(+)-catechin increases expression ISO RGD:737367 6480464 Catechin results in increased expression of NOTCH1 mRNA CTD PMID:15465739 (+)-dexrazoxane multiple interactions ISO RGD:10998 6480464 Dexrazoxane inhibits the reaction [Doxorubicin results in increased expression of NOTCH1 protein] CTD PMID:30517846 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane multiple interactions ISO RGD:737367 6480464 MAPK1 protein promotes the reaction [o more ... CTD PMID:18791200 1,2-dimethylhydrazine increases expression EXP 6480464 1, 2-Dimethylhydrazine results in increased expression of NOTCH1 mRNA CTD PMID:32387197 1,2-dimethylhydrazine decreases expression ISO RGD:10998 6480464 1, 2-Dimethylhydrazine results in decreased expression of NOTCH1 mRNA CTD PMID:22206623 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Trimetazidine inhibits the reaction [Paclitaxel results in decreased expression of NOTCH1 mRNA]], Trimetazidine inhibits the reaction [Paclitaxel results in decreased expression of NOTCH1 mRNA] CTD PMID:35662665 17alpha-ethynylestradiol multiple interactions ISO RGD:10998 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NOTCH1 mRNA CTD PMID:17942748 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of NOTCH1 mRNA CTD PMID:17557909 17beta-estradiol multiple interactions ISO RGD:737367 6480464 [Estradiol co-treated with TGFB1 protein] results in decreased expression of NOTCH1 mRNA, Estradiol promotes the reaction [NOTCH1 protein binds to CCND1 promoter] CTD PMID:19838210 , PMID:30165855 17beta-estradiol increases expression ISO RGD:737367 6480464 Estradiol results in increased expression of NOTCH1 mRNA CTD PMID:31614463 17beta-estradiol multiple interactions ISO RGD:10998 6480464 [Estradiol co-treated with Progesterone] results in decreased expression of NOTCH1 mRNA, Estradiol inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of NOTCH1 protein] CTD PMID:19693291 , PMID:35537655 17beta-estradiol affects expression ISO RGD:10998 6480464 Estradiol affects the expression of NOTCH1 mRNA CTD PMID:15598610 2,2',4,4',5,5'-hexachlorobiphenyl increases expression EXP 6480464 2 more ... CTD PMID:21908764 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:10998 6480464 Tetrachlorodibenzodioxin affects the expression of NOTCH1 mRNA CTD PMID:18343893 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of NOTCH1 mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of NOTCH1 mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:737367 6480464 [Tetrachlorodibenzodioxin co-treated with 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide] results in decreased expression of NOTCH1 mRNA CTD PMID:29704546 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:10998 6480464 Tetrachlorodibenzodioxin results in increased expression of NOTCH1 mRNA CTD PMID:10886394 more ... 2,3,7,8-tetrachlorodibenzodioxine affects activity ISO RGD:10998 6480464 Tetrachlorodibenzodioxin affects the activity of NOTCH1 protein CTD PMID:25585350 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:10998 6480464 Tetrachlorodibenzodioxin results in decreased expression of NOTCH1 mRNA CTD PMID:17586704 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:10998 6480464 [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of NOTCH1 mRNA more ... CTD PMID:15667827 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:737367 6480464 Tetrachlorodibenzodioxin results in increased expression of NOTCH1 mRNA CTD PMID:19684285 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:737367 6480464 Tetrachlorodibenzodioxin results in decreased expression of NOTCH1 mRNA CTD PMID:19684285 2,3,7,8-Tetrachlorodibenzofuran increases expression ISO RGD:10998 6480464 2 more ... CTD PMID:20702594 2,3,7,8-Tetrachlorodibenzofuran affects expression ISO RGD:10998 6480464 2 more ... CTD PMID:18343893 2-acetamidofluorene increases expression ISO RGD:10998 6480464 2-Acetylaminofluorene results in increased expression of NOTCH1 mRNA CTD PMID:21607683 2-tert-butylhydroquinone decreases expression EXP 6480464 2-tert-butylhydroquinone results in decreased expression of NOTCH1 protein CTD PMID:29663635 3,3',4,4',5-pentachlorobiphenyl increases expression ISO RGD:10998 6480464 3 more ... CTD PMID:18042819 more ... 3,3',5,5'-tetrabromobisphenol A increases expression EXP 6480464 tetrabromobisphenol A results in increased expression of NOTCH1 mRNA CTD PMID:32041402 3,3',5,5'-tetrabromobisphenol A increases expression ISO RGD:10998 6480464 tetrabromobisphenol A results in increased expression of NOTCH1 mRNA CTD PMID:35230478 3,4-methylenedioxymethamphetamine increases expression EXP 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of NOTCH1 mRNA CTD PMID:30071829 4,4'-sulfonyldiphenol multiple interactions ISO RGD:737367 6480464 [bis(4-hydroxyphenyl)sulfone co-treated with Fulvestrant] results in decreased methylation of NOTCH1 gene CTD PMID:31601247 4-hydroxynon-2-enal decreases expression ISO RGD:10998 6480464 4-hydroxy-2-nonenal results in decreased expression of NOTCH1 mRNA CTD PMID:19191707 5-aza-2'-deoxycytidine multiple interactions ISO RGD:737367 6480464 [Decitabine co-treated with trichostatin A] results in decreased expression of NOTCH1 mRNA CTD PMID:17185465 5-fluorouracil multiple interactions ISO RGD:737367 6480464 [Fluorouracil co-treated with Chloroquine] results in increased expression of NOTCH1 protein CTD PMID:29917191 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of NOTCH1 mRNA CTD PMID:24780913 , PMID:25825206 7,12-dimethyltetraphene increases expression ISO RGD:10998 6480464 9 more ... CTD PMID:32553695 aconitine increases expression EXP 6480464 Aconitine results in increased expression of NOTCH1 protein, Aconitine results in increased expression of NOTCH1 protein modified form CTD PMID:32234357 aconitine increases expression ISO RGD:737367 6480464 Aconitine results in increased expression of NOTCH1 protein modified form CTD PMID:32234357 aconitine multiple interactions ISO RGD:737367 6480464 Aconitine promotes the reaction [NOTCH1 protein modified form binds to HCN4 promoter] more ... CTD PMID:32234357 aconitine multiple interactions