NOTCH1 (notch receptor 1) - Rat Genome Database

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Gene: NOTCH1 (notch receptor 1) Canis lupus familiaris
Analyze
Symbol: NOTCH1
Name: notch receptor 1
RGD ID: 12105645
Description: ENCODES a protein that exhibits calcium ion binding (inferred); chromatin binding (inferred); chromatin DNA binding (inferred); INVOLVED IN animal organ regeneration (ortholog); apoptotic process (ortholog); apoptotic process involved in embryonic digit morphogenesis (ortholog); PARTICIPATES IN altered Notch signaling pathway involving the main players; Notch signaling pathway; Notch signaling pathway; ASSOCIATED WITH Adams-Oliver syndrome (ortholog); Adams-Oliver Syndrome 2 (ortholog); Adams-Oliver Syndrome 5 (ortholog); FOUND IN acrosomal vesicle (ortholog); glutamatergic synapse (ortholog); postsynaptic density membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: N1ICD; neurogenic locus notch homolog protein 1; notch 1; Notch homolog 1, translocation-associated
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1948,975,972 - 49,018,985 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl948,974,757 - 49,017,277 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha948,226,361 - 48,269,900 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0949,852,205 - 49,895,734 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl949,851,628 - 49,894,186 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1948,633,237 - 48,676,758 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0948,926,759 - 48,970,231 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0948,974,423 - 49,017,941 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Adams-Oliver syndrome  (ISO)
Adams-Oliver Syndrome 2  (ISO)
Adams-Oliver Syndrome 5  (ISO)
adenoid cystic carcinoma  (ISO)
adenoiditis  (ISO)
adult T-cell leukemia/lymphoma  (ISO)
amyotrophic lateral sclerosis  (ISO)
aortic valve disease  (ISO)
aortic valve disease 1  (ISO)
ARTERIAL DISSECTION  (ISO)
atherosclerosis  (ISO)
autism spectrum disorder  (ISO)
autosomal dominant intellectual developmental disorder 8  (ISO)
autosomal dominant nocturnal frontal lobe epilepsy 5  (ISO)
autosomal recessive limb-girdle muscular dystrophy type 2A  (ISO)
bicuspid aortic valve disease  (ISO)
Breast Neoplasms  (ISO)
Calcification of Aortic Valve  (ISO)
calcinosis  (ISO)
Cardiomegaly  (ISO)
Cardiovascular Abnormalities  (ISO)
Carotid Artery Injuries  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
cholangiocarcinoma  (ISO)
cholesteatoma of middle ear  (ISO)
Colonic Neoplasms  (ISO)
Congenital Abnormalities  (ISO)
congenital heart disease  (ISO)
connective tissue disease  (ISO)
Craniofacial Abnormalities  (ISO)
developmental and epileptic encephalopathy 14  (ISO)
Diabetic Cardiomyopathies  (ISO)
Diabetic Foot  (ISO)
diabetic retinopathy  (ISO)
Ehlers-Danlos syndrome classic type 1  (ISO)
Ehlers-Danlos syndrome hypermobility type  (ISO)
endometrial cancer  (ISO)
epilepsy  (ISO)
esophageal atresia  (ISO)
esophagus squamous cell carcinoma  (ISO)
Experimental Autoimmune Uveitis  (ISO)
Experimental Liver Neoplasms  (ISO)
Focal Nodular Hyperplasia  (ISO)
genetic disease  (ISO)
glioblastoma  (ISO)
heart valve disease  (ISO)
hemangiopericytoma  (ISO)
hypoplastic left heart syndrome  (ISO)
Joubert syndrome 1  (ISO)
keratoacanthoma  (ISO)
Kleefstra syndrome 1  (ISO)
Leigh disease  (ISO)
lung adenocarcinoma  (ISO)
lung large cell carcinoma  (ISO)
lung non-small cell carcinoma  (ISO)
lung small cell carcinoma  (ISO)
lymphoma  (ISO)
malignant astrocytoma  (ISO)
Marfan syndrome  (ISO)
Marfanoid Hypermobility Syndrome  (ISO)
microphthalmia  (ISO)
myeloproliferative neoplasm  (ISO)
Myocardial Ischemia  (ISO)
Neoplastic Cell Transformation  (ISO)
nervous system disease  (ISO)
