Gene: Rbbp8 (RB binding protein 8, endonuclease) Rattus norvegicus
Symbol: Rbbp8
Name: RB binding protein 8, endonuclease
Description: ENCODES a protein that exhibits damaged DNA binding (ortholog); identical protein binding (ortholog); RNA polymerase II repressing transcription factor binding (ortholog); INVOLVED IN response to estradiol; blastocyst hatching (ortholog); DNA double-strand break processing involved in repair via single-strand annealing (ortholog); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; homologous recombination pathway of double-strand break repair; Notch signaling pathway; ASSOCIATED WITH Microcephaly with Mental Retardation and Digital Anomalies (ortholog); pancreatic cancer (ortholog); pancreatic carcinoma (ortholog); FOUND IN intracellular membrane-bounded organelle (ortholog); nucleoplasm (ortholog); transcriptional repressor complex (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; bisphenol A; endosulfan
Type: protein-coding
Also known as: ctBP-interacting protein; CtIP; DNA endonuclease RBBP8; LOC291787; RBBP-8; retinoblastoma binding protein 8; retinoblastoma-binding protein 8; retinoblastoma-interacting protein and myosin-like; RGD1308872; RIM; SAE2; similar to Retinoblastoma-binding protein 8 (RBBP-8) (CtBP interacting protein) (CtIP) (Retinoblastoma-interacting protein and myosin-like) (RIM); sporulation in the absence of SPO11 protein 2 homolog
Homo sapiens (human) : RBBP8 (RB binding protein 8, endonuclease)  HGNC  Alliance
Mus musculus (house mouse) : Rbbp8 (retinoblastoma binding protein 8, endonuclease)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rbbp8 (RB binding protein 8, endonuclease)
Pan paniscus (bonobo/pygmy chimpanzee) : RBBP8 (RB binding protein 8, endonuclease)
Canis lupus familiaris (dog) : RBBP8 (RB binding protein 8, endonuclease)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rbbp8 (RB binding protein 8, endonuclease)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0183,134,630 - 3,227,702 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0183,173,428 - 3,239,961 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4183,266,565 - 3,333,153 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1183,269,885 - 3,333,117 (+)NCBI
Celera182,790,129 - 2,855,180 (+)NCBICelera
Cytogenetic Map18p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Rbbp8
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308872
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2018-10-09
Status: ACTIVE