EXP 6480464 Aconitine affects the reaction [NOTCH1 protein modified form binds to HCN4 promoter], crenigacestat inhibits the reaction [Aconitine results in increased expression of NOTCH1 protein modified form] CTD PMID:32234357 aconitine affects expression ISO RGD:737367 6480464 Aconitine affects the expression of NOTCH1 protein CTD PMID:32234357 acrylamide decreases expression ISO RGD:10998 6480464 Acrylamide results in decreased expression of NOTCH1 mRNA CTD PMID:30807115 aflatoxin B1 increases expression ISO RGD:10998 6480464 Aflatoxin B1 results in increased expression of NOTCH1 mRNA CTD PMID:19770486 aflatoxin B1 multiple interactions ISO RGD:737367 6480464 [Zearalenone co-treated with Aflatoxin B1] results in increased expression of NOTCH1 mRNA CTD PMID:28965971 all-trans-retinoic acid multiple interactions ISO RGD:737367 6480464 [Tretinoin co-treated with Phenylbutyrates co-treated with 1-hydroxy-2-oxo-3, 3-bis(2-aminoethyl)-1-triazene] results in increased expression of NOTCH1 protein CTD PMID:23284745 all-trans-retinoic acid increases expression ISO RGD:737367 6480464 Tretinoin results in increased expression of NOTCH1 mRNA, Tretinoin results in increased expression of NOTCH1 protein CTD PMID:28130038 , PMID:33167477 all-trans-retinoic acid decreases expression ISO RGD:737367 6480464 Tretinoin results in decreased expression of NOTCH1 mRNA CTD PMID:21934132 , PMID:22906706 alpha-D-galactose multiple interactions ISO RGD:10998 6480464 [Galactose co-treated with Aluminum Chloride] results in increased expression of NOTCH1 protein more ... CTD PMID:35537655 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of NOTCH1 mRNA CTD PMID:16483693 arecoline increases expression ISO RGD:10998 151347668 arecoline cotreated with dimethyl sulfoxide increases expression of Notch1 protein in tongue RGD aristolochic acid A increases expression ISO RGD:737367 6480464 aristolochic acid I results in increased expression of NOTCH1 mRNA CTD PMID:33212167 arsane multiple interactions ISO RGD:10998 6480464 arginyl-2 more ... CTD PMID:32647881 arsane increases expression ISO RGD:10998 6480464 [Arsenic results in increased expression of NOTCH1 protein] which results in increased expression of DLL4 protein, Arsenic results in increased expression of NOTCH1 mRNA CTD PMID:32647881 arsenic atom multiple interactions ISO RGD:10998 6480464 arginyl-2 more ... CTD PMID:32647881 arsenic atom increases expression ISO RGD:10998 6480464 [Arsenic results in increased expression of NOTCH1 protein] which results in increased expression of DLL4 protein, Arsenic results in increased expression of NOTCH1 mRNA CTD PMID:32647881 arsenite(3-) multiple interactions ISO RGD:737367 6480464 arsenite inhibits the reaction [G3BP1 protein binds to NOTCH1 mRNA], RTKI cpd inhibits the reaction [arsenite results in decreased expression of NOTCH1 protein modified form] CTD PMID:18633435 , PMID:32406909 arsenite(3-) increases expression ISO RGD:737367 6480464 arsenite results in increased expression of NOTCH1 protein CTD PMID:22011395 arsenite(3-) decreases expression ISO RGD:737367 6480464 arsenite results in decreased expression of NOTCH1 protein modified form CTD PMID:18633435 arsenous acid multiple interactions ISO RGD:737367 6480464 4-(4-(N-benzoylamino)anilino)-6-methoxy-7-(3-(1-morpholino)propoxy)quinazoline inhibits the reaction [Arsenic Trioxide results in decreased expression of NOTCH1 protein] more ... CTD PMID:23542114 more ... arsenous acid increases expression ISO RGD:737367 6480464 Arsenic Trioxide results in increased expression of NOTCH1 mRNA, Arsenic Trioxide results in increased expression of NOTCH1 protein CTD PMID:29738779 arsenous acid decreases expression ISO RGD:737367 6480464 Arsenic Trioxide results in decreased expression of NOTCH1 more ... CTD PMID:22949821 more ... arsenous acid decreases response to substance ISO RGD:737367 6480464 NOTCH1 protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:22949821 arsenous acid decreases activity ISO RGD:737367 6480464 Arsenic Trioxide results in decreased activity of NOTCH1 protein CTD PMID:23542114 aspartame multiple interactions ISO RGD:10998 6480464 [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of NOTCH1 mRNA CTD PMID:23783067 aspartame affects localization ISO RGD:737367 6480464 Aspartame affects the localization of NOTCH1 protein modified form CTD PMID:33992720 aspartame multiple interactions ISO RGD:737367 6480464 TAS1R1 protein affects the reaction [Aspartame affects the localization of NOTCH1 protein modified form] CTD PMID:33992720 azoxystrobin decreases expression ISO RGD:737367 6480464 azoxystrobin results in decreased expression of NOTCH1 mRNA CTD PMID:33512557 baicalein increases activity ISO RGD:737367 6480464 baicalein results in increased activity of NOTCH1 protein CTD PMID:19160421 baicalein increases expression ISO RGD:737367 6480464 baicalein results in increased expression of NOTCH1 mRNA CTD PMID:19160421 baicalin increases activity ISO RGD:737367 6480464 baicalin results in increased activity of NOTCH1 protein CTD PMID:19160421 baicalin increases expression ISO RGD:737367 6480464 baicalin results in increased expression of NOTCH1 mRNA CTD PMID:19160421 benzene increases expression ISO RGD:737367 6480464 Benzene results in increased expression of NOTCH1 mRNA CTD PMID:24993241 benzo[a]pyrene increases expression ISO RGD:10998 6480464 Benzo(a)pyrene results in increased expression of NOTCH1 mRNA CTD PMID:19770486 more ... benzo[a]pyrene multiple interactions EXP 6480464 Benzo(a)pyrene promotes the reaction [Dibutyl Phthalate results in increased expression of NOTCH1 mRNA] more ... CTD PMID:35378083 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of NOTCH1 mRNA, Benzo(a)pyrene results in increased expression of NOTCH1 protein CTD PMID:35378083 benzo[a]pyrene multiple interactions ISO RGD:10998 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of NOTCH1 mRNA CTD PMID:27858113 benzo[b]fluoranthene multiple interactions ISO RGD:10998 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of NOTCH1 mRNA CTD PMID:27858113 beta-naphthoflavone increases