oral squamous cell carcinoma  (ISO)
pancreatic cancer  (ISO)
pancreatic ductal carcinoma  (ISO)
Peritoneal Diseases  (ISO)
primary coenzyme Q10 deficiency 7  (ISO)
prion disease  (ISO)
Pulmonary Arterial Hypertension  (ISO)
pulmonary fibrosis  (ISO)
pulmonary hypertension  (ISO)
Rafiq syndrome  (ISO)
retinopathy of prematurity  (ISO)
scoliosis  (ISO)
SHONE COMPLEX  (ISO)
Skin Neoplasms  (ISO)
Splenomegaly  (ISO)
squamous cell carcinoma  (ISO)
Subacute Necrotizing Encephalopathy of Leigh, Infantile  (ISO)
Surgical Wound  (ISO)
syndromic microphthalmia 5  (ISO)
T-cell acute lymphoblastic leukemia  (ISO)
tetralogy of Fallot  (ISO)
thoracic aortic aneurysm  (ISO)
transient cerebral ischemia  (ISO)
tuberous sclerosis 1  (ISO)
Uterine Cervical Neoplasms  (ISO)
Vascular Malformations  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
angiogenesis  (IEA)
animal organ regeneration  (ISO)
aortic valve morphogenesis  (IEA)
apoptotic process  (IEA,ISO)
apoptotic process involved in embryonic digit morphogenesis  (IEA,ISO)
arterial endothelial cell differentiation  (IEA)
astrocyte differentiation  (ISO)
atrioventricular node development  (IEA)
atrioventricular valve morphogenesis  (IEA)
auditory receptor cell fate commitment  (IEA,ISO)
axonogenesis  (IEA,ISO)
branching morphogenesis of an epithelial tube  (IEA,ISO)
calcium-ion regulated exocytosis  (IEA,ISO)
cardiac atrium morphogenesis  (IEA)
cardiac chamber formation  (IEA)
cardiac epithelial to mesenchymal transition  (IEA)
cardiac left ventricle morphogenesis  (IEA)
cardiac muscle cell myoblast differentiation  (IEA)
cardiac muscle cell proliferation  (IEA)
cardiac muscle tissue morphogenesis  (IEA)
cardiac right atrium morphogenesis  (IEA)
cardiac right ventricle formation  (IEA,ISO)
cardiac septum morphogenesis  (IEA)
cardiac vascular smooth muscle cell development  (IEA)
cardiac ventricle morphogenesis  (IEA)
cell differentiation  (IEA,ISO)
cell differentiation in spinal cord  (ISO)
cell migration involved in endocardial cushion formation  (IEA)
cell population proliferation  (IEA,ISO)
cellular response to follicle-stimulating hormone stimulus  (IEA)
cellular response to hypoxia  (IEA)
cellular response to tumor cell  (IEA)
cellular response to vascular endothelial growth factor stimulus  (IEA)
chemical synaptic transmission, postsynaptic  (IEA)
collecting duct development  (IEA)
compartment pattern specification  (IEA,ISO)
coronary artery morphogenesis  (IEA)
coronary sinus valve morphogenesis  (IEA)
coronary vein morphogenesis  (IEA)
determination of left/right symmetry  (IEA,ISO)
distal tubule development  (IEA)
embryonic hindlimb morphogenesis  (IEA,ISO)
embryonic limb morphogenesis  (IEA,ISO)
endocardial cell differentiation  (IEA)
endocardial cushion development  (IEA,ISO)
endocardial cushion morphogenesis  (IEA)
endocardium development  (IEA)
endocardium morphogenesis  (IEA)
endoderm development  (IEA,ISO)
epidermal cell fate specification  (IEA,ISO)
epidermis development  (IEA,ISO)
epithelial cell fate commitment  (IEA,ISO)
epithelial cell proliferation  (IEA,ISO)
epithelial to mesenchymal transition  (IEA,ISO)
epithelial to mesenchymal transition involved in endocardial cushion formation  (IEA)
forebrain development  (IEA,ISO)
foregut morphogenesis  (IEA,ISO)
gene expression  (IEA)
glial cell differentiation  (IEA,ISO)
glomerular mesangial cell development  (IEA)
growth involved in heart morphogenesis  (IEA)
hair follicle morphogenesis  (IEA,ISO)
heart development  (IEA)
heart looping  (IEA)
heart trabecula morphogenesis  (IEA)
homeostasis of number of cells within a tissue  (IEA)
humoral immune response  (IEA,ISO)
in utero embryonic development  (IEA,ISO)
inflammatory response to antigenic stimulus  (IEA,ISO)
inhibition of neuroepithelial cell differentiation  (IEA,ISO)
