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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3187
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Notch1
Name: notch receptor 1
Acc ID: CHEBI:81506
Term: 2,3,7,8-Tetrachlorodibenzofuran
Definition: A dibenzofuran that has formula C12H4Cl4O.
Chemical ID: MESH:C014211
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Notch1affects expressionISONotch1 (Mus musculus)6480464CTD2,3,7,8-tetrachlorodibenzofuran affects the expression of NOTCH1 mRNAPMID:18343893
Notch1increases expressionISONotch1 (Mus musculus)6480464CTD2,3,7,8-tetrachlorodibenzofuran results in increased expression of NOTCH1 mRNAPMID:20702594
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