expression ISO RGD:10998 6480464 beta-Naphthoflavone results in increased expression of NOTCH1 mRNA CTD PMID:23994337 bis(2-chloroethyl) sulfide decreases expression EXP 6480464 Mustard Gas results in decreased expression of NOTCH1 mRNA CTD PMID:28402575 bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of NOTCH1 protein CTD PMID:29663635 bisphenol A decreases expression ISO RGD:10998 6480464 bisphenol A results in decreased expression of NOTCH1 mRNA CTD PMID:21932408 , PMID:35278557 bisphenol A increases expression ISO RGD:10998 6480464 bisphenol A results in increased expression of NOTCH1 mRNA CTD PMID:32156529 bisphenol A multiple interactions ISO RGD:737367 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of NOTCH1 gene CTD PMID:31601247 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of NOTCH1 mRNA, bisphenol A results in increased expression of NOTCH1 protein CTD PMID:29323181 , PMID:29438945 bisphenol A affects methylation ISO RGD:10998 6480464 bisphenol A affects the methylation of NOTCH1 promoter CTD PMID:27334623 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of NOTCH1 gene CTD PMID:28505145 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of NOTCH1 mRNA CTD PMID:25181051 bisphenol A decreases expression ISO RGD:737367 6480464 bisphenol A results in decreased expression of NOTCH1 mRNA CTD PMID:26363213 bisphenol F decreases expression ISO RGD:10998 6480464 bisphenol F results in decreased expression of NOTCH1 mRNA CTD PMID:35278557 Botulinum toxin type A decreases response to substance ISO RGD:10998 6480464 NOTCH1 results in decreased susceptibility to Botulinum Toxins, Type A CTD PMID:23884415 cadmium dichloride increases methylation EXP 6480464 Cadmium Chloride results in increased methylation of NOTCH1 promoter CTD PMID:22457795 cadmium dichloride multiple interactions ISO RGD:737367 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cadmium Chloride results in increased cleavage of NOTCH1 protein] more ... CTD PMID:25118938 caffeine multiple interactions ISO RGD:737367 6480464 NOTCH1 protein mutant form inhibits the reaction [Caffeine promotes the reaction [[Doxorubicin co-treated with Nocodazole co-treated with Hydroxyurea] results in increased cleavage of CASP3 protein]] CTD PMID:31597699 calciol increases expression ISO RGD:10998 6480464 Cholecalciferol results in increased expression of NOTCH1 mRNA CTD PMID:17170073 captan decreases expression ISO RGD:10998 6480464 Captan results in decreased expression of NOTCH1 mRNA CTD PMID:31558096 carbon nanotube decreases expression ISO RGD:10998 6480464 Nanotubes more ... CTD PMID:25554681 chloroquine multiple interactions ISO RGD:737367 6480464 [Fluorouracil co-treated with Chloroquine] results in increased expression of NOTCH1 protein CTD PMID:29917191 chlorpyrifos decreases expression EXP 6480464 Chlorpyrifos results in decreased expression of NOTCH1 mRNA CTD PMID:18668222 chlorpyrifos increases expression ISO RGD:10998 6480464 Chlorpyrifos results in increased expression of NOTCH1 mRNA, Chlorpyrifos results in increased expression of NOTCH1 protein modified form CTD PMID:32715474 chromium(6+) multiple interactions ISO RGD:10998 6480464 MAP2K7 protein promotes the reaction [chromium hexavalent ion results in increased expression of NOTCH1 mRNA] CTD PMID:19654923 chromium(6+) increases expression ISO RGD:10998 6480464 chromium hexavalent ion results in increased expression of NOTCH1 mRNA CTD PMID:19654923 chrysene decreases expression ISO RGD:10998 6480464 chrysene results in decreased expression of NOTCH1 mRNA CTD PMID:26377693 chrysene multiple interactions ISO RGD:10998 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of NOTCH1 mRNA CTD PMID:27858113 cis-caffeic acid multiple interactions EXP 6480464 caffeic acid inhibits the reaction [Valproic Acid results in increased expression of NOTCH1 mRNA] CTD PMID:29968957 cisplatin decreases expression ISO RGD:737367 6480464 Cisplatin results in decreased expression of NOTCH1 mRNA CTD PMID:27594783 clobetasol decreases expression ISO RGD:10998 6480464 Clobetasol results in decreased expression of NOTCH1 mRNA CTD PMID:27462272 cobalt dichloride increases expression ISO RGD:737367 6480464 cobaltous chloride results in increased expression of NOTCH1 mRNA CTD PMID:22941251 cobalt dichloride decreases expression EXP 6480464 cobaltous chloride results in decreased expression of NOTCH1 mRNA CTD PMID:24386269 crocidolite asbestos decreases expression ISO RGD:10998 6480464 Asbestos, Crocidolite results in decreased expression of NOTCH1 mRNA CTD PMID:23917077 Cuprizon multiple interactions EXP 6480464 Cuprizone results in increased cleavage of and results in increased activity of NOTCH1 protein CTD PMID:31168611 curcumin decreases expression ISO RGD:737367 6480464 Curcumin results in decreased expression of NOTCH1 mRNA, Curcumin results in decreased expression of NOTCH1 protein CTD PMID:17927689 , PMID:18640131 curcumin multiple interactions ISO RGD:737367 6480464 [Curcumin co-treated with Isoflavones] results in decreased expression of NOTCH1 protein CTD PMID:18640131 Cyclopamine multiple interactions ISO RGD:737367 6480464 [2-(2-(3 more ... CTD PMID:21498710 Cyclopamine decreases cleavage ISO RGD:737367 6480464 cyclopamine results in decreased cleavage of NOTCH1 protein CTD PMID:21498710 DAPT multiple interactions ISO RGD:737367 6480464 N-(N-(3 more ... CTD PMID:22039516 more ... DAPT decreases expression ISO RGD:737367 6480464 N-(N-(3, 5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester results in decreased expression of NOTCH1 protein modified form CTD PMID:18633435 DAPT multiple interactions ISO RGD:10998 6480464 N-(N-(3 more ... CTD PMID:22115781 , PMID:24223152 DDT increases activity ISO RGD:737367 6480464 DDT results in increased activity of NOTCH1 protein CTD PMID:18791200 DDT multiple interactions ISO RGD:737367 6480464 MAP2K6 protein promotes the reaction [DDT results in increased activity of NOTCH1 protein] CTD PMID:18791200 dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of NOTCH1 mRNA CTD PMID:14618091 dexamethasone multiple interactions EXP 6480464 Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of NOTCH1 mRNA] CTD PMID:18449946 diallyl trisulfide decreases expression ISO RGD:737367 6480464 diallyl trisulfide results in decreased expression of NOTCH1 mRNA, diallyl trisulfide results in decreased expression of NOTCH1 protein CTD PMID:23430952 diallyl trisulfide multiple interactions ISO RGD:737367 6480464 NOTCH1 mutant form promotes the reaction [diallyl trisulfide results in decreased activity of MMP2 protein] more ... CTD PMID:23430952 diarsenic trioxide decreases response to substance ISO RGD:737367 6480464 NOTCH1 protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:22949821 diarsenic trioxide decreases expression ISO RGD:737367 6480464 Arsenic Trioxide results in decreased expression of NOTCH1 more ... CTD PMID:22949821 more ... diarsenic trioxide decreases activity ISO RGD:737367 6480464 Arsenic Trioxide results in decreased activity of NOTCH1 protein CTD PMID:23542114 diarsenic trioxide multiple interactions ISO RGD:737367 6480464 4-(4-(N-benzoylamino)anilino)-6-methoxy-7-(3-(1-morpholino)propoxy)quinazoline inhibits the reaction [Arsenic Trioxide results in decreased expression of NOTCH1 protein] more ... CTD PMID:23542114 more ... diarsenic trioxide increases expression ISO RGD:737367 6480464 Arsenic Trioxide results in increased expression of NOTCH1 mRNA, Arsenic Trioxide results in increased expression of NOTCH1 protein CTD PMID:29738779 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of NOTCH1 mRNA, Dibutyl Phthalate results in increased expression of NOTCH1 protein CTD PMID:29438945 , PMID:35378083 dibutyl phthalate multiple interactions EXP 6480464 Benzo(a)pyrene promotes the reaction [Dibutyl Phthalate results in increased expression of NOTCH1 mRNA] more ... CTD PMID:35378083 dicrotophos increases expression ISO RGD:737367 6480464 dicrotophos results in increased expression of NOTCH1 mRNA CTD PMID:28302478 dieldrin affects expression EXP 6480464 Dieldrin affects the expression of NOTCH1 mRNA CTD PMID:22546817 diethyl maleate increases expression ISO RGD:737367 6480464 diethyl maleate results in increased expression of NOTCH1 mRNA CTD PMID:33545341 diethylstilbestrol decreases expression ISO RGD:10998 6480464 Diethylstilbestrol results in decreased expression of NOTCH1 mRNA CTD PMID:21041162 dimethylarsinic acid affects expression EXP 6480464 Cacodylic Acid affects the expression of NOTCH1 mRNA CTD PMID:17720352 dioxygen multiple interactions ISO RGD:10998 6480464 N-(N-(3 more ... CTD PMID:24223152 dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of NOTCH1 mRNA, Oxygen deficiency results in increased expression of NOTCH1 protein CTD PMID:24223152 dioxygen affects localization EXP 6480464 Oxygen deficiency affects the localization of NOTCH1 protein modified form CTD PMID:24223152 dioxygen affects localization ISO RGD:10998 6480464 Oxygen deficiency affects the localization of NOTCH1 protein modified form CTD PMID:24223152 dioxygen increases expression ISO RGD:10998 6480464 Oxygen deficiency results in increased expression of NOTCH1 mRNA, Oxygen deficiency results in increased expression of NOTCH1 protein CTD PMID:24223152 doxorubicin multiple interactions EXP 6480464 paeonol affects the reaction [Doxorubicin results in decreased expression of NOTCH1 mRNA] CTD PMID:31307187 doxorubicin multiple interactions ISO RGD:737367 6480464 Doxorubicin inhibits the reaction [Nocodazole promotes the reaction [Hydroxyurea results in decreased expression of NOTCH1 protein]], NOTCH1 protein mutant form inhibits the reaction [Caffeine promotes the reaction [[Doxorubicin co-treated with Nocodazole co-treated with Hydroxyurea] results in increased cleavage of CASP3 protein]] CTD PMID:31597699 doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of NOTCH1 mRNA CTD PMID:31307187 doxorubicin increases expression ISO RGD:10998 6480464 Doxorubicin results in increased expression of NOTCH1 protein CTD PMID:30517846 doxorubicin increases cleavage EXP 6480464 Doxorubicin results in increased cleavage of NOTCH1 protein CTD PMID:31307187 doxorubicin multiple interactions ISO RGD:10998 6480464 Dexrazoxane inhibits the reaction [Doxorubicin results in increased expression of NOTCH1 protein] CTD PMID:30517846 emodin decreases expression EXP 6480464 Emodin results in decreased expression of NOTCH1 protein CTD PMID:27989784 emodin multiple interactions EXP 6480464 2'-deoxythymidylyl-(3'-5')-2'-deoxyadenosine promotes the reaction [Emodin inhibits the reaction [TGFB1 protein results in increased expression of NOTCH1 protein]] more ... CTD PMID:27989784 emodin decreases response to substance EXP 6480464 NOTCH1 protein results in decreased susceptibility to Emodin CTD PMID:27989784 enzalutamide affects response to substance ISO RGD:737367 6480464 NOTCH1 protein affects the susceptibility to enzalutamide CTD PMID:30940724 enzalutamide multiple interactions ISO RGD:737367 6480464 [NOTCH1 protein affects the susceptibility to enzalutamide] which affects the cleavage of PARP1 protein CTD PMID:30940724 enzalutamide affects expression ISO RGD:737367 6480464 enzalutamide affects the expression of NOTCH1 mRNA CTD PMID:30940724 epoxiconazole increases expression ISO RGD:10998 6480464 epoxiconazole results in increased expression of NOTCH1 mRNA CTD PMID:35436446 ethanol decreases activity EXP 6480464 Ethanol results in decreased activity of NOTCH1 protein CTD PMID:16770775 ethanol increases expression ISO RGD:10998 6480464 Ethanol results in increased expression of NOTCH1 mRNA CTD PMID:30319688 ethyl methanesulfonate increases expression ISO RGD:737367 6480464 Ethyl Methanesulfonate results in increased expression of NOTCH1 mRNA CTD PMID:23649840 eugenol decreases expression ISO RGD:737367 6480464 Eugenol results in decreased expression of NOTCH1 mRNA, Eugenol results in decreased expression of NOTCH1 protein CTD PMID:31926151 eugenol decreases expression ISO RGD:10998 6480464 Eugenol results in decreased expression of NOTCH1 protein CTD PMID:31926151 fenamidone increases expression ISO RGD:10998 6480464 fenamidone results in increased expression of NOTCH1 mRNA CTD