interleukin-17-mediated signaling pathway  (IEA)
keratinocyte differentiation  (IEA,ISO)
left/right axis specification  (IEA)
liver development  (IEA,ISO)
lung development  (IEA,ISO)
luteolysis  (ISO)
mesenchymal cell development  (IEA)
mitral valve formation  (IEA)
negative regulation of anoikis  (IEA)
negative regulation of biomineral tissue development  (IEA)
negative regulation of BMP signaling pathway  (IEA)
negative regulation of calcium ion-dependent exocytosis  (IEA,ISO)
negative regulation of canonical Wnt signaling pathway  (IEA,ISO)
negative regulation of cardiac muscle cell apoptotic process  (ISO)
negative regulation of cardiac muscle hypertrophy  (IEA)
negative regulation of catalytic activity  (ISO)
negative regulation of cell adhesion molecule production  (IEA)
negative regulation of cell migration involved in sprouting angiogenesis  (IEA)
negative regulation of cell population proliferation  (IEA)
negative regulation of cell proliferation involved in heart valve morphogenesis  (IEA)
negative regulation of cell-cell adhesion mediated by cadherin  (IEA)
negative regulation of cell-substrate adhesion  (IEA)
negative regulation of cold-induced thermogenesis  (IEA)
negative regulation of collagen biosynthetic process  (ISO)
negative regulation of DNA-templated transcription  (IEA)
negative regulation of endothelial cell chemotaxis  (IEA)
negative regulation of epithelial cell proliferation  (IEA,ISO)
negative regulation of extracellular matrix constituent secretion  (IEA)
negative regulation of gene expression  (IEA)
negative regulation of glial cell proliferation  (IEA)
negative regulation of inner ear auditory receptor cell differentiation  (IEA,ISO)
negative regulation of myoblast differentiation  (IEA)
negative regulation of myotube differentiation  (IEA)
negative regulation of neurogenesis  (IEA)
negative regulation of neuron differentiation  (IEA,ISO)
negative regulation of oligodendrocyte differentiation  (IEA)
negative regulation of ossification  (IEA)
negative regulation of osteoblast differentiation  (IEA)
negative regulation of photoreceptor cell differentiation  (IEA,ISO)
negative regulation of pro-B cell differentiation  (IEA)
negative regulation of programmed cell death  (IEA,ISO)
negative regulation of stem cell differentiation  (IEA)
negative regulation of transcription by RNA polymerase II  (IEA)
neural tube development  (IEA,ISO)
neuroendocrine cell differentiation  (IEA,ISO)
neuron differentiation  (IEA,ISO)
neuron fate commitment  (IEA,ISO)
neuronal stem cell population maintenance  (IEA)
Notch signaling pathway  (IEA,ISO)
Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation  (IEA,ISO)
oligodendrocyte differentiation  (IEA,ISO)
outflow tract morphogenesis  (IEA)
pericardium morphogenesis  (IEA)
positive regulation of aorta morphogenesis  (IEA,ISO)
positive regulation of apoptotic process  (IEA,ISO)
positive regulation of apoptotic process involved in morphogenesis  (IEA)
positive regulation of astrocyte differentiation  (IEA)
positive regulation of BMP signaling pathway  (IEA)
positive regulation of cardiac epithelial to mesenchymal transition  (ISO)
positive regulation of cardiac muscle cell proliferation  (IEA)
positive regulation of cell migration  (IEA)
positive regulation of cell population proliferation  (IEA)
positive regulation of DNA-templated transcription  (IEA,ISO)
positive regulation of endothelial cell differentiation  (ISO)
positive regulation of epithelial cell proliferation  (IEA,ISO)
positive regulation of epithelial to mesenchymal transition  (IEA)
positive regulation of ERK1 and ERK2 cascade  (IEA)
positive regulation of gene expression  (IEA)
positive regulation of glial cell differentiation  (ISO)
positive regulation of keratinocyte differentiation  (IEA,ISO)
