [Palmitic Acid results in decreased expression of NR1H2 mRNA] more ... CTD PMID:31421115 ketoconazole multiple interactions ISO RGD:1352469 6480464 Ketoconazole inhibits the reaction [TO-901317 results in increased activity of NR1H2 protein] CTD PMID:16819505 L-methionine multiple interactions ISO RGD:62199 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of NR1H2 gene CTD PMID:20938992 lansoprazole increases activity ISO RGD:1352469 6480464 Lansoprazole results in increased activity of NR1H2 protein CTD PMID:20060385 lipopolysaccharide decreases expression ISO RGD:62199 6480464 Lipopolysaccharides results in decreased expression of NR1H2 mRNA CTD PMID:16847310 lipopolysaccharide decreases expression EXP 6480464 Lipopolysaccharides results in decreased expression of NR1H2 mRNA, Lipopolysaccharides results in decreased expression of NR1H2 protein CTD PMID:21939782 mono(2-ethylhexyl) phthalate multiple interactions ISO RGD:1352469 6480464 mono-2-ethylhexylphthalate promotes the reaction [NCOA1 protein binds to and results in increased activity of NR1H2 protein] CTD PMID:27551952 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of NR1H2 mRNA CTD PMID:18164116 N-nitrosodiethylamine multiple interactions ISO RGD:62199 6480464 [Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of NR1H2 gene CTD PMID:23968726 nefazodone increases expression EXP 6480464 nefazodone results in increased expression of NR1H2 mRNA CTD PMID:24136188 nicotine multiple interactions ISO RGD:1352469 6480464 Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of NR1H2 mRNA], Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of NR1H2 protein] CTD PMID:30036686 nicotine decreases expression ISO RGD:1352469 6480464 Nicotine results in decreased expression of NR1H2 mRNA, Nicotine results in decreased expression of NR1H2 protein CTD PMID:30036686 nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of NR1H2 mRNA, Nicotine results in decreased expression of NR1H2 protein CTD PMID:30036686 octanoic acid multiple interactions ISO RGD:62199 6480464 octanoic acid binds to and results in increased activity of NR1H2 protein CTD PMID:16731579 paracetamol affects expression ISO RGD:62199 6480464 Acetaminophen affects the expression of NR1H2 mRNA CTD PMID:17562736 paraquat increases expression ISO RGD:62199 6480464 Paraquat results in increased expression of NR1H2 mRNA CTD PMID:27788593 perfluorohexanesulfonic acid decreases expression ISO RGD:62199 6480464 perfluorohexanesulfonic acid results in decreased expression of NR1H2 mRNA CTD PMID:21705711 phorbol 13-acetate 12-myristate increases expression ISO RGD:1352469 6480464 Tetradecanoylphorbol Acetate results in increased expression of NR1H2 mRNA CTD PMID:31011801 pioglitazone increases expression ISO RGD:1352469 6480464 pioglitazone results in increased expression of NR1H2 mRNA CTD PMID:19201410 piperonyl butoxide multiple interactions ISO RGD:62199 6480464 [Piperonyl Butoxide co-treated with Diethylnitrosamine] affects the methylation of NR1H2 gene CTD PMID:23968726 pitavastatin multiple interactions ISO RGD:62199 6480464 NR1H2 gene mutant form inhibits the reaction [pitavastatin inhibits the reaction [8-4-chlorophenylthiocyclic-3' more ... CTD PMID:16415093 pitavastatin(1-) multiple interactions ISO RGD:62199 6480464 NR1H2 gene mutant form inhibits the reaction [pitavastatin inhibits the reaction [8-4-chlorophenylthiocyclic-3' more ... CTD PMID:16415093 rac-lactic acid decreases expression ISO RGD:1352469 6480464 Lactic Acid results in decreased expression of NR1H2 mRNA CTD PMID:30851411 sodium arsenite decreases expression ISO RGD:62199 6480464 sodium arsenite results in decreased expression of NR1H2 mRNA CTD PMID:19822182 streptozocin multiple interactions EXP 6480464 [homocastasterone analog co-treated with Streptozocin] results in increased expression of NR1H2 mRNA, homocastasterone analog inhibits the reaction [Streptozocin results in decreased expression of NR1H2 protein] CTD PMID:28822685 streptozocin decreases expression EXP 6480464 Streptozocin results in decreased expression of NR1H2 protein CTD PMID:28822685 teniposide multiple interactions ISO RGD:1352469 6480464 NR1H2 mutant form inhibits the reaction [Teniposide results in increased expression of CETP mRNA], Teniposide promotes the reaction [NR1H2 protein results in increased expression of CETP mRNA] CTD PMID:25914138 teniposide affects response to substance ISO RGD:1352469 6480464 NR1H2 protein affects the susceptibility to Teniposide CTD PMID:25914138 teniposide affects localization ISO RGD:1352469 6480464 Teniposide affects the localization of NR1H2 protein CTD PMID:25914138 tetrachloromethane multiple interactions ISO RGD:62199 6480464 acanthoic acid inhibits the reaction [Carbon Tetrachloride results in decreased expression of NR1H2 protein] CTD PMID:24802811 tetrachloromethane decreases expression ISO RGD:62199 6480464 Carbon Tetrachloride results in decreased expression of NR1H2 protein CTD PMID:24802811 titanium dioxide increases expression ISO RGD:62199 6480464 titanium dioxide results in increased expression of NR1H2 mRNA CTD PMID:29264374 trichostatin A affects expression ISO RGD:1352469 6480464 trichostatin A affects the expression of NR1H2 mRNA CTD PMID:28542535 triphenyl phosphate multiple interactions ISO RGD:1352469 6480464 [Dust results in increased abundance of triphenyl phosphate] inhibits the reaction [TO-901317 results in increased activity of NR1H2 protein], triphenyl phosphate inhibits the reaction [TO-901317 results in increased activity of NR1H2 protein] CTD PMID:31724879 triptonide increases expression ISO RGD:62199 6480464 triptonide results in increased expression of NR1H2 mRNA CTD PMID:33045310 uranium atom decreases expression EXP 6480464 Uranium results in decreased expression of NR1H2 mRNA CTD PMID:17118558 valproic acid decreases expression ISO RGD:1352469 6480464 Valproic Acid results in decreased expression of NR1H2 mRNA CTD PMID:29154799 valproic acid increases methylation ISO RGD:1352469 6480464 Valproic Acid results in increased methylation of NR1H2 gene CTD PMID:29154799 vecuronium bromide multiple interactions ISO RGD:1352469 6480464 Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of NR1H2 mRNA], Vecuronium Bromide inhibits the reaction [Nicotine results in decreased expression of NR1H2 protein] CTD PMID:30036686 vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of NR1H2 mRNA CTD PMID:19015723