PMID:27029645 fenofibrate multiple interactions ISO RGD:10998 6480464 Fenofibrate inhibits the reaction [triptolide results in increased expression of NOTCH1 mRNA] CTD PMID:31241159 fluoxetine increases expression EXP 6480464 Fluoxetine results in increased expression of NOTCH1 mRNA, Fluoxetine results in increased expression of NOTCH1 protein CTD PMID:19801843 folic acid increases expression EXP 6480464 Folic Acid results in increased expression of NOTCH1 mRNA, Folic Acid results in increased expression of NOTCH1 protein CTD PMID:20838574 folpet decreases expression ISO RGD:10998 6480464 folpet results in decreased expression of NOTCH1 mRNA CTD PMID:31558096 formaldehyde increases expression ISO RGD:737367 6480464 Formaldehyde results in increased expression of NOTCH1 mRNA CTD PMID:23649840 fulvestrant multiple interactions ISO RGD:737367 6480464 [bis(4-hydroxyphenyl)sulfone co-treated with Fulvestrant] results in decreased methylation of NOTCH1 gene, [bisphenol A co-treated with Fulvestrant] results in increased methylation of NOTCH1 gene CTD PMID:31601247 furan decreases expression EXP 6480464 furan results in decreased expression of NOTCH1 mRNA CTD PMID:25539665 galactose multiple interactions ISO RGD:10998 6480464 [Galactose co-treated with Aluminum Chloride] results in increased expression of NOTCH1 protein more ... CTD PMID:35537655 gemcitabine multiple interactions ISO RGD:737367 6480464 sulforaphane inhibits the reaction [Gemcitabine results in increased expression of NOTCH1 protein] CTD PMID:20940707 gemcitabine increases expression ISO RGD:737367 6480464 Gemcitabine results in increased expression of NOTCH1 protein CTD PMID:20940707 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of NOTCH1 mRNA CTD PMID:22061828 , PMID:33387578 glyphosate increases methylation EXP 6480464 glyphosate results in increased methylation of NOTCH1 gene CTD PMID:31011160 glyphosate increases activity ISO RGD:737367 6480464 glyphosate results in increased activity of NOTCH1 protein CTD PMID:35485992 glyphosate increases expression ISO RGD:737367 6480464 glyphosate results in increased expression of NOTCH1 mRNA CTD PMID:31295307 hexadecanoic acid decreases expression EXP 6480464 Palmitic Acid results in decreased expression of NOTCH1 protein, Palmitic Acid results in decreased expression of NOTCH1 protein modified form CTD PMID:34897970 hexadecanoic acid multiple interactions EXP 6480464 MIR141 mRNA promotes the reaction [Palmitic Acid results in decreased expression of NOTCH1 protein modified form], MIR141 mRNA promotes the reaction [Palmitic Acid results in decreased expression of NOTCH1 protein] CTD PMID:34897970 hydrogen peroxide increases cleavage ISO RGD:737367 6480464 Hydrogen Peroxide results in increased cleavage of NOTCH1 protein CTD PMID:25108166 hydrogen peroxide multiple interactions ISO RGD:737367 6480464 HIF1A protein affects the reaction [Hydrogen Peroxide results in increased cleavage of NOTCH1 protein] more ... CTD PMID:25108166 hydroxyurea decreases expression ISO RGD:737367 6480464 Hydroxyurea results in decreased expression of NOTCH1 protein CTD PMID:31597699 hydroxyurea multiple interactions ISO RGD:737367 6480464 Doxorubicin inhibits the reaction [Nocodazole promotes the reaction [Hydroxyurea results in decreased expression of NOTCH1 protein]] more ... CTD PMID:31597699 isoflavones multiple interactions ISO RGD:737367 6480464 [Curcumin co-treated with Isoflavones] results in decreased expression of NOTCH1 protein CTD PMID:18640131 isoflavones decreases expression ISO RGD:737367 6480464 Isoflavones results in decreased expression of NOTCH1 protein CTD PMID:18640131 isoprenaline multiple interactions EXP 6480464 [Isoproterenol co-treated with POSTN protein] results in decreased expression of NOTCH1 mRNA CTD PMID:30303030 isoprenaline decreases expression EXP 6480464 Isoproterenol results in decreased expression of NOTCH1 mRNA CTD PMID:30303030 kaempferol 3-O-beta-D-glucoside multiple interactions ISO RGD:10998 6480464 astragalin inhibits the reaction [[Galactose co-treated with Aluminum Chloride] results in increased expression of NOTCH1 protein] CTD PMID:35537655 Licochalcone B increases expression ISO RGD:737367 6480464 licochalcone B results in increased expression of NOTCH1 mRNA CTD PMID:33647349 lipopolysaccharide increases expression ISO RGD:10998 6480464 Lipopolysaccharides results in increased expression of NOTCH1 protein CTD PMID:18449946 lipopolysaccharide increases expression ISO RGD:737367 6480464 Lipopolysaccharides results in increased expression of NOTCH1 protein CTD PMID:35385713 lipopolysaccharide multiple interactions ISO RGD:737367 6480464 ITCH protein inhibits the reaction [Lipopolysaccharides results in increased expression of NOTCH1 protein] more ... CTD PMID:35385713 lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of NOTCH1 mRNA, Lipopolysaccharides results in increased expression of NOTCH1 protein CTD PMID:18449946 lipopolysaccharide multiple interactions EXP 6480464 Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of NOTCH1 mRNA] CTD PMID:18449946 lipopolysaccharide multiple interactions ISO RGD:10998 6480464 NOTCH1 protein affects the reaction [Lipopolysaccharides results in increased expression of CSF1 mRNA] more ... CTD PMID:18449946 lithium chloride decreases expression ISO RGD:737367 6480464 Lithium Chloride results in decreased expression of NOTCH1 mRNA CTD PMID:23527032 LY294002 multiple interactions ISO RGD:10998 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Zinc affects the localization of NOTCH1 protein], 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Zinc results in decreased activity of NOTCH1 protein] CTD PMID:17513037 LY294002 multiple interactions ISO RGD:737367 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cadmium Chloride results in increased cleavage of NOTCH1 protein] CTD PMID:25118938 mebendazole decreases expression ISO RGD:737367 6480464 Mebendazole results in decreased expression of NOTCH1 protein CTD PMID:32277947 methyl methanesulfonate increases expression ISO RGD:737367 6480464 Methyl Methanesulfonate results in increased