positive regulation of neuroblast proliferation  (ISO)
positive regulation of Notch signaling pathway  (IEA,ISO)
positive regulation of Ras protein signal transduction  (IEA)
positive regulation of receptor signaling pathway via JAK-STAT  (IEA)
positive regulation of smooth muscle cell differentiation  (IEA)
positive regulation of transcription by RNA polymerase II  (IEA,ISO)
positive regulation of transcription of Notch receptor target  (IEA,ISO)
positive regulation of viral genome replication  (IEA)
positive regulation of viral transcription  (ISO)
prostate gland epithelium morphogenesis  (IEA,ISO)
protein catabolic process  (IEA)
protein import into nucleus  (IEA)
pulmonary valve morphogenesis  (IEA)
regulation of cardioblast proliferation  (ISO)
regulation of cell adhesion involved in heart morphogenesis  (IEA)
regulation of cell migration  (IEA)
regulation of cell population proliferation  (ISO)
regulation of developmental process  (IEA)
regulation of DNA-templated transcription  (IEA)
regulation of epithelial cell proliferation  (IEA,ISO)
regulation of epithelial cell proliferation involved in prostate gland development  (IEA,ISO)
regulation of extracellular matrix assembly  (IEA)
regulation of gene expression  (IEA,ISO)
regulation of inner ear auditory receptor cell differentiation  (IEA,ISO)
regulation of neurogenesis  (IEA,ISO)
regulation of Notch signaling pathway  (IEA,ISO)
regulation of postsynaptic neurotransmitter receptor activity  (ISO)
regulation of somitogenesis  (IEA,ISO)
regulation of stem cell proliferation  (IEA,ISO)
regulation of transcription by RNA polymerase II  (IEA,ISO)
response to lipopolysaccharide  (ISO)
response to muramyl dipeptide  (IEA)
retinal cone cell differentiation  (IEA,ISO)
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development  (IEA,ISO)
skeletal muscle cell differentiation  (IEA,ISO)
somatic stem cell division  (IEA,ISO)
spermatogenesis  (ISO)
sprouting angiogenesis  (IEA,ISO)
T-helper 17 type immune response  (IEA)
tissue regeneration  (ISO)
transcription by RNA polymerase II  (IEA,ISO)
tube formation  (IEA)
vasculogenesis involved in coronary vascular morphogenesis  (IEA)
venous blood vessel morphogenesis  (IEA,ISO)
venous endothelial cell differentiation  (IEA)
ventricular septum morphogenesis  (IEA)
ventricular trabecula myocardium morphogenesis  (IEA)

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NOTCH1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1948,975,972 - 49,018,985 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl948,974,757 - 49,017,277 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha948,226,361 - 48,269,900 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0949,852,205 - 49,895,734 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl949,851,628 - 49,894,186 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1948,633,237 - 48,676,758 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0948,926,759 - 48,970,231 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0948,974,423 - 49,017,941 (+)NCBIUU_Cfam_GSD_1.0
NOTCH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389136,494,433 - 136,546,048 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9136,494,433 - 136,546,048 (-)EnsemblGRCh38hg38GRCh38
GRCh379139,388,885 - 139,440,500 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369138,508,717 - 138,560,059 (-)NCBINCBI36Build 36hg18NCBI36
Build 349136,664,733 - 136,716,075NCBI
Celera9109,903,340 - 109,955,631 (-)NCBICelera
Cytogenetic Map9q34.3NCBI
HuRef9108,848,155 - 108,928,442 (-)NCBIHuRef
CHM1_19139,537,630 - 139,588,846 (-)NCBICHM1_1
T2T-CHM13v2.09148,723,532 - 148,777,907 (-)NCBIT2T-CHM13v2.0
Notch1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39226,347,914 - 26,393,834 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl226,347,915 - 26,406,675 (-)EnsemblGRCm39 Ensembl
GRCm38226,457,902 - 26,503,822 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl226,457,903 - 26,516,663 (-)EnsemblGRCm38mm10GRCm38
MGSCv37226,313,422 - 26,359,342 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36226,280,033 - 26,325,646 (-)NCBIMGSCv36mm8
Celera226,175,736 - 26,221,759 (-)NCBICelera
Cytogenetic Map2A3NCBI
cM Map218.91NCBI
Notch1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8329,676,040 - 29,721,613 (-)NCBIGRCr8
mRatBN7.239,277,955 - 9,323,531 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl39,278,086 - 9,323,531 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx312,332,077 - 12,388,087 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0320,915,306 - 20,971,319 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0319,170,646 - 19,226,660 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.033,905,562 - 3,951,015 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl33,905,453 - 3,951,025 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.039,266,663 - 9,311,575 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.434,631,797 - 4,677,640 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.134,632,997 - 4,677,652 (-)NCBI
Celera34,097,915 - 4,143,369 (-)NCBICelera
Cytogenetic Map3p13NCBI
Notch1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555134,225,956 - 4,263,259 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555134,225,939 - 4,264,875 (+)NCBIChiLan1.0ChiLan1.0
NOTCH1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2112,838,339 - 2,890,794 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan192,840,674 - 2,893,129 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09107,568,670 - 107,621,032 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19136,544,639 - 136,595,511 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9136,544,639 - 136,598,740 (-)Ensemblpanpan1.1panPan2
Notch1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947202,040,997 - 202,083,042 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366691,292,088 - 1,332,428 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366691,292,016 - 1,334,061 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NOTCH1
(Sus scrofa - pig)		 No map positions available.
NOTCH1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1121,656,815 - 1,707,566 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl121,656,918 - 1,709,585 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660583,509,673 - 3,610,304 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Notch1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247601,634,702 - 1,676,531 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247601,636,331 - 1,676,398 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in NOTCH1
508 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000031242   ⟹   ENSCAFP00000029073
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl948,974,757 - 49,017,277 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845009722   ⟹   ENSCAFP00845007602
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl949,851,628 - 49,894,186 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845009762   ⟹   ENSCAFP00845007633
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl949,851,970 - 49,894,186 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845009797   ⟹   ENSCAFP00845007659
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl949,853,973 - 49,894,186 (+)Ensembl
RefSeq Acc Id: XM_038486885   ⟹   XP_038342813
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1948,633,237 - 48,676,758 (+)NCBI
RefSeq Acc Id: XM_038548751   ⟹   XP_038404679
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0948,974,423 - 49,017,941 (+)NCBI
