Gene: Rbbp8 (RB binding protein 8, endonuclease) Rattus norvegicus
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Symbol: Rbbp8
Name: RB binding protein 8, endonuclease
Description: ENCODES a protein that exhibits damaged DNA binding (ortholog); identical protein binding (ortholog); RNA polymerase II repressing transcription factor binding (ortholog); INVOLVED IN response to estradiol; blastocyst hatching (ortholog); DNA double-strand break processing involved in repair via single-strand annealing (ortholog); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; homologous recombination pathway of double-strand break repair; Notch signaling pathway; ASSOCIATED WITH Microcephaly with Mental Retardation and Digital Anomalies (ortholog); pancreatic cancer (ortholog); pancreatic carcinoma (ortholog); FOUND IN intracellular membrane-bounded organelle (ortholog); nucleoplasm (ortholog); transcriptional repressor complex (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; bisphenol A; endosulfan
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ctBP-interacting protein; CtIP; DNA endonuclease RBBP8; LOC291787; RBBP-8; retinoblastoma binding protein 8; retinoblastoma-binding protein 8; retinoblastoma-interacting protein and myosin-like; RGD1308872; RIM; SAE2; similar to Retinoblastoma-binding protein 8 (RBBP-8) (CtBP interacting protein) (CtIP) (Retinoblastoma-interacting protein and myosin-like) (RIM); sporulation in the absence of SPO11 protein 2 homolog
Orthologs:
Homo sapiens (human) : RBBP8 (RB binding protein 8, endonuclease)  HGNC  Alliance
Mus musculus (house mouse) : Rbbp8 (retinoblastoma binding protein 8, endonuclease)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rbbp8 (RB binding protein 8, endonuclease)
Pan paniscus (bonobo/pygmy chimpanzee) : RBBP8 (RB binding protein 8, endonuclease)
Canis lupus familiaris (dog) : RBBP8 (RB binding protein 8, endonuclease)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rbbp8 (RB binding protein 8, endonuclease)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0183,134,630 - 3,227,702 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0183,173,428 - 3,239,961 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4183,266,565 - 3,333,153 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1183,269,885 - 3,333,117 (+)NCBI
Celera182,790,129 - 2,855,180 (+)NCBICelera
Cytogenetic Map18p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Rbbp8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308872
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2018-10-09
Status: ACTIVE