expression of NOTCH1 mRNA CTD PMID:23649840 methylmercury chloride affects expression EXP 6480464 methylmercuric chloride affects the expression of NOTCH1 mRNA CTD PMID:20864626 methylmercury chloride multiple interactions ISO RGD:10998 6480464 methylmercuric chloride affects the reaction [ITPR3 protein affects the expression of NOTCH1 mRNA] CTD PMID:33166615 miconazole increases expression ISO RGD:10998 6480464 Miconazole results in increased expression of NOTCH1 mRNA CTD PMID:27462272 Mitotane increases activity ISO RGD:737367 6480464 Mitotane results in increased activity of NOTCH1 protein CTD PMID:18791200 monosodium L-glutamate multiple interactions ISO RGD:10998 6480464 [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of NOTCH1 mRNA CTD PMID:23783067 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:737367 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arsenic Trioxide results in decreased expression of NOTCH1 protein], benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [triptonide results in increased degradation of NOTCH1 protein] CTD PMID:24801890 more ... N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression ISO RGD:737367 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of NOTCH1 mRNA CTD PMID:24497960 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:737367 6480464 KLF4 protein affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of NOTCH1 protein] more ... CTD PMID:29611404 N-methyl-4-phenylpyridinium affects expression ISO RGD:737367 6480464 1-Methyl-4-phenylpyridinium affects the expression of NOTCH1 protein CTD PMID:29611404 N-nitrosodiethylamine multiple interactions ISO RGD:10998 6480464 RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of NOTCH1 mRNA] CTD PMID:17854601 N-nitrosodiethylamine increases expression ISO RGD:10998 6480464 Diethylnitrosamine results in increased expression of NOTCH1 mRNA CTD PMID:17854601 , PMID:21607683 nickel dichloride increases expression ISO RGD:737367 6480464 nickel chloride results in increased expression of NOTCH1 protein CTD PMID:26962057 nickel dichloride affects expression EXP 6480464 nickel chloride affects the expression of NOTCH1 mRNA CTD PMID:22546817 niclosamide decreases activity ISO RGD:737367 6480464 Niclosamide results in decreased activity of NOTCH1 protein CTD PMID:19160421 niclosamide multiple interactions EXP 6480464 Niclosamide inhibits the reaction [Thioacetamide results in increased expression of NOTCH1 mRNA], Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of NOTCH1 mRNA]] CTD PMID:32961231 nicotinic acid increases expression EXP 6480464 Niacin results in increased expression of NOTCH1 protein CTD PMID:19223914 nocodazole decreases expression ISO RGD:737367 6480464 Nocodazole results in decreased expression of NOTCH1 protein CTD PMID:31597699 nocodazole multiple interactions ISO RGD:737367 6480464 BI 2536 inhibits the reaction [Nocodazole results in decreased expression of NOTCH1 protein] more ... CTD PMID:31597699 ochratoxin A increases acetylation ISO RGD:737367 6480464 ochratoxin A results in increased acetylation of NOTCH1 promoter CTD PMID:29098329 omacetaxine mepesuccinate multiple interactions ISO RGD:737367 6480464 Arsenic Trioxide inhibits the reaction [Homoharringtonine results in increased expression of NOTCH1 protein] CTD PMID:31307525 omacetaxine mepesuccinate increases expression ISO RGD:737367 6480464 Homoharringtonine results in increased expression of NOTCH1 protein CTD PMID:31307525 oxaliplatin affects response to substance ISO RGD:737367 6480464 NOTCH1 protein affects the susceptibility to oxaliplatin CTD PMID:19147571 oxaliplatin multiple interactions ISO RGD:737367 6480464 Sulfonamides inhibits the reaction [oxaliplatin results in increased expression of NOTCH1 protein modified form] CTD PMID:19147571 oxaliplatin increases expression ISO RGD:737367 6480464 oxaliplatin results in increased expression of NOTCH1 protein modified form CTD PMID:19147571 oxidopamine multiple interactions ISO RGD:737367 6480464 MIR107 mRNA affects the reaction [Oxidopamine affects the expression of NOTCH1 protein], PDCD10 protein affects the reaction [MIR107 mRNA affects the reaction [Oxidopamine affects the expression of NOTCH1 protein]] CTD PMID:31778666 oxidopamine affects expression ISO RGD:737367 6480464 Oxidopamine affects the expression of NOTCH1 protein CTD PMID:31778666 oxidopamine multiple interactions EXP 6480464 MIR107 mRNA affects the reaction [Oxidopamine affects the expression of NOTCH1 protein], PDCD10 protein affects the reaction [MIR107 mRNA affects the reaction [Oxidopamine affects the expression of NOTCH1 protein]] CTD PMID:31778666 oxidopamine affects expression EXP 6480464 Oxidopamine affects the expression of NOTCH1 protein CTD PMID:31778666 ozone multiple interactions ISO RGD:10998 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of NOTCH1 mRNA CTD PMID:34911549 paclitaxel multiple interactions ISO RGD:737367 6480464 [NOTCH1 protein results in decreased susceptibility to Paclitaxel] which results in decreased expression of CASP9 protein modified form more ... CTD PMID:34048126 paclitaxel multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Trimetazidine inhibits the reaction [Paclitaxel results in decreased expression of NOTCH1 mRNA]], Trimetazidine inhibits the reaction [Paclitaxel results in decreased expression of NOTCH1 mRNA] CTD PMID:35662665 paclitaxel decreases expression EXP 6480464 Paclitaxel results in decreased expression of NOTCH1 mRNA CTD PMID:35662665 paclitaxel decreases response to substance ISO RGD:737367 6480464 NOTCH1 protein results in decreased susceptibility to Paclitaxel CTD PMID:34048126 Paeonol increases expression EXP 6480464 paeonol results in increased expression of NOTCH1 mRNA CTD PMID:31307187 Paeonol increases cleavage EXP 6480464 paeonol results in increased cleavage of NOTCH1 protein CTD PMID:31307187 Paeonol multiple interactions EXP 6480464 paeonol affects the reaction [Doxorubicin results in decreased expression of NOTCH1 mRNA] CTD PMID:31307187 paracetamol increases expression ISO RGD:737367 6480464 Acetaminophen results