RefSeq Acc Id: XM_038612681   ⟹   XP_038468609
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0948,926,759 - 48,970,231 (+)NCBI
RefSeq Acc Id: XM_038614892   ⟹   XP_038470820
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha948,226,361 - 48,269,900 (+)NCBI
RefSeq Acc Id: XM_038677974   ⟹   XP_038533902
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0949,852,205 - 49,895,734 (+)NCBI
Ensembl Acc Id: ENSCAFP00000029073   ⟸   ENSCAFT00000031242
RefSeq Acc Id: XP_038342813   ⟸   XM_038486885
RefSeq Acc Id: XP_038468609   ⟸   XM_038612681
RefSeq Acc Id: XP_038533902   ⟸   XM_038677974
- UniProtKB: A0A8I3MTK6 (UniProtKB/TrEMBL),   A0A8P0TTH3 (UniProtKB/TrEMBL),   A0A8C0RBT3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038470820   ⟸   XM_038614892
- UniProtKB: A0A8I3MTK6 (UniProtKB/TrEMBL),   A0A8P0TTH3 (UniProtKB/TrEMBL),   A0A8C0RBT3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038404679   ⟸   XM_038548751
- UniProtKB: A0A8C0RBT3 (UniProtKB/TrEMBL),   A0A8I3MTK6 (UniProtKB/TrEMBL),   A0A8P0TTH3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845007659   ⟸   ENSCAFT00845009797
Ensembl Acc Id: ENSCAFP00845007602   ⟸   ENSCAFT00845009722
Ensembl Acc Id: ENSCAFP00845007633   ⟸   ENSCAFT00845009762
Protein Domains
EGF-like   LNR


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000019633 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030003383 UniProtKB/TrEMBL
  ENSCAFG00040015640 UniProtKB/TrEMBL
  ENSCAFG00845005453 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000031242.6 UniProtKB/TrEMBL
  ENSCAFT00000099663.1 UniProtKB/TrEMBL
  ENSCAFT00000108725.1 UniProtKB/TrEMBL
  ENSCAFT00030006390.1 UniProtKB/TrEMBL
  ENSCAFT00040028780.1 UniProtKB/TrEMBL
  ENSCAFT00845009722.1 UniProtKB/TrEMBL
  ENSCAFT00845009762 ENTREZGENE
  ENSCAFT00845009762.1 UniProtKB/TrEMBL
  ENSCAFT00845009797.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
  3.30.300.320 UniProtKB/TrEMBL
  3.30.70.3310 UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-like_CS UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
  Notch UniProtKB/TrEMBL
  Notch-like_dom_sf UniProtKB/TrEMBL
  NOTCH1_EGF-like UniProtKB/TrEMBL
  Notch_1 UniProtKB/TrEMBL
  Notch_C UniProtKB/TrEMBL
  Notch_Cell-Fate_Det UniProtKB/TrEMBL
  Notch_dom UniProtKB/TrEMBL
  Notch_NOD_dom UniProtKB/TrEMBL
  Notch_NODP_dom UniProtKB/TrEMBL
NCBI Gene NOTCH1 ENTREZGENE
PANTHER CRUMBS FAMILY MEMBER UniProtKB/TrEMBL
  DELTA-LIKE PROTEIN UniProtKB/TrEMBL
Pfam Ank UniProtKB/TrEMBL
  Ank_2 UniProtKB/TrEMBL
  Ank_4 UniProtKB/TrEMBL
  EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  hEGF UniProtKB/TrEMBL
  NOD UniProtKB/TrEMBL
  NODP UniProtKB/TrEMBL
  Notch UniProtKB/TrEMBL
PIRSF Notch UniProtKB/TrEMBL
PRINTS EGFBLOOD UniProtKB/TrEMBL
  LNOTCHREPEAT UniProtKB/TrEMBL
  NOTCH UniProtKB/TrEMBL
  NOTCH1 UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
  ASX_HYDROXYL UniProtKB/TrEMBL
  EGF_1 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  LNR UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
  DUF3454 UniProtKB/TrEMBL
  EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  NOD UniProtKB/TrEMBL
  NODP UniProtKB/TrEMBL
  SM00004 UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
  SSF48403 UniProtKB/TrEMBL
  SSF57184 UniProtKB/TrEMBL
  SSF90193 UniProtKB/TrEMBL
UniProt A0A8C0RBT3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MTK6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MY07_CANLF UniProtKB/TrEMBL
  A0A8I3NBP5_CANLF UniProtKB/TrEMBL
  A0A8P0PN70_CANLF UniProtKB/TrEMBL
  A0A8P0SP10_CANLF UniProtKB/TrEMBL
  A0A8P0TTH3 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:43898 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-15 NOTCH1  notch receptor 1    notch 1  Symbol and/or name change 5135510 APPROVED