in increased expression of NOTCH1 mRNA CTD PMID:22230336 , PMID:29067470 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of NOTCH1 mRNA CTD PMID:33387578 paraquat affects expression ISO RGD:737367 6480464 Paraquat affects the expression of NOTCH1 mRNA CTD PMID:24053911 pentachlorophenol increases expression ISO RGD:10998 6480464 Pentachlorophenol results in increased expression of NOTCH1 mRNA CTD PMID:23892564 phenethyl isothiocyanate multiple interactions ISO RGD:737367 6480464 N-(N-(3 more ... CTD PMID:22039516 phenethyl isothiocyanate increases expression ISO RGD:737367 6480464 phenethyl isothiocyanate results in increased expression of NOTCH1 mRNA CTD PMID:22039516 picropodophyllotoxin multiple interactions ISO RGD:737367 6480464 picropodophyllin inhibits the reaction [Cadmium Chloride results in increased cleavage of NOTCH1 protein] CTD PMID:25118938 pirinixic acid increases expression ISO RGD:10998 6480464 pirinixic acid results in increased expression of NOTCH1 mRNA CTD PMID:18301758 , PMID:23811191 pluronic P-123 multiple interactions EXP 6480464 Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of NOTCH1 mRNA]] CTD PMID:32961231 Poloxamer multiple interactions EXP 6480464 Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of NOTCH1 mRNA]] CTD PMID:32961231 poly(ethylene) decreases expression ISO RGD:737367 6480464 Polyethylene results in decreased expression of NOTCH1 mRNA CTD PMID:23203475 potassium chromate increases expression ISO RGD:737367 6480464 potassium chromate(VI) results in increased expression of NOTCH1 mRNA CTD PMID:22714537 progesterone multiple interactions ISO RGD:10998 6480464 [Estradiol co-treated with Progesterone] results in decreased expression of NOTCH1 mRNA CTD PMID:19693291 propiconazole decreases expression ISO RGD:10998 6480464 propiconazole results in decreased expression of NOTCH1 mRNA CTD PMID:21278054 propranolol decreases expression ISO RGD:737367 6480464 Propranolol results in decreased expression of NOTCH1 protein CTD PMID:30130526 prostaglandin F2alpha decreases cleavage EXP 6480464 Dinoprost results in decreased cleavage of NOTCH1 protein CTD PMID:21209419 prostaglandin F2alpha decreases expression EXP 6480464 Dinoprost results in decreased expression of NOTCH1 mRNA CTD PMID:21209419 quercetin multiple interactions ISO RGD:737367 6480464 [2-(2-(3 more ... CTD PMID:20032413 more ... resveratrol multiple interactions ISO RGD:737367 6480464 MRK 003 inhibits the reaction [Resveratrol results in increased activity of NOTCH1] more ... CTD PMID:21743969 , PMID:23594881 resveratrol affects expression ISO RGD:737367 6480464 resveratrol affects the expression of NOTCH1 mRNA, resveratrol affects the expression of NOTCH1 protein CTD PMID:25896424 resveratrol increases expression ISO RGD:737367 6480464 resveratrol results in increased expression of NOTCH1 mRNA, resveratrol results in increased expression of NOTCH1 protein CTD PMID:23594881 resveratrol decreases expression ISO RGD:737367 6480464 resveratrol results in decreased expression of NOTCH1 mRNA, resveratrol results in decreased expression of NOTCH1 protein CTD PMID:17868649 , PMID:25061499 resveratrol increases activity ISO RGD:737367 6480464 resveratrol results in increased activity of NOTCH1 CTD PMID:21743969 retinyl acetate increases expression ISO RGD:10998 6480464 retinol acetate results in increased expression of NOTCH1 mRNA CTD PMID:16772331 rotenone decreases expression ISO RGD:737367 6480464 Rotenone results in decreased expression of NOTCH1 mRNA CTD PMID:33512557 Salidroside decreases expression ISO RGD:10998 6480464 rhodioloside results in decreased expression of NOTCH1 mRNA CTD PMID:24929042 SB 203580 multiple interactions ISO RGD:737367 6480464 SB 203580 inhibits the reaction [o, p'-DDT results in increased activity of NOTCH1 protein] CTD PMID:18791200 simvastatin increases cleavage EXP 6480464 Simvastatin results in increased cleavage of NOTCH1 protein CTD PMID:19109527 simvastatin increases expression EXP 6480464 Simvastatin results in increased expression of NOTCH1 mRNA CTD PMID:19109527 sirolimus affects expression EXP 6480464 Sirolimus affects the expression of NOTCH1 protein CTD PMID:26676567 sodium arsenite affects expression ISO RGD:737367 6480464 sodium arsenite affects the expression of NOTCH1 mRNA CTD PMID:20056578 sodium arsenite decreases expression ISO RGD:10998 6480464 sodium arsenite results in decreased expression of NOTCH1 mRNA CTD PMID:30130555 sodium arsenite increases expression ISO RGD:737367 6480464 sodium arsenite results in increased expression of NOTCH1 mRNA CTD PMID:17879257 sodium arsenite multiple interactions ISO RGD:737367 6480464 sodium arsenite inhibits the reaction [BMP6 protein results in increased activity of NOTCH1 protein], sodium arsenite inhibits the reaction [U 0126 results in increased activity of NOTCH1 protein] CTD PMID:23566955 sodium dichromate increases expression ISO RGD:737367 6480464 sodium bichromate results in increased expression of NOTCH1 protein CTD PMID:28624442 sodium dichromate multiple interactions ISO RGD:737367 6480464 FBP1 protein inhibits the reaction [sodium bichromate results in increased expression of NOTCH1 protein] CTD PMID:28624442 sulforaphane multiple interactions ISO RGD:737367 6480464 sulforaphane inhibits the reaction [Gemcitabine results in increased expression of NOTCH1 protein] CTD PMID:20940707 sunitinib increases expression ISO RGD:737367 6480464 Sunitinib results in increased expression of NOTCH1 mRNA CTD PMID:31533062 T-2 toxin increases expression EXP 6480464 T-2 Toxin results in increased expression of NOTCH1 mRNA CTD PMID:26141394 tamoxifen decreases expression EXP 6480464 Tamoxifen results in decreased expression of NOTCH1 protein CTD PMID:17343880 tamoxifen multiple interactions EXP 6480464 [Tamoxifen results in increased expression of MIR34A mRNA] which results in decreased expression of NOTCH1 protein CTD PMID:17343880 temozolomide increases expression ISO RGD:737367 6480464 Temozolomide results in increased expression of NOTCH1 mRNA CTD PMID:31758290 testosterone decreases expression ISO RGD:10998 6480464 Testosterone results in decreased expression of NOTCH1 mRNA CTD PMID:19693291 testosterone decreases expression ISO RGD:737367 6480464 Testosterone results in decreased expression of NOTCH1 mRNA CTD PMID:33359661 tetraphene multiple interactions ISO RGD:10998 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of NOTCH1 mRNA CTD PMID:27858113 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of NOTCH1 mRNA CTD PMID:32961231 , PMID:34492290 thioacetamide multiple interactions EXP 6480464 Niclosamide inhibits the reaction [Thioacetamide results in increased expression of NOTCH1 mRNA], Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of NOTCH1 mRNA]] CTD PMID:32961231 titanium dioxide affects expression ISO RGD:10998 6480464 titanium dioxide affects the expression of NOTCH1 mRNA CTD PMID:17656681 titanium dioxide decreases methylation ISO RGD:737367 6480464 titanium dioxide results in decreased methylation of NOTCH1 gene, titanium dioxide results in decreased methylation of NOTCH1 promoter CTD PMID:34973136 toluene multiple interactions ISO RGD:737367 6480464 [Toluene co-treated with Xylenes] results in decreased expression of NOTCH1 mRNA, [Toluene co-treated with Xylenes] results in increased methylation of NOTCH1 gene CTD PMID:33438815 trans-caffeic acid multiple interactions EXP 6480464 caffeic acid inhibits the reaction [Valproic Acid results in increased expression of NOTCH1 mRNA] CTD PMID:29968957 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of NOTCH1 mRNA CTD PMID:33387578 trichostatin A multiple interactions ISO RGD:737367 6480464 [decitabine co-treated with trichostatin A] results in decreased expression of NOTCH1 mRNA CTD PMID:17185465 triclosan decreases expression ISO RGD:10998 6480464 Triclosan results in decreased expression of NOTCH1 mRNA, Triclosan results in decreased expression of NOTCH1 protein CTD PMID:36243240 triphenylstannane decreases expression ISO RGD:737367 6480464 triphenyltin results in decreased expression of NOTCH1 mRNA CTD PMID:12788061 Triptolide increases expression ISO RGD:10998 6480464 triptolide results in increased expression of NOTCH1 mRNA CTD PMID:31241159 , PMID:32835833 Triptolide decreases expression ISO RGD:737367 6480464 triptolide results in decreased expression of NOTCH1 mRNA more ... CTD PMID:30394310 Triptolide multiple interactions ISO RGD:10998 6480464 Fenofibrate inhibits the reaction [triptolide results in increased expression of NOTCH1 mRNA] more ... CTD PMID:30394310 , PMID:31241159 Triptolide multiple interactions ISO RGD:737367 6480464 NOTCH1 protein modified form inhibits the reaction [triptolide results in decreased expression of TXN protein] CTD PMID:30394310 triptonide multiple interactions ISO RGD:737367 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [triptonide results in increased degradation of NOTCH1 protein], triptonide results in increased ubiquitination of and results in increased degradation of NOTCH1 protein CTD PMID:31866380 tungsten decreases expression ISO RGD:10998 6480464 Tungsten results in decreased expression of NOTCH1 mRNA CTD PMID:30912803 tunicamycin increases cleavage ISO RGD:10998 6480464 Tunicamycin results in increased cleavage of NOTCH1 protein CTD PMID:22115781 tunicamycin multiple interactions ISO RGD:10998 6480464 N-(N-(3, 5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [Tunicamycin results in increased cleavage of NOTCH1 protein] CTD PMID:22115781 tyrphostin AG 1478 multiple interactions ISO RGD:737367 6480464 RTKI cpd inhibits the reaction [arsenite results in decreased expression of NOTCH1 protein modified form], RTKI cpd inhibits the reaction [Cadmium Chloride results in increased cleavage of NOTCH1 protein] CTD PMID:18633435 , PMID:25118938 tyrphostin AG 1478 increases expression ISO RGD:737367 6480464 RTKI cpd results in increased expression of NOTCH1 protein modified form CTD PMID:18633435 uranium atom decreases expression EXP 6480464 Uranium results in decreased expression of NOTCH1 mRNA CTD PMID:27639536 urethane increases expression ISO RGD:737367 6480464 Urethane results in increased expression of NOTCH1 mRNA CTD PMID:28818685 valproic acid increases methylation ISO RGD:737367 6480464 Valproic Acid results in increased methylation of NOTCH1 gene CTD PMID:29154799 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of NOTCH1 mRNA CTD PMID:29968957 valproic acid multiple interactions EXP 6480464 caffeic acid inhibits the reaction [Valproic Acid results in increased expression of NOTCH1 mRNA] CTD PMID:29968957 valproic acid decreases expression ISO RGD:737367 6480464 Valproic Acid results in decreased expression of NOTCH1 mRNA CTD PMID:23179753 , PMID:23527032 vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of NOTCH1 mRNA CTD PMID:19015723 wortmannin multiple interactions ISO RGD:10998 6480464 wortmannin inhibits the reaction [Zinc affects the localization of NOTCH1 protein], wortmannin inhibits the reaction [Zinc results in decreased activity of NOTCH1 protein] CTD PMID:17513037 zalcitabine increases mutagenesis ISO RGD:10998 6480464 Zalcitabine results in increased mutagenesis of NOTCH1 gene CTD PMID:18798262 zearalenone multiple interactions ISO RGD:737367 6480464 [Zearalenone co-treated with Aflatoxin B1] results in increased expression of NOTCH1 mRNA CTD PMID:28965971 zinc atom multiple interactions ISO RGD:10998 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Zinc affects the localization of NOTCH1 protein] more ... CTD PMID:17513037 zinc atom affects localization ISO RGD:10998 6480464 Zinc affects the localization of NOTCH1 protein CTD PMID:17513037 zinc atom decreases activity ISO RGD:10998 6480464 Zinc results in decreased activity of NOTCH1 protein CTD PMID:17513037 zinc(0) multiple interactions ISO RGD:10998 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Zinc affects the localization of NOTCH1 protein] more ... CTD PMID:17513037 zinc(0) decreases activity ISO RGD:10998 6480464 Zinc results in decreased activity of NOTCH1 protein CTD PMID:17513037 zinc(0) affects localization ISO RGD:10998 6480464 Zinc affects the localization of NOTCH1 protein CTD